Location: Remote / National

We are seeking a Senior Director, Health Systems Partnerships to lead the origination, development, and execution of enterprise partnerships with large health systems for Natera’s CRC and MCED early cancer detection portfolio.

This individual will be responsible for building and managing a robust pipeline, driving complex deal execution, and expanding adoption of early cancer detection solutions through the LDT phase and into FDA approval and commercial scale. The ideal candidate brings a strong track record of selling into complex health systems, navigating executive level stakeholders, and converting strategic opportunities into signed partnerships that drive measurable revenue growth.

This role will play a critical part in shaping Natera’s leadership in early cancer detection by securing foundational health system partnerships, accelerating adoption of CRC and MCED, and helping build the commercial engine needed to scale following FDA approval.

PRIMARY RESPONSIBILITIES:

Enterprise Sales & Deal Execution

• Own a national (or regional) book of business focused on large health systems and IDNs
• Build and manage a robust pipeline of partnership opportunities from prospecting through close
• Lead end-to-end deal execution, including stakeholder mapping, value articulation, proposal development, and contract negotiation
• Consistently deliver against partnership, revenue, and adoption targets

Health System Partnership Development

• Establish and grow C-suite and executive relationships (clinical, operational, financial) within health systems
• Identify and advance opportunities for enterprise-wide screening partnerships, pilots, and phased rollouts
• Position Natera as a long-term partner in early cancer detection, not just a vendor

Market Development (LDT Phase → FDA Approval)

• Drive early adoption and pilot partnerships while products are in the LDT phase
• Shape deals that can scale post-FDA approval, including system-wide expansion strategies
• Partner with Market Access and Medical Affairs to navigate evidence, reimbursement, and policy considerations in active deals

Cross-Functional Execution

• Partner closely with Medical Affairs, Market Access, Legal, and Operations to move deals forward and remove barriers
• Translate field insights into clear commercial feedback on product, evidence, and go-to-market strategy
• Ensure successful handoff and expansion post-close in partnership with implementation and account teams

Program Expansion & Account Growth

• Expand initial partnerships into multi-site, multi-year health system relationships
• Identify opportunities to increase test adoption, utilization, and program scale within existing accounts
• Track and communicate performance metrics and value realization to drive renewals and growth

QUALIFICATIONS:

• Bachelor’s degree in Life Sciences, Healthcare Administration, Business, Marketing, or a related field required; MBA or MHA (Master of Healthcare Administration) preferred.  
• 10+ years of successful enterprise healthcare sales experience, with a focus on large health systems, diagnostics, or oncology.
• 5+ years of direct management experience building and scaling high-performing enterprise teams.
• Proven track record of exceeding quotas and earning recognition (e.g., President’s Club) in complex, high-stakes environments.
• Expert understanding of health system economics, value-based care, and the transition from LDT to FDA-regulated markets.
• Travel required up to 40% - 60%

KNOWLEDGE, SKILLS, AND ABILITIES:

• Demonstrated success hiring, coaching, and developing top sales talent, including front-line managers and individual contributors
• Experience building and executing regional or national sales strategies aligned to company growth objectives
• Strong track record of driving accountability, forecasting accuracy, and performance management across teams
• Proven ability to lead through ambiguity, including early-stage commercialization or market development environments
• Experience partnering cross-functionally with Marketing, Market Access, Medical Affairs, and Product teams to drive go-to-market success
• Ability to influence and align executive stakeholders internally and externally

Preferred:

• Familiarity with value-based care and health system economics
• Existing relationships within large health systems or oncology leadership
• Experience commercializing products in pre- and post-reimbursement environments (e.g., LDT phase)
• Experience with diagnostics, screening, or early cancer detection (preferred)

Compensation & Benefits The package includes a competitive base salary, uncapped commissions, a car allowance program, and Restricted Stock Units (RSUs).

Our Mission

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to evolving or changing the management of disease worldwide. Our team is driven by a passion for science, innovation, and improving patient outcomes. With the expansion of Zenith™, our clinical exome and genome testing portfolio, we are seeking a strategic leader to help us redefine the diagnostic journey for rare disease patients.

Position Summary

As the Regional Director, Rare Disease, you will be at the forefront of Natera’s national expansion. You will lead a high-performing team of specialists dedicated to the Zenith™ portfolio, driving adoption in complex clinical environments. This is a high-impact leadership role focused on building a "best-in-class" culture, establishing deep institutional partnerships, and ensuring every patient has access to the most advanced genomic insights available.

What You’ll Do

• Build & Lead: Recruit, mentor, and inspire a regional sales team. You aren't just a manager; you are a coach dedicated to the professional growth of your team and the collective achievement of exceeding commercial targets.

• Drive Strategy: Develop and execute a regional business plan that aligns with Natera’s aggressive growth objectives. This includes territory optimization, resource management, and identifying high-growth market opportunities.

• KOL & Institutional Engagement: Build enduring relationships with Key Opinion Leaders (KOLs) in developmental pediatrics, neurology, and medical genetics. You will lead the strategy for institutional adoption within major Children’s Hospitals and rare disease centers.

• Launch & Scale: Lead the field execution for the Zenith™ portfolio, navigating complex sales cycles, pricing strategies, and contract negotiations to ensure Natera is the provider of choice for exome and genome testing.

• Cross-Functional Partnership: Collaborate closely with Marketing, Medical Affairs, and Managed Care to refine our value proposition and remove barriers to patient access.

• Operational Excellence: Utilize data-driven insights and CRM (Salesforce) metrics to forecast accurately and continuously improve regional performance.

Who You Are

• Experienced Leader: You have a minimum of 5 years in biotech, pharma, or diagnostic sales, with at least 3 years of proven success in a sales leadership role.

• Rare Disease Expert: You possess a deep understanding of the rare disease landscape, specifically within medical genetics or pediatric specialty markets. Experience with Children’s Hospitals is a major plus.

• Strategic Thinker: You don't just follow a plan; you build one. You excel at navigating the "gray areas" of a dynamic, evolving market.

• Mission-Driven: You are passionate about genomics and the impact that early, accurate diagnosis has on families and providers.

• Communicator: You have a "seat at the table" presence with the ability to influence both internal executives and external clinical leaders.

• Education: Bachelor’s degree required; advanced degree (MBA or MS in Life Sciences) is a plus.

Physical Demands & Work Environment

• This is a field-based position requiring frequent travel (up to 50% or more depending on the region) to support the team and engage with customers.

• Duties are typically performed in a home office and clinical/hospital environments.

Compensation & Benefits

Natera offers a competitive base salary with an uncapped commission structure. Our comprehensive benefits package includes:

• Medical, Dental, and Vision insurance.

• Generous Paid Time Off and 401(k) with company match.

• Monthly car allowance and travel reimbursement.

• Equity/Stock options for eligible roles.

Our Mission

Natera is a global leader in cell-free DNA (cfDNA) testing, dedicated to evolving or changing the management of disease worldwide. Our team is driven by a passion for science, innovation, and improving patient outcomes. With the expansion of Zenith™, our clinical exome and genome testing portfolio, we are seeking a strategic leader to help us redefine the diagnostic journey for rare disease patients.

Position Summary

As the Regional Director, Rare Disease, you will be at the forefront of Natera’s national expansion. You will lead a high-performing team of specialists dedicated to the Zenith™ portfolio, driving adoption in complex clinical environments. This is a high-impact leadership role focused on building a "best-in-class" culture, establishing deep institutional partnerships, and ensuring every patient has access to the most advanced genomic insights available.

What You’ll Do

• Build & Lead: Recruit, mentor, and inspire a regional sales team. You aren't just a manager; you are a coach dedicated to the professional growth of your team and the collective achievement of exceeding commercial targets.

• Drive Strategy: Develop and execute a regional business plan that aligns with Natera’s aggressive growth objectives. This includes territory optimization, resource management, and identifying high-growth market opportunities.

