Legend Biotech is seeking a Director, Thought Leader Liaison & Strategic Alliances, Northeast as part of the Commercial team based in Somerset, NJ.

Role Overview

The Director, Thought Leader Liaison (TLL) is a senior individual contributor responsible for shaping and advancing the organization’s thought leader engagement strategy across the cell therapy landscape. This role operates at an enterprise level, cultivating high-impact relationships with national and regional experts to inform strategy, accelerate adoption, and elevate the organization’s scientific and clinical presence.
Unlike the Associate Director TLL role, which is primarily focused on execution within a defined scope, the Director TLL role is distinguished by breadth of influence, strategic insight generation, and executive-level engagement. The Director TLL serves as a trusted scientific partner to external experts and an internal advisor to senior leadership—translating complex field insights into actionable enterprise strategy.

Key Responsibilities

Strategic Thought Leader Engagement

• Lead relationships with top-tier national and regional thought leaders in cell therapy, oncology, and transplant.
  
• Design and execute long-term engagement strategies aligned to enterprise priorities and lifecycle needs.
  
• Serve as a credible scientific partner in discussions spanning clinical practice, research trends, operational challenges, and future innovation.
  

Enterprise-Level Insight Generation

• Synthesize insights across engagements to identify emerging trends, unmet needs, and strategic opportunities.
  
• Translate field insights into clear, executive-ready narratives that inform strategy, messaging, evidence generation, and education.
  
• Proactively identify gaps between internal strategy and external reality, elevating recommendations to leadership.
  

Executive & Cross-Functional Partnership

• Act as a strategic advisor to Medical Affairs, Clinical Development, Commercial, Marketing, Market Access, and Clinical Education.
  
• Support executive-level meetings, advisory boards, and strategic initiatives requiring deep scientific and field expertise.
  
• Influence internal decision-making without direct authority through credibility, data, and perspective.
  

Scientific Credibility & External Presence

• Represent the organization with a high level of scientific rigor and professionalism in external forums.
  
• Contribute to the shaping of advisory boards, peer-to-peer forums, and scientific exchange models.
  
• Ensure compliant, balanced, and ethical engagement with thought leaders at all times.
  

Standards Setting & Capability Elevation (Non-Managerial)

• Serve as a role model for advanced TLL capabilities, including insight quality, engagement depth, and strategic thinking.
  
• Contribute to the evolution of insight frameworks, engagement models, and performance standards.
  
• Provide informal mentoring and best-practice sharing across the TLL team without direct supervisory responsibility.
  

Requirements

• Minimum: Bachelor’s Degree from accredited college or university.
• Advanced degree also considered.
• Minimum of a bachelor’s degree in a related field required; MD, PharmD, PhD or other related graduate degree preferred.
  
• 10-15 years of pharmaceutical or biologics industry experience in sales, marketing, key account management, or medical engaging with thought leaders or influential HCPs required.
  
• 4 years of relevant Multiple Myeloma, Cell Therapy, or Oncology experience required.
  
• Deep expertise in oncology, cell therapy, transplant, or related therapeutic areas.
  
• Demonstrated success influencing senior internal and external stakeholders.
  
• Proven ability to translate complex scientific dialogue into actionable strategic insight.
  
• Able to work cross-functionally with internal and external stakeholders to innovate, collaborate, and deliver results.
  
• Valid driver's license.
  
• Ability to travel 75 – 85%.
  
• Required to exercise sound judgment and discretion, independently assess and resolve complex situations and shift priorities as the need arises.
  
• Possess excellent oral and written communication skills.
  
• Able to coordinate multiple projects with overlapping deadlines and complete tasks autonomously.
• Challenges the status quo, looks for/adopts best practices, embraces change.
  
• Must demonstrate flexibility, while maintaining a sense of urgency.
• Demonstrated ability to access and understand challenges and educational needs of stakeholders and accounts within the assigned geography.
  
• Proven customer focus.
  
• Demonstration of strong in-person and virtual presentation and engagement skills.
  
• Superior clinical skills and business acumen with the proven ability to excel in a technically complex and ambiguous environment.
  
• Experience working with CAR-T or other cell and gene therapies.
  
• Proven track record of shaping strategy through field-derived insights.
  
• Demonstrated ability to identify critical activities and tasks and adjusts priorities to meet organizational goals and objectives.
  
• Demonstrated ability to read situations quickly, anticipate and adjust for problems and roadblocks.
  
• Proficient in Microsoft Office (Word, Excel, Outlook, PowerPoint).

#Li-JK1

#Li-Hybrid

Legend Biotech is seeking an Executive Director, Pipeline Clinical Lead as part of the Clinical Development team based in Somerset, NJ.

Role Overview

The Pipeline Clinical Lead is a senior clinical development leader accountable for the scientific and medical direction of early stage clinical programs. This role provides strategic and operational leadership across first in human through proof of concept studies, with accountability for clinical strategy, trial design, execution, interpretation, and regulatory interactions.

The Pipeline Clinical Lead will lead and develop a team of physicians and scientists, work closely with cross functional partners, and collaborate with external development partners and investigators. Deep expertise in clinical trial design, regulatory frameworks, and compliance in drug development—ideally within cell therapy—is essential.

This role requires strong scientific judgment, leadership presence, and a hands on approach in a fast paced, entrepreneurial environment, with a clear focus on patient safety and clinical impact.

Key Responsibilities

Clinical Development Leadership

• Serve as clinical science lead for early stage programs (pre IND through Phase 1/2), including study design, execution, data interpretation, and reporting.
• Define and integrate clinical strategies, including PK/PD, biomarkers, diagnostics, and translational approaches, particularly for cell and gene therapies.
• Provide clinical input into asset selection, review of preclinical data, and development path decisions.

Regulatory & Compliance

• Lead or support IND preparation and amendments, clinical sections of regulatory submissions, and responses to health authority questions.
• Represent the clinical function in pre IND, IND, and (as applicable) BLA/MAA interactions with regulatory agencies.
• Champion patient safety, ethical conduct, and compliance with GCP, corporate policies, and global healthcare regulations.

Cross Functional & External Collaboration

• Partner closely with Clinical Operations, Biostatistics, Regulatory Affairs, Early Discovery,
• Manufacturing, Biomarkers, and Pharmacovigilance to ensure integrated program delivery.
• Collaborate with external development partners, academic investigators, KOLs, and study sites.
• Act as a credible scientific and clinical representative for programs in internal governance and external forums.

People & Matrix Leadership

• Provide direct line management and mentorship for Medical Directors, Clinical Research Scientists, Medical Writing, Clinical Program management and other clinical staff as applicable.
• Lead effectively in a matrix environment, anticipating cross functional needs and proactively resolving conflicts or risks.
• Contribute clinical leadership to business development, due diligence, and partnership activities when required.

Requirements

• MD or MD PhD (or equivalent) with US board certification or international equivalent.
• ≥8 years of clinical development experience in industry and/or academia, with demonstrated leadership in hematology/oncology.
• Proven experience designing and executing clinical trials from first in human through registrational stages.
• Prior involvement with IND submissions; experience with BLA/MAA filings and health authority meetings strongly preferred.
• Cell therapy and/or CAR T clinical development experience highly desirable IT Skills.
• Strong scientific judgment with the ability to navigate complex clinical and regulatory challenges.
• Demonstrated ability to lead cross functional and geographically distributed teams in a matrix environment.
• Excellent written and oral communication skills, including protocol writing, regulatory documents, publications, and senior level presentations.
• Highly collaborative, influential leader with the ability to represent programs with credibility and confidence.
• Hands on, execution oriented mindset with strong organizational and analytical skills.
• Willingness to travel up to 15–20%.

#Li-AS1

#Li-Hybrid

Legend Biotech is seeking a Senior Manager, Internal Controls & Sustainability Reporting as part of the Finance team based in Bridgewater, NJ.

Role Overview

The Senior Manager, Internal Controls & Sustainability Reporting is responsible for executing the design, implementation, evaluation, and continuous improvement of the company’s internal control framework across financial reporting and select non‑financial reporting processes. This role plays a critical leadership position in ensuring compliance with SOX (404), managing enterprise-wide control assessments, partnering with business and IT leaders, and serving as a key liaison with Internal Audit and external auditors.
This role is critical to maintaining the integrity of the company’s reporting and supporting growth through strong governance and risk management. The Senior Manager, Internal Controls & Sustainability Reporting will also support the development and enhancement of sustainability reporting, and will have high visibility with finance leadership and the opportunity to meaningfully shape the internal control environment.
Prior experience with sustainability or ESG reporting is not required

Key Responsibilities

SOX & Internal Controls Leadership

• Drive the company’s SOX 404 compliance program end to end, including scoping, risk assessment, control design, testing strategy, remediation, and certification support.
• Evaluate the effectiveness of entity-level, process-level, and IT general controls (ITGCs).
• Support management’s assessment of internal controls over financial reporting (ICFR) and support quarterly and annual certifications.

Risk Assessment & Control Design

• Partner with process owners to identify financial reporting risks and design efficient, scalable controls.
• Assist in the standardization and optimization of controls, reducing redundancy while maintaining compliance.
• Assess the impact of new accounting standards, system implementations, acquisitions, and process changes on internal controls.

Audit & Stakeholder Management

• Coordinate walkthroughs, testing, issue resolution, and audit deliverables, proactively managing timelines and risks to prevent delays.
• Support the remediation of control deficiencies, including significant deficiencies and material weaknesses.
• Track control deficiencies, lead root cause analysis, and oversee remediation efforts through closure.

Process Improvement & Governance

• Support continuous improvement initiatives, including automation and use of governance, risk, and compliance (GRC) tools.
• Support broader GRC initiatives as needed.
• Assist with special projects for the Controller or CFO, including M&A integration and transformation initiatives.

Operational Audits

• Track and drive closure of operational audit deficiencies impacting the finance function, including follow‑up and remediation oversight.
• Collaborate with operational managers to design and implement effective controls to mitigate identified deficiencies.
• Modify policies, procedures, and internal control documentation to reflect corrected processes.
• If necessary, provide training to staff on updated processes and strengthen the overall control culture.

Sustainability Reporting (expected to be 25-50% of role)

• Support sustainability reporting processes aligned with global regulatory frameworks to promote accuracy, completeness, and assurance readiness.
• Assist with the development and maintenance of internal control frameworks over sustainability data.

Requirements

• Bachelor’s degree in Accounting, Finance, or related field.
• 7+ years of progressive experience in internal controls, SOX, public accounting, or a combination thereof. Big 4 or national public accounting firm experience a plus.
• Strong knowledge of COSO framework and exposure to IT general controls and automated control environments.
• Exposure to automation, data analytics, and/or AI‑enabled tools is a plus.
• ESG or Sustainability reporting experience preferred, not essential.
• CPA a plus.
• Knowledge of IFRS a plus.

#Li-LB1

#Li-Hybrid

Legend Biotech is seeking a Director, Accounting Operations as part of the Finance team based in Bridgewater, NJ.

Role Overview

The Director of Accounting Operations is primary responsible for managing the accounting operations for the US entity, overseeing the Accounts Payable and expense reimbursement processes, and leading key accounting systems and master data governance. This role is a key leader within Controllership, ensuring compliance with IFRS and internal policies. This leader will drive continuous improvement in our close cycle, reporting processes, accounting systems, and internal controls, while partnering cross‑functionally to support business growth and transformation. This role, reporting to the Corporate Controller, will work closely with the Consolidations & External Reporting, Treasury, IT, and FP&A functions.  

Key Responsibilities

• Own month end accounting and reporting responsibilities for US entities including but not limited to reviewing journal entries, variance analysis, and creation of operating entity reporting packages with timely submission into the financial reporting team in compliance with the quarter-end reporting calendar.
• Responsible for overseeing the accounting for right of use assets, payroll, fixed assets, prepaids, accruals, and collaboration accounting involving payable, advanced funding and milestone payments. Accountable to ensure all accounts are properly reported and supported.
• Oversee the Accounts Payable team to ensure timely processing, recording, and disbursement of third-party and I/C invoice payments.
• Prepare quarterly balance sheet and income statement analytics for the US operating entity.
• Prepare balance sheet account reconciliations and other SOX 404 controls on a timely basis.
• Oversee the administration of the Company’s cloud-based lease platform.
• Responsible for ensuring integrity of the general ledger, maintaining the chart of accounts and clearly defined mapping between ERP & Consolidations platforms.
• Assist Financial Reporting with ensuring Legend accounting policies are current and incorporate new industry technical accounting guidance and reflect changes in Legend’s accounting process.
• Partner with IT and drive successful implementations of incremental SAP modules (WBS, Treasury module, AP modules).
• Oversee the administration of the company’s T&E platform (Concur), expense reimbursement and ensuring company-wide compliance of the Company’s T&E policy.
• Drive automation and potential AI capabilities in the company’s PTP & R2R processes. Develop, implement and manage dashboard to drive performance of key accounting operations KPI’s.
• Cooperate with external auditors, timely deliver the financial information to third-parties and regulators when necessary.

Requirements

• Bachelor’s degree or above in accounting.
• CPA strongly preferred.
• 10+ years of combined experience in public accounting or an accounting operations role at a publicly traded company.
• Strong leadership skills with experience managing team, including both on-site and offshore employees.
• Experience in Business Process automation, Outsourcing and shared service deployment a plus.
• Experience in the biopharmaceutical and/or medical devices industry preferred.
• SAP S/4 experience a plus.

