About the Job

We’re hiring a Regional Manager, Orthopedics to lead the selling and commercial efforts within a defined territory for our growing organization. This role will focus specifically on our Ossigraft portfolio of orthopedic products, driving revenue growth, expanding market share, and strengthening key customer relationships.

You will be responsible for executing the commercial strategy within your assigned territory by maintaining a strong and consistent presence in the field. On a daily basis, you’ll meet with surgeons, physicians, and clinical staff to promote the biologics portfolio, provide product education, and support clinical adoption. The role includes delivering presentations, conducting in-service training, and, when necessary, providing operating room case coverage to ensure proper product utilization and positive patient outcomes. The Regional Manager actively identifies opportunities to expand business within existing accounts while prospecting and developing new relationships across hospitals, ambulatory surgery centers, and specialty clinics.

Required Qualifications

• Bachelor’s degree (Business, Life Sciences, or related field preferred)
• 3–5 years of experience in medical device sales, specifically within the biologics space
• Proven track record of achieving or exceeding sales quotas
• Strong clinical acumen and ability to engage in high-level medical discussions
• Experience selling into operating rooms and hospital environments preferred
• Excellent communication, presentation, and negotiation skills
• Strong analytical and territory planning capabilities
• Ability to travel within the assigned region as needed (50-75%)
• Excellent written and oral communication skills
• Capability to operate with a high level of organization and excellent time management in a dynamic startup environment
• This position is field based, in the broader Midwest region; some ideal metro areas are Chicago, St Louis, Indianapolis, or Kansas City
  
  • Candidates must reside within 50 miles of a major airport

Preferred Qualifications

• 5+ years spinal hardware and/or biologics experience
• Foot & Ankle experience

Key Responsibilities

• Lead and execute regional sales strategy for the Ossigraft product portfolio
• Drive revenue growth and consistently achieve or exceed sales targets
• Identify and develop new business opportunities within hospitals, surgery centers, and physician offices
• Build and maintain strong relationships with surgeons, clinical staff, supply chain, and administrative stakeholders
• Provide product education, training, and in-service support to clinical teams
• Collaborate with marketing, operations, and executive leadership to align commercial initiatives
• Analyze regional performance metrics and develop action plans to optimize results
• Ensure compliance with company policies, regulatory standards, and industry guidelines
• Maintain accurate forecasting, pipeline management, and CRM documentation

In your first six months some projects you’ll work on include:

• Targeting and onboarding new distribution opportunities to drive revenue growth
• Meeting with customers and providing clinical sales support
• Working with key decision makers to facilitate hospital approvals and contracting
• Attending industry conferences and meetings

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

About the Job

We’re hiring an Executive Assistant & Office Manager to provide critical administrative support for our founder CEO and office support for our growing San Francisco office! Your primary responsibility will be working closely with the CEO across a wide range of topics and duties. This is a great opportunity for someone looking to leverage a background in support to make a meaningful impact at a mission driven startup. 

This role will set the stage for a positive experience in the office for all.  You will act as the first point of contact for visitors, oversee day-to-day office operations, and ensure the office is clean, well-stocked, and welcoming.  We are looking for someone who is consistently punctual and shows up with a positive attitude. 

Required Qualifications

• 5+ years of work experience, with at least 2 years in an administrative support role
• Strong interpersonal skills, able to strike a balance of professionalism and friendliness
• Excellent written and oral communication skills
• Enthusiasm for working in a demanding, fast-paced environment and an ability to independently develop solutions to problems as they arise
• Strong organizational skills, including the ability to set priorities, handle multiple tasks, and organize time effectively
• Comfort with the large variety of unpredictable tasks common at start-up
• This position is based in our San Francisco office; Hours are Monday - Thursday, 7:30 am - 4:00 pm, and 7:30 am to 2 pm on Fridays.
  • Most of our SF staff is onsite Monday - Thursday and remote on Fridays, and the Office Manager will take advantage of the quiet to handle deliveries, answer phone calls, maintain office cleanliness, restock items, and run errands for the CEO

Key Responsibilities

Executive Assistance (~70%)

