About the Job

We’re hiring a Regional Manager, Orthopedics to lead the selling and commercial efforts within a defined territory for our growing organization. This role will focus specifically on our Ossigraft portfolio of orthopedic products, driving revenue growth, expanding market share, and strengthening key customer relationships.

You will be responsible for executing the commercial strategy within your assigned territory by maintaining a strong and consistent presence in the field. On a daily basis, you’ll meet with surgeons, physicians, and clinical staff to promote the biologics portfolio, provide product education, and support clinical adoption. The role includes delivering presentations, conducting in-service training, and, when necessary, providing operating room case coverage to ensure proper product utilization and positive patient outcomes. The Regional Manager actively identifies opportunities to expand business within existing accounts while prospecting and developing new relationships across hospitals, ambulatory surgery centers, and specialty clinics.

Required Qualifications

• Bachelor’s degree (Business, Life Sciences, or related field preferred)
• 3–5 years of experience in medical device sales, specifically within the biologics space
• Proven track record of achieving or exceeding sales quotas
• Strong clinical acumen and ability to engage in high-level medical discussions
• Experience selling into operating rooms and hospital environments preferred
• Excellent communication, presentation, and negotiation skills
• Strong analytical and territory planning capabilities
• Ability to travel within the assigned region as needed (50-75%)
• Excellent written and oral communication skills
• Capability to operate with a high level of organization and excellent time management in a dynamic startup environment
• This position is field based, in the broader Midwest region; some ideal metro areas are Chicago, St Louis, Indianapolis, or Kansas City
  
  • Candidates must reside within 50 miles of a major airport

Preferred Qualifications

• 5+ years spinal hardware and/or biologics experience
• Foot & Ankle experience

Key Responsibilities

• Lead and execute regional sales strategy for the Ossigraft product portfolio
• Drive revenue growth and consistently achieve or exceed sales targets
• Identify and develop new business opportunities within hospitals, surgery centers, and physician offices
• Build and maintain strong relationships with surgeons, clinical staff, supply chain, and administrative stakeholders
• Provide product education, training, and in-service support to clinical teams
• Collaborate with marketing, operations, and executive leadership to align commercial initiatives
• Analyze regional performance metrics and develop action plans to optimize results
• Ensure compliance with company policies, regulatory standards, and industry guidelines
• Maintain accurate forecasting, pipeline management, and CRM documentation

In your first six months some projects you’ll work on include:

• Targeting and onboarding new distribution opportunities to drive revenue growth
• Meeting with customers and providing clinical sales support
• Working with key decision makers to facilitate hospital approvals and contracting
• Attending industry conferences and meetings

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

About the Job

We’re hiring an Executive Assistant & Office Manager to provide critical administrative support for our founder CEO and office support for our growing San Francisco office! Your primary responsibility will be working closely with the CEO across a wide range of topics and duties. This is a great opportunity for someone looking to leverage a background in support to make a meaningful impact at a mission driven startup. 

This role will set the stage for a positive experience in the office for all.  You will act as the first point of contact for visitors, oversee day-to-day office operations, and ensure the office is clean, well-stocked, and welcoming.  We are looking for someone who is consistently punctual and shows up with a positive attitude. 

Required Qualifications

• 5+ years of work experience, with at least 2 years in an administrative support role
• Strong interpersonal skills, able to strike a balance of professionalism and friendliness
• Excellent written and oral communication skills
• Enthusiasm for working in a demanding, fast-paced environment and an ability to independently develop solutions to problems as they arise
• Strong organizational skills, including the ability to set priorities, handle multiple tasks, and organize time effectively
• Comfort with the large variety of unpredictable tasks common at start-up
• This position is based in our San Francisco office; Hours are Monday - Thursday, 7:30 am - 4:00 pm, and 7:30 am to 2 pm on Fridays.
  • Most of our SF staff is onsite Monday - Thursday and remote on Fridays, and the Office Manager will take advantage of the quiet to handle deliveries, answer phone calls, maintain office cleanliness, restock items, and run errands for the CEO

Key Responsibilities

Executive Assistance (~70%)