#Li-LB1

#Li-Hybrid

Legend Biotech is seeking a Sr. Master Data Governance Specialist as part of the Technical Operations team based in Raritan, NJ. 

Role Overview

We are actively seeking a proficient Sr. Master Data Governance Specialist with a specific focus on SAP Extended Warehouse Management (EWM) master data and materials orchestration throughout the End-to-End Manufacturing & Supply lifecycle. This role is pivotal in leading the design and execution of the Global Manufacturing & Supply (GMS) data governance process, from material creation to consumption across Warehouse, Materials Planning, Work Centers, Bill of Materials / Recipes, Costing and Quality Inspection attributes. This role will partner with the IT team and collaborate in the design-implementation of Legend's Master Data Management program. We are looking for a well-organized and process-oriented leader, with strong understanding of Manufacturing & Supply Chain Management operations, who can translate operational and technical data requirements into actionable programs and activities supporting execution of SAP day-to-day production processes.

The ideal candidate has expertise in developing and implementing data process workflows, identification / segmentation of core manufacturing and material data objects, and expertise in deployment of SAP MDG, especially EWM master data and inclusive but not limited to MM, SD, FI, etc., particularly within the biotech industry. As the functional GMS Data Specialist, you will play a vital role in executing and overseeing the BUILD and RUN operational aspects of SAP data creation within Legend's Manufacturing network.

Your role will involve collaborating with cross-functional business teams, IT and SAP Integration partners to define and optimize business processes, create data migration/conversion activities, and ensure adherence to regulatory requirements, including SoX, and CFR Part 21 and GxP as applicable. By driving the successful delivery of SAP solutions, you will contribute to the seamless operation of critical data processes within Legend Biotech.

Key Responsibilities

• Your primary role will be to design, implement, and deploy a global standard and data creation workflow process that supports GMS business activities, and in line with IT's MDG template.
• Utilize your extensive master data expertise to demonstrate a profound understanding of SAP EWM master data and configuration elements, MDG Materials, BOM, Recipes, MRP, MPS, Work Centers, Batch Management, Quality Inspection, Costing, among others.
• Collaborate with business stakeholders, collaboration partners, and business process owners to conduct comprehensive analysis on all GMS material management aspects addressing data creation, data quality, governance needs and dealing with all data interconnectivity with other systems.
• Build and drive plans to improve data practices for operational, reporting and analysis needs – Inclusive of development of processes, control, and best business practices around data management.
• Build organization understanding of data lifecycles from creation to end use, working with subject matter experts in various business functions, operations, and IT teams.
• Create and maintain process maps, data objects, and user guides, to ensure a comprehensive knowledge base.
• Manage and support all site-specific projects with respect to new product launches, alternate material sources, alternate BOM/recipes, etc. and collaborate on required change control deliverables where applicable.
• Provide expert-level support for SAP MDG modules, addressing functional issues, incidents, and change requests. Work closely with the support team to prioritize and resolve tickets efficiently.
• Oversee change management procedures, including business engagement, impact analysis, documentation review and approval, user testing reviews, and ensure smooth and controlled changes to minimize risks and disruptions associated with GMS activities.
• Identify opportunities for process improvement and optimization within the MDG areas, leveraging SAP functionalities and best practices to drive efficiency and effectiveness while maintaining regulatory compliance.
• Embrace and promote Agile principles and values within the team and projects, fostering a culture of continuous improvement and iterative development.
• Create an environment that encourages open communication, teamwork, and innovation, contributing to a positive and collaborative work culture.

Requirements

• Minimum of 5 years' experience in SAP MDG - Material Master, Planning, Procurement, Vendors Data Objects, Customer, Vendor, etc.
• Minimum of +3 years developing and implementing MDM solutions and data governance processes, including hands-on design and configuration
• Experience with leading business process reengineering and business process assessment.
• Exceptional communication and interpersonal skills, with the aptitude to effectively engage and influence stakeholders at all levels.
• Demonstrated capability to lead and manage cross-functional teams, fostering collaboration, and achieving high-performance outcomes; demonstrated ability to lead and manage change initiatives while driving organizational transformation.
• Advanced technical knowledge of SAP EWM Master Data specifically and in at least two (2) of the Production, Materials Management, and/or Quality modules

This position is designed as a hybrid role; however, we are also open to considering fully remote candidates.

#Li-RP1
#Li-Hybrid

Legend Biotech is seeking a Preclinical Scientist as part of the Research and Early Development team based in Somerset, NJ.

Role Overview

This position will perform preclinical IND-enabling pharmacology and toxicology studies to support pipeline programs. The ideal candidate will have experience in immunology or immune-oncology to assist preclinical cell therapy studies from discovery to first-in-human trials, and through marketing authorization. Furthermore, the successful candidate will work in a collaborative environment , and would be skillful in driving multiple projects by contributing to the development of cell-based immunotherapies.

Key Responsibilities

• Develop and validate assays to support diverse projects from lead optimization to the conduct of preclinical pharmacology and toxicology studies for regulatory submission. This includes, designing, optimizing, and implementing IND-enabling studies, contributing to the creation, review, and approval of prospective standard operating procedures, executing in vitro and in vivo IND-enabling studies, recording all experiments in an electronic laboratory notebook, reporting any deviations, analyzing and reporting processed data in the form of a study report.
• Design and support in vitro IND-enabling studies to assess efficacy and safety of cell therapies. 
• Support the preparation of scientific and regulatory documents of IND-enabling preclinical studies.
• The Preclinical Scientist will work independently reporting directly to the Director of Preclinical Pharmacology and Toxicology.
• The Preclinical Scientist will demonstrate competency and professionalism especially as it pertains to using the scientific method to design, execute, and troubleshoot in vitro laboratory experiments.

Requirements

• BS plus 5 years of experience, MS plus 3 years of experience.
• Work experience in immunology, cancer biology or related fields.
  
• Knowledge and expertise in immune-oncology of large molecules or cell therapy is a plus.
  
• Strong scientific background with hands on experience in cellular and molecular biology techniques (e.g., flow cytometry, ELISA, cell culture and cytotoxicity assays, qPCR, Western Blot and others).
  
• Demonstrated track record of scientific contributions in peer-reviewed journals and symposia.
  
• Ability to manage multiple programs in parallel while delivering on key milestones.
  
• Knowledge of GLP and regulatory agencies is a plus.
  
• Ability to multi-task in a fast-paced, highly collaborative diverse team environment.

#Li-JR1

#Li-Onsite

Legend Biotech is seeking a Program Lead, Cell and Gene Therapy as part of the Global Manufacturing and Supply team based in Raritan, NJ.

Role Overview

The program Lead will be responsible for developing and executing the internal commercial manufacturing strategy for iLVV (in vivo Lentiviral Vector). This role will lead strategic planning, drive execution, propose options to senior leadership, of the commercial manufacturing introduction activities across late-stage and commercial programs, ensuring technical excellence, regulatory readiness, operational execution, and seamless cross-functional alignment. The position requires close collaboration with cross-functional teams including R&D, process development, MSAT, global facility & engineering, Quality, procurement, regulatory affairs, and finance.

Key Responsibilities

Strategic Leadership

• Define and drive the internal commercial manufacturing strategy for iLVV.
• Evaluate internal/external options for iLVV commercial manufacturing, and seek stakeholder feedback.
• Present options and recommendations to senior leadership for decision-making.
• Provide clear, concise, and timely updates to senior management regarding program progress, risks, and strategic considerations.
• Motivate and inspire cross-functional teams, building momentum, alignment, and ownership.
• Make decisive, data-driven, and sometimes tough decisions to advance program objectives under aggressive timelines.

Planning & Execution:

• Develop detailed business and implementation plans and timeline for late stage clinical and commercial manufacturing to deliver launch milestones.
• Oversee facility fitness and readiness and ensure alignment with stakeholders on commercial tech transfer and production timelines.

Cross-Functional Collaboration

• Partner with R&D for process development and technology transfer.
• Work closely with engineering and Somerset facility teams for infrastructure planning.
• Drive decision-making that balances scientific rigor, speed, risk, and business impact.
• Coordinate with regulatory and quality teams to ensure compliance with global standards.
• Collaborate with finance to manage budgets and cost projections.

Process Development & Transfer

• Working with MSAT to drive commercial process transfer activities from development to manufacturing.
• Coordinate generation of process descriptions, control strategies, equipment requirements and Bill of Materials.
• Drive establishment of raw material requirements, QC method readiness and facility fit.
• Ensure robust scale-up and validation of vector manufacturing processes.

Manufacturing Site & Operational Readiness

• Ensure manufacturing facilities are prepared for the new product including capacity, equipment, utilities, and staffing.
• Partner with Supply Chain to secure long-lead materials, single-use components, and critical suppliers.
• Oversee line-of-business readiness: QA, QC, MSAT, warehouse, digital systems, labeling, analytics.
• Align on operational procedures (SOP updates, batch records, deviations/corrective actions).

Quality and Compliance

• Ensure compliance with applicable global GMP, ICH, and regulatory expectations.
• Support CMC submissions, PPQ documentation, change controls, and validation packages.
• Collaborate with Quality to ensure inspection readiness and audit support.

Continuous Improvement & Lifecycle Management

• Identify opportunities to optimize manufacturing robustness, cost, and yield post-launch.
• Implement lessons learned, knowledge management systems, and NPI best practices.
• Support product lifecycle changes such as process improvements, site expansions, and supply chain enhancements.

Requirements

Education

BS is required, Ph.D. preferred in Biotechnology, Biochemical Engineering, or related field.

Experience

• Minimum 10+ years in biopharmaceutical manufacturing. Viral vector late processes development/manufacturing experience is required.
• Proven experience in facility scale and layout planning, and commercial process transfer and validation.
• Strong understanding of cGMP requirements and regulatory frameworks for cell and gene therapy products.

Skills

• Strategic thinking and ability to build consensus among peers and influence senior leadership.
• Excellent project management and cross-functional leadership skills.
• Strong communication and stakeholder management capabilities.
• Ability to thrive in a fast-paced, evolving environment.
• Highly goal-oriented, ownership-driven, and laser-focused on execution.
• Comfortable navigating ambiguity and making quick, high-impact decisions.

#Li-BZ1

#Li-Hybrid

Legend Biotech is seeking a Project Manager, External Engagement (Contractor) as part of the Commercial team based in Bridgewater, NJ.

Role Overview

Reporting to Executive Director, External Engagement, the Project Manager will run and manage multiple projects in a proactive manner. Leverage project management tools and processes, including detailed timelines, milestones and daily tracking to ensure projects are delivered to company goals and commitments. Be prepared to report on project progress and status through weekly reporting or at the request of Leadership.

Key Responsibilities

• Define scope, goals, and deliverables of each assigned project that support business goals in collaboration with senior management and stakeholders.
• Develop full-scale project plans and associated communications documents.
• Identify and anticipate potential risks and establish plans to proactively address such potential risks.
• Effectively and proactively communicate project modifications to the impacted parties with explanations of new responsibilities, deadlines, target dates, etc.
• Coordinate with members of the Legal, Compliance, and Medical Affairs departments to ensure concurrence with budgetary, and other legal and compliance requirements.
• Develop and implement procedures, as needed, for project monitoring to include team meetings, action item follow-up, meeting minutes, and identifying new actions and resolutions.
• Coordinate with internal resources to assist with project management and execution.
• Manage workflow requirements and documentation related to the projects.
• Interface with executives/department leads for strategy and budgeting purposes.
• Efficiently manage and maintain a system of problem resolution (i.e., change in project requirements, missed deadlines, etc.). Facilitate resolution of project conflicts by consulting with project teams and stakeholders and developing innovative solutions.
• Weekly Reporting.

Requirements

• Bachelor’s Degree from accredited college or university.
• Two to four years project management experience, or combination of education and experience.
• Two + years’ experience in the pharma/biotechnology industry.
• Initiative-taker.
• Excellent people skills with the ability to lead, engage in focused and clear interactions with stakeholders from a variety of levels, functions, and companies.
• Strong familiarity with project management software, such as Microsoft Project
• Exceptional planning, organization, and execution skills.
• Strong quantitative and analytical skills.
• Demonstrated ability to identify, prioritize, provide resolution options, and escalate critical issues to Executive Leadership, as necessary.
• Demonstrated ability to manage timelines.
• Ability to anticipate and solve problems while analyzing complex issues and environments.
• Demonstrated excellence in project management, while effectively managing multiple projects/priorities.
• Strong oral and written communication skills and an ability to communicate complex concepts in a concise, simplified manner.
• Demonstrated ability to work with and coordinate demands from multiple internal and external stakeholders.
• Ability to effectively prioritize and execute in a high-pressure, milestone-driven, and rapidly changing environment is crucial.
• Exhibition of the highest degree of ethical standards and trustworthiness.

#Li-JK1

#Li-Hybrid

#Contract

Legend Biotech is seeking an Operations Supervisor as part of the Technical Operations team based in Raritan, NJ.

Role Overview

The CAR-T Operations Supervisor is an exempt level position working within Technical Operations team, responsible for directing the daily production of a personalized cell therapy to support both clinical and commercial requirements in a sterile cGMP environment. Job duties will be performed within a team-based environment, on an assigned production shift schedule.

