The Impact You’ll Make

As a key member of Recursion's partnership-facing data science team, you will be at the forefront of reimagining drug discovery from first principles using Recursion’s massive data and compute capabilities. As senior computational biologist, you will be supporting a portfolio of partnership preclinical drug programs and be responsible for designing and executing analyses to support target nomination, validation, and early programs in neuroscience diseases.

You will integrate layers of Recursion platform data (phenomics, transcriptomics, proteomics, etc) to validate the link between target and disease biology and to propose targets and early programs in novel areas of neuroscience. You will partner with biologists and medicinal chemists to build supporting data packets for targets from our phenomic maps, target screens, and partnered patient data sets. You will also collaborate with computational scientists from across the organization to develop, deploy, and scale novel approaches to: 1) translational validation in hit to lead, 2) mechanism-of-action identification/de-risking, and 3) build evidence for patient connectivity to match the targets we are validating and medicines we are creating to the patients who need them.  

In this role, you will:

• Deliver biological insights on therapeutic candidates and disease biology from the analysis of high-dimensional (phenomics, transcriptomics, proteomics, patient-derived) datasets that support clinical development planning
• Evaluate the biological and molecular evidence for therapeutic hypotheses and accelerate drug program progression into the clinic
• Synthesize diverse datasets (internal and external) to generate and evaluate hypotheses for drug discovery, biomarker development, mechanism of action and target population identification
• Present data analysis to decision makers and stakeholders in a clear and compelling way that drives toward getting medicines to patients
• Assess new data sources, develop and scale new analysis methods, and support key program decisions with the ultimate goal of bringing life-changing therapies to patients at unprecedented speed
• Industrialize analysis approaches to not only solve for the current project, but also to accelerate future projects and scale the impact that we can have
• Collaborate cross-functionally with Recursion’s data science, biology, medicinal chemistry, and  platform, teams to further advance Recursion’s ability to interpret and translate large-scale data assets into therapeutic programs

The Team You’ll Join 

Our group is a bold, agile, diverse collective of computational drug discovery scientists and data scientists deeply focused on the singular goal of bringing new therapeutics into the clinic at an accelerated pace. We are a computational group that spans precision oncology, neuroscience, and I&I (immunology and inflammation), and focuses on advancing novel, targeted therapies for these disease areas. We partner closely with our biologists and medicinal chemists to design and execute impactful and decisional data analysis for multiple programs. We are responsible for data strategy across the portfolio and supported by computational leadership in designing scalable and reproducible experiments that serve to advance multiple programs within the portfolio. 

Our team collaborates extensively with computational biologists in other therapeutic areas (immunology, oncology, etc.) as well as data scientists and engineers from our core platform teams to provide a strong network of feedback and support. 

The Experience You’ll Need

• PhD in a relevant field (computational biology, systems biology, bioinformatics, neuroscience, etc.) with a very strong computational focus and 5+ years of experience in biotech or pharma industry OR MS in a relevant field
• Experience applying computational methods (including probabilistic, statistical, and/or machine learning techniques) to analyze and integrate matched human clinical and molecular data in a high-level programming language such as Python or R
• Deep expertise in the analysis and data integration of one or more ‘omics data modalities (phenomics, transcriptomics, proteomics, genomics) and/or human clinical data
• Exceptional data visualization skills
• Excellent cross-functional communication skills, including an ability to explain complex scientific concepts to a variety of audiences using a combination of plots, documents, and presentations

Nice To Have:

• Strong understanding of patient genetics and historical druggability of disease-relevant pathways,  including experience working with patient data
• Experience in efficiently advancing drug programs from proof of concept and into clinical development
• Experience with neuroscience clinical trial biomarker analysis
• Experience working as part of partnerships or client facing (consulting) teams

Working Location & Compensation:

This is an office-based, hybrid role in either our Salt Lake City or New York City offices. Employees are expected to work in the office at least 50% of the time.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $200,600 to $253,100. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. 

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The Impact You’ll Make

As a computational biology specialist on our Target ID team, you will be at the forefront of transitioning Recursion to its next era of drug discovery. You will serve as a critical biological anchor for a highly technical data science team building the next generation of our target discovery pipelines.

