Mineralys Therapeutics is a publicly traded, clinical-stage biotechnology company focused on developing medicines to target diseases driven by abnormally elevated aldosterone. Our initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor that we are developing for cardiorenal conditions affected by abnormally elevated aldosterone, including hypertension and chronic kidney disease.
Mineralys is a fully remote company.
For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn.
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
National Sales Director
The National Sales Director (NSD) will serve as a senior field leader responsible for building and leading a high-performing commercial organization across a large U.S. geography in support of Mineralys’ first product launch. This role will lead a team of Regional Sales Directors and their sales teams, ensuring flawless launch execution, strong customer engagement, and achievement of business objectives.
The NSD will act as a strategic business partner to the VP of Sales and cross-functional leadership team, helping shape launch strategy, field execution plans, talent development, and organizational culture. This role requires a seasoned leader with deep launch experience, strong business acumen, and the ability to scale teams in a fast-paced biotech environment.
Key Responsibilities
Commercial Strategy / Launch Leadership
Field Leadership / Team Development
Cross-Functional Partnership
Business Operations / Compliance
Qualifications
Leadership Profile
Travel
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $260,000 - $285,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Director, Total Rewards
The Director, Total Rewards will lead the design, implementation, and administration of the company’s total rewards strategy—including compensation, equity, benefits, and wellness programs—to attract, motivate, and retain top scientific, technical, and commercial talent in a highly competitive biotech environment.
This role partners closely with executive leadership, HR business partners, Finance, Legal, and external advisors to ensure total rewards programs are market-competitive, scalable, compliant, and aligned with business objectives and company culture.
Success Measures
Travel
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $190,000 - $215,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Manager, Marketing Capabilities & Operations
As we prepare for our first commercial launch, we are seeking an experienced marketing operations professional who is energized by the opportunity to build from the ground up and establish foundational process capabilities.
Reporting to the Director of Marketing Capabilities & Operations, the Manager will play a critical role in enabling Mineralys Therapeutics’ first commercial launch. The Manager will help lead the day-day operational activities of the PRC (Promotional Review Committee) process to support the successful launch of lorundrostat.
This position helps manage material workflows, ensures that materials move efficiently through concept review, internal routing, regulatory/legal/medical review, and final deployment while maintaining compliance with process standards
The Manager will work cross‑functionally with internal and external stakeholders to ensure high quality submissions and timely review of materials in a fast‑moving, entrepreneurial launch environment.
Key Responsibilities
Marketing Production & Distribution
Process Optimization
Education and Experience
Travel
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $112,000 - $130,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Senior Director, Commercial Technology
At Mineralys, every decision we make is driven by a simple truth: the patient is waiting. Our vision is to reduce the burden of cardiorenal diseases by delivering targeted and transformative medications, creating more, healthy days for people with cardiorenal diseases — and commercial technology is a critical enabler of that vision, from launching with precision to sustaining impact at scale.
Reporting to the SVP, Digital and Transformation, the Senior Director, Commercial Technology is responsible for standing up the full commercial and medical affairs technology ecosystem from the ground up — on time, fit for purpose from day one, and ready to support an imminent launch. The operating principle is simple: SaaS-first, configuration-led, integration-smart.
This is not a role for someone who manages technology from a distance. It demands hands-on engagement, sound architectural judgment, and the ability to move fast without cutting corners.
Principal Responsibilities
Urgency — the patient is waiting
Collaboration — achieving goals through collective wisdom
Quality — in execution and actions
Trust — foundational to our success
Integrity — doing the right thing
Skills and Attributes
Supervisory Responsibility
Education and Experience
Travel
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $230,000 - $255,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Senior Director, Sales Training & Effectiveness
Reporting to the VP of Marketing, the Senior Director, Sales Training & Effectiveness will lead the strategy and execution of sales training and field effectiveness initiatives to ensure launch readiness and commercial performance. This role is responsible for shaping the field capability strategy—translating brand strategy into clear training priorities, defining field excellence standards, and enabling effective sales execution through onboarding, ongoing development, and performance optimization.
This role requires both strategic leadership and hands-on execution. The ideal candidate will be a self-starter with deep experience in sales training and commercial effectiveness, including launch planning, field onboarding, capability development, performance measurement, and cross‑functional leadership. Mineralys is seeking individuals who thrive in an entrepreneurial environment and are motivated to build exceptional field capabilities from day one.
Previous product launch leadership and experience in cardiovascular and/or chronic care markets is strongly preferred.
Key Responsibilities
Sales Training Strategy & Governance
Launch & Onboarding Excellence
Ongoing Capability Development
Sales Effectiveness & Performance Optimization
Cross-Functional Leadership
Qualifications
Travel
This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $215,000 - $250,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Digital Center of Excellence Project Manager
The Project Manager is responsible for leading the planning and delivery of enterprise systems implementation projects across Mineralys, from initiation through deployment and operational transition. This role owns end‑to‑end project execution across the System Development Lifecycle (SDLC), coordinating cross‑functional teams, vendors, and stakeholders to ensure systems are delivered on time, within scope, compliant with regulatory expectations, and ready for adoption.