Shift Options Available:

• Wed–Sat, 2nd Shift

Key Responsibilities

• Lead and supervise multiple units within the CAR-T process operations (i.e. component preparation manufacturing, MFG support operations, Mock cell, and CAR-T process) according to standard operating procedures and batch records and ensure safe and compliant manufacturing operations according to cGMP requirements.
• Lead the daily start of shift operations meetings, the daily wrap up production meetings and assign individuals their daily production task to execute and ensure compliance and successful completion of work-related tasks.
• Work closely with operations personnel on the production floor to provide guidance and perform production tasks as needed to help the team, in a manner consistent with safety policies, quality systems, and cGMP requirements.
• Support manufacturing investigations, create/revise operational procedures, including manufacturing work instructions, master batch records, forms, and support and manage change controls.
• Work closely with Operations Manager to help oversee the development of production personnel, provide input on personnel performance.
• Build strong partnerships with Manufacturing, Engineering, and Quality to ensure seamless execution of daily production tasks and work as part of a cross-functional team to address production issues as the first point of contact for operators on the production floor.
• Support the development of manufacturing processes, participate in various department projects, and will work with others to drive continuous improvements and efficiencies within cell therapy Technical Operations.
• Job duties performed routinely require exposure to and handling of biological materials and hazardous chemicals.
• Distance visual acuity of at least 20/40 (Snellen) in both eyes without corrective lenses or visual acuity corrected to 20/40 (Snellen) or better with corrective lenses.
• Color Perception both eyes 5 slides out of 8. 

Requirements

• Bachelor’s degree in Science, Engineering or related field or equivalent experience required.
• A minimum of 6 years of operations experience within a cGMP environment in the biotech/biopharma industry. Prior experience in manufacturing, quality, or engineering is required.
• Excellent communication and organizational behaviors skills are required.
• Proficiency with Microsoft Office tools (Word, Excel, PowerPoint, and Outlook) is required.
• Availability to work in a day shift (1st or 2nd shift) is required.
• Knowledge of cGMP regulations and FDA guidance related to manufacturing of cell-based products, and cleanroom behaviors.
• Must exhibit strong Leadership skills and ability to effectively communicate and influence Operations associate and convey information to Management.
• Ability to work independently and successfully, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively.
• Must be able to manage shifting priorities to meet critical deadlines in a fast paced and dynamic, growing environment, while providing clear direction to team members.
• Strong analytical, problem solving and critical thinking skills and the ability to lead as a change agent to promote flexibility, creativity, and accountability.
• An ability to build strong partnerships and effectively integrate with external collaborators to drive projects/programs forward in a matrixed environment.
• Clear and succinct verbal and written communication skills with an attention to detail and the ability to follow procedures.
• Experience with Operational Excellence and/or Lean Manufacturing is an asset.
• Ability to accommodate shift work including evenings and weekends as required by the process.
• Ability to accommodate unplanned overtime on little to no prior notice.
• Sufficient vision and hearing capability to work in job environment with physical dexterity sufficient to use computers and document production records
• A working leader who can participate in production runs in critical situations when needed.
• Ability to lift a minimum of 25 lbs. and stand for a long period of time. 

#Li-RN1

#Li-Onsite

Legend Biotech is seeking participants for Legend's Manufacturing Management, Leadership Development Program as part of the Technical Operations team based in Raritan, NJ.

Role Overview

The Early Career Leadership Program at Legend Biotech is a strategic, enterprise-focused development experience designed to accelerate the growth of high-potential professionals early in their careers. Rooted in our commitment to cultivating enterprise-minded, value-driven leaders, this program provides structured rotational exposure, executive mentorship, and real-time business impact across scientific, operational, and corporate functions.

Legend’s U.S. manufacturing network supports clinical trials and commercial CAR-T therapies for patients across the United States, with CARVYKTI® available at more than 140 treatment centers nationwide. Through our collaboration with Johnson & Johnson, we continue to expand manufacturing capabilities across both regions to meet growing patient demand. top

Join us in redefining what’s possible and build a career where your growth and patient impact go hand in hand

Key Responsibilities

• The Manufacturing Hi-Po Leadership Development Program at Legend Biotech is a 2.5–3 year leadership accelerator designed for high-potential Master’s graduates seeking to build careers at the intersection of advanced therapy manufacturing, operational strategy, and global supply.
• Participants will complete multiple-functional rotations (12 months each) within areas of Global Manufacturing; including Manufacturing Science & Technology (MSAT), Quality, Manufacturing, or Supply Chain over the course of the program. Rotations are tailored based on individual development goals, business needs, and participant interests, allowing candidates to gain targeted experience across key operational functions.
• This structured program integrates high-impact operations experiences, executive mentorship, and a Leadership Development Series focused on developing leaders at every level — from leading self and others to influencing senior stakeholders and driving enterprise-wide business outcomes.
• At Legend Biotech, we believe our people are our greatest asset. This program reflects our unwavering commitment to professional development, career mobility, and long-term leadership growth; empowering early-career talent to take on meaningful challenges, expand their impact, and shape the future of our organization.

Requirements

• Recent M.S or M.A Graduate (Class of 2023-2026)
• 2-3 years of professional experience in life sciences, manufacturing, engineering, or supply chain environments
• Strong analytical, problem-solving, and cross-functional collaboration skills.
• Demonstrated leadership potential and aspiration to grow into future operational and enterprise leadership roles.
• Degree in Biomedical Engineering, Supply Chain/Manufacturing, or related discipline.

#Li-CC1

#Li-Onsite

Legend Biotech is seeking a Manager, Site Contracts & Payments Management as part of the Clinical Operations team based in Somerset, NJ.

Role Overview

The Site Contracts & Payments Manager is responsible for site contracting and investigator payment process oversight and management, and vendor due diligence across Legend pipeline studies. The role serves as a central point of accountability for improving operational effectiveness, financial discipline, and sponsor-CRO-site workflow alignment for site contracting and payment processes.

Key Responsibilities

• Partner with CROs to develop and oversee process workflows, and create visibility into site contract and investigator payment workflow efficiency across studies.
• Partner with CROs, AP, Procurement, Finance, Legal, and study teams to align process workflows, identify gaps, and improve efficiency in contracting and payment execution.
• Monitor key milestones, bottlenecks, and escalations affecting site startup experience for contracting, payment timeliness, and financial predictability.
• Support reconciliation, issue resolution, and continuous improvement related to site contracting and investigator payment operations.
• Coordinate vendor due diligence and risk assessment activities with Procurement, Finance, QA, and other stakeholders.
• Performs other duties as required.

Requirements

• Minimum degree requirements of a bachelor’s degree (BA, BS) in scientific, health care, business, or related discipline. Advanced degree preferred.
• 7+ years of pharmaceutical, biotech, CRO, or related clinical research experience.
• Strong experience in vendor oversight, outsourcing, site contracts, investigator payments, or related operational functions required.
• Experience working cross-functionally with AP, Procurement, Finance, and Legal required.
• Experience working in SAP/4 Hanna preferred.
• Experience establishing KPIs and oversight models preferred.
• Oncology, cell therapy, or early-phase clinical operations experience preferred.
• Ability to travel as necessary (up to 10%).
• Effective oral, written, and interpersonal communication skills.
• Strong process management, organizational, and problem-solving skills.
• Ability to identify operational risk and drive practical mitigation strategies.
• Strong project management skills and the ability to manage multiple priorities.
• Computer literacy required (MS Word, MS Excel, MS PowerPoint, MS Project).
• Working knowledge of GCP, FDA, and ICH Guidelines.

#Li-JR1

#Li-Hybrid

Legend Biotech is seeking a Manufacturing Engineer, Technical Support as part of the Technical Operations team based in Raritan, NJ.

Role Overview

The Manufacturing Engineer, Tech Support will be part of the Technical Support team and be responsible to support the development and routine operation of a new CAR-T manufacturing process. They will be a subject matter expert for the manufacturing process and equipment primarily responsible for providing front line support to address and resolve manufacturing issues.

Key Responsibilities

• Partner closely with Quality, Compliance, and technical experts to drive accelerated, robust, and consistent resolution and escalation of process issues as applicable while ensuring batch quality and adherence to procedures and instructions.
• Support compliant manufacturing investigations and CAPAs, as subject matter experts.
• Review batch records updates to ensure alignment with the manufacturing process.
• Be a point of contact with equipment suppliers for timely and continuous support.
• Support the monitoring of the manufacturing process and process execution to identify and support opportunities for improvement and waste reduction.
• Represent the technical support team when interfacing with other departments.
• Perform regular manufacturing operations to collect process health data for the identification of process improvement and waste reduction opportunities.
• Job duties performed routinely require exposure to and handling of biological materials and hazardous chemicals.
• Distance visual acuity of at least 20/40 (Snellen) in both eyes without corrective lenses or visual acuity corrected to 20/40 (Snellen) or better with corrective lenses.
• Color Perception both eyes 5 slides out of 8.
• Will be able to make most troubleshooting suggestions, and will work with partners in operations in quality to reach final decisions. For troubleshooting that leads to high process impact, an associate engineer will escalate to our senior team members. Manufacturing engineers will act independently as subject matter experts, especially when working with the Legend investigations team. Manufacturing engineers will independently make procedural updates and perform continuous improvement work.

Requirements

• A minimum of a Bachelor’s degree in engineering or related field or equivalent experience required. Advanced degree preferred.
• 3-5 years of operations experience within a cGMP environment in the biotech/biopharma industry and Cell/Gene Therapy cGMP manufacturing experience preferred.
• Fundamental proficiency with the Microsoft office suite.
• Familiarity with Power Apps, Power BI, and Tableau preferred.

#Li-RN1

#Li-Onsite

Legend Biotech is seeking an Operations Supervisor as part of the Technical Operations team based in Raritan, NJ.

Role Overview

The CAR-T Operations Supervisor is an exempt level position working within Technical Operations team, responsible for directing the daily production of a personalized cell therapy to support both clinical and commercial requirements in a sterile cGMP environment. Job duties will be performed within a team-based environment, on an assigned production shift schedule.

Shift Options Available:

• Wed–Sat, 2nd Shift

Key Responsibilities

• Lead and supervise multiple units within the CAR-T process operations (i.e. component preparation manufacturing, MFG support operations, Mock cell, and CAR-T process) according to standard operating procedures and batch records and ensure safe and compliant manufacturing operations according to cGMP requirements.
• Lead the daily start of shift operations meetings, the daily wrap up production meetings and assign individuals their daily production task to execute and ensure compliance and successful completion of work-related tasks.
• Work closely with operations personnel on the production floor to provide guidance and perform production tasks as needed to help the team, in a manner consistent with safety policies, quality systems, and cGMP requirements.
• Support manufacturing investigations, create/revise operational procedures, including manufacturing work instructions, master batch records, forms, and support and manage change controls.
• Work closely with Operations Manager to help oversee the development of production personnel, provide input on personnel performance.
• Build strong partnerships with Manufacturing, Engineering, and Quality to ensure seamless execution of daily production tasks and work as part of a cross-functional team to address production issues as the first point of contact for operators on the production floor.
• Support the development of manufacturing processes, participate in various department projects, and will work with others to drive continuous improvements and efficiencies within cell therapy Technical Operations.
• Job duties performed routinely require exposure to and handling of biological materials and hazardous chemicals.
• Distance visual acuity of at least 20/40 (Snellen) in both eyes without corrective lenses or visual acuity corrected to 20/40 (Snellen) or better with corrective lenses.
• Color Perception both eyes 5 slides out of 8. 

Requirements

• Bachelor’s degree in Science, Engineering or related field or equivalent experience required.
• A minimum of 6 years of operations experience within a cGMP environment in the biotech/biopharma industry. Prior experience in manufacturing, quality, or engineering is required.
• Excellent communication and organizational behaviors skills are required.
• Proficiency with Microsoft Office tools (Word, Excel, PowerPoint, and Outlook) is required.
• Availability to work in a day shift (1st or 2nd shift) is required.
• Knowledge of cGMP regulations and FDA guidance related to manufacturing of cell-based products, and cleanroom behaviors.
• Must exhibit strong Leadership skills and ability to effectively communicate and influence Operations associate and convey information to Management.
• Ability to work independently and successfully, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively.
• Must be able to manage shifting priorities to meet critical deadlines in a fast paced and dynamic, growing environment, while providing clear direction to team members.
• Strong analytical, problem solving and critical thinking skills and the ability to lead as a change agent to promote flexibility, creativity, and accountability.
• An ability to build strong partnerships and effectively integrate with external collaborators to drive projects/programs forward in a matrixed environment.
• Clear and succinct verbal and written communication skills with an attention to detail and the ability to follow procedures.
• Experience with Operational Excellence and/or Lean Manufacturing is an asset.
• Ability to accommodate shift work including evenings and weekends as required by the process.
• Ability to accommodate unplanned overtime on little to no prior notice.
• Sufficient vision and hearing capability to work in job environment with physical dexterity sufficient to use computers and document production records
• A working leader who can participate in production runs in critical situations when needed.
• Ability to lift a minimum of 25 lbs. and stand for a long period of time. 

#Li-RN1

#Li-Onsite

Legend Biotech is seeking a Principal Scientist, Clinical Biomarker, Immunology, Immuno-Oncology, & Hematology (Contractor) as part of the Research & Development team based in Somerset, NJ.

Role Overview

We are seeking a highly motivated and innovative Principal Scientist to join our immunology and immuno-oncology (IO) clinical biomarker projects, with a dedicated focus on hematological malignancies. In this role, you will drive the clinical translational understanding of novel therapy in hematology. You will serve as the biology lead on cross-functional project teams, drive MOA of novel cell therapy and clinical biomarker strategy.

Contract Duration: 12 months

Key Responsibilities

• Scientific Leadership: Design, execute, and analysis results from clinical studies to investigate the mechanisms of action for novel IO targets in hematological indications (e.g., AML, DLBCL, Multiple Myeloma).
• Translational Strategy: Bridge discovery and clinical development by utilizing primary human samples and clinical datasets to validate targets and understand the immune microenvironment in hematology.
• Understanding MOA: Oversee the generation and interpretation of high-dimensional molecular and cellular data. Leverage advanced single-cell technologies (e.g., scRNA-seq) to deeply profile immune cell compartments, particularly T-cell states and exhaustion markers, to inform patient stratification and biomarker hypotheses.
• Cross-Functional Collaboration: Partner closely with other functional teams for better understanding of MOA and fundamental immunology

Requirements

• Ph.D. in Immunology, Immuno-Oncology, Cellular Biology, or a closely related discipline, can initiate and lead data driven MOA studies. Experience with cell therapy a plus but not required.
• A minimum of 5-8+ years of post-doctoral and/or industry experience in biotech or pharma, with a proven track record of advancing IO programs. Deep understanding of immunology, particularly T cell biology highly desirable.
• Deep biological understanding of hematological malignancies and the unique tumor immune microenvironment of the blood and bone marrow.
• Experience working with multiple dimensional data, extract biological insights from data highly desirable.
• Exceptional written and verbal communication skills, with the ability to distill complex data into clear, actionable strategic decisions.

#Li-JR1

#Li-Contract

Legend Biotech is seeking candidates for Legend's Finance Management Leadership Development Program as part of the Finance team based in Somerset, NJ.

Role Overview

The Early Career Leadership Program at Legend Biotech is a strategic, enterprise-focused development experience designed to accelerate the growth of high-potential professionals early in their careers. Rooted in our commitment to cultivating enterprise-minded, value-driven leaders, this program provides structured rotational exposure, executive mentorship, and real-time business impact across scientific, operational, and corporate functions.

Join us in redefining what’s possible and build a career where your growth and patient impact go hand in hand. 

Key Responsibilities

• The Finance Management Hi-Po Leadership Development Program is a 2-3-year enterprise leadership accelerator designed for high-potential MBA graduates ready to influence financial strategy in a fast-growing, innovation-driven biotech organization. Through 3-4 strategic rotations (8-12 months each) which may include Finance & Accounting, Procurement, Corporate Finance, and Internal Audit, you will gain deep technical expertise and broad enterprise perspective.
• This structured program integrates high-impact business experiences, executive mentorship, and a Leadership Development Series focused on developing leaders at every level, from leading self and others to influencing senior stakeholders. and driving enterprise-wide business outcomes.
• At Legend Biotech, we believe our people are our greatest asset. This program reflects our unwavering commitment to professional development, career mobility, and long-term leadership growth; empowering early-career talent to take on meaningful challenges, expand their impact, and shape the future of our organization.

Requirements

• Recent MBA graduate (Class of 2023–2026), with concentration in Finance, Accounting, or related field preferred.
• 2-3 years of professional experience demonstrated progressive responsibility and analytical rigor.
• Strong financial modeling, problem-solving, and communication skills.
• Demonstrated leadership potential and aspiration to grow into Director-level and broader enterprise finance leadership roles.
• Demonstrated skills in developing and implementing enterprise technology automation, visualization and analytics solutions to improve productivity and performance. 

#Li-

#Li-

Legend Biotech is seeking participants for Legend's Commercial Management Leadership Development Program as part of the Commercial team based in Somerset, NJ.

Role Overview

The Early Career Leadership Program at Legend Biotech is a strategic, enterprise-focused development experience designed to accelerate the growth of high-potential professionals early in their careers. Rooted in our commitment to cultivating enterprise-minded, value-driven leaders, this program provides structured rotational exposure, executive mentorship, and real-time business impact across scientific, operational, and corporate functions.

Join us in redefining what’s possible and build a career where your growth and patient impact go hand in hand.

Key Responsibilities

• The Commercial Management Hi-Po Leadership Development Program at Legend Biotech is a 2–3-year enterprise leadership accelerator designed for high-potential MBA graduates who aspire to shape the future of biotech commercialization. This program develops leaders capable of translating scientific innovation into meaningful patient access and market impact.
• Participants will complete three strategic rotations (8–12 months each) that may include Marketing, Market Access & Branding, Commercial Operations, Sales, and Business Insights & Analytics. Rotations are designed to provide both broad commercial exposure and the opportunity to pursue areas aligned with individual interests and development goals. Participants will develop the strategic, analytical, and leadership capabilities needed to influence commercial strategy and drive business growth
• This structured program integrates high-impact business experiences, executive mentorship, and a Leadership Development Series focused on developing leaders at every level — from leading self and others to influencing senior stakeholders and driving enterprise-wide business outcomes.
• At Legend Biotech, we believe our people are our greatest asset. This program reflects our unwavering commitment to professional development, career mobility, and long-term leadership growth; empowering early-career talent to take on meaningful challenges, expand their impact, and shape the future of our organization.

Requirements

• Recent MBA graduate (Class of 2023–2026)
• 3-5 years of professional experience demonstrating analytical and leadership capability.
• Background in life sciences, healthcare, marketing, sales, business analytics, or management consulting preferred.
• Strong analytical, communication, and strategic problem-solving skills.
• Demonstrated leadership potential and aspiration to grow into future commercial and enterprise leadership roles.

#Li-CC1

#Li-Hybrid

Legend Biotech is seeking a HR Management, Leadership Development Program as part of the Human Resources team based in Somerset, NJ.

Role Overview

The Early Career Leadership Program at Legend Biotech is a strategic, enterprise-focused development experience designed to accelerate the growth of high-potential professionals early in their careers. Rooted in our commitment to cultivating enterprise-minded, value-driven leaders, this program provides structured rotational exposure, executive mentorship, and real-time business impact across scientific, operational, and corporate functions.

Key Responsibilities

• As an HR Management participant within this program, you will build the strategic, operational, and leadership capabilities required to drive talent outcomes in a fast-growing, mission-driven biotech organization. The experience is intentionally designed to strengthen succession readiness for critical leadership roles while equipping you with the cross-functional perspective and business acumen needed to lead at scale.
• At Legend Biotech, we believe our people are our greatest asset. This program reflects our unwavering commitment to professional development, career mobility, and long-term leadership growth; empowering early-career talent to take on meaningful challenges, expand their impact, and shape the future of our organization.
• Complete 3-4 cross-functional rotations over a 3-year structured leadership program (8-12 months per rotation) across Talent Acquisition, HR Operations, HR Business Partnering, Total Rewards, and/or Learning & Organizational Development.
• Lead and support high-impact HR initiatives aligned to talent strategy, organizational design and workforce planning.
• Partner with senior leaders to solve complex organizational challenges and drive scalable HR solutions aligned to enterprise growth.
• Participate in a Leadership Development Series focused on strategic thinking, executive presence, and enterprise leadership readiness.
• Deliver measurable business impact and progressively increase scope, influence and accountability across rotations.

Requirements

• Recent MBA or MA graduate (Class of 2023-2026) in Human Resources or related field.
• 2–3 years of professional experience (HR or related business experience preferred).
• Preferred experience in a Life Sciences organization or related business.
• Demonstrated leadership potential, strong analytical and communication skills, and a desire to grow into future leadership roles.

#Li-CC1

#Li-Hybrid

Legend Biotech is seeking a Chief Scientific Officer as part of the Research & Development team based in Somerset, NJ.

Role Overview

Legend Biotech is recruiting a visionary scientist, an accomplished drug hunter and a skilled organization/business leader as Chief Scientific Officer (CSO). The CSO will lead and oversee the global Research strategy and operations and is responsible for driving the scientific vision and overseeing research activities. The CSO is expected to deliver highly innovative and industrial-leading technology platforms and transformative therapies from initial concept to Development Candidate. Reporting to President of Research and Development, the CSO will be responsible for integrating all global technological innovation and drug discovery strategies and operations to bring cutting-edge therapies to patients.

Key responsibilities include developing and implementing the company’s scientific strategy, managing the Research budget, mentoring scientific staff, and collaborating with stakeholders to bring innovative products and solutions to the market. The CSO will also play a critical role in evaluating new technologies, partnerships, and investment opportunities.

This role requires a deep understanding of scientific principles, strong leadership skills, and the ability to translate complex research into actionable business strategies. As the CSO, you will work closely with executive leadership, product development teams, and external partners to drive innovation and maintain our position at the forefront of cell therapy. You will be expected to stay abreast of emerging trends and technologies, foster a culture of impactful innovation and scientific excellence, and ensure compliance with regulatory standards.

The ideal candidate should have a strong background in scientific research, preferably with a Ph.D. in a relevant field, and a proven track record of leading successful Research programs and delivering multiple compounds into clinic development. You should be skilled at managing global multidisciplinary teams and representing the company in scientific and regulatory forums.
This is a high-impact role that offers the opportunity to shape the future of our organization through scientific leadership and innovation. If you are an innovative scientist and an accomplished drug hunter and are passionate about science with the strategic vision to lead cutting-edge research, we encourage you to apply.

Key Responsibilities

• Develop disease centric global research strategy and deliver a robust, diversified and risk-balanced pipeline of therapeutics.
• Develop and implement global technology and drug discovery plans that align with the company’s business objectives, advancing the company’s pipeline of cell therapies from technology innovation to Development Candidates.
• Oversee global research programs through key milestones, including technological platform innovation and drug discovery, while efficiently managing resources to meet timelines.
• Manage global research budget and ensure resource allocation aligned with strategic priority and efficient return of investment.
• Drive the identification and evaluation of new technologies, research opportunities, partnerships, collaborations and licensing opportunities via BD to expand the company’s pipeline and market position.
• Attract, retain, and develop top talent within the global research organization, fostering a culture of innovation, collaboration, and scientific excellence.
• Serve as a key member of the executive leadership team, contributing to overall corporate strategy and decision-making.
• Stay abreast of industry trends, regulatory changes, and scientific advancements, ensuring compliance and maintaining the company’s leadership position in cell therapy development.

Requirements

• PhD or equivalent advanced degree in a relevant scientific field (e.g., immunology, oncology, molecular biology).
• Minimum of 15 years of experience in Research leadership roles within the biopharma and biotech industry, with a strong focus on cell therapy or immunotherapy.
• World-class scientific accomplishments demonstrated by a strong record of cutting-edge research publications and patents.
• Proven track record of successfully advancing multiple therapies from research through early clinical development.
• Extensive experience managing large, global, cross-functional teams and growing top talents.
• Deep understanding of the global development and regulatory landscape for cell and gene therapies.
• Strategic thinker with strong business acumen and the ability to align Research activities with overall company goals.
• Exceptional leadership and team-building skills, with a demonstrated ability to inspire and lead high-performing teams.
• Excellent communication, collaboration and interpersonal skills, with the ability to influence and engage a wide range of stakeholders.
• Strong analytic and problem-solving skills, with the ability to navigate complex challenges and drive decision-making in a fast-paced environment.

#Li-AS1

#Li-Hybrid

Legend Biotech is seeking a HR Policy & Risk Manager (Contractor) as part of the Human Resources team based in Somerset, NJ.

Role Overview 

The HR Policy & Risk Manager plays a critical role in ensuring that HR operations and programs align with internal controls, external regulation and company risk management strategies. The role functions across multiple workstreams focused on risk identification, control implementation, policy compliance and internal auditing. This is a second line of defense role, providing oversight of HR risks, compliance and governance in alignment with broader enterprise risk management

Key Responsibilities

• Oversee the implementation and monitoring of controls across HR policies and processes, ensuring ownership by functional leads.
• Conduct quarterly control assessments and support function leads in evaluating control effectiveness.
• Lead or support internal HR audits, both scheduled and ad hoc, documenting findings and driving remediation actions.
• Monitor and assess HR risks using data-driven metrics (e.g., attrition, time-to-fill), investigate root causes and support resolution efforts
• Partner with reporting team to track HR risk indicators and ensure timely mitigation of emerging issues.
• Maintain oversight of employee investigations conducted to ensure objectivity and compliance monitoring.
• Monitor data privacy-related activities to ensure alignment with legal and regulatory standards
• Develop, maintain, and govern HR policies and procedures in accordance with internal standards and regulatory expectations.
• Own SOX-related HR controls, ensuring documentation, testing and remediation are completed accurately and on time.
• Contribute to company-wide compliance and risk management by representing HR-related risks.
• Prepare risk reports and audit summaries for HR leadership, internal audit and as needed.
• Serve as a central point of contact for HR risk, audit, and policy-related inquiries across the organization.
• Decides when to escalate HR risks, compliance issues, and investigation outcomes to leadership.
• Determines control priorities and remediation actions based on risk assessments and audit findings
• Evaluates and approves updates to HR policies, procedures, and SOX controls to meet regulatory and business needs.
• Identifies data trends and root causes to inform risk mitigation strategies.

Requirements

Education

• Bachelor’s degree in Human Resources, Business Administration, Risk Management, Compliance or a related field required.
• Master’s degree in HR, Business, Law, or a related discipline a plus.
• Relevant certifications preferred (e.g., PHR/SPHR, SHRM-CP/SCP, Certified Compliance & Ethics Professional – CCEP).

Experience

• Minimum of 5 years of experience in HR, compliance, internal audit, risk management or a similar function.
• Experience in a fast-paced professional environment and working with cross-functional teams.
• Strong understanding of risk management principles and compliance frameworks.
• Familiarity with HR systems, data privacy laws (e.g., GDPR, CCPA), and internal audit practices.
• Strong analytical skills to interpret HR metrics and identify trends or red flags.
• Excellent communication and stakeholder management, especially when partnering with HR, Legal, Audit, and Risk functions.
• High attention to detail, integrity, and ability to maintain confidentiality.
• Critical thinking and problem-solving mindset with a proactive approach to compliance.

IT Skills 

• Advanced Excel skills for data analysis and risk reporting (pivot tables, lookups, dashboards). 
• Proficiency with HRIS (Workday) and audit/compliance tools.
• Familiarity with data visualization or reporting tools (e.g., Power BI). 
• Experience with document management and workflow tools (e.g., SharePoint, SmartSheet).

#Li-FB1

#Li-Hybrid

Legend Biotech is seeking a Continuous Improvement Facilitator as part of the Technical Operations team based in Raritan, NJ.

Role Overview

This position provides operational excellence support to the cGMP Clinical and Commercial Cell Therapy Manufacturing plant.

The Continuous Improvement Facilitator will lead and support a broad range of continuous improvement initiatives for CAR-T Manufacturing, ensuring alignment with site objectives and operational priorities. This role focuses on identifying improvement opportunities, implementing structured problem-solving methodologies, and driving sustainable operational improvements.

The role will require strong facilitation and communication skills to support the deployment of continuous improvement programs. The facilitator will collaborate across cross-functional teams to strengthen a problem-solving culture which supports the timely production, testing, and release of life-saving therapies to patients.

Key Responsibilities

• Support the planning, development, and execution of a continuous improvement initiatives using Lean and Six Sigma manufacturing methodologies, such as standardized work, PDCA, metrics, visual tools, 5S/6S, FMEA, Pareto analysis, and others to improve safety, compliance, cost, process stability, and efficiency.
• Design and implement data collection systems to support operational performance monitoring and continuous improvement initiatives, leveraging tools such as Power BI and Power Automate to automate workflows, visualize key metrics, and enhance data-driven decision-making.
• Facilitate and lead Kaizen events and improvement workshops aimed at improving process performance, reducing waste, driving right-first-time execution, and increasing operational productivity.
• Lead and support value stream mapping exercises, identify bottlenecks and inefficiencies, and collaborate with teams to develop improvement plans to streamline operations.
• Deliver training to team members across different functions in Lean tools, techniques, and methodologies, fostering a culture of problem-solving and continuous improvement at all levels of the organization.
• Support the implementation of key CI projects, assisting with tracking progress, managing resources, and reporting on the outcomes.
• Track and measure the impact of CI initiatives through relevant metrics and KPIs, providing regular updates to leadership on progress and areas of focus for continued improvement.
• Apply and coach change management principles within Operations to support the successful adoption and sustainment of improvements.
• Partner with Operational Excellence and Project Management Office to implement improvements across the organization.

Requirements

• BS/BA required in technical discipline: Engineering, science or similar field
• Lean Six Sigma Green preferred.
• GMP Manufacturing, Quality, Supply Chain experience in the biotech/biopharma industry. Cell/Gene Therapy cGMP manufacturing experience preferred.
• Minimum of 2 years of experience leading and/or supporting continuous improvement, operational excellence, or process improvement within a manufacturing or regulated environment (e.g., cGMP)
• Knowledge of Lean and/or Six Sigma methodologies and their practical application to improve processes in operational environments such as Manufacturing, Quality, or Supply Chain.
• Experience facilitating Kaizen events and value stream mapping exercises.
• Strong understanding and proven application of problem-solving tools and techniques.
• Ability to engage all levels of the organization, from site leadership to the shop floor.
• Proven experience working and leading in a matrix environment.
• Excellent communication, interpersonal, and team-building skills, with the ability to influence and engage individuals at all levels of the organization.
• Able to manage shifting priorities to meet critical deadlines in a fast paced and dynamic, growing environment.
• Strong ownership skills and ability to work independently.
• Strong analytical, problem solving and critical thinking skills.
• Proficiency in Microsoft Office Suite (Excel, PowerPoint, Word).
• Proficiency in MS Teams, PowerBI, PowerAutomate preferred.
• An ability to build strong partnerships and effectively integrate with external collaborators to drive projects/programs forward in a matrixed environment.
• Ability to work independently and successfully, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively.
• Clear and succinct verbal and written communication skills with an attention to detail and the ability to follow procedures.
• Knowledge of cGMP regulations and FDA guidance related to manufacturing of cell based products.
• Solution-oriented mentality, capable of developing new procedures and alternate paths to overcome identified opportunities for improvement.

#Li-RN1

#Li-Onsite

Legend Biotech is seeking a Legal Operations Manager, Contracts & Privacy as part of the Legal team based in Bridgewater, NJ.

Role Overview

The Legal Operations Manager, Contracts & Privacy supports the Legal Department by managing day-to-day contract lifecycle administration, coordinating operational aspects of the company’s Global Privacy program and assisting with legal operations processes and tools. This role is highly execution-oriented and works closely with attorneys and cross-functional partners to ensure efficient, compliant, and well-organized legal workflows in a fast-paced biotech environment. The position will coordinate closely with Legend Biotech’s Chief Privacy Officer and reports to Legend Biotech’s Deputy General Counsel.

Key Responsibilities

Contract Lifecycle Administration

• Coordinate the end-to-end contract process, including intake, routing, approvals, execution, and filing
• Maintain and update contract records in the company’s CLM system, ensuring accuracy and completeness of data
• Ensure contracts comply with company standards, regulatory requirements, and approval processes
• Populate basic contract template agreements (e.g. NDAs, consulting agreements, etc.)
• Track contract status, key dates (e.g., expirations, renewals), and obligations
• Assist in maintaining contract templates, standard forms and clause libraries
• Respond to internal inquiries regarding contract status and process
• Perform other contracts-related activities and tasks as assigned

Privacy Program Support

• Support day-to-day operations of the company’s Global Privacy program
• Assist with privacy impact assessments, security risk assessments and other privacy reviews and documentation
• Maintain records related to data processing activities and ensure compliance with data subject right requests
• Help coordinate privacy training, awareness initiatives and policy updates
• Track and escalate privacy-related issues and requests to appropriate stakeholders
• Organize and coordinate privacy champions meetings to ensure privacy requirements are understood and implemented
• Coordinate implementation of data mapping plan to maintain up to data inventory, liaising with system/business owners, and assist with other EU GDPR operational matters
• Track key privacy metrics (e.g., breaches report, PIAs conducted, DSARs received)
• Assist with clinical trial privacy matters, including informed consent (ICF) updates, investigator/HCP notice, and related matters

Legal Operations Support

• Maintain organized legal files, databases, and corporate records
• Support subsidiary management across US & EU jurisdictions
• Support reporting efforts by compiling basic KPIs, metrics and data for the Legal Team
• Assist with invoice processing and vendor onboarding as needed
• Support implementation and ongoing management of legal systems and tools

Requirements

• Bachelor’s degree or equivalent experience required
• 4+ years of experience in legal coordination, contract administration, paralegal support or legal operations
• Experience with contract management systems or similar tools strongly preferred
• Basic familiarity with data privacy concepts and regulations (e.g., GDPR, CCPA, HIPAA) is a plus
• Strong organizational and administrative skills with high attention to detail and accuracy
• Ability to manage multiple tasks and deadlines effectively
• Effective communication and responsiveness
• Ability to follow established processes and identify opportunities for improvement
• Comfort working with systems, data and cross-functional teams

#Li-FB1

#Li-Hybrid

Legend Biotech is seeking a Commercial Marketing Coordinator (Contractor) as part of the Commercial team based in Bridgewater, NJ.

Role Overview

The Commercial Marketing Coordinator position involves engaging with a multitude of internal and external stakeholders, at varying levels across organizations, and requires exceptional interpersonal, communication, and project management skills, along with a solution-oriented mindset. The position requires high-level execution of tasks while maintaining a positive and professional approach. Key responsibilities include calendar management, overseeing of internal review processes, managing external vendor onboarding, and supporting various commercial workflows. The ideal candidate will demonstrate accuracy, efficiency, and adaptability, with proficiency in IT tools and a willingness to learn financial, strategic, and operational systems.

Contract Duration: 12 months

Key Responsibilities

• Proactively manage calendars with clear communication, timely follow-through, and real-time scheduling adjustments.
• Support U.S. Commercial Organization activities, ensuring alignment with departmental priorities.
• Co-develop and implement processes that drive departmental and cross-functional goals and pull-through.
• Serve as an in-house expert for department projects, including prioritization, ownership of special initiatives, and oversight of internal review processes.
• Collaborate with Commercial Leadership Team and internal partners to ensure timely progression of reviews.
• Assist in preparing materials and presentations for internal and external meetings.
• Draft and manage business correspondence with accuracy and professionalism.
• Maintain efficient information flow across all levels and between internal and external stakeholders.
• Support contract and purchase order requests, and ensure accurate, timely processing of invoices and expenses.

Requirements

• Bachelor's Degree preferred.
• 5+ years of direct experience supporting departments with both in-house and/or field employees.
• Experience supporting Commercial teams within the biopharmaceutical industry preferred.
• Experience managing multiple calendars with competing priorities and composing business correspondence.
• Experience supporting multiple Executives and Directors in a fast-paced environment, as part of an administrative support team.
• Proven ability to handle confidential information with complete discretion and maturity, and the ability to deal with ambiguity by using good judgment.
• Strong organizational skills that reflect the ability to perform and prioritize competing tasks.
• Flexibility to work across different time zones.
• Strong decision-making, problem-solving, time management, and organizational skills.
• Great interpersonal skills, with the ability to work with a wide variety of internal customers and external business contacts.
• Excellent attention to detail.
• Excellent written and verbal communication skills.
• Excellent computer skills including a high proficiency with MS Office.
• Willingness to go above and beyond to get things done.
• Ability to multitask efficiently, excelling at synthesizing and coordinating multiple communications, activities, and competing tasks in a fast-paced and dynamic environment.
• Enjoys working cross-functionally in partnership with teams.
• Impeccable communication skills with a skill for establishing strong relationships.
• Takes initiative by anticipating, addressing, and resolving potential needs, conflicts, or challenges.

#Li-JK1

#Li-Hybrid

#Li-Contract

Legend Biotech is seeking a Junior Associate Facility Engineer as part of the Facilities & Engineering team based in Raritan, NJ.

Role Overview

The Associate Facility Engineer will support the operation, maintenance, and qualification of equipment and systems that enable a Cell Therapy manufacturing facility. This person will assist in equipment monitoring, documentation, and troubleshooting activities under the guidance of more senior engineers. The role requires technical curiosity, attention to detail, and the ability to work in a collaborative team environment. This individual will be part of the CAR-T Equipment team in support of clinical and commercial manufacturing as well as facility improvement initiatives.

Key Responsibilities

• Provide day-to-day technical support for equipment and process support installations. 
• Assist in maintaining reliability and compliance through preventive maintenance programs and equipment monitoring.
• Learn to recognize performance trends, document observations, and propose basic improvements that enhance reliability, safety, and quality.
• Support the development of maintenance and calibration records, work instructions, and SOPs within the Quality Management System.
• Participate in root cause investigations, CAPAs, and change controls by gathering data, preparing documentation, and collaborating with cross-functional teams including QA, Operations, and Validation.
• Work with technical equipment data and documentation to support analyses of the maintenance process and provide input to the Maintenance Manager.
• Help ensure that preventive maintenance and calibration activities are completed and recorded on time.
• Assist with equipment tracking, asset management system updates, and vendor communication under supervision.
• Contribute to improvement projects or new equipment introductions by supporting data collection, documentation, and basic technical evaluations.
• Interact with external service providers and support internal teams to ensure timely execution of service activities.
• Have the authority to make decisions related to technical direction, methodologies, approaches and product development processes. You can also make decisions related to project execution, including timelines, milestones and resource allocation approved by the engineering manager. Higher-level approvals are required for those related to significant batch impact, or elevated resource allocation as directed by engineering manager.

Requirements

• Bachelor’s Degree – Preferably in Engineering or Life Sciences.
• 0–2 years of experience in Facility, Engineering, or Operations (internship or co-op experience in a GMP setting preferred).
• Proficiency of Microsoft office.
• Experience with quality management systems.
• Maximo or SAP.

#Li-RN1

#Li-Onsite

Legend Biotech is seeking a Leadership Excellence & Acceleration Pathway Associate as part of the Commercial team based in Bridgewater, NJ.

Role Overview

The Leadership Excellence & Acceleration Pathway (LEAP) Associate is a selective, high-impact role designed to accelerate the development of the next generation of commercial leaders at Legend Biotech.

LEAP Associates participate in a structured, end-to-end commercial development experience spanning key commercial functions, paired with real accountability, senior leader exposure, and hands-on ownership of meaningful business work. The program is intentionally designed for high-potential professionals who have demonstrated strong execution, leadership maturity, and a desire to grow into broader commercial leadership roles within biotech.

Unlike traditional entry-level or functional roles, LEAP Associates are positioned as enterprise-minded contributors, expected to think strategically, execute rigorously, operate across functions, and continuously elevate how work gets done, including through modern, AI-enabled ways of working.

Upon successful completion, participants are expected to be ready for expanded-scope commercial roles within the organization.