• Provide general leverage and support to the CEO, including managing a broad range of internal and external projects as required in a startup environment 
• Ownership of the CEO’s business calendar: foresee scheduling conflicts, anticipate issues, communicate consistently (internally with the team and externally with customers, high-level business partners, investors, OPO partners, and YPO members) and ensure efficiency 
• Maintain a high level of confidentiality at all times both internally and externally
• Manage administrative functions including screening phone calls and proofreading documents, processing and managing expenses for the CEO
• Facilitate tactful communication with high-level business partners 
• Help in the planning and execution of logistics for meetings, trainings, special events and travel
• Book CEO business travel
• Assist with planning internal/external events (leadership retreats, company holiday parties, conferences)
• Order and/or pick up lunches for CEO; making tea and coffee for CEO
• Assist the CEO with tasks such as scheduling appointments (e.g. doctor’s appointments, haircuts, etc) and making reservations

Office Management (~30%)

• Open up the office by 7:30 AM each day, disarm the alarm, empty the dishwasher
• Handle administrative tasks such as answering calls, filing, scanning mail, errands to postal office/shipping arrangements, sending out virtual birthday cards
• Take out the trash bins and be able to carry the bins up and down the stairs
• Monitor office supplies inventory and place orders, making sure we never run out of supplies
• Manage team lunches, make coffee, and restock the company kitchen, set up treats to be delivered for meetings and birthdays
• Plan and organize SF monthly happy hour
• Greet visitors, manage candidates' onsite interviews, and answer the company's main line to direct calls/take messages
• Support meeting and conference room needs: maintain office cleanliness and make sure conference rooms are clean, tidy, stocked, and that trash is removed every day

Physical Requirements

• Must be able to lift, push, pull and/or carry up to 35 pounds
• Must be able to sit or stand for long periods of time. Regularly required to sit, stand, walk, climb, stoop, kneel, crouch; use hands to handle or feel; and reach with arms.
• Must be able to report to the office by 7:30 AM daily

In your first three months, some projects you’ll work on include:

• Working closely with the CEO to manage his calendar including internal and external meetings, e.g. investors, business partners, and clinics
• Ensuring the office environment is welcoming and well-stocked
• Arranging and setting up team monthly happy hours

The annual salary range for this role is $90,000 - $130,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements

About the Job

We’re hiring an Equipment Technician who will focus on critical equipment to ensure that our clinical production team has everything they need to process and bank life-saving bone marrow.  In this role, you’ll be responsible for a variety of facility and equipment cleaning, maintenance, installation, operation, and troubleshooting to keep operations running smoothly in our cGMP (current Good Manufacturing Practice) facility.  This is a hands-on role, and we’ll train you on Good Documentation Practices, preparing tools for sterilization, and other support tasks which are key for a biotech manufacturing facility. Restocking materials and reagents as well as cleaning equipment/tools and autoclaving may also be a part of your daily routine.

This role reports to the Facilities Manager, and will work closely with both the Facilities team and the Clinical Production team.

Required Qualifications

• High School Diploma
• Ability to solve technical and performance problems using information from a variety of sources
• Excellent written and oral communication skills
• Capability to operate with a high level of organization and excellent time management in a dynamic startup environment
• This is an hourly, non-exempt role based in our Indianapolis facility
• We are currently hiring for Monday through Friday 8am - 5pm

Preferred Qualifications

• Experience working hands-on with laboratory/clinical equipment

Key Responsibilities

• Perform scheduled maintenance inspections and assurance inspections on equipment to ensure safe and effective operating conditions
• Assist with qualification of new equipment
• Test and calibrate components using a variety of manuals, troubleshooting techniques, and code requirements
• Perform routine preventative maintenance and calibrations of equipment
• Assist with cleaning, calibration, and maintenance of quality control, production, and research lab equipment, including non-routine maintenance and scheduling service or calibration with outside vendors as needed
• Assist in repair and replacement of complex medical equipment and systems
• Install and test a variety of medical and research equipment
• Diagnose equipment malfunctions with accuracy
• Perform activities in accordance with current GDP and cGMP 
• Recognize and communicate production and work environment issues/observations to supervisory staff in a timely manner

In your first six months some projects you’ll work on include:

• Training on gowning and cleaning practices for the cleanroom support areas
• Shadowing Clinical Production personnel and observe processing 
• Assisting Clinical Production team in developing improved tool cleaning procedures
• Learning the basics of safety, sterility, and the general flow of our methods and operations
• Understanding our freezers (-80° & -190°) and how they operate, fill and alarm
• Gaining familiarity with switching out Co2 and LN2 tanks

Physical Requirements

• Requires training in blood borne pathogen safety measures; new hires will be given the option of Hepatitis B vaccination
• Requires standing, walking, pushing, kneeling, twisting and reaching
• Must be able to work in a moderately noisy environment
• Must be able to work around biohazardous materials and chemicals 
• Must be able to lift, push, pull and/or carry up to 25 lbs
• Must be able to use hands and fingers to handle and feel objects, tools, and controls
• Must be able to sit or stand for long periods of time
• Regularly required to sit, stand, walk, climb, stoop, kneel, crouch; use hands to handle or feel; and reach with arms

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements

About the Job

We’re hiring a Medical Science Liaison (MSL) to support pre-launch medical affairs activities for our proprietary cryopreserved hematopoietic progenitor cell (HPC) bone marrow graft product that will be available through an on-demand donor bank.  This role will play a critical part in shaping scientific understanding, building transplant-center readiness, and establishing Ossium’s medical presence ahead of commercial availability.

This is a hands-on, field-based role, focused on deep scientific engagement with priority allogeneic BMT centers, investigator education, and support of evidence-generation efforts. You will serve as a scientific expert on Ossium’s HPC, Bone Marrow platform, supporting pre-launch medical strategy through high-quality scientific exchange, clinical insight gathering, and collaboration with internal teams. This role reports to the Chief Commercial Officer.

Required Qualifications

• Advanced degree (MD, DO, PhD, PharmD, or equivalent)
• Minimum 3-5 years relevant experience as an MSL or in a scientific field facing role within biotech or pharma
• Strong background in bone marrow transplantation, hematologic malignancies, cell therapy, or immunology
• Ability to operate with a high level of organization and time management in a dynamic startup environment.
• Willingness to travel up to ~80% 
• This role is a field based position based in the Southeastern United States and requires regular travel to transplant centers across the region; candidates must reside within 50 miles of a major airport to facilitate this travel

Preferred Qualifications

• Direct experience in allogeneic BMT, HPC grafts, or cell-therapy launches
• Experience supporting pre-commercial or first-launch programs
• Familiarity with transplant center workflows, registries, and guideline development
• Existing relationships within the BMT community

Key Responsibilities

• Act as the primary medical liaison for designated transplant centers within an assigned territory
• Conduct non-promotional scientific exchanges regarding cryopreserved bone marrow
• Educate investigators and transplant teams on Ossium’s banking, matching, and logistics model to support early awareness and readiness
• Develop and maintain strong relationships with key transplant physicians, program directors, and cell-therapy stakeholders
• Identify and cultivate future investigators,  advisory board participants and speakers for Ossium programs
• Collect structured medical insights to inform clinical strategy, launch planning, and evidence needs
• Support ongoing and planned clinical studies as needed per clinical team, expanded access programs, and registry efforts related to HPC, Bone Marrow
• Facilitate investigator-initiated research (IIR) discussions in alignment with medical strategy
• Assist with site education related to protocol understanding and study conduct
• Support major hematology and transplant congresses (e.g., ASH, TANDEM, local chapters) and engage with advocacy groups
• Contribute to the development and review of medical materials and scientific content; support internal training
• Partner closely with Clinical Development, Regulatory, Manufacturing, and Commercial teams to ensure medical alignment

In your first six months, some projects you’ll work on include:

• Becoming a subject-matter expert in Ossium’s HPC, Bone Marrow (cryopreserved) platform
• Establishing scientific relationships with priority transplant centers and KOLs
• Supporting pre-launch congress activity and medical engagement planning
• Contributing medical insights to refine positioning, evidence gaps, and launch readiness

We Offer a Full Slate of Employee Benefits Including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental, and vision coverage
• Four weeks of PTO accrued annually (vacation & sick time) + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership and recreational sports reimbursements

About the Job

This is a high-impact leadership role responsible for end-to-end supply chain and logistics operations supporting our manufacturing site and patient-facing fulfillment. As the Director of Supply Chain and Logistics, you will lead material planning, procurement, inventory management, cold chain logistics, and order fulfillment to ensure reliable, compliant, and efficient product delivery.

