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Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.
About This Role
Axsome Therapeutics is seeking a Specialty Account Manager (SAM) to execute commercial activities for assigned geographies, establish relationships with customers, and ensure successful promotion of AUVELITY for major depressive disorder in adults and potential future indications. This role is field-based and will require gaining access to customers in a clinic or hospital setting while also maximizing the ability to engage through digital channels.
SAMs will be responsible for product performance at a territory level and expected to be a disease category expert and product champion. The SAM will provide account management support and exhibit business knowledge of the local landscape to assess key stakeholders plus future trends within the marketplace.
Job Responsibilities and Duties include, but are not limited to, the following:
Qualifications / Requirements
Salary & Benefits
The anticipated salary range for this role is $100,000 - $150,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.
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Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.
About This Role
Axsome Therapeutics is currently searching for a field based Long-Term Care (LTC) Specialty Account Manager (SAM) to drive LTC commercial activities for an assigned geography by executing marketing strategies to ensure a successful launch and make a meaningful difference through the execution of commercial activities.
SAMs will be responsible for product performance at a territory level and expected to be a disease state expert, product champion and an account specialist. The SAM will provide account management support and exhibit business knowledge of the local landscape to assess key stakeholders plus future trends within the marketplace.
Job Responsibilities and Duties include, but are not limited to, the following:
Qualifications / Requirements
Salary & Benefits
The anticipated salary range for this role is $100,000 - $150,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.
Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.
Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.
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If you've worked alongside hardware teams, you know the damage that results from a missed change request or critical context that was never relayed to the right person. Reflow exists to close that gap. We're building the first AI-powered platform built for hardware product development, one that listens across the tools teams already use, maintains a structured picture of every program, and proactively coordinates across disciplines when things inevitably change.
This is an early role for a hands-on AI engineer to design and build the agents at the core of our platform, backed by a parent company with deep roots in engineering and manufacturing. You'll own the AI systems that set our product apart: agents that understand hardware workflows, anticipate problems, and take action on behalf of engineering teams.
We're looking for an AI engineer who works equally well in applied research and production software. You've shipped LLM-powered agent systems to real users, you have strong intuitions about prompt engineering, tool use, and orchestration patterns, and you keep up with a field that changes fast. You're comfortable evaluating new frameworks, models, and techniques on short cycles and making pragmatic build-vs.-adopt decisions as the landscape shifts.
We currently use LangChain's DeepAgent framework for our agent orchestration, but every layer of our AI stack is open to change. The right person for this role understands how agent systems work under the hood, not just one framework's abstractions, and can adapt as better tools and approaches emerge.
This senior engineer will work alongside our engineering team and head of product to build, optimize, and operate the AI agents that give users proactive coordination, risk surfacing, status summaries, and AI-generated deliverables. The role is hands-on. You'll write code daily while contributing to AI architecture decisions and helping define how we evaluate and evolve our agent capabilities over time.
Your day-to-day responsibilities will include:
Must Have:
Highly Valuable:
Real Impact: The opportunity to build purpose-built tooling for an entire industry that has never had it
Customer Access: Direct exposure to hundreds of real hardware projects annually through Re:Build's engineering and manufacturing companies
Technical Growth: Hands-on work at the frontier of applied AI, solving novel agent design challenges with real-world feedback loops
Autonomy: Backed by Re:Build while operating with startup independence
Benefits: Full health/dental/vision, bonus program, generous 401K, paid time off, annual learning stipend
Equity & Growth: Participation in Re:Build's LTIP equity program and opportunity for founder equity in potential spin-out
Location: Remote-first, with preference for candidates in Boston, Seattle, Los Angeles, or other cities with Re:Build offices
Compensation: Base salary range of $143,000 to $215,000 with performance bonus and long-term incentive plan offered. Potential equity stake under independent spinout scenario.
Please note this role is restricted to US citizens or lawful permanent residents only due to exposure to export controlled information.