• Provide general leverage and support to the CEO, including managing a broad range of internal and external projects as required in a startup environment 
• Ownership of the CEO’s business calendar: foresee scheduling conflicts, anticipate issues, communicate consistently (internally with the team and externally with customers, high-level business partners, investors, OPO partners, and YPO members) and ensure efficiency 
• Maintain a high level of confidentiality at all times both internally and externally
• Manage administrative functions including screening phone calls and proofreading documents, processing and managing expenses for the CEO
• Facilitate tactful communication with high-level business partners 
• Help in the planning and execution of logistics for meetings, trainings, special events and travel
• Book CEO business travel
• Assist with planning internal/external events (leadership retreats, company holiday parties, conferences)
• Order and/or pick up lunches for CEO; making tea and coffee for CEO
• Assist the CEO with tasks such as scheduling appointments (e.g. doctor’s appointments, haircuts, etc) and making reservations

Office Management (~30%)

• Open up the office by 7:30 AM each day, disarm the alarm, empty the dishwasher
• Handle administrative tasks such as answering calls, filing, scanning mail, errands to postal office/shipping arrangements, sending out virtual birthday cards
• Take out the trash bins and be able to carry the bins up and down the stairs
• Monitor office supplies inventory and place orders, making sure we never run out of supplies
• Manage team lunches, make coffee, and restock the company kitchen, set up treats to be delivered for meetings and birthdays
• Plan and organize SF monthly happy hour
• Greet visitors, manage candidates' onsite interviews, and answer the company's main line to direct calls/take messages
• Support meeting and conference room needs: maintain office cleanliness and make sure conference rooms are clean, tidy, stocked, and that trash is removed every day

Physical Requirements

• Must be able to lift, push, pull and/or carry up to 35 pounds
• Must be able to sit or stand for long periods of time. Regularly required to sit, stand, walk, climb, stoop, kneel, crouch; use hands to handle or feel; and reach with arms.
• Must be able to report to the office by 7:30 AM daily

In your first three months, some projects you’ll work on include:

• Working closely with the CEO to manage his calendar including internal and external meetings, e.g. investors, business partners, and clinics
• Ensuring the office environment is welcoming and well-stocked
• Arranging and setting up team monthly happy hours

The annual salary range for this role is $90,000 - $130,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements

About the Job

We are hiring a Director, Scientific Affairs who brings both scientific depth and a genuine passion for connecting people, evidence, and ideas. In this role, you'll be at the center of our clinical and commercial efforts; helping translate complex science into clear, compelling stories that move the field forward.

You'll partner closely with teams across Ossium to shape medical and scientific strategy, supporting the commercial launch of our novel cryopreserved bone marrow, and leading medical education and data communication work that actually changes how clinicians think about treating patients. Whether you're collaborating with individual clinical sites on evidence-generation projects or working alongside the commercial team to bring our flagship product to patients in need, you'll be the bridge between science and impact.

This is an excellent role for someone who thrives at the intersection of rigor and relationship-building; the ideal candidate is someone who can walk into a room of scientists, surgeons, or sales leads and speak everyone's language. 

This role reports directly to the Chief Medical Officer.

Required Qualifications

• MD/PhD in a life science/biomedical discipline with strong clinical experience
• 5+ years of industry experience 
• Proven ability to collaborate, partner, and influence across multiple functions and levels of leadership
• Demonstrated experience with manuscript and abstract writing and post hoc data analyses
• Experience working with MSLs and providing medical/scientific support to commercial teams
• Proven agility and adaptability in a fast-paced, results-driven startup environment
• Excellent written, verbal, and presentation communication skills
• Understanding of biostatistical concepts to analyze clinical trial data
• Comfortable with travel from 15% - 30%
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• Scientific or clinical expertise in hematologic malignancies, hematopoietic cell transplantation (HCT), or cell therapy
• Experience supporting product launch 
• Background in rare disease or a specialized therapeutic indication (e.g., bone marrow transplantation)
• Experience in clinical development or protocol support