• KOL & Institutional Engagement: Build enduring relationships with Key Opinion Leaders (KOLs) in developmental pediatrics, neurology, and medical genetics. You will lead the strategy for institutional adoption within major Children’s Hospitals and rare disease centers.

• Launch & Scale: Lead the field execution for the Zenith™ portfolio, navigating complex sales cycles, pricing strategies, and contract negotiations to ensure Natera is the provider of choice for exome and genome testing.

• Cross-Functional Partnership: Collaborate closely with Marketing, Medical Affairs, and Managed Care to refine our value proposition and remove barriers to patient access.

• Operational Excellence: Utilize data-driven insights and CRM (Salesforce) metrics to forecast accurately and continuously improve regional performance.

Who You Are

• Experienced Leader: You have a minimum of 5 years in biotech, pharma, or diagnostic sales, with at least 3 years of proven success in a sales leadership role.

• Rare Disease Expert: You possess a deep understanding of the rare disease landscape, specifically within medical genetics or pediatric specialty markets. Experience with Children’s Hospitals is a major plus.

• Strategic Thinker: You don't just follow a plan; you build one. You excel at navigating the "gray areas" of a dynamic, evolving market.

• Mission-Driven: You are passionate about genomics and the impact that early, accurate diagnosis has on families and providers.

• Communicator: You have a "seat at the table" presence with the ability to influence both internal executives and external clinical leaders.

• Education: Bachelor’s degree required; advanced degree (MBA or MS in Life Sciences) is a plus.

Physical Demands & Work Environment

• This is a field-based position requiring frequent travel (up to 50% or more depending on the region) to support the team and engage with customers.

• Duties are typically performed in a home office and clinical/hospital environments.

Compensation & Benefits

Natera offers a competitive base salary with an uncapped commission structure. Our comprehensive benefits package includes:

• Medical, Dental, and Vision insurance.

• Generous Paid Time Off and 401(k) with company match.

• Monthly car allowance and travel reimbursement.

• Equity/Stock options for eligible roles.

POSITION SUMMARY
We are seeking experienced clinical sales leaders with five or more years of proven success in diagnostics or specialty laboratory services to join our Rare Disease team. The Rare Disease Specialist (RDS) will be both a frontline sales driver and a strategic business partner, leading market expansion and shaping how we launch and grow our exome and genome testing portfolio across the U.S.

As a Rare Disease Specialist, you will focus on engaging key clinical stakeholders, including developmental pediatricians, pediatric neurologists, genetic counselors, and medical geneticists, to drive awareness and adoption of our exome and genome testing solutions.

This role is designed for high performers who excel at complex clinical sales, thrive in entrepreneurial environments, and want to leave a lasting mark on the rare disease landscape.

PRIMARY RESPONSIBILITIES

• Own revenue growth and market development by driving direct sales to developmental pediatricians, pediatric neurologists, genetic counselors, and medical geneticists.

• Lead new product launches and accelerate the adoption of clinical exome and genome testing solutions.

• Build and sustain high-value relationships across Children’s Hospitals, rare disease networks, and clinical decision-makers.

• Design and execute territory business plans, with a clear focus on revenue acceleration and market share capture.

• Drive proposal development, pricing strategy, and contract negotiations to secure new business and formalize partnerships.

• Engage executive leadership with pipeline insights, opportunity prioritization, and performance metrics tied to rare disease growth.
  Serve as a clinical and technical resource, delivering education and training for providers and staff.

​KNOWLEDGE, SKILLS, AND ABILITIES

• Demonstrated success selling into Children’s Hospitals and/or rare disease markets.

• Track record of winning new business and launching new products in complex clinical environments.

• Ability to influence across stakeholders — from physicians to executives — with a consultative, solutions-driven approach.

• Entrepreneurial mindset, self-motivated, and driven to exceed aggressive growth targets.
  Proficiency with Microsoft Office, Gmail, and Salesforce.com.
  
  

The total compensation package includes an annualized, uncapped commission in addition to the base salary. Additionally, we offer a car allowance.