Lead Product Manager, Clinical Genomics Engineering

Natera offers genetic risk assessment and diagnostic tests to patients through medical providers. The Clinical Genomics Engineering organization builds software that supports complex, regulated workflows spanning tertiary analysis workflows including variant  interpretation, clinical review, and reporting. As Natera scales across Women’s Health, Oncology, and Organ Health, delivering  cohesive, reliable, and compliant software experiences is foundational to clinical quality and commercial success.

Natera is seeking a Lead Product Manager to define and drive strategy for core components of the Results, Interpretation, and Reporting (RIR) platform. This role is responsible for shaping scalable, compliant, and cohesive clinical software systems that support complex genomics workflows across multiple business units. The Lead PM will operate as a platform-level owner, ensuring long-term architectural soundness, regulatory robustness, and measurable clinical and operational outcomes.

Initial Focus and Scope Evolution

The Lead Product Manager will lead cross-functional alignment across engineering, clinical, quality, and downstream systems to ensure RIR components operate as a cohesive, scalable platform. This role will identify systemic gaps, resolve cross-team tradeoffs, and drive architectural and workflow decisions that support long-term growth and regulatory compliance.

This role will initially own one or more RIR software components or initiatives, with responsibility for defining long-term strategy, aligning cross-component workflows, and ensuring scalable architecture across user-facing applications, data contracts, and backend services. The Lead PM will drive strategic investment decisions, establish standards for usability and reliability, and ensure systems meet evolving clinical, operational, and regulatory requirements.

As business needs evolve, this role will expand to influence and coordinate across multiple RIR components, driving cohesive workflow design, shared data standards, and platform-level scalability across Women’s Health, Oncology, and Organ Health.

Primary Responsibilities

• Define and drive multi-year product strategy and roadmap across one or more RIR components, ensuring alignment to clinical quality, regulatory requirements, and commercial scale objectives

• Influence platform-level technical direction in partnership with engineering leadership 

• Partner closely with software engineering, bioinformatics, clinical domain experts, quality, regulatory, and other product teams

• Translate business, clinical, and operational needs into clear, actionable product requirements

• Define and evolve end-to-end user workflows, including UI/UX requirements and supporting backend functionality

• Drive cross-team alignment on shared data contracts and workflow standards

• Mentor and raise the bar for product management within the RIR organization

• Own measurable improvements in clinical workflow efficiency, reliability, and operational scalability

• Establish prioritization frameworks that balance regulatory risk, clinical impact, technical scalability, and business outcomes across RIR investments.

• Develop and track quantitative metrics related to usability, performance, reliability, and adoption

• Lead delivery teams with clear strategic direction, ensuring requirements reflect long-term platform goals, validation readiness, and system interoperability.

• Proactively identify systemic risks, architectural constraints, and workflow inefficiencies that may limit scale or regulatory robustness, and lead cross-functional initiatives to resolve them

• Partner with Quality and Regulatory leadership to shape validation strategy, risk classification, traceability, and audit readiness for RIR software systems.

• Create clear, data-driven written proposals and presentations to support stakeholder alignment and decision-making

• Act as a subject matter expert for owned components, supporting design, testing, validation, rollout, and ongoing use

Qualifications

Required

• Bachelor’s degree in life sciences, engineering, computer science, statistics, or equivalent experience

• 7+ years of experience in software product management, including ownership of complex, multi-team or platform-level initiatives

• 5+ years experience working on production software in healthcare, clinical genomics, or other regulated lifesciences domains, with demonstrated impact on validation, compliance, and system scalability

• Demonstrated experience influencing engineering architecture and long-term technical investment decisions

• Proven ability to drive alignment across highly matrixed organizations without direct authority
  Track record of independently operating in ambiguous environments and establishing product direction
  

Preferred

• Experience with clinical genomics and variant processing and interpretation workflows

• Experience owning user-facing applications, tools, or operational software

• Familiarity working with backend services, APIs, or data-driven systems

Knowledge, Skills, and Abilities

• Ability to operate effectively at both tactical and strategic levels, connecting detailed execution to broader platform vision.

• Strong analytical skills with attention to quality, reliability, and user outcomes

• Leads technical design discussions and critically evaluates architectural tradeoffs to ensure scalability, reliability, and regulatory integrity

• Proven ability to influence without authority and drive alignment across teams

• Clear, concise written and verbal communication skills across technical and non-technical audiences

• Ability to manage multiple initiatives in a fast-paced, regulated environment

• Familiarity with Next Generation Sequencing concepts is beneficial

LOCATION: This role covers the Ohio Valley Region, including Southern Illinois, Indiana, Kentucky, Ohio, and Eastern Michigan.

We are seeking a highly motivated Clinical Oncology Specialist to join our newly formed Head and Neck Oncology specialty team. This is a unique opportunity to step into a high visibility, tumor specific role where you will help drive the adoption and continued growth of Signatera, our first of its kind MRD ctDNA technology that is transforming how cancer is monitored and managed.