Key Responsibilities

• Drive scientific communications internally and externally, including data dissemination, educational initiatives, and guideline/value-proposition development
• Assist with strategic publication planning and writing/preparing manuscripts, abstracts, and presentations
• Collaborate closely with Medical Science Liaisons (MSLs) to generate, synthesize, and communicate scientific insights from field interactions
• Assist with initiating and maintaining relationships with transplant MDs and PIs
• Lead evidence-generation initiatives (clinical, secondary analyses, real-world evidence) to enhance understanding of therapeutic benefit and value
• Serve as medical reviewer on the Promotional Review Committee and ensure scientific accuracy and compliance of promotional materials
• Support congress planning and KOL engagement efforts in partnership with the Medical Science Liaison team
• Provide strategic medical and scientific input into brand strategies, supporting product launches and ongoing commercialization activities
• Provide medical guidance to clinical operations teams and support cross-functional collaboration with Commercial, Market Access, Regulatory, and Clinical Development
• Generate and maintain proactive educational content to support internal training and external stakeholder engagement
• Travel as needed  to scientific meetings, clinical sites, or investigator interactions

In your first six months some projects you’ll work on include:

• Supporting authorship and submission of manuscripts and abstracts to major scientific meetings (e.g., ASH, TANDEM)
• Partnering with field and commercial teams to deliver clinical and scientific support for product-launch activities for HPC, Marrow
• Establishing relationships with individual sites and PIs to initiate evidence generation projects

This position has a salary range of $200,000 - $275,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

About the Job

We are hiring a Clinical Trial Manager to support the successful execution of our clinical trials and operations. In this role, you’ll take ownership of the day-to-day tactical management of ongoing studies, ensuring seamless trial implementation and monitoring.

You’ll play a key role in launching our PRESERVE II clinical trial, the long-term follow-up of PRESERVE I, and our HOPE expanded access program. This position is ideal for someone who thrives in a hands-on, fast-paced environment—someone eager to collaborate across teams and coordinate with internal partners, CROs, and external vendors to deliver excellence in every aspect of our trials.

This role reports to the Senior Director, Clinical Operations.

Required Qualifications

• Degree in Life Sciences & industry-sponsored clinical trial experience: 
  • BS & 3+ years
  • MS/MPH & 1+ years
• Experience with or managing CROs; either from within a CRO in a major role, or from a sponsor-side biotech or pharmaceutical company at the Clinical Trial Manager or Clinical Project Manager level
• Strong written and verbal communication skills, with the ability to share complex information clearly and effectively across teams and stakeholders
• Exceptional organizational and time management abilities, with comfort operating in a fast-moving, dynamic startup environment
• Proven capacity to manage multiple priorities simultaneously, maintaining accuracy and attention to detail
• A collaborative, execution-oriented mindset with the ability to build alignment and drive progress across cross-functional teams
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Ability to travel as needed (10% - 15%)
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• CRA/site coordinator experience
• Trial experiences in full life cycle of clinical trial
• Experience in cell therapy 
• Experience in rare disease; hematologic malignancies (specifically bone marrow transplant)

Key Responsibilities

• Serve as the primary liaison with the CRO supporting PRESERVE II study activities, ensuring alignment on timelines and deliverables
• Review and contribute clinical operations input to key study documents including protocols, investigator brochures, regulatory submissions, clinical study reports, and operational plans developed by CRO partners
• Oversee site feasibility and capability assessments in close collaboration with the CRO and cross-functional teams
• Support additional clinical programs and studies as assigned, working closely with the Senior Director, Clinical Operations to meet strategic and operational objectives
• Partner with cross-functional groups, including Transplant Operations, Regulatory Affairs, and other stakeholders to ensure seamless coordination and successful trial execution
• Help lead and monitor trial execution to ensure compliance with ICH/GCP guidelines, applicable regulations, and company policies
• Organize and lead internal clinical project meetings, fostering collaboration and keeping teams aligned on goals and progress

In your first six months some projects you’ll work on include:

• Driving completion of critical milestones for the start of PRESERVE II clinical trial
• Supporting the active PRESERVE I study long term follow up
• Collaborating internally with other functions for clinical study implementation
• Conducting clinical project team meetings

This position has a salary range of $145,000 - $165,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements