Pharmacologist Jobs in United States.
All active Pharmacologist roles based in United States.
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Senior Scientist/Principal Scientist, Quantitative Pharmacology (Contractor)
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Legend Biotech is a global biotechnology company dedicated to treating, and one day curing, life-threatening diseases. Headquartered in Somerset, New Jersey, we are developing advanced cell therapies across a diverse array of technology platforms, including autologous and allogenic chimeric antigen receptor T-cell, T-cell receptor (TCR-T), and natural killer (NK) cell-based immunotherapy. From our three R&D sites around the world, we apply these innovative technologies to pursue the discovery of safe, efficacious and cutting-edge therapeutics for patients worldwide.
Legend Biotech entered into a global collaboration agreement with Janssen, one of the pharmaceutical companies of Johnson & Johnson, to jointly develop and commercialize ciltacabtagene autolecuel (cilta-cel). Our strategic partnership is designed to combine the strengths and expertise of both companies to advance the promise of an immunotherapy in the treatment of multiple myeloma.
Legend Biotech is seeking Senior Scientist/Principal Scientist, Quantitative Pharmacology (Contractor) as part of the Research & Early Development team based in Somerset, NJ.
Role Overview
The position seeks a highly motivated and experienced quantitative pharmacologist to lead modeling and simulation efforts in support of gene and cell therapy products, with a focus on QSP and popPK modeling (Prior cell and gene therapy experience preferred).
Contract Duration: 12 Months
Key Responsibilities
- Lead QSP and popPK modeling activities across preclinical and clinical development stages.
- Play a pivotal role in shaping clinical pharmacology strategies, supporting regulatory submissions, and driving innovation in model-informed drug development (MIDD).
- Develop and apply mechanistic models to understand disease pathways, drug mechanisms, and patient variability.
- Conduct simulations to support dose selection, trial design, and exposure-response analyses.
- Collaborate cross-functionally with R&D, clinical, regulatory, and biostatistics teams.
- Author and review clinical pharmacology sections of regulatory documents (e.g., INDs, NDAs).
- Contribute to scientific publications and conference presentations.
Requirements
- R&D, Preclinical development, Clinical, CMC and regulatory
- MS/PhD/Pharm D in Pharmaceutical Sciences, Clinical Pharmacology, Applied Mathematics, Biomedical Engineering, or related quantitative discipline.
- 7+ years with MS degree or 3+ years with PhD/Pharm D degree of working experience in quantitative pharmacology or pharmacometrics in pharmaceutical companies or CRO companies (Job titles will be decided per applicant’s working experience)
- Have strong execution ability
- Strong independent scientific research ability, logical thinking, and coordination/problem-solving skills
- Have clear written and oral communication skills
- Have a good team spirit
- Demonstrated expertise in QSP and popPK modeling, including proficiency with tools such as NONMEM, R, MATLAB, Monolix, etc.
- Deep understanding of PK/PD principles, translational medicine, and the role of quantitative pharmacology and model-informed drug development (MIDD) in clinical trials and drug development.
- Demonstrated ability and experience in applying modelling and simulation approaches to enable rational and efficient preclinical and clinical drug development.
- Familiar with regulatory requirements and guidelines of clinical pharmacology.
- Good project management skills, and the ability to collaborate with other departments and manage with internal and external partners.
- Proven track record of scientific contributions through publications or presentations.
- Good personality, honest and trustworthy.
- Physically and mentally healthy, love life.
#Li-JR1
#Li-Contractor
#Li-Hybrid
Please note: These benefits are offered exclusively to permanent full-time employees. Contractors are not eligible for benefits through Legend Biotech.
EEO Statement
It is the policy of Legend Biotech to provide equal employment opportunities without regard to actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, related medical conditions and lactation), gender identity or gender expression (including transgender status), sexual orientation, marital status, military service and veteran status, disability, genetic information, or any other protected characteristic under applicable federal, state or local laws or ordinances.
Employment is at-will and may be terminated at any time with or without cause or notice by the employee or the company.
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Scientist I, Quantitative Systems Pharmacologist
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Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
We are seeking a QSP modeling & simulation scientist to be part of the Nonclinical Development and Clinical Pharmacology (NDCP) organization. This position will be responsible for developing, validating, and executing modeling projects with a focus on mechanistic PBPK-QSP mathematical models for small molecule programs to increase mechanistic understanding of compound PK behavior and drug distribution, pharmacological effects on RAS targets, support clinical translation, and drive future discovery and development efforts. As a Quantitative Systems Pharmacologist, you will:
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Develop, validate, execute, and refine quantitative systems pharmacology (QSP) models, minimal physiologically based pharmacokinetic (PBPK) models, semi-mechanistic PK/PD models, and tumor growth models to support development and discovery phase projects including next-generation inhibitor design and assessment of combination potential.
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Propose and perform in silico simulations to answer complex mechanistic questions, create data visualizations to effectively communicate modeling results to a wide-ranging audience, and devise strategies to improve model outputs.
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Survey the related literature to understand key physiological and biological processes, abstract the basic mechanistic elements, identify the relevant data, and summarize assumptions to be incorporated into existing or new PBPK-QSP models.
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Propose new mechanistic in vitro and in vivo experiments to test model assumptions and structure. Provide in silico support for preclinical translation including clinical efficacious doses/exposure projection, potential combination dosing regimens with other cancer therapeutics.
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Work collaboratively with other functions to build internal infrastructure supporting data transfer and quality control.
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Document contributions, including assumptions, mathematical models, data analyses, and data visualizations, to be shared with other scientists or used for archival purposes.
Required Skills, Experience and Education:
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A Ph.D. in a quantitative discipline (systems pharmacology, computational biology, engineering, mathematics, physics, etc.) and 0-2 years of industry experience is desired.
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Strong understanding of the principles and limitations of mathematical modeling, pharmacokinetic models, pharmacodynamic models, and quantitative systems pharmacology/biology models.
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Proficiency in mathematical and computational methods including ordinary differential equations (ODEs), nonlinear systems, statistics, optimization, and parameter inference.
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Proven record developing, calibrating, and validating dynamical system models in pharmacological and biological systems.
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Demonstrable hands-on experience with programming languages used in scientific computing, such as MATLAB, Python, Julia, and R.
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Capable of working proactively and independently to deliver high–quality modeling results in a timely manner.
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Able to effectively communicate modeling assumptions, limitations, and simulation results to non-specialist and specialist audiences.
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A critical thinker and team player who can work cross-functionally with others.
Preferred Skills:
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Experience with diverse dynamical system methods like ODE-based, PDE-based, nonlinear mixed effects, agent-based, Markov, Boolean, etc.
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Experience with integrating large data sets into QSP.
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Experience with agentic coding workflows such as Copilot, Cursor, Codex, and Claude Code.
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Experience with data-driven methods such as ML-based predictive regression models and physics-informed neural network models.
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Experience with modeling software such as SimBiology, NONMEM, Pheonix WinNonlin, Monolix, Simcyp designer, etc.
#LI-Hybrid #LI-CT1
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
Ready to apply?
Apply to Revolution Medicines
Senior Director, Clinical Pharmacology
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Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
We are seeking a passionate and experienced Clinical Pharmacologist with strong early development background to be part of the Nonclinical Development and Clinical Pharmacology (NDCP) Organization.
As a member of the Early Development Clinical Pharmacology group, you will:
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Provide strategic insight and technical leadership within the Clinical Pharmacology function.
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Author technical reports and/or regulatory documents for major milestones of clinical development, specifically IND, EOP1 & EOP2 Briefing Documents. Participate in regulatory interactions and responses to regulatory questions.
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Apply state-of-the-art quantitative modeling, including translational PK/PD, population PK, and exposure-response analyses, to guide recommended phase 2 dose/schedule (RP2Ds) selection for pivotal studies.
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Work with the Discovery organization to support assets in the IND-enabling stage, including collaboration with DMPK and Toxicology groups in assessment of human start dose and assessment of the need for human DDI studies.
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Work with the Clinical Development team in designing FIH study.
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Design and report Clin Pharm studies such as hADME, Food-Effect and DDI studies.
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Engage and work with CROs on clinical pharmacology activities.
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Represent the Clinical Pharmacology function in project teams and build strong working relationships with cross-functional teams to impact critical decisions.
Required Skills, Experience and Education:
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A Ph.D. or Pharm.D (with Fellowship) with Pharmaceutical Sciences background with 8-10 years of relevant industry experience in Clinical Pharmacology.
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Prior experience with small molecules oncology drug development.
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Familiar with FDA’s Project Optimus guidance.
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Well-informed in current and emerging standards of regulatory requirements and expectations for clinical pharmacology.
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Hands-on experience with WinNonlin and Clin Pharm study designs.
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Strong understanding of DMPK, CMC and Toxicology and related regulatory guidance is required.
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Excellent verbal and written communication skills, and ability to clearly convey complex concepts and findings to both non-specialist and specialist audiences.
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A critical thinker and passionate team player and quick learner with high energy who thrives in a dynamic and fast-paced environment.
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Prior management experience.
Preferred Skills:
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Prior experience interacting with FDA on dose optimization.
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Hand-on experience with PBPK models.
#LI-Remote #LI-CT1
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
Ready to apply?
Apply to Revolution Medicines
Associate Director, Clinical Pharmacology
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Revolution Medicines is a late-stage clinical oncology company developing novel targeted therapies for patients with RAS-addicted cancers. The company’s R&D pipeline comprises RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. The company’s RAS(ON) inhibitors daraxonrasib (RMC-6236), a RAS(ON) multi-selective inhibitor; elironrasib (RMC-6291), a RAS(ON) G12C-selective inhibitor; zoldonrasib (RMC-9805), a RAS(ON) G12D-selective inhibitor; and RMC-5127, a RAS(ON) G12V-selective inhibitor, are currently in clinical development. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity:
We are seeking a passionate and experienced Clinical Pharmacologist with strong early development background to be part of the Nonclinical Development and Clinical Pharmacology (NDCP) Organization.
As a member of the Early Development Clinical Pharmacology group, you will:
-
Provide strategic insight and technical leadership within the Clinical Pharmacology function.
-
Author technical reports and/or regulatory documents for major milestones of clinical development, specifically IND, EOP1 & EOP2 Briefing Documents. Participate in regulatory interactions and responses to regulatory questions.
-
Apply state-of-the-art quantitative modeling, including translational PK/PD, population PK, and exposure-response analyses, to guide recommended phase 2 dose/schedule (RP2Ds) selection for pivotal studies.
-
Work with the Discovery organization to support assets in the IND-enabling stage, including collaboration with DMPK and Toxicology groups in assessment of human start dose and assessment of the need for human DDI studies.
-
Work with the Clinical Development team in designing FIH study.
-
Design and report Clin Pharm studies such as hADME, Food-Effect and DDI studies.
-
Engage and work with CROs on clinical pharmacology activities.
-
Represent the Clinical Pharmacology function in project teams and build strong working relationships with cross-functional teams to impact critical decisions.
Required Skills, Experience and Education:
-
A Ph.D. or Pharm.D (with Fellowship) with Pharmaceutical Sciences background with 5+ years of relevant experience in Clinical Pharmacology.
-
Prior experience with small molecules oncology drug development.
-
Familiar with FDA’s Project Optimus guidance.
-
Well-informed in current and emerging standards of regulatory requirements and expectations for clinical pharmacology.
-
Hands-on experience with WinNonlin and Clin Pharm study designs.
-
Strong understanding of DMPK, CMC and Toxicology and related regulatory guidance is required.
-
Excellent verbal and written communication skills, and ability to clearly convey complex concepts and findings to both non-specialist and specialist audiences.
-
A critical thinker and passionate team player and quick learner with high energy who thrives in a dynamic and fast-paced environment.
-
Prior management experience.
Preferred Skills:
-
Prior experience interacting with FDA on dose optimization.