You will partner closely with Manufacturing, Quality, Engineering, MSAT, Sales, and Commercial teams to ensure seamless integration between supply and demand, positioning Supply Chain and Logistics teams as both an operational backbone and a strategic enabler of growth. As a key member of the Site Operations Team and leader of our Downstream Core Team, you will drive disciplined execution, visibility, and continuous improvement across the organization.

This role is ideal for a leader who thrives in complex, regulated environments, builds scalable systems, and is energized by ensuring life-saving products reach patients reliably and on time. The position reports directly to the SVP of Manufacturing Operations.

Required Qualifications

• Bachelor’s degree in Supply Chain, Operations, Engineering, Business, or related field
• 10+ years of experience in supply chain, logistics, or operations in a regulated manufacturing environment (pharma, biotech, medtech preferred)
• 5+ years of people management experience leading supply chain or logistics teams
• Strong understanding of GMP/GTP requirements as they relate to materials, storage, and distribution
• Experience with inventory planning, procurement, and supplier management including ERP/MRP systems and inventory planning tools
• Proven track record of improving service levels, reducing shortages, and optimizing inventory
• Strong analytical, problem-solving, and communication skills

Preferred Qualifications

• Experience supporting commercial-scale pharmaceutical or biotech manufacturing environments
• Experience with cold chain, time-sensitive distribution, and external logistics provider management
• Familiarity with S&OP/S&OE processes and cross-functional demand–supply alignment
• Experience driving supply chain optimization through automation, digital tools, or advanced analytics
• Lean or Six Sigma certification with demonstrated application in supply chain environments
• Experience supporting regulatory inspections (FDA, AATB, or equivalent)

Key Responsibilities

• Lead, mentor, and develop a high-performing supply chain and logistics teams across procurement, planning, inventory, and fulfillment
• Own end-to-end material flow from supplier through manufacturing to patient delivery
• Ensure reliable supply of materials and on-time fulfillment of finished goods to meet patient demand
• Establish and maintain inventory strategies that balance availability, risk, and working capital
• Oversee cold chain logistics, shipping, and distribution, ensuring product integrity and compliance
• Manage supplier relationships, including performance, risk, and continuity of supply
• Drive S&OE processes to align demand, supply, and execution across the site
• Identify and mitigate supply chain risks, including shortages, delays, and capacity constraints
• Partner with Manufacturing, QA, and Engineering to support production and capacity scaling
• Lead continuous improvement initiatives to increase service level, reduce cost, and improve efficiency
• Ensure compliance with GMP/GTP, internal procedures, and regulatory expectations
• Support audits and represent Supply Chain during regulatory inspections
• Develop long-term supply chain strategy aligned with commercial growth and new product launches
• Lead the site’s cross-functional Downstream Core Team, overseeing Release and Distribution processes to ensure reliable, compliant product availability
• Travel (domestic and international) when required (<10%) to support supply chain and logistics planning or projects

In your first six months some projects you’ll work on include:

• Assess current inventory levels, service levels, and supply chain risks across all products
• Strengthen supplier management and sourcing strategies for critical materials
• Optimize cold chain logistics performance, including carrier reliability and cost
• Develop a 12-24 month supply chain roadmap aligned with growth and product launches

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements

About the Job

This is a high-impact leadership role at the center of our manufacturing and technical operations. As the Senior Manager of Engineering, you will lead the engineering and maintenance function supporting GMP/GTP manufacturing, ensuring equipment, processes, and systems remain reliable, compliant, and scalable as we grow.

You will partner closely with Production, Manufacturing, Quality, Supply Chain, MSAT, and Facilities to position Engineering as both a technical problem solver and a strategic enabler of safe, high-quality, and reliable product supply. As a key member of the Site Operations Team, you will drive disciplined execution, risk-based decision-making, and continuous improvement across the site.

This role is ideal for a technical leader who thrives in complex, regulated environments, builds strong and accountable teams, and is energized by modernizing systems to support increasing production demand and new product launches. The position reports directly to the SVP of Manufacturing Operations.

Required Qualifications

• Bachelor’s degree in Engineering and 8+ years of experience in pharmaceutical or biotech manufacturing OR 12+ years of relevant engineering experience in a regulated manufacturing environment
• 4+ years of people management experience leading engineers or technical staff
• Strong working knowledge of CGMP/CGTP requirements and engineering support in regulated aseptic or sterile manufacturing environments
• Experience with equipment qualification (IQ/OQ/PQ), validation, and change controls
• Proven track record of improving equipment reliability and reducing unplanned downtime
• Strong project management, documentation, and communication skills
• Experience with root cause analysis, FMEA, and SOP development
• This position is based full time onsite in our Indianapolis facility

Preferred Qualifications

• Experience supporting commercial-scale pharmaceutical or biotech manufacturing, including tech transfers, in multiple functional areas
• Familiarity with computerized maintenance management systems (CMMS)
• Experience leading capital projects and facility expansions
• Lean or Six Sigma certification
• Experience implementing automation and digital engineering solutions
• Experience interacting with regulatory inspectors (FDA, EMA, or equivalent)
• Expertise in business intelligence and analytics (Tableau, Power BI, SQL)

Key Responsibilities

• Lead, mentor, and develop a high-performing engineering team including facilities, validation, maintenance, and automation personnel
• Be a key member of our Site Operations Team, ensuring reliable supply of product to patients
• Own equipment lifecycle management including design input, commissioning, qualification, maintenance strategy, and retirement
• Oversee capital projects from concept through execution, ensuring scope, budget, and timelines are achieved
• Establish and improve preventive maintenance and reliability programs to reduce downtime and deviation risk
• Partner with Manufacturing, QA, and MSAT to support process improvements and capacity expansion
• Ensure engineering compliance with CGMP/CGTP, safety standards, and internal procedures
• Lead root cause investigations related to equipment, utilities, and facility systems
• Drive data-based reliability improvements using trend analysis and KPIs
• Support inspection readiness and represent Engineering during regulatory audits
• Develop long-term facility and infrastructure strategy aligned with commercial growth plans
• Travel (domestic and international) when required (<10%) to support other sites

In your first six months some projects you’ll work on include:

• Assessing current equipment reliability, PM effectiveness, and engineering KPIs
• Implementing a new CMMS software platform
• Identifying and prioritizing capital investments to support production growth
• Standardizing engineering documentation and technical standards
• Developing a 12-24 month engineering roadmap aligned to commercial scale and regulatory readiness

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements

About the Job

This position provides technical support and execution of tasks within Ossium Health’s Clinical Production group relating to preparation of human bone marrow-derived materials for pre-clinical and clinical use. Tasks require following standard operating procedures (SOPs) to process human tissue in an ISO7 cleanroom environment for Ossium’s bone marrow and tissue products. Position requires basic judgment in resolving problems, effective communication with coworkers and management, and close attention to detail.

Required Qualifications

• High school diploma
• Excellent written and oral communication skills
• Capability to operate with a high level of organization and time management in a dynamic startup environment
• High level of attention to detail in checking work and information for accuracy and quality
• Reliable and able to produce consistent, high quality work
• Great work ethic, positive attitude, and ability to work as part of a team

Preferred Qualifications

• Hands on laboratory experience working in a biological safety cabinet, pipetting, preparing reagents, and using lab equipment
• Experience working in a cleanroom environment, research laboratory, cell therapy, tissue banking, blood banking, or a closely-related industry

Key Responsibilities

• Perform production tasks in accordance with GMPs as operator or verifier in the production of tissue and/or bone marrow products in an ISO7 cleanroom environment. Tasks include tissue receipt, tissue processing, and cell processing utilizing some automated equipment while completing documentation in real time
• Maintain cleanrooms and production suite, including but not limited to routine and non-routine cleaning of biological safety cabinets, cleanrooms and equipment, environmental monitoring of cleanrooms, and continuous monitoring of equipment
• Maintain cryogenic freezers and product inventory using an electronic inventory system
• Collaborate with coworkers and supervisor to effectively troubleshoot equipment and process issues using critical thinking skills
• Participate in development and tech transfer activities related to new or enhanced processes in the production facility

Physical Requirements

• Must be able to work aseptically in controlled environments requiring special gowning (ie. over the head, face, hands, feet and body)
• Must be able to work in a moderately noisy environment
• Must be able to work around biohazardous materials and chemicals
• Must be able to lift, push, pull and/or carry up to 25 lbs
• Must be able to use hands and fingers to handle and feel objects, tools, and controls
• Must be able to sit or stand for long periods of time. Regularly required to sit, stand, walk, climb, stoop, kneel, crouch; use hands to handle or feel; and reach with arms.