Program Overview

• 18-24 month structured rotational development program.
• Exposure across core commercial functions such as: Field Sales, Marketing, Market Access.
• Embedded learning curriculum focused on:
  • End-to-end commercial strategy and execution.
  • Cross-functional leadership and influence.
  • Decision-making in complex, data-rich environments.
  • Responsible and practical application of AI in commercial work.
  • Ongoing mentorship, performance feedback, and senior leader engagement.

(Specific rotation assignments and sequencing will be determined based on business priorities and developmental needs.)

Key Responsibilities

• Across the program, LEAP Associates will be expected to:
• Drive execution by contributing to priority commercial initiatives and business-critical projects across functions.
• Translate strategy into action, supporting planning, analysis, and execution efforts that directly impact commercial performance.
• Operate cross-functionally, effectively partnering with Sales, Marketing, Market Access, Commercial Operations, and other stakeholders.
• Bring structure and insight to ambiguity, using data, judgment, and stakeholder input to support sound decision-making.
• Demonstrate ownership and accountability for outcomes—not just deliverables.
• Build influence without authority, navigating complex stakeholder environments with professionalism and credibility.
• Continuously elevate ways of working, including identifying opportunities to improve efficiency, rigor, and scalability.

AI-Enabled Ways of Working

A core expectation of the LEAP program is the development of applied AI fluency. LEAP Associates will:

• Leverage approved AI tools to support:
  • Commercial analysis and insight generation.
  • Planning and scenario evaluation.
  • Content development and communication.
  • Workflow efficiency and execution effectiveness.
• Apply AI responsibly and in alignment with company governance and standards.
• Identify and share best practices for integrating AI into everyday commercial work.
• Help translate AI-enabled capabilities to teams and stakeholders, supporting broader adoption and impact.

AI is treated as a practical leadership capability, not a theoretical skillset.

Requirements

Required:

• Bachelor’s degree.
• 5–7 years of professional experience.
• Demonstrated track record of execution, ownership, and results delivery.
• Strong analytical, communication, and problem-solving skills.
• Interest in biotech/pharma and commercial leadership pathways.

Preferred:

• Experience in disciplined, performance-driven environments (e.g., military service or similarly structured settings).
• Exposure to commercial, operational, analytical, or customer-facing roles.
• Experience using data, analytics, digital tools, or AI-enabled solutions to support decision-making.
• Comfort working in complex, matrixed organizations.

Developmental Opportunities:

• Exposure to senior leadership.
• Cross-functional rotations.
• Mentorship and coaching.
• Potential placement into full-time commercial roles upon program completion.

#Li-SD1

#Li-Hybrid

Legend Biotech is seeking a Manager of Internal Audit as part of the Internal Audit team based in Bridgewater, NJ. 

Role Overview

Legend Biotech (the Company) seeks a high performing manager to join the Internal Audit (IA) department. This individual will be responsible for leading a broad range of Sarbanes-Oxley Act (SOX) control testing and internal audits including, but not limit to, Financial, Operational, Compliance, Technology audits and special projects independently and proficiently, following the COSO Framework and Institute of Internal Auditor (IIA) Standards.

The key objective of this role is to provide an independent and objective assessment of, as well as add value to improve the Company's control and operation environment to ensure compliance, effectiveness and efficiency. The Manager of Internal Audit will apply IA’s Policy and Procedure to skillfully manage audit lifecycle from planning, to scoping, fieldwork, reporting and following through audit remediations. This role will report to the Global Head of Internal Audit and collaborate with other IA team members, business process owners, key stakeholders, and external auditors.

The key characters expected to the Internal Audit Manager include being risk conscious, control driven, critical thinking, proactive, relationship building, strong written and verbal communication skills, multi-tasking, time management, team player, and act with sense of urgency and ownership.

Key Responsibilities  

• Manage internal audit risk assessment, develop audit universe, identify auditable projects, and conduct risk-based audit project planning and scoping.
• Follow Internal Audit Methodology and Procedure to manage audit lifecycle from audit planning to audit reporting to meet audit objectives and to ensure compliant, effective and efficient processes and controls are in place:
  • Gather critical audit related information via asking probing questions in interviews with key process owners, to assess business processes and the maturity of their control environments.
  • Conduct data analysis in risk assessment and execution of audits.
  • Be able to independently develop and clearly articulate a risk-based audit program to clearly include risks, objective, control, and test steps.
  • Hands on manage testing process that address high risk areas in scope in accordance with Legend Internal Audit and IIA Standards.
  • Identify control gaps, improvement opportunities, and value-added recommendations to strengthen and improve the control environment.
  • Review project team member’s workpaper for completeness, accuracy, adequacy and compliance.
  • Evaluate the risk and potential business impact of identified deficiencies.
  • Document audit workpapers with reperformance standards to include test attributes, associated risks, test conclusions, and opportunities for process improvement.
• Independently conduct and document the walkthroughs and tests of controls, to evaluate the effectiveness of the Company’s SOX 404 program.
• Track identified audit deficiencies/observations and ensure the completion of audit remediations.
• Collaborate with and educate process owners on the importance of maintaining strong controls.
• Build strong relationship with business functions and act as a trusted business partner to provide expert insights in the areas of operational audits and SOX audits where the incumbent will review, evaluate and recommend actions to improve control and risk management.
• Proactively engage in various departmental activities to help build Internal Audit brand name, promote integrity-culture within company, and develop junior staff through positive and energetic mindset.
• Act with sense of urgency and strong accountability to work in a fact growing company; being a role model to demonstrate professional due care; being sensitive to various operational risks and strong sense of control; being able to articulate thought process and communicate concisely verbally and in written (email, workpaper, audit report); being able to hands on and work with junior staff to help them grow professionally; being able to keep Audit Leader closely updated on different risks, project status, challenges, and/or new ideas etc.
• Passionate about Internal Audit profession, and be able to actively participate all kinds of internal audit training program to advocate internal audit mission statement and value proposition, and goal of partnering with business stakeholders in building a more effective process and culture of integrity together.

Requirements

• Bachelor’s degree from an accredited college / university required
• Masters, MBA, or CPA, CIA, CISA, CISM strongly preferred, especially CFE
• Minimum 6 years of experience in auditing (combination of internal and/or external).
• Experience with Sarbanes-Oxley (SOX) is required.
• Experience with operational audits is required.
• Fraud examination experience is strongly preferred.
• Experience in Public Accounting is preferred.
• Critical thinking and data analytical skills are required to be able articulate high risks using data insights.
• AI featured auditing skills is preferred.
• Experience in the industries of pharmaceutical, life science, biotech is strongly preferred.
• Experience in manufacturing is strongly preferred.
• Experience in any of the following: risk assessment, data analytics tools is preferred. Excel/Word/PowerPoint capability required.
• Strong sense of ownership on any audit assignment to be able to proactively propose solutions and follow the task through completion.
• Strong sense of urgency to execute assignment with adaptation, agility and prioritization.
• Strong risk-conscious critical thinking skills to be able to execute each step of the audit cycle (planning, scoping, risk-control matrix designing, fieldwork testing, reporting and remediation).
• Ability to work independently, objectively and collaboratively, as required, in a fast-paced and matrixed team environment consisting of internal and external team members, and other assurance business stakeholders.
• Ability to manage multiple projects simultaneously, to meet deadline requirement without compromising quality of deliverables.
• Strong sense of self-awareness to be willing to learn new areas quickly, be growth minded and to accept challenges for continuous improvement.
• Ability to articulate issues and remediations clearly and concisely, supported by factual details, both written and verbal, to different level of management.
• Process-oriented and control-driven with strong analytical skills for analyzing controls, identifying risks and assessing their efficiency and effectiveness.
• Knowledge of U.S. GAAP & IFRS and IIA standards is required.

#Li-LB1

#Li-Hybrid

Legend Biotech is seeking a Manager, Operations Training as part of the Technical Operations team based in Raritan, NJ.

Role Overview

The Manager, Operations Training, will be responsible for managing the training team who lead training activities for the overall plant operation team members who support cGMP Commercial Cell Therapy Manufacturing. This individual will oversee the Training team members in collaboration with department management in Operations and Quality to support personalized cell therapy production through safe and compliant operations according to cGMP requirements. This individual will support the organization door to floor program and ramp-up of commercial production. The role will require technical experience, effective communication, coordination and collaboration across relevant cross functional groups to enable robust production, testing and release of product to patients.

Key Responsibilities

• Leads, directs, coaches and develops a holistic, effective training program for all plant functions and personnel that support daily commercial production.
• Manages training team to plan, coordinate, prepare and deploy training curriculum.
• Perform training assessments for new and updated procedures.
• Oversee and schedule training skill checks and qualifications.
• Support evaluation of appropriate compliance courses.
• Leads and works with training team to manage training requirements for new hires.
• Work collaboratively with functional leads for procedure alignment based on roles.
• Serve as subject matter expert for Compliance & Training systems.
• Oversees onboarding for all new manufacturing operators.
• Knowledge of LMS system.
• Maintain and report quality training metrics.
• Prepares information for internal and external audits.
• Ensure productivity, timeliness, and quality of Change Controls and CAPA implementation.

Requirements

• A minimum of a Bachelor’s Degree in Science; advanced degree preferred.
• A minimum of 5-8 years relevant work and management experience is required. It is preferable that the candidate have experience working within an aseptic manufacturing facility, preferably in training/system applications, quality systems, or learning management systems.
• Knowledge of cGMP regulations and FDA/EU guidance related to manufacturing of cell-based products as well as knowledge of Good Tissue Practices.
• Must be able to manage shifting priorities to meet critical deadlines in a fast paced and dynamic, growing environment, while providing clear direction to team members.
• Strong analytical, problem solving and critical thinking skills and the ability to lead as a change agent to promote flexibility, creativity, and accountability.
• Ability to effectively prioritize and execute tasks in a fast-paced environment.
• Works well in a team-oriented, collaborative environment.
• Demonstrated track record of driving continuous improvement initiatives.
• Proven leadership and team management skills.

#Li-RN1

#Li-Hybrid

Legend Biotech is seeking an Associate Corporate Counsel as part of the Legal team based in Bridgewater, NJ.

Role Overview

The Associate Corporate Counsel will be responsible for the review, drafting, and negotiation of a wide range of commercial agreements, while providing practical, business-oriented legal advice to internal stakeholders. This role will serve as primary legal partner for day-to-day contracting needs of designated business functions and works closely with senior attorneys and cross-functional stakeholders to provide practical, risk-based legal advice while helping to drive efficient contracting processes in a dynamic biotech environment. The position reports to Legend Biotech’s Deputy General Counsel.

Key Responsibilities

• Primary responsibilities include leading the drafting, review, negotiation, and execution of a broad array of commercial, procurement, and other contracts supporting the company’s US and EU commercial, R&D and clinical operations, including master service agreements and related statements of work, manufacturing and supply agreements, quality agreements, confidentiality agreements, consulting agreements (including with healthcare professionals), SAAS agreements, staffing agreements and other contracts.
• Partner with internal stakeholders (e.g. Procurement, Finance, IT, Commercial, R&D, Clinical, Medical) and other subject matter experts to serve as primary legal partner for contracting needs of designated business functions and effectively drive contracts and transactions to conclusion.
• Support contract intake and prioritization in coordination with Legal Operations.
• Support continuous improvement of contracting processes and workflows and assist in the implementation, maintenance, training and enforcement of contract-related policies, procedures and systems.
• Assist in the development and maintenance of standard contract forms, templates and playbooks
• Secondary responsibilities include supporting other members and functions of the Legal Department on ad hoc legal matters and cross-functional special projects, as assigned.

Requirements

• 5+ years of relevant experience, including drafting, reviewing, revising, and negotiating complex agreements and providing legal counsel on contracts and transactions. In-house experience in the life sciences or pharmaceutical industry is preferred.
• J.D. degree from an accredited U.S. law school (or the equivalent); high academic achievement.
• Licensed to practice law in one or more U.S. states; either admission to the New Jersey Bar or eligibility for in-house qualification in New Jersey.
• Knowledge of the legal and regulatory environment applicable to a global life sciences company preferred, including: the Federal Food, Drug and Cosmetic Act, the False Claims Act (and similar state laws), the Anti-Kickback Statute (and similar state laws), and the Foreign Corrupt Practices Act (and similar anti-bribery laws).
• Proficiency with Microsoft Office Suite and digital contract lifecycle management tools.
• Clear and practical communication style.
• Team player with collaborative mindset and willingness to learn in a fast-paced environment.
• Strong organizational skills and ability to manage multiple matters.
• Ability to prioritize work to meet changing needs.
• Strong ability to influence and present complex information to senior leaders.
• Demonstrated success in proactively and independently driving transactions and processes.

#Li-FB1

#Li-Hybrid

Legend Biotech is seeking an Operations Supervisor as part of the Technical Operations team based in Raritan, NJ.

Role Overview

The CAR-T Operations Supervisor is an exempt level position working within Technical Operations team, responsible for directing the daily production of a personalized cell therapy to support both clinical and commercial requirements in a sterile cGMP environment. Job duties will be performed within a team-based environment, on an assigned production shift schedule.

Shift Options Available:

• Sun–Wed, 2nd Shift
• Wed–Sat, 2nd Shift

Key Responsibilities

• Lead and supervise multiple units within the CAR-T process operations (i.e. component preparation manufacturing, MFG support operations, Mock cell, and CAR-T process) according to standard operating procedures and batch records and ensure safe and compliant manufacturing operations according to cGMP requirements.
• Lead the daily start of shift operations meetings, the daily wrap up production meetings and assign individuals their daily production task to execute and ensure compliance and successful completion of work-related tasks.
• Work closely with operations personnel on the production floor to provide guidance and perform production tasks as needed to help the team, in a manner consistent with safety policies, quality systems, and cGMP requirements.
• Support manufacturing investigations, create/revise operational procedures, including manufacturing work instructions, master batch records, forms, and support and manage change controls.
• Work closely with Operations Manager to help oversee the development of production personnel, provide input on personnel performance.
• Build strong partnerships with Manufacturing, Engineering, and Quality to ensure seamless execution of daily production tasks and work as part of a cross-functional team to address production issues as the first point of contact for operators on the production floor.
• Support the development of manufacturing processes, participate in various department projects, and will work with others to drive continuous improvements and efficiencies within cell therapy Technical Operations.
• Job duties performed routinely require exposure to and handling of biological materials and hazardous chemicals.
• Distance visual acuity of at least 20/40 (Snellen) in both eyes without corrective lenses or visual acuity corrected to 20/40 (Snellen) or better with corrective lenses.
• Color Perception both eyes 5 slides out of 8. 

Requirements

• Bachelor’s degree in Science, Engineering or related field or equivalent experience required.
• A minimum of 6 years of operations experience within a cGMP environment in the biotech/biopharma industry. Prior experience in manufacturing, quality, or engineering is required.
• Excellent communication and organizational behaviors skills are required.
• Proficiency with Microsoft Office tools (Word, Excel, PowerPoint, and Outlook) is required.
• Availability to work in a day shift (1st or 2nd shift) is required.
• Knowledge of cGMP regulations and FDA guidance related to manufacturing of cell-based products, and cleanroom behaviors.
• Must exhibit strong Leadership skills and ability to effectively communicate and influence Operations associate and convey information to Management.
• Ability to work independently and successfully, prioritize and manage multiple tasks simultaneously, integrate cross-functional issues and balance competing priorities effectively.
• Must be able to manage shifting priorities to meet critical deadlines in a fast paced and dynamic, growing environment, while providing clear direction to team members.
• Strong analytical, problem solving and critical thinking skills and the ability to lead as a change agent to promote flexibility, creativity, and accountability.
• An ability to build strong partnerships and effectively integrate with external collaborators to drive projects/programs forward in a matrixed environment.
• Clear and succinct verbal and written communication skills with an attention to detail and the ability to follow procedures.
• Experience with Operational Excellence and/or Lean Manufacturing is an asset.
• Ability to accommodate shift work including evenings and weekends as required by the process.
• Ability to accommodate unplanned overtime on little to no prior notice.
• Sufficient vision and hearing capability to work in job environment with physical dexterity sufficient to use computers and document production records
• A working leader who can participate in production runs in critical situations when needed.
• Ability to lift a minimum of 25 lbs. and stand for a long period of time. 

#Li-RN1

#Li-Onsite

Legend Biotech is seeking a Facility Engineer as part of the Technical Operations team based in Raritan, NJ.

Role Overview

This position will be responsible for facilities engineering support, design, and implementation for mechanical systems and equipment, and work order management for cGMP Clinical and Commercial Cell Therapy Manufacturing. This individual will partner with various Technical Operation functions in support of personalized cell therapy production through safe and compliant manufacturing operations according to cGMP requirements. This individual will support the organization in maintaining commercial production at a state-of-the-art cell therapy facility. The role will require proven leadership and expertise that drives effective communication, coordination and collaboration across relevant cross functional groups to enable robust production, testing and release of product to patients.

Key Responsibilities

• Demonstrates professional execution of the planning, development, and implementation of construction and/or repair programs for engineering driven initiatives.
• Serves as SME on engineering design projects; sets project requirements, evaluates compliance with project and engineering standards, and approves final designs and installations.
• Identifies, investigates, and analyzes a wide range of complex facilities, utilities, systems, equipment or manufacturing issues and develops a robust solution for remediation.
• Oversees, reviews, and approves the work of external engineering design and planning consultants; ensures that engineering designs are consistent with contract specifications and all relevant regulations and engineering standards.
• Supports the review of equipment, building, and other job plans within the CMMS for effectiveness, applicability, and compliance. Ensure all equipment is operated and maintained within a validated/qualified/certified state.
• Gathers and analyzes data, blueprints, and reports.
• Supports tracking and achievement of annual maintenance goals and objectives including metric improvement targets. Support continuous improvement activities such as preventive maintenance optimization, risked based asset management programs, and analyze equipment for proper balance of preventive to corrective work order ratio.
• Supports maintenance driven quality events including but not limited to Deviations/Investigations, Out of Tolerances (OOTs), Change Controls, Root Cause Analysis and FMEA’s.
• Ensures regulatory and job training remains current by promptly completing required training.
• Complies with all company and/or site policies and procedures.
• Demonstrates willingness to learn new skills as required.
• Available for other duties as required.
• Ensures site compliance with all local, state and federal regulations including and equivalent to Federal Drug Administration (FDA), Environmental Protection Agency (EPA), Occupational Safety and Health Administration (OSHA), and Drug Enforcement Agency (DEA) as applicable (TSA) Transportation Security Administration.
• Ability to work independently and with minimal guidance/oversight.
• Job duties performed routinely require exposure to and handling of biological materials and hazardous chemicals. 

Requirements

• B.Sc./M Sc. in chemical, mechanical, electrical, industrial engineering or similar field is required
• Minimally 5+ years of experience as a facility engineer or working within an industrial manufacturing or regulated environment is required, ideally has cGMP cleanroom manufacturing experience under aseptic conditions
• Experience with HVAC and building management systems is required
• Experience with SAP and MS Office is required
• Proficiency in English (verbal and written) and strong communication skills
• Experience with a CMMS or similar maintenance management system is preferred
• cGMP manufacturing familiarity is preferred
• Ability to apply engineering principles and techniques to the solution of equipment, buildings, and infrastructure.
• Construction/project management principles. 

Legend Biotech is seeking an Associate Director, Omnichannel Advanced Analytics as part of the Insights & Analytics team based in Bridgewater, NJ.

Role Overview

The Associate Director (AD), Omnichannel Advanced Analytics, is a senior analytics leader responsible for driving insight generation and performance measurement across non‑personal promotion (NPP) and omnichannel engagement. This role builds a rigorous, scalable understanding of which digital and non‑personal tactics work, for whom, and why—enabling data‑driven optimization of channel strategy, content, orchestration, and investment across the customer journey.

The AD partners closely with Commercial, Marketing, Field Operations, and IT to translate complex data into actionable insights, influence strategic decision‑making, and embed advanced analytics into omnichannel planning and execution. This role also provides people leadership and thought leadership within the broader Insights & Analytics organization.

Key Responsibilities

Omnichannel Analytics Strategy & Ownership

• Own and evolve the omnichannel analytics roadmap for NPP, including measurement frameworks, KPI definitions, test‑and‑learn approaches, and standardized performance readouts aligned to brand and marketing decision cycles.
• Establish clear success metrics and accountability for non‑personal and digital engagement, ensuring consistency across brands, channels, and customer segments.
• Serve as the subject‑matter expert on omnichannel and NPP measurement, advising senior Commercial and Marketing leaders on performance interpretation and optimization opportunities.

Measurement of Non‑Personal Promotion & Digital Engagement

• Quantify the effectiveness and impact of NPP tactics, including but not limited to email, web journeys, paid media, webinars/virtual programs, rep‑triggered digital, and other non‑personal touchpoints.
• Assess channel contribution and interaction effects across the customer journey, supporting smarter investment allocation and engagement sequencing.
• Design and execute test‑and‑learn initiatives to evaluate new tactics, content strategies, and orchestration approaches.

Advanced Analytics & Insight Development

• Develop and operationalize advanced analytic assets that enable smarter, more personalized engagement, including:
• Customer segmentation and audience prioritization models
• Response and propensity models (e.g., engagement likelihood, next‑best‑action, or next‑step likelihood)
• Content and channel optimization models (what message works, where, and when)
• Journey analytics, including pathing analysis, drop‑off identification, and sequencing optimization.
• Translate advanced analytics outputs into clear, actionable recommendations for non‑technical stakeholders.

Cross‑Functional Partnership (Commercial & IT) and Leadership

• Partner closely with Commercial, Brand Marketing, Digital, Field Operations, and Market Research teams to align analytics priorities with business objectives and omnichannel strategy.
• Collaborate with IT, Data Engineering, and platform teams to ensure scalable, compliant, and reliable data pipelines, analytic environments, and reporting solutions that support omnichannel use cases.
• Contribute to the broader Insights & Analytics leadership team by shaping standards, best practices, and long‑term capability building in advanced analytics and omnichannel measurement.
• Lead the development of executive‑ready performance readouts, insights summaries, and recommendations for senior leadership.

Decision Making

• The Associate Director will work independently to make decisions related to technical direction, methodologies, approaches on how to address key business questions. Strong collaboration with cross functional teams and robust alignment with Manager will be needed in the identification of Key Business Questions and priorities

Requirements

• Master’s degree (preferred) or bachelor’s degree in business, Analytics, Economics, Data Science, or related field; advanced degree preferred.
• 8–12+ years of experience in pharmaceutical or life sciences analytics, with strong focus on omnichannel, digital, and non‑personal promotion (NPP) measurement.
• Demonstrated experience at the Associate Director or equivalent level, owning analytics products, dashboards, or performance frameworks used by senior leadership and commercial teams.
• Proven expertise in omnichannel and digital engagement analytics, including email, web, media, virtual programs, CRM‑triggered digital, and cross‑channel orchestration.
• Strong understanding of omnichannel measurement and optimization approaches, including segmentation, engagement and response modeling, journey analytics, and channel effectiveness assessment.
• Deep knowledge of commercial pharmaceutical data (sales, claims, CRM, engagement, media, market research) and KPI frameworks.
• Strong leadership and communication skills, with the ability to translate complex analyses into clear, decision‑ready insights for executive audiences.
• Proven cross‑functional collaborator with experience partnering closely with Commercial, Marketing, Digital, Sales Operations, IT, and Data Engineering.
• Experience enabling AI‑ and advanced‑analytics outputs (e.g., segmentation, propensity scores, next‑best‑action) through reporting and insight tools, in partnership with Advanced Analytics teams.
• Demonstrated ability to automate reporting, scale self‑service analytics, and improve speed‑to‑insight while maintaining data quality and governance.

#Li-

#Li-

Legend Biotech is seeking a Manager, Talent Acquisition, Carvykti as part of the Talent Acquisition team based in Somerset, NJ.

Role Overview

The Manager, Talent Intelligence & Sourcing enables HR teams to drive business growth by delivering strategic insights, strengthening global sourcing capabilities, and leading organizational talent strategy initiatives. This role plays a critical part in developing data-informed recruitment strategies, building scalable systems, and fostering strong partnerships with TA teams, HRBPs, Global HR CoEs, and business leaders.

The ideal candidate is highly independent, analytical, and solution-oriented, with deep curiosity for talent movement. This individual will lead efforts to translate complex talent market data into actionable strategies while overseeing key initiatives such as external succession planning and competitive intelligence. The role also includes leadership and development of the sourcing team to enhance Legend Biotech’s global direct sourcing capability.

Key Responsibilities

• Develop talent market intelligence by analyzing talent trends, competitive landscapes, and talent pool availability across key geographies and functions.
• Provide interpretation of market intelligence and assess its implications for hiring strategies, workforce planning, and business competitiveness.
• Monitor global labor market shifts and recommend strategic adjustments to maintain a competitive edge in attracting and retaining top talent.
• Use internal and external data to shape talent acquisition strategies and inform long-term workforce planning.
• Lead the External Succession Planning initiative, evaluating external talent pipelines for critical roles and providing insights to influence leadership succession decisions.
• Own and expand Competitive Intelligence efforts, delivering insights on competitor hiring behaviors, talent movements, organizational structures, and labor market positioning.
• Collaborate with senior HR and business stakeholders to integrate Talent Intelligence insights into broader talent strategies and decision-making frameworks.
• Manage, mentor, and develop the global sourcing team to enhance Legend Biotech’s direct sourcing capability and operational excellence.
• Design and implement scalable sourcing strategies aligned with Legend’s long-term talent needs.
• Partner with regional TA leads and recruiters to strengthen global sourcing capabilities and support high-impact hiring outcomes.
• Leverage talent data and skills analysis to determine optimal sourcing channels and build diverse pipelines of critical talent.
• Embed market insights into recruiter and sourcer workflows, developing training and tools to elevate sourcing effectiveness.
• Build and evolve the infrastructure, tools, and systems required for a scalable, best-in-class Talent Intelligence function.
• Collaborate on workforce forecasting frameworks to enable accurate projections of global hiring needs.
• Develop compelling communication strategies to share market insights with senior stakeholders and influence hiring strategies.
• Educate TA teams and business leaders on talent trends, industry benchmarks, best practices, and emerging TA technologies.

Requirements

• A bachelor’s degree is required in a relevant field.
• Minimum 6 years of relevant experience, Pharmaceutical/Biotech industry experience is preferred.
• Experience in Talent Intelligence, corporate research, talent analytics, consulting, or related strategic roles is preferred.
• Experience managing or mentoring a sourcing or research team is strongly preferred.
• Ability to learn new technology and domains, and quickly understand and apply this knowledge into strategies for Talent Acquisition teams.
• Ability to effectively engage the attention of stakeholders and articulate complex arguments in a polished and professional manner.