-
Hand-on experience with PBPK models. #LI-Hybrid #LI-CT1
The base pay salary range for this full-time position for candidates working onsite at our headquarters in Redwood City, CA is listed below. The range displayed on each job posting is intended to be the base pay salary range for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our base pay salary ranges are determined by role, level, and location. Individual base pay salary is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base pay salary range is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
We are aware of recent recruitment scams in which individuals or organizations falsely represent themselves as being affiliated with Revolution Medicines. These scams may appear as false job advertisements or unsolicited contacts through communication or chat platforms, email, phone, or text message.
Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address.
If you believe you’ve been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com so we can share these impersonations with our IT team for tracking and awareness.
Ready to apply?
Apply to Revolution Medicines
Vice President, Clinical Pharmacology
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Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).
Our mission is powered by our people. Our core values – be audacious, be curious, be authentic, be engaged, and be accountable – creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.
The Position
The Vice President of Clinical Pharmacology will provide leadership and support to the clinical pharmacology team and be accountable for the overall strategy for determining the PK, PD, and immunogenicity properties of all drugs and drug candidates in development and, as applicable, through commercialization. As the clinical pharmacology expert within the company, you have experience and expertise in matrixed leadership and team management, and will lead, develop, and educate through cross-functional teams. In addition, there will be opportunities to contribute to diligence assessments. Reporting directly to the SVP, Head of Clinical Development, you will have high visibility at leadership levels, including with the Chief Medical Officer. You can efficiently and effectively synthesize internal and external data to produce a clinical pharmacology strategy.
Responsibilities
- Serve as the clinical pharmacologist for the company across all clinical programs, providing strategic and scientific input from preclinical development through Phase 3 trials
- Lead the Clinical Pharmacology team accountability for the clinical pharmacology strategy for Amylyx' development portfolio from pre-IND through and post approval, including design and implementation of program specific clinical pharmacology studies, data analysis, internal decision points, and external regulatory interactions
- Integrate clinical pharmacology knowledge with a broad understanding of and collaboration with related disciplines such as clinical, statistics, regulatory, nonclinical ADME, toxicology to support and impact development decisions
- Ensure appropriate PK, PD and PK/PD data analyses (including population PK, PK/PD modeling and simulation) are conducted for each study/program.
- Collaborates with toxicologist and preclinical pharmacology scientists to design, analyze, interpret, and report preclinical PK and translational PK/PD studies to support candidate selection and IND filing, including human PK prediction to support starting dose and dose escalation schemes for first-in-human studies
- Ensure adherence to agreed timelines and budgets to insure prompt and accurate execution of deliverables from clinical pharmacology studies and programs
- Serves as the clinical Pharmacology expert across study and program teams
- Develops and implements new clinical pharmacology approaches to processes and clinical studies that impact development programs
- Contributes to program strategy, study design, protocol preparation, study execution, data review/analysis, study reports and regulatory document preparation
- Works closely with research and development teams and provides input into assay development, CRO selection and CRO management. Leads method development, method qualification, method validation activities as SME and sponsor monitor, as assigned.
- Represents nonclinical and clinical pharmacology during meetings and discussions with regulatory authorities
- Creates or guides nonclinical and clinical pharmacology summary documents
- Reviews literature and peer-reviewed publications to keep apprised of global regulatory developments in clinical pharmacology; Authors/ reviews manuscripts for submission to peer-reviewed journals
Required Qualifications
- PhD, PharmD, MD, or equivalent training in pharmacokinetics, pharmaceutical sciences, or related disciplines
- Minimum 12 years of experience within the pharmaceutical and biotechnology industry with 5+ years' direct experience in Clinical Pharmacology
- Experience in an array of molecules including biologics, small molecules and gene therapy
- Demonstrated experience in writing, presenting, and discussing clinical pharmacology with regulatory authorities as well as other external and internal stakeholders
- Strong analytical skills and ability to interpret complex clinical data sets as well as deep understanding of individual patient data coupled with excellent written and verbal communication skills
- Ability to work in cross-functional teams and manage multiple projects, engaging subject matter experts across functions to drive the execution of programs
- Strong technical proficiency in PK analysis (NCA and PopPK)
- Ability to work with an elevated level of integrity, accuracy, and attention to detail, while executing corporate objectives and goals
- Entrepreneurial, enjoys working in a fast-paced, small-company environment
Work Location and Conditions
- At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.
