Jobs › Companies › Worldwide Clinical Trials › Director, EPMO Resource Optimization (US)

About this Director, EPMO Resource Optimization (US) role at Worldwide Clinical Trials

Worldwide Clinical Trials · Onsite · Durham, North Carolina

Who we are

We’re a global, midsize CRO that pushes boundaries, innovates and invents because the path to a cure for the world’s most persistent diseases is not paved by those who play it safe. It is built by those who take pioneering, creative approaches and implement them with quality and excellence.

We are Worldwide Clinical Trials, and we are a global team of over 3,500+ experts, bright thinkers, dreamers and doers and, together, we are changing the way the world experiences CROs – in the best possible way.

Our mission is to work with passion and purpose every day to improve lives and we are looking for others who value this same pursuit.

Why Worldwide

We believe everyone plays an important role in making a world of difference for patients and their caregivers. From our hands-on, accessible leaders, to our cohesive and supportive teams, we are committed to enabling professionals from all backgrounds and experiences to succeed. We prioritize cultivating a diverse and inclusive environment that continues to promote collaboration and creativity. We are proud to be a workplace where people thrive by being themselves and are inspired to do their best work every day. Join us!

Make an Impact as a Director, EPMO Resource Optimization at Worldwide


As Director, EPMO Resource Optimization, you will play a critical role in shaping how the organization optimizes its global workforce to improve productivity, delivery effectiveness, operational efficiency, and financial performance. This is a highly visible leadership opportunity within the Enterprise Program Management Office, focused on enabling sustainable growth while enhancing service quality.


You'll lead the strategy, frameworks, and enterprise-wide initiatives that help the business maximize resource utilization and workforce effectiveness. By combining data-driven insights, financial rigor, and cross-functional collaboration, you'll drive measurable improvements across operations and delivery teams.


Working closely with leaders across Operations, Human Resources, Finance, IT, and other business functions, you'll champion transformation initiatives, accelerate execution, and help embed scalable optimization practices across the organization.

Where You'll Work


This is a Remote role open to candidates based in the United States. You will collaborate with global teams across multiple time zones, with travel not specified.


What You'll Do


  • Develop and implement an enterprise-wide resource optimization strategy and playbook focused on labor efficiency, productivity improvement, and global delivery optimization.
  • Establish scalable methodologies, frameworks, and best practices that improve workforce effectiveness and operational performance across the organization.
  • Identify, evaluate, and prioritize opportunities to optimize capacity, improve resource alignment, and enhance delivery outcomes.
  • Leverage data, automation, technology, and AI-enabled solutions to advance resource optimization initiatives and drive business value.
  • Build and manage financial models that size opportunities, establish targets, and measure productivity gains, cost avoidance, and realized value.
  • Partner with Finance and Human Resources to validate assumptions, track benefits realization, and quantify business impact.
  • Drive the development of dashboards and reporting tools that provide visibility into initiative progress, key metrics, and outcomes.
  • Lead cross-functional execution by aligning stakeholders, removing barriers, accelerating implementation, and driving accountability for results.
  • Facilitate enterprise-wide communication and coordination to ensure the successful delivery of strategic transformation initiatives.

What You'll Bring


  • Bachelor’s degree in Finance, Economics, Accounting, Business Administration, Organizational Development, Engineering, or a related field required; Master’s degree in a related field preferred.
  • Minimum of 10 years of experience in resource optimization, business transformation, management consulting, or a related discipline, including at least 5 years advising large, complex organizations on workforce strategy or organizational transformation.
  • Demonstrated success designing and leading structured labor optimization programs that deliver measurable business outcomes.
  • Deep expertise in financial modeling related to labor efficiency, productivity improvement, cost savings, cost avoidance, and value realization.
  • Strong knowledge of workforce strategy, organizational effectiveness, operational excellence, and global delivery models.
  • Proven ability to influence and collaborate with senior leaders across Operations, Human Resources, Finance, IT, and other business functions.
  • Experience applying change management principles within complex organizations and driving alignment from frontline teams through executive leadership.
  • Proficiency in English; strong written, verbal, and presentation communication skills. Familiarity with AI and automation technologies and their application to workforce optimization is highly desirable.

At Worldwide Clinical Trials, we are committed to fostering an inclusive and equitable workplace by providing transparent compensation.

The salary range for this position is annually (For hourly paid positions, the stated salary range reflects hourly rates):


United States of America - $141,500.00 - $281,500.00


The salary range provided is intended to give candidates an understanding of potential earnings. Compensation will fall within the provided range, and it not a guarantee of exact salary. The final salary will be determined based on relevant experience, performance, education, and internal equity. In addition to base salary, we offer a competitive benefits package depending on location. We ensure pay equity and transparency and comply with all applicable labor laws. Salary information will be discussed during the interview process, and we encourage candidates to inquire about compensation at any stage.

We love knowing that someone is going to have a better life because of the work we do. 

To view our other roles, check out our careers page at Discover a world of difference at Worldwide! For more information on Worldwide, visit www.Worldwide.com or connect with us on LinkedIn.

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About Worldwide Clinical Trials

This is who we are. We’re a team of clinicians, scientists, and researchers who want to make healthcare better. We were founded on an unwavering commitment to authentic, personalized attention. And today, as CROs consolidate and the industry changes rapidly, that personalized attention is more important than ever. We all came to this industry for different reasons, from different walks of life. If you ask any one of us why we’re here, you’ll get a different answer. And that’s what makes us special.

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