#Li-ML1

#Li-Hybrid

Legend Biotech is seeking an Associate Director, Operations Program Lead as part of the Clinical Operations team based in Somerset, NJ.

Role Overview

The Operations Program Lead (OPL), Clinical Operations is accountable for accelerated operational delivery of 1-2 priority cell therapy development programs across all phases. This position is responsible for leading, managing and providing operational oversight for quality delivery within budget across all Legend Pipeline studies for 1-2 assets.

This individual must be able to work and lead in a small, fast-paced environment while also wearing multiple hats at any given time as the needs of the organization change and evolve. This position requires a high-performing contributor with strong leadership and stakeholder management skills. This individual will collaborate with the cross functional team to develop operationally feasible program timelines and identify clinical trial operational risks and develop mitigation strategies to ensure accelerated and cost-efficient quality clinical trial execution.  In addition, the position will ensure program consistency across studies, drive research and operational excellence through process improvement, and represent the clinical trial operation function at internal and external meetings.

This position will oversee 1-2 contractor Clinical Trial Associates (CTA).

Key Responsibilities

Direct end-to-end clinical trial management: 

• Direct end-to-end clinical trial operations activities domestically and globally: i.e. lead and take ownership in all aspects of Study Operations for CAR-T Studies in a matrix environment.
• Responsible for the overall success of the clinical study programs
• Ensures the assigned clinical trials are executed in compliance with FDA and ICH/GCP guidelines/regulations and SOPs. Ensures audit-ready condition of clinical trial documentation including central clinical files.
• Report on all aspects of the study progress at a granular level to stakeholders and senior leaders. Effective, consistent & regular tracking of project (s). Prepare and present project reports as required. Plans, executes, and leads study-specific meetings as needed (e.g., Senior and Mid-level management Study Management Meetings).
• Supports the Development of strategic plans for clinical trial operations, ensuring alignment with the company's overall goals and objectives.
• Collaborate with the cross-functional "core" teams to integrate clinical operations strategies into broader development plans.
• Define project timelines & deliverables, by working closely with the cross-functional core program team for end-to-end execution of clinical trials.
• Collaborates in the preparation and/or review of study-related documents (e.g., study protocols, informed consents and amendments, Study Operations Plan, Monitoring Plan, Pharmacy Manual, Informed Consent, Laboratory Manual, CRF Completion Guidelines, study tools/worksheets and other study-specific documents or manuals).

Clinical Trial Operations Efficiency and optimization:

• The OPL will drive clinical Operations excellence by playing a critical role in Clinical Trial Operations Efficiency and optimization.
• Work with cross-functional teams and external vendors to identify clinical trial operational risks and develop mitigation strategies to ensure quality delivery of the clinical trial to support optimal and efficient clinical trial execution. 
• The position involves working closely with the clinical development team and collaboration with cross-functional teams, including safety, study monitoring and coordinators, data management, biostatistics, bio analytics, tech ops, manufacture, supply chain, regulatory, project management, medical affairs, finance, legal and quality.
• Create and Manage study trial execution RACI to support overall trial execution and operational excellence.
• Contribute to Clinical Operations functional initiatives and institution of best practices.

Resource Management and Direct High Performing team:

• Manage and build a high-performing clinical operations support structure. Duties include hiring, onboarding, training, and development of staff to manage studies.
• Lead, develop and manage study operation manual, new work-streams, SOPs, study template, tracking tools, dashboards to support optimal clinical operation performance.
• Provides study-specific training and leadership to clinical research staff, including CRO, sites and other study personnel to support clinical trial execution and optimization.

Direct and Support Vendor Partnership

• Oversee vendor selection process, management, of Contract Research Organizations (CROs) and vendors involved in clinical trial Operation (CRO, Central Lab, etc).
• Participates in CRO and vendor study related calls and meetings, holds team members accountable for actions, escalates issues and oversees all aspects of daily study operations. Ability to identify issues and risks. Develops and manages mitigations and/or escalate risks appropriately.
• Negotiates vendor contracts / budgets and presents to the executive study team for approval.
• Review and confirm CRO and site payment invoices.
• Lead vendor performance assessment for continuous process improvement
• Management/oversight of external vendor deliverables reports and budgets.
• Collaborate within Clinical Operations and with study leadership team to create preferred vendor list for clinical development.

Leadership Skills

• Has critical thinking skills for problem solving and have the lateral and strategic thinking capacity to drive the study(ies) and understand the upstream, downstream, and lateral implications of decisions that affect study outcomes and timelines.
• Adaptable / flexible, self-starter (willing and able to adjust to multiple demands and shifting priorities; ability to meet day-to-day challenges with confidence and professionalism)
• Excellent team player: willingness and ability to fill functional gaps in a small organization.
• Comfortable multi-tasking in a fast-paced small company startup environment and able to adjust workload based upon changing priorities.

Key Relationships

• The Operations Program Lead in Clinical Operations works closely with the asset Core Team and cross-functional teams such as safety, study monitoring, data management, biostatistics, bioanalytics, manufacturing, supply chain, regulatory, project management, medical affairs, and quality.
• Mentoring and management of a CTA.

Requirements

• Minimum degree requirements of a bachelor’s degree (BA, BS) in scientific or health care discipline. Advance Degree Preferred.
• Oncology and/or Immunology clinical trial operations therapeutic experience required. 10+ years of pharmaceutical, biotech or CRO related/ oncology clinical research experience.
• Experience leading the operational planning and oversight of clinical trials as the point of accountability for operational delivery. (CAR-T trials experience is a plus).
• Demonstrated ability to deliver ambitious trial acceleration timelines within a competitive clinical trial landscape.
• Phase 1 clinical trial operational experience is preferred.
• Experience and knowledge of end-to-end management of clinical trial conduct, knowledge of the pharmaceutical industry and an understanding of clinical drug development, clinical trials operations and FDA/ICH regulatory requirements are essential.
• This position requires experience and leading study/project management to create study project plans, and end-to end-study timelines for execution of clinical trials.
• Demonstrated ability to multi-task and manage high performance demands.
• Excellent organizational skills, ability to manage multiple tasks and meticulous attention to detail.
• CRO/Vendor oversight experience required.
• Project Management (biotech) experience a plus.
• Regulatory authority inspection experience a plus.
• Ability to travel as necessary (approximately 10 – 15 %); both domestically and internationally.
• Effective oral, written and interpersonal communication skills.
• Strong communication and presentation skills.
• Forward and critical thinker.
• SOP development experience preferred.
• Strong organizational and project management skills, and the ability to multitask.
• Computer literacy required (MS word, MS excel, MS PowerPoint and MS Project).
• Excellent working knowledge GCP, FDA and ICH Guidelines.

#Li-AS1

#Li-Hybrid

Legend Biotech is seeking a Principal Scientist, Lentivirus Downstream Process Development as part of the Technical Development team based in Somerset, NJ.

Role Overview

The Principal Scientist, Lentivirus Downstream Process Development, will be a key technical leader responsible for designing, optimizing, and scaling purification processes for lentiviral vectors (LVV) within our innovative pipeline. This role focuses on delivering high-quality vector products to support LVV generation and other advanced cell therapy programs. The successful candidate will drive scientific excellence in downstream processing (DSP)—including clarification, chromatography, TFF, sterile filtration and fill/finish—ensuring processes are robust, scalable, and phase-appropriate for GMP manufacturing. This position demands a blend of hands-on technical mastery and strategic thinking to accelerate timelines while maintaining a patient-focused approach.

Key Responsibilities

• Design and execute highly efficient purification strategies for lentiviral vectors, specifically optimized for CAR-T applications.
• Direct the development and optimization of downstream processes including and not limited to: clarification (depth filtration, centrifugation), chromatography (AEX, SEC, HIC), and Tangential Flow Filtration (TFF) for concentration and diafiltration.
• Provide hands-on training as needed.
• Direct the translation of bench-scale processes to GMP manufacturing, ensuring seamless technology transfer and providing troubleshooting support during clinical production runs
• Lead the execution of study protocols to define operating parameters and performance limits; implement state-of-the-art knowledge management for DSP data.
• Communicate the potential for issues and delays along with solutions and mitigation approaches.
• In collaboration with the Senior Leaders, CMC Project Manager, Project Leader, and other technical leads identify project acceleration opportunities.
• Leverage advanced science and technology to maximize vector recovery, purity, and potency, identifying creative solutions to define unknowns in the viral vector field.
• Guide a team of scientists in the execution of project-specific activities, fostering a culture of transparency, scientific rigor, and continuous improvement.
• Author and serve as a primary reviewer for technical documents, including development reports, SOPs, and CMC sections for regulatory submissions (IND/IMPD).
• Work closely with Upstream Process Development and Analytical Development teams to ensure integrated and holistic process outcomes.
• Tech transfer process to/from other Legend sites or CDMOs
• Resolve conflict and proactively identify/address performance issues.
• Ensure compliance with regulatory requirements. 

Requirements

• Advanced degree (PhD preferred, or MS) in Chemical Engineering, Biomedical Engineering, Virology, Molecular Biology, or a related field.
• 8+ years (PhD) or 10+ years (MS) of experience in process development or manufacturing within a biotech or pharmaceutical setting.
• Deep technical hands-on experience in purification, chromatography, and TFF specifically for viral vectors (Lentivirus preferred)
• Strong understanding of GMP manufacturing requirements and CMC strategies for early-phase clinical trials.
• Deep knowledge and hands-on experiences in cell and lentiviral vector technologies within the current emerging field
• Ability to implement closed-system processes and maximize cost effectiveness
• Strong knowledge in engineering modeling and optimization.
• Excellent leadership, emotional intelligence, and communication skills; ability to maintain composure and strategic focus during challenging development timelines.
• Creative, strategic thinking
• Strong troubleshooting skills
• Preferred experience in developing vector processes tailored for CAR-T generation and systemic delivery
• Preferred experience in handling large scale(>50L) purification process.
• Language: English. Mandarin is a plus. 

#Li-JR1

#Li-Hybrid

Legend Biotech is seeking a Head, Business Operations and Alliance Management as part of the Commercial team based in Bridgewater, NJ.

Role Overview

Reporting directly to the President, Carvykti BU, this role serves as the BU’s Strategy & Execution Lead, driving alignment, execution, and operational effectiveness across Commercial, GMS, Quality, and Medical Affairs. A core responsibility is managing Legend’s strategic alliances—ensuring strong governance, seamless communication, and proactive issue resolution so both organizations deliver on joint CAR‑T objectives.

The role also leads BU‑wide engagement and communication, fostering clarity, connection, and cultural cohesion across global teams. In parallel, it drives capability building, strengthening organizational readiness, talent development, and cross‑functional effectiveness to support Carvykti’s rapid growth and strategic priorities.

Key Responsibilities

Alliance Management:

• Lead governance of current and future alliances, ensuring transparent communication, shared accountability, and timely escalation.
• Coordinate joint steering committees, joint working teams, and governance bodies to ensure compliance with collaboration agreements and delivery on shared milestones.
• Maintain a strong relationship with partner organizations (e.g., Janssen) and serve as a central connective point between Carvykti BU functional stakeholders and alliance partners.
• Proactively identify risks, misalignments, or emerging strategic opportunities within collaborations and drive resolution or acceleration initiatives.
• Ensure open communication channels across both organizations and consistent partnership health tracking.

Engagement & Communication:

• Drive engagement initiatives and forums - town halls, BU business reviews, culture initiatives, leader communications, and cross‑functional alignment sessions.
• Serve as a strategic advisor to the BU President on messaging, engagement cadence, and organizational pulse.
• Design and lead BU‑level internal communications strategy, ensuring clarity, transparency, and alignment from the President through LT‑1 and field/operational teams.

Innovation & Strategy Acceleration:

• Partner with BU President & LT to shape and drive BU strategic initiatives, including transformation, digital capability scaling, operational innovation, and cross‑functional initiatives.
• Monitor industry trends (CAR‑T evolution, regulatory updates, partnership models) and translate insights into BU priorities.

Capability Building:

• Support BU‑wide capability strategy (technical, leadership, and operational), to ensure teams are equipped for current and future needs across Commercial, GMS, Quality, and Medical Affairs.
• Build mechanisms to measure capability maturity and organizational effectiveness.
• Partner with HRBP, OD, and Functional Heads to design learning ecosystems and talent acceleration pathways.
• The Head, Business Operations and Alliance Mgmt. exercises independent decision-making authority across strategic and operational domains, including project scope, timelines, resource allocation, and vendor selection. Decisions related to significant budget changes, strategic shifts, or major collaborations require higher-level approvals. This role is expected to proactively identify issues, propose solutions, and guide cross-functional execution with minimal oversight.

Requirements

• Advanced degree (MBA, MS) preferred; background in cell therapy, biotech, strategy, or operations strongly desirable.
• 10+ years’ in Pharma / Biotech with experience in alliance management, strategy execution, business operations and cross-functional leadership.
• Demonstrated success managing high‑complexity external partnerships and governance structures.
• Experience working with or leading within matrix organizations across Commercial, GMS, Quality, and Medical Affairs is highly desirable.
• Proven track record in driving organizational capability building, communication strategies, or enterprise‑level initiatives.
• Strong written and verbal communication skills; executive‑level presence.
• Strategic systems thinker with ability to distill complexity and drive clarity.
• Exceptional stakeholder management and influence.
• Strong program management, change management, and problem‑solving capability.
• High agility, ability to manage ambiguity, and proactive issue resolution.
• Culturally intelligent and globally collaborative.

#Li-JK1

#Li-Hybrid