Operating within a regulated life sciences environment, the Project Manager ensures projects align with IT governance, architecture, cybersecurity, data integrity, and electronic records requirements while supporting business objectives and inspection readiness.
Key Responsibilities
End‑to‑End IT Project Delivery
Cross‑Functional & Vendor Leadership
Compliance, Validation & Inspection Readiness
IT Governance & Enterprise Standards
Skills and Attributes
Qualifications
Travel
This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $140,000 - $157,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Vice President, Talent Management
Position Summary
The Vice President, Talent Management is a transformational leader who will design, build and lead a best-in-class, full-lifecycle talent organization at a pivotal moment in our company's history. As we transition from a development-stage company to a commercial enterprise, this leader will serve as the architect of our talent strategy — ensuring we attract, develop, engage and retain the exceptional people needed to bring life-changing therapies to patients.
This is a role for a builder — someone who thrives in ambiguity, can construct scalable systems from the ground up and brings the vision, energy and operational excellence to transform talent into a true competitive advantage. The VP, Talent will be a trusted advisor to the organization and a champion of our culture and values across every dimension of the employee experience.
Mineralys operates a hub-based remote model, with organizational anchors in Philadelphia, Boston and Boulder. This leader must be equally fluent in building distributed workforce practices and leveraging our hubs as cultural and community touchpoints.
Key Responsibilities
Talent Strategy & Leadership
Talent Acquisition & Employer Brand
Onboarding & Integration
Performance Management & Talent Development
Employee Experience & Culture
Workforce Planning & Organizational Effectiveness
Remote Work Infrastructure & Policy
Total Rewards Partnership
Compliance & Risk Management
Qualifications
Required
Preferred
Travel
This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $240,000 - $270,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Executive Director, Clinical Development
The Executive Director, Clinical Development will serve as the clinical lead for development program(s) and play a critical role in advancing pivotal studies, regulatory strategy, and submission readiness. This physician leader will provide medical and scientific oversight across the program lifecycle, from protocol design and study execution through data interpretation, regulatory interactions, and launch preparation.
This role requires a hands-on clinical development leader who thrives in a fast-paced biotech environment and can partner cross-functionally to drive high-quality execution with urgency.
Key Responsibilities:
Clinical Development Leadership
Medical Monitoring / Safety Oversight
Regulatory / Submission Support
Scientific / Cross-Functional Leadership
Team / Culture Leadership
Experience and Qualifications:
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $340,000 - $370,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Marketing Coordinator
Reporting to the VP, Marketing, this role is a hybrid position that combines senior-level administrative partnership with hands-on marketing coordination and team operations leadership. The Marketing Coordinator will provide day-to-day administrative support to the VP of Marketing while also serving as a key contributor to the execution of Mineralys’ marketing initiatives as the organization prepares for launch.
Operating in a fast-paced, entrepreneurial biopharmaceutical environment, this role requires someone who is highly organized, proactive, and comfortable shifting between strategic support, operational execution, and creative coordination. The ideal candidate is a self-starter who brings strong administrative fundamentals and an interest in driving coordination, communication, and execution across the broader Marketing and cross-functional teams.
This position will partner closely with cross-functional stakeholders including Sales, Medical Affairs, Market Access, Finance, Legal, and external agencies and vendors.
Principal Responsibilities
Administrative Support to the VP of Marketing & Department
Marketing Coordination & Execution
Systems, Process & Team Support
Education and Experience
Travel
Position eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $80,000 - $95,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
The Director, Medical Value & Outcomes (MVO) is a highly trained, field-based scientific expert responsible for engaging healthcare professionals and external decision makers through the exchange of clinical, scientific, economic, and research information related to Mineralys’ products and pipeline. The Director, MVO establishes, cultivates, and maintains professional relationships with key stakeholders—including healthcare professionals (HCPs), medical thought leaders, payors, managed care organizations, integrated delivery networks, and government entities.
In close partnership with the Market Access team, the Director, MVO supports strategic and tactical engagement with payors and key population-health decision makers. All activities are conducted in a scientifically objective and compliant manner, consistent with local, state, and national regulations, and industry guidelines.
This role functions as a core member of the Field Medical Affairs team and as a cross-functional collaborator who provides therapeutic area expertise, communicates value-based evidence, and delivers actionable insights to internal stakeholders.
Key Responsibilities
Education, Experience & Skills Requirements
Required Qualifications
Travel
Travel approximately ~20–30%, including domestic and occasional international travel to scientific congresses, investigator meetings, advisory boards, field team visits, Medical Affairs planning sessions, and cross-functional onsite meetings.