Schedule

• Full-time (40 hours per week) onsite in our Indianapolis facility
• This is an hourly, non-exempt role that is eligible for overtime
• 8 hour shifts, Monday through Friday schedule with two different schedules open:
  • 1st shift: 6 am start time
  • 2nd shift: 10 am start time
• Some holiday and overtime work required

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements 

About the Job

We’re looking for a Quality Control Associate to provide technical support and execution of tasks within Ossium Health’s Quality Control Laboratory, relating to testing of human bone marrow-derived materials for pre-clinical and clinical use. Successful candidates have a basic understanding of the theory, concepts and regulations behind cGMP regulations and CLIA regulations. You’ll help to ensure that we maintain the highest levels of quality and safety standards on a day to day basis. This is a great opportunity for detail-oriented individuals looking to further a career in biotechnology and quality systems.

Required Qualifications

• BS or BA in biological sciences
• High level of attention to detail in both operations and documentation
• Reliable and able to produce consistent, high quality work
• Great communication skills and organization, able to work as part of a team
• Great work ethic and positive attitude
• Strong computer skills, including Microsoft Office
• Strong attention to detail and observational skills
• This position is based full time in our Indianapolis facility

Preferred Qualifications

• Experience working in a CLIA laboratory, cell therapy, tissue banking, blood banking, or other relevant industry experience
• Experience with flow cytometry, hematopoietic colony forming unit assay, and ELISA
• Exceptional laboratory technique
• Understanding of 21 CFR 210, 21 CFR 211, 21 CFR 1271, 42 CFR 493, AATB Standards, and other GMP requirements
• Strong knowledge of data analysis and statistical methods
• Hands-on experience in MasterControl, including the quality modules and production records

Key Responsibilities

• Perform tests as operator or verifier in the testing of bone marrow derived products 
• Maintain data and documentation related to testing of bone marrow derived products obtained internally or externally
• Update product and sample inventory using an electronic inventory system
• Assist in shipping of testing samples and product from bank
• Perform routine and advanced duties required to clean, maintain and operate testing equipment and storage equipment
• Assist in drafting and revising of departmental procedures
• Work with coworkers and supervisor to effectively troubleshoot equipment and testing issues

Physical Requirements

• Must be able to work aseptically in controlled environments requiring special gowning (i.e. over the head, face, hands, feet and body)
• Must be able to work in a moderately noisy environment
• Must be able to work around biohazardous materials and chemicals
• Must be able to lift, push, pull and/or carry up to 25 lbs
• Must be able to use hands and fingers to handle and feel objects, tools, and controls
• Must be able to sit or stand for long periods of time. Regularly required to sit, stand, walk, climb, stoop, kneel, crouch; use hands to handle or feel; and reach with arms.

Schedule

• Full-time (40 hours per week)
• This is an hourly, non-exempt role that is eligible for overtime
• Our QC lab is staffed for testing Monday through Friday, including holidays. The schedule for this position is 4 x 10 hour shifts either Monday-Thursday or Tuesday-Friday

We offer a full slate of employee benefits including:

• Competitive salaries
• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Four weeks of PTO accrued (vacation & sick time) annually  + 11 company holidays
• Employer paid life insurance and long term disability
• Gym membership/recreational sports reimbursements

About the Job

We are hiring a Director, Scientific Affairs who brings both scientific depth and a genuine passion for connecting people, evidence, and ideas. In this role, you'll be at the center of our clinical and commercial efforts; helping translate complex science into clear, compelling stories that move the field forward.

You'll partner closely with teams across Ossium to shape medical and scientific strategy, supporting the commercial launch of our novel cryopreserved bone marrow, and leading medical education and data communication work that actually changes how clinicians think about treating patients. Whether you're collaborating with individual clinical sites on evidence-generation projects or working alongside the commercial team to bring our flagship product to patients in need, you'll be the bridge between science and impact.

