About the Job

We are hiring a Director, Scientific Affairs who brings both scientific depth and a genuine passion for connecting people, evidence, and ideas. In this role, you'll be at the center of our clinical and commercial efforts; helping translate complex science into clear, compelling stories that move the field forward.

You'll partner closely with teams across Ossium to shape medical and scientific strategy, supporting the commercial launch of our novel cryopreserved bone marrow, and leading medical education and data communication work that actually changes how clinicians think about treating patients. Whether you're collaborating with individual clinical sites on evidence-generation projects or working alongside the commercial team to bring our flagship product to patients in need, you'll be the bridge between science and impact.

This is an excellent role for someone who thrives at the intersection of rigor and relationship-building; the ideal candidate is someone who can walk into a room of scientists, surgeons, or sales leads and speak everyone's language. 

This role reports directly to the Chief Medical Officer.

Required Qualifications

• MD/PhD in a life science/biomedical discipline with strong clinical experience
• 5+ years of industry experience 
• Proven ability to collaborate, partner, and influence across multiple functions and levels of leadership
• Demonstrated experience with manuscript and abstract writing and post hoc data analyses
• Experience working with MSLs and providing medical/scientific support to commercial teams
• Proven agility and adaptability in a fast-paced, results-driven startup environment
• Excellent written, verbal, and presentation communication skills
• Understanding of biostatistical concepts to analyze clinical trial data
• Comfortable with travel from 15% - 30%
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• Scientific or clinical expertise in hematologic malignancies, hematopoietic cell transplantation (HCT), or cell therapy
• Experience supporting product launch 
• Background in rare disease or a specialized therapeutic indication (e.g., bone marrow transplantation)
• Experience in clinical development or protocol support

Key Responsibilities

• Drive scientific communications internally and externally, including data dissemination, educational initiatives, and guideline/value-proposition development
• Assist with strategic publication planning and writing/preparing manuscripts, abstracts, and presentations
• Collaborate closely with Medical Science Liaisons (MSLs) to generate, synthesize, and communicate scientific insights from field interactions
• Assist with initiating and maintaining relationships with transplant MDs and PIs
• Lead evidence-generation initiatives (clinical, secondary analyses, real-world evidence) to enhance understanding of therapeutic benefit and value
• Serve as medical reviewer on the Promotional Review Committee and ensure scientific accuracy and compliance of promotional materials
• Support congress planning and KOL engagement efforts in partnership with the Medical Science Liaison team
• Provide strategic medical and scientific input into brand strategies, supporting product launches and ongoing commercialization activities
• Provide medical guidance to clinical operations teams and support cross-functional collaboration with Commercial, Market Access, Regulatory, and Clinical Development
• Generate and maintain proactive educational content to support internal training and external stakeholder engagement
• Travel as needed  to scientific meetings, clinical sites, or investigator interactions

In your first six months some projects you’ll work on include:

• Supporting authorship and submission of manuscripts and abstracts to major scientific meetings (e.g., ASH, TANDEM)
• Partnering with field and commercial teams to deliver clinical and scientific support for product-launch activities for HPC, Marrow
• Establishing relationships with individual sites and PIs to initiate evidence generation projects

This position has a salary range of $200,000 - $275,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements

About the Job

We are hiring a Clinical Trial Manager to support the successful execution of our clinical trials and operations. In this role, you’ll take ownership of the day-to-day tactical management of ongoing studies, ensuring seamless trial implementation and monitoring.

You’ll play a key role in launching our PRESERVE II clinical trial, the long-term follow-up of PRESERVE I, and our HOPE expanded access program. This position is ideal for someone who thrives in a hands-on, fast-paced environment—someone eager to collaborate across teams and coordinate with internal partners, CROs, and external vendors to deliver excellence in every aspect of our trials.

This role reports to the Senior Director, Clinical Operations.

Required Qualifications

• Degree in Life Sciences & industry-sponsored clinical trial experience: 
  • BS & 3+ years
  • MS/MPH & 1+ years
• Experience with or managing CROs; either from within a CRO in a major role, or from a sponsor-side biotech or pharmaceutical company at the Clinical Trial Manager or Clinical Project Manager level
• Strong written and verbal communication skills, with the ability to share complex information clearly and effectively across teams and stakeholders
• Exceptional organizational and time management abilities, with comfort operating in a fast-moving, dynamic startup environment
• Proven capacity to manage multiple priorities simultaneously, maintaining accuracy and attention to detail
• A collaborative, execution-oriented mindset with the ability to build alignment and drive progress across cross-functional teams
• This position is based in our San Francisco office; we maintain a hybrid schedule of Monday - Thursday in the office, with Friday as a remote work day
• Ability to travel as needed (10% - 15%)
• Qualified candidates must be legally authorized to be employed in the United States; Ossium is unable to provide sponsorship for employment visa status (eg, H-1B or TN status) for this position, either now or in the future

Preferred Qualifications

• CRA/site coordinator experience
• Trial experiences in full life cycle of clinical trial
• Experience in cell therapy 
• Experience in rare disease; hematologic malignancies (specifically bone marrow transplant)

Key Responsibilities

• Serve as the primary liaison with the CRO supporting PRESERVE II study activities, ensuring alignment on timelines and deliverables
• Review and contribute clinical operations input to key study documents including protocols, investigator brochures, regulatory submissions, clinical study reports, and operational plans developed by CRO partners
• Oversee site feasibility and capability assessments in close collaboration with the CRO and cross-functional teams
• Support additional clinical programs and studies as assigned, working closely with the Senior Director, Clinical Operations to meet strategic and operational objectives
• Partner with cross-functional groups, including Transplant Operations, Regulatory Affairs, and other stakeholders to ensure seamless coordination and successful trial execution
• Help lead and monitor trial execution to ensure compliance with ICH/GCP guidelines, applicable regulations, and company policies
• Organize and lead internal clinical project meetings, fostering collaboration and keeping teams aligned on goals and progress

In your first six months some projects you’ll work on include:

• Driving completion of critical milestones for the start of PRESERVE II clinical trial
• Supporting the active PRESERVE I study long term follow up
• Collaborating internally with other functions for clinical study implementation
• Conducting clinical project team meetings

This position has a salary range of $145,000 - $165,000 annually. Ossium Health takes a market-based approach to pay. The successful candidate’s starting salary will be determined based on, but not limited to, job-related skills, experience, qualifications, and market conditions. This range may be modified in the future.

We offer a full slate of employee benefits including:

• Stock options
• 401(k) matching
• Medical, dental and vision coverage
• Generous paid time off + 11 company holidays
• Employer paid life insurance and long-term disability
• Gym membership/recreational sports reimbursements