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $225,000 - $240,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
The Accounting Operations Senior Manager oversees procurement, accounts payable, payroll, and general operational accounting workflows. This role is responsible for ensuring accurate, efficient, and SOX‑compliant accounting operations across the organization. The ideal candidate brings deep operational expertise, strong leadership skills, and experience supporting a high‑growth life sciences environment. This remote position is based in Colorado, with regular bi-monthly, in person meetings with the Finance team in the Boulder region.
Principal Responsibilities
|
· Oversee procurement, accounts payable, payroll, and operational accounting functions with a focus on accuracy, compliance, and efficiency. · Manage end‑to‑end procure‑to‑pay processes ensuring alignment with policies, internal controls, and SOX requirements. · Lead and develop team members across procurement, AP, and payroll, fostering continuous improvement and operational excellence. · Optimize financial systems and tools, including NetSuite, TriNet, FloQast and Tipalti, to enhance automation, workflow efficiency, and reporting. · Partner with Finance, Legal, HR, and other stakeholders to ensure cross‑functional alignment and smooth operational processes. · Review and approve vendor contracts, purchase requests, payment batches, and payroll outputs. · Support month‑end and quarter‑end close through accrual review, reconciliations, and operational reporting. · Coordinate with internal and external auditors, serving as the subject‑matter expert for procurement, AP, and payroll processes. · Identify and implement improvements to strengthen internal controls, reduce risk, and scale operations for organizational growth. |
Skills and Attributes
|
1. Strong leadership skills with experience managing multiple operational functions. 2. Deep understanding of procurement, accounts payable, payroll processes, and accounting operations. 3. Proficiency with ERP and accounting automation systems, ideally NetSuite, TriNet, FloQast and Tipalti. 4. Ability to work in a fast‑paced, high‑growth environment with competing priorities. 5. Strong analytical, organizational, and problem‑solving skills. 6. Excellent communication skills with the ability to collaborate cross‑functionally. 7. High integrity and commitment to ethical and compliant business practices. 8. Comfort navigating ambiguity and implementing scalable operational solutions |
Travel
|
This position requires up to 10 % travel. Frequently travel is outside the local area and overnight. |
Education and Experience
|
· Bachelor’s degree in Accounting, Finance, Business Administration, or a related field; advanced degree preferred. · 8+ years of progressive experience in accounting operations including procurement, AP, and payroll. · Experience in the life sciences sector strongly preferred. · Experience working in a public company environment with familiarity in SOX compliance. · Strong expertise with ERP systems such as NetSuite and other tools such as TriNet, FloQast and Tipalti. · Demonstrated success in managing teams and improving operational workflows. |
This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $145,000 - $160,000
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
As we prepare for our first commercial launch, we are seeking an experienced marketing leader who is energized by the opportunity to build from the ground up, establish foundational capabilities, and shape the promotional medical education strategy for a best‑in‑class launch.
Reporting to the VP of Marketing, the Director, HCP Marketing & Thought Leader Engagement will serve as the strategic and operational leader responsible for defining and executing Mineralys’ promotional medical education and thought leader strategy across medical congresses, KOL engagement, advisory boards, speaker programs, and promotional medical education. This person will serve as the commercial lead for LCM planning and work cross-functionally to provide strategic insight into unmet needs, real world gaps, and future areas of opportunity.
This role plays a critical launch role establishing Mineralys within the cardio renal metabolic (CRM) and hypertension communities. We are seeking a leader with deep pharmaceutical marketing expertise, ideally with chronic care and launch experience, to ensure all engagement activities support pre-launch efforts, inform brand strategy, and accelerate launch readiness.
The ideal candidate can operate strategically while executing with precision in a lean, fast‑moving, launch‑focused environment.
Key Responsibilities
Travel
|
This position requires up to 30-40 % travel. Frequently travel is outside the local area and overnight. Some of the travel may be international. |
Education and Experience
|
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $200,000 - $220,000
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Ready to apply?
Apply to Mineralys Therapeutics
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“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”
Mineralys is a fully remote company.
Our Medical Affairs team is growing and hiring Senior Medical Science Liaisons in the US Northwestern Region (Washington, Oregon, Northern California, Idaho, Montana, and Nevada).
These field-based medical experts will support the US Medical Affairs team and will focus on establishing, developing, and maintaining strong collaborative relationships through scientific engagement with Key Opinion Leaders and Healthcare Practitioners within the assigned territory. This field position requires a strong background in the pharmaceutical industry, understanding the complexities of healthcare systems, and requires experience in an MSL or MSL like role in cardiovascular disease.
Requirements:
Must be located within driving distance of a major international airport; approx. 50 - 70% travel. Valid US driver’s license required, ability to travel without restrictions.
These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.
US Salary Range: $215,000 - $225,000
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