This is an excellent role for someone who thrives at the intersection of rigor and relationship-building; the ideal candidate is someone who can walk into a room of scientists, surgeons, or sales leads and speak everyone's language. 

This role reports directly to the Chief Medical Officer.

Required Qualifications

• MD/PhD in a life science/biomedical discipline with strong clinical experience
• 5+ years of industry experience 
• Proven ability to collaborate, partner, and influence across multiple functions and levels of leadership
• Demonstrated experience with manuscript and abstract writing and post hoc data analyses
• Experience working with MSLs and providing medical/scientific support to commercial teams
• Proven agility and adaptability in a fast-paced, results-driven startup environment
• Excellent written, verbal, and presentation communication skills
• Understanding of biostatistical concepts to analyze clinical trial data
• Comfortable with travel from 15% - 30%
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• Scientific or clinical expertise in hematologic malignancies, hematopoietic cell transplantation (HCT), or cell therapy
• Experience supporting product launch 
• Background in rare disease or a specialized therapeutic indication (e.g., bone marrow transplantation)
• Experience in clinical development or protocol support

Key Responsibilities

• Drive scientific communications internally and externally, including data dissemination, educational initiatives, and guideline/value-proposition development
• Assist with strategic publication planning and writing/preparing manuscripts, abstracts, and presentations
• Collaborate closely with Medical Science Liaisons (MSLs) to generate, synthesize, and communicate scientific insights from field interactions
• Assist with initiating and maintaining relationships with transplant MDs and PIs
• Lead evidence-generation initiatives (clinical, secondary analyses, real-world evidence) to enhance understanding of therapeutic benefit and value
• Serve as medical reviewer on the Promotional Review Committee and ensure scientific accuracy and compliance of promotional materials
• Support congress planning and KOL engagement efforts in partnership with the Medical Science Liaison team
• Provide strategic medical and scientific input into brand strategies, supporting product launches and ongoing commercialization activities
• Provide medical guidance to clinical operations teams and support cross-functional collaboration with Commercial, Market Access, Regulatory, and Clinical Development
• Generate and maintain proactive educational content to support internal training and external stakeholder engagement
• Travel as needed  to scientific meetings, clinical sites, or investigator interactions

In your first six months some projects you’ll work on include:

• Supporting authorship and submission of manuscripts and abstracts to major scientific meetings (e.g., ASH, TANDEM)
• Partnering with field and commercial teams to deliver clinical and scientific support for product-launch activities for HPC, Marrow
• Establishing relationships with individual sites and PIs to initiate evidence generation projects

This position has a salary range of $200,000 - $275,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

About the Job

We are hiring a Clinical Trial Manager to support the successful execution of our clinical trials and operations. In this role, you’ll take ownership of the day-to-day tactical management of ongoing studies, ensuring seamless trial implementation and monitoring.

You’ll play a key role in launching our PRESERVE II clinical trial, the long-term follow-up of PRESERVE I, and our HOPE expanded access program. This position is ideal for someone who thrives in a hands-on, fast-paced environment—someone eager to collaborate across teams and coordinate with internal partners, CROs, and external vendors to deliver excellence in every aspect of our trials.

This role reports to the Senior Director, Clinical Operations.

Required Qualifications

• Degree in Life Sciences & industry-sponsored clinical trial experience: 
  • BS & 3+ years
  • MS/MPH & 1+ years
• Experience with or managing CROs; either from within a CRO in a major role, or from a sponsor-side biotech or pharmaceutical company at the Clinical Trial Manager or Clinical Project Manager level
• Strong written and verbal communication skills, with the ability to share complex information clearly and effectively across teams and stakeholders
• Exceptional organizational and time management abilities, with comfort operating in a fast-moving, dynamic startup environment
• Proven capacity to manage multiple priorities simultaneously, maintaining accuracy and attention to detail
• A collaborative, execution-oriented mindset with the ability to build alignment and drive progress across cross-functional teams
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Ability to travel as needed (10% - 15%)
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• CRA/site coordinator experience
• Trial experiences in full life cycle of clinical trial
• Experience in cell therapy 
• Experience in rare disease; hematologic malignancies (specifically bone marrow transplant)