- You will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested.
- You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.
Compensation
The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.
To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn.
To return to our website please click here.
Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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Director, Supply Chain & External Manufacturing
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Position Summary:
We are seeking a Director of Supply Chain and External Manufacturing to join our CMC group at Tessera Therapeutics. This position will offer an exciting opportunity to build and manage the overall supply chain and external manufacturing function. We are searching for a driven, enthusiastic, and self-motivated individual who is comfortable multitasking and working independently on various aspects of the platform. This individual will join a dynamic, rapidly growing, and highly collaborative team.
You are interested in:
- Designing, building, and implementing phase appropriate supply chain and external manufacturing network strategies that ensure timely growth of capabilities and continuous supply of critical materials
- Driving the identification, contracting, relationship management, and performance of critical GMP supply chain and CMO partners
- Engaging in portfolio and program planning to ensure processes and capabilities are established to meet company needs and that critical materials are delivered on time
- Working collaboratively with Process Development, Manufacturing, Quality, Regulatory, Legal, Procurement, Finance, and other key stakeholders
- Establishing and leading cross-functional teams responsible for ensuring successful project execution with CMO partners
- Providing financial oversight and leading/supporting overall business improvement opportunities with External Parties
- Being responsible for supply chain and external manufacturing budgeting and providing strategic input into long-range planning processes
Your Experience Includes:
- BS in Engineering or Life Science Discipline with 15 years related experience or Masters with 13 years related experience or PhD with 10 years of related experience
- Proven leadership in all areas of Supply Chain and CMO relationship management
- Broad experience in supply chain processes, methodologies, and technologies
- Experience and ability to draft, revise, review, and negotiate complex CMO contract terms
- Strong financial acumen with experience managing budget and P&L
- Exceptional written and verbal communication skills
- Proven ability for strategic thinking in a complex business environment
Preferred Qualifications:
- Certifications in clinical supply chain management, project management
- Knowledge of gene therapy regulatory guidance
- Experience working in a gene therapy supply chain role or with gene therapy modalities
- Experience building clinical supply chain capabilities in US and EU
Meet your Manager:
All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.
Jacob Claridge – Senior Director, Technical Operations
Jacob Claridge currently serves as the Senior Director of Technical Operations at Tessera Therapeutics where he leads a multidisciplinary team responsible for building, implementing, and supporting GMP manufacturing operations to enable material supply for Tessera’s pipeline programs.
Prior to joining Tessera, Jacob previously held technical leadership roles at Astellas, Moderna, Momenta, and Regeneron where he had the opportunity to work with several drug modalities. He has a passion for translating complex scientific processes into scalable, reproducible operations and building out teams that enable this capability. Jacob holds an MBA from UC Berkeley and a BS in Bioengineering from Lehigh University.
Meet our Leadership Team and Board of Directors
Meet your Talent Partner:
Ben Hoogheem – Senior Director, Head of Talent Management
As Head of Talent Management at Tessera Therapeutics, Ben leads Tessera’s talent strategy across talent acquisition, performance management, and talent mobility.
Ben began his career as an in vivo Pharmacologist, which gave him a lasting appreciation for the rigor, creativity, and collaboration that drive scientific discovery. That foundation continues to shape how he helps build organizations designed to enable science thrive.
Ben is focused on aligning exceptional people with bold science – creating the structure, clarity, and culture that empower teams to scale effectively and achieve meaningful impact.
Compensation:
The stated base salary range represents Tessera’s good-faith estimate for this role. Actual compensation will be determined based on a number of factors, including but not limited to individual qualifications, years of relevant experience, internal compensation alignment, and external market data.
Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness, and financial security of our employees and their families. Benefits currently include group medical, vision, and dental coverage; group life and disability insurance; a 401(k) plan with company contribution; tuition reimbursement; and more.
This position is also eligible for an annual incentive bonus and equity grants as part of Tessera’s total rewards program.
Per Year Salary Range: $186,000 - $239,000 USD
Company Summary:
Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy.
More about Tessera Therapeutics:
Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com
Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.
Ready to apply?
Apply to Tessera Therapeutics