In this role, you will serve as a strategic partner in the field and a key representative of Natera Oncology. You will work cross functionally to engage and build strong relationships with leading clinicians and key opinion leaders across integrated delivery networks, academic medical centers, hospital systems, and select community oncology practices.

Your primary stakeholders will include ENT physicians, Medical Oncologists, Oncology Surgeons, and Pathologists. Success in this role requires strong clinical insight, a deep understanding of the head and neck oncology landscape, and the ability to navigate complex healthcare environments while building meaningful, trust based partnerships.

We are looking for individuals who bring an entrepreneurial mindset, thrive in a fast paced environment, and are motivated by the opportunity to make a real impact on patient care. This role requires frequent travel throughout the region.

PRIMARY RESPONSIBILITIES:

• Learn Natera products, services, processes, policies, key internal teams, as well as competitor’s products, services, policies and practices, and payer/reimbursement landscape in the territory to be effective in the COS role.
• Identify Key Opinion Leaders (KOLs), hospitals, clinics and physicians that are appropriate for Natera products & services in the territory and gain their trust and business.
• Calls on oncologists and other medical personnel to provide product information for the sale of Natera’s Oncology diagnostics. 
• Capitalize on selling opportunities and/or to influence physicians, key opinion leaders, hospitals and clinics. 
• Responsible for the sale of the company’s oncology diagnostics products within an assigned territory or geographic region.
• Monitor, document and report on existing business as well as challenges and new opportunities. Escalate issues not resolved timely or to the satisfaction of the clients.
• Conduct business in an ethical & transparent fashion.
• Perform other duties as assigned.

QUALIFICATIONS:

• Bachelor’s degree required.
• 5+ years of experience with consistent success in Head and Neck Cancer, Medical Oncology, Surgical and/or Dx sales preferred.
• Knowledge of the targeted academic and community Oncology market, molecular diagnostics, personalized medicine and reimbursement.
• Ability to perform overnight travel.
• Demonstrated leadership capabilities, financial management and written and oral communications skills

KNOWLEDGE, SKILLS, AND ABILITIES:

• Excellent communication and presentation skills.
• Strategic and forward thinking.
• Effectively work in teams and are autonomous self-starters with experience in business analysis and have a command of Oncology and Healthcare business trends.
• Be able to demonstrate oncology clinical & medical expertise.

The total on-target earnings (OTE) package includes a competitive base salary along with uncapped quarterly commissions. Beyond OTE, the compensation also features a car allowance and Restricted Stock Units (RSUs).

****This is NOT a remote position, it will be onsite Monday - Friday in Livonia, MI ***

POSITION SUMMARY

A Sr Phlebotomist serves patients by identifying the best method for retrieving blood; preparing specimens for laboratory testing; and performing screening procedures. 

PRIMARY RESPONSIBILITIES

• Verifies test requisitions by comparing information with nursing station log; bringing discrepancies to the attention of unit personnel.

• Verifies patient by reading patient identification.

• Obtains blood specimens by performing venipunctures and finger sticks.

• Maintains specimen integrity by using aseptic technique, following department procedures; observing isolation procedures.

• Tracks collected specimens by initialing, dating, and noting times of collection; maintaining daily tallies of collections performed.

• Maintains quality results by following department procedures and testing schedule; recording results in the quality-control log; identifying and reporting needed changes.

• Maintains safe, secure, and healthy work environment by following standards and procedures; complying with legal regulations.

• Resolves unusual test orders by contacting the physician, pathologist, nursing station, or reference laboratory; referring unresolved orders back to the originator for further clarification; notifying supervisor of unresolved orders.

• Updates job knowledge by participating in educational opportunities; reading professional publications; maintaining personal networks; participating in professional organizations.

• Enhances phlebotomy department and hospital reputation by accepting ownership for accomplishing new and different requests; exploring opportunities to add value to job accomplishments.

• This role works with PHI on a regular basis both in paper and electronic form and have an access to various technologies to access PHI (paper and electronic) in order to perform the job

• Employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire.

• Must maintain a current status on Natera training requirements

• Logistical management/printing of patient reports for that area

• Billing question answering/triaging and follow-up with patients

• Scheduling pick ups from courier services - FedEx or Medspeed.

QUALIFICATIONS

• Minimum of 5 years of phlebotomy experience

• BS/BA degree (preferred)

• High School Diploma (or equivalent) required

• Phlebotomy Certificate (if required by State)

KNOWLEDGE, SKILLS, AND ABILITIES

• Ability to serve and protect the hospital community by adhering to professional standards, hospital policies and procedures, federal, state, and local requirements, and JCAHO standards.

PHYSICAL DEMANDS AND WORK ENVIRONMENT

• Work in an office setting with scrubs required

• The position requires tracking of each draw