Key Responsibilities

• Serve as the primary liaison with the CRO supporting PRESERVE II study activities, ensuring alignment on timelines and deliverables
• Review and contribute clinical operations input to key study documents including protocols, investigator brochures, regulatory submissions, clinical study reports, and operational plans developed by CRO partners
• Oversee site feasibility and capability assessments in close collaboration with the CRO and cross-functional teams
• Support additional clinical programs and studies as assigned, working closely with the Senior Director, Clinical Operations to meet strategic and operational objectives
• Partner with cross-functional groups, including Transplant Operations, Regulatory Affairs, and other stakeholders to ensure seamless coordination and successful trial execution
• Help lead and monitor trial execution to ensure compliance with ICH/GCP guidelines, applicable regulations, and company policies
• Organize and lead internal clinical project meetings, fostering collaboration and keeping teams aligned on goals and progress

In your first six months some projects you’ll work on include:

• Driving completion of critical milestones for the start of PRESERVE II clinical trial
• Supporting the active PRESERVE I study long term follow up
• Collaborating internally with other functions for clinical study implementation
• Conducting clinical project team meetings

This position has a salary range of $145,000 - $165,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

About Ossium Health

Ossium Health’s mission is to improve human health, vitality, and longevity through bioengineering. We develop, process, and bank cell therapy products that harness the power of stem cell science to transform treatment for patients with blood and immune diseases. At Ossium, we empower our employees, uphold the highest standards of operational excellence, and strive to be a force for good in the world.

About the Role

The Tissue Recovery Specialist is an independent contractor role supporting Ossium Health’s vertebral body recovery program. Tissue Recovery Specialists are engaged when additional support is required to ensure timely donor recovery.  This is a unique level role for an individual with operating room or tissue recovery experience.

Key Responsibilities

• Respond promptly to Ossium communications regarding donor recovery availability
• Perform vertebral body recovery immediately following organ procurement or when permitted
• Develop in-depth knowledge of Ossium Health and recovery partner protocols to consistently ensure high quality performance
• Travel primarily by car, using either your own vehicle or a recovery partner’s vehicle if permitted, and potentially by plane to designated facilities where organ procurement is performed
• Coordinate closely with Organ Procurement Organization (OPO) staff
• Be available to recover a minimum of 4 cases per month to maintain competency level
• Document, recover, package, and personally deliver recovered tissue to Ossium’s processing facility in Indianapolis
• Represent Ossium Health with professionalism to partners and clinical staff
• Consistently adhere to all safety standards, including proper use of PPE

This is not an on-call position. You will only be contacted when recovery coverage is needed. Upon notification, you may choose to accept the case if you are available to arrive within the required timeframe. 

The Tissue Recovery Specialist reports directly to the Manager of Recovery Services.

Required Qualifications

• Experience working in an OPO (organ, tissue, ocular recovery) or hospital operating room (OR) setting
• Ability to reliably travel (drive/fly) with limited notice (typically under 6 hours) primarily within the Indianapolis Metro area, while also being able to travel to other locations within Indiana; must possess valid driver’s license
• Flexibility to work outside standard business hours (evenings, nights, weekends, or holidays) as needed
• Proficiency in recovery techniques with strong attention to aseptic practice
• Strong knowledge of anatomy and medical terminology
• Excellent communication skills with a professional, approachable demeanor
• Reliability, responsiveness, and attention to detail
• Employment offers are contingent upon successful completion of a background check and reference verification.

Preferred Qualifications

• 2+ years of organ, tissue, ocular recovery, or hospital OR experience
• Associate’s degree in a science or healthcare-related field
• Certified Tissue Bank Specialist (CTBS)

Physical Requirements

• Training in bloodborne pathogen safety required (Hepatitis B vaccination available)
• Ability to work aseptically in controlled environments
• Comfort working around biohazardous materials and chemicals
• Ability to lift, push, pull, or carry up to 50 lbs
• Manual dexterity to handle surgical instruments, tools, and recovery equipment.
• Ability to sit, stand, walk, climb, stoop, kneel, crouch, and reach as needed during recoveries