The team’s mission is to identify novel therapeutic targets at scale across the genome for hundreds of indications. You will have access to all of Recursion's data layers—including massive internal maps, functional genomics, and rich patient data (transcriptomics, genetics, and Real-World Data/EHR)—and will be tasked with proposing, piloting, and deploying new methods to integrate these datasets.

Crucially, you will leverage your biological subject matter expertise to orient and focus your data scientist and software engineer peers towards reliable and correct usage of biological data and feasible candidate programs. As we build out semi-automated and agentic tools (e.g., multi-agent LLM systems for portfolio oversight and target assessment), your deep real-world biology experience will guide the development of these tools, ensuring they are grounded in biological reality and translate to meaningful portfolio and patient impact.

The ideal candidate is a computational biology specialist with high fluency in data science tech stacks. You know how to build and evaluate predictive models and build agentic pipelines, and your differentiator is your deep understanding of patient-relevant datasets, disease biology, and target discovery.

In this role, you will:

• Discover & Evaluate: Propose and validate novel targets using deep integration of patient data (transcriptomics, population genetics, EHR, etc) and Recursion's internal multi-omic data layers.
• Guide & Automate: Collaborate closely with data scientists to build, refine, and guide semi-automated and agentic target discovery tools. You will ensure these tools are biologically sound and can scale to evaluate hypotheses across many indications spanning a wide range of therapeutic areas.
• Triangulate: Use advanced statistical methods (e.g., causal inference, survival modeling) to establish confident target-to-patient connections and define specific addressable patient populations for early pipeline programs.
• Bridge the Gap: Translate complex platform findings into disease-relevant applications, bridging the gap between high-dimensional data science output and actionable drug discovery insights.
• Present & Influence: Communicate complex biological rationale and data analyses to decision-makers and cross-functional stakeholders, driving data-backed "go/no-go" decisions in a two-stage target approval process.

The Team You’ll Join

Our group is a bold, agile, diverse collective of data scientists and computational biologists driving Recursion’s early portfolio strategy. We are focused on aggressively expanding our early-stage pipeline with highly validated, novel therapeutic targets. To achieve this, we prioritize defining specific patient populations and establishing clear, data-backed translational paths from day one of every new program.

Because this team is dominated by experts in traditional data science, AI/ML, and software engineering, your role is absolutely critical. You will provide the essential biological experience and subject matter expertise to improve and accelerate the work of your peers. Essential attributes for this role include a bold, execution-first attitude, high technical fluency to collaborate seamlessly on data-science-heavy codebases, and a passion for deploying rigorous science to develop life-changing medicines.

The Experience You’ll Need

• PhD in Computational Biology, Bioinformatics, Human Genetics, Systems Biology, or a closely related field with 3+ years of experience in the biotech or pharma industry OR MS in a relevant field and 5+ years of industry experience focusing on target ID or early drug discovery.
• Biological SME: Deep, real-world experience in target discovery, functional genomics, and understanding the druggability of disease-relevant pathways.
• Data Science Fluency: Highly proficient in Python and/or R, with a strong ability to seamlessly integrate into a data-science-heavy tech stack. Comfortable with modern software engineering practices, cloud computing, and machine learning concepts.
• Patient Data Expertise: Extensive experience working with "discovery-related" human data, particularly transcriptomics (bulk/single-cell), patient genetics/GWAS, and clinical/real-world data (e.g., EHR).
• Analytical Rigor: Experience applying advanced computational and statistical methods to establish biological causality (e.g., survival analysis, causal inference modeling).
• Excellent cross-functional communication skills, with a proven track record of upskilling peers in biological concepts and guiding technical teams toward translatable biological outcomes.

Nice To Have:

• Experience working with, prompting, or integrating Large Language Models (LLMs) and autonomous agentic workflows into scientific research.
• Familiarity with building or utilizing Knowledge Graphs for target identification.
• Experience working in the field of oncology or immunology.

Working Location & Compensation:

This is an office-based, hybrid position at our US headquarters located in Salt Lake City, Utah. Employees are expected to work in the office at least 50% of the time.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $230,000. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. 

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