Re:Build Manufacturing is a growing family of industrial and engineering businesses combining enabling technologies, operational superiority, and strategic M&A to build America's next generation industrial company. At Re:Build we deploy deep expertise in engineering, operations management, and technology to supercharge the performance of our member companies. We harness deep professional expertise and a candid, principled operating culture to drive differentiated outcomes. Ours is a fast-paced environment where individuals can stretch and be challenged to pursue their fullest potential.
Re:Build was founded to pioneer a profitable model for the revitalization of US manufacturing. We've assembled a powerful set of complementary capabilities and lines of business that enable us to pursue a wide range of end markets. Our acquired businesses are grounded in build-to-print and by-the-hour engineering and design services, and we're using their combined expertise to migrate to increasingly sophisticated program development and production, as well as the generation of our own products. Our unique set of capabilities lend themselves to highly complex systems and products, and we offer customers a range of services including product and systems design, automation, fabrication, assembly, and large volume contract manufacturing. Our customers span a wide array of industries including aerospace, defense, mobility, healthcare, pharma, biotech, clean tech, chemicals, energy, lifestyle, food production, and industrial equipment.
Re:Build Manufacturing is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, marital status, parental status, cultural background, organizational level, work styles, tenure and life experiences. Or for any other reason.
Re:Build is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or an accommodation due to a disability, you may contact us at accommodations.ta@ReBuildmanufacturing.com or you may call us at 617.909.6275.
Ready to apply?
Apply to Re:Build Manufacturing
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The Opportunity
If you've worked alongside hardware teams, you know the damage that results from a missed change request or critical context that was never relayed to the right person. Reflow exists to close that gap. We're building the first AI-powered platform purpose-built for hardware product development, one that listens across the tools teams already use, maintains a structured picture of every program, and proactively coordinates across disciplines when things inevitably change.
This is a ground-floor opportunity for a hands-on frontend engineer to shape the user experience of a high-potential product with the support of a parent company leading innovation in engineering and manufacturing.
Who We're Looking For
We're seeking a frontend engineer who cares deeply about building interfaces that are fast, intuitive, and delightful. The ideal candidate has shipped production React applications and has strong opinions on component architecture and design systems. You should already be using AI coding tools like Cursor, Copilot, or Claude to accelerate your work, with excitement about building the product that finally replaces the spreadsheets and status meetings that hardware teams have been stuck with for decades.
This senior engineer will work alongside our engineering team and head of product to build the interfaces through which users manage structured engineering artifacts (requirements, project plans, dependencies), interact with ambient AI agents, and get real-time transparency into project health across disciplines. The role is hands-on - you will be coding daily while contributing to frontend architecture decisions and helping grow the design system as we scale.
What You'll Do
Your day-to-day responsibilities will include:
● Building production-grade React applications with TypeScript
● Developing and maintaining a shared component library
● Building rich interfaces for structured engineering data: requirements with traceability, phase/gate tracking, dependency graphs, task boards with discipline tags, and version-controlled project plans
● Building interfaces for AI agent interactions including streaming chat, proactive coordination alerts, and AI-generated status summaries and deliverables (proposals, SOWs, reports)
● Implementing portfolio-level dashboards for engineering leaders and executives showing cross-project cost, schedule, and risk
● Writing well-tested code with unit and end-to-end tests
● Collaborating with backend engineers on API integration and client SDK usage
● Contributing to frontend architecture decisions, code reviews, and engineering best practices
Technical Requirements
Must Have:
● 5+ years building production web applications, with 3+ years focused on React
● Demonstrated proficiency using AI coding tools (Cursor, Copilot, Claude, etc.) to accelerate development
● Expert-level expertise with React, TypeScript, and modern JavaScript
● Strong experience with component-driven development, design systems, and tools like Storybook
● Proficiency with CSS frameworks (Tailwind CSS preferred) and responsive design
● Experience with modern build tools (Vite, esbuild, or similar)
● Understanding of API integration patterns (REST, OpenAPI, generated clients)
● Ability to balance rapid iteration with maintainable, well-tested code
Highly Valuable:
● Have worked in early-stage 0 to 1 startup environments
● Familiarity with hardware development, engineering workflows, or project management processes
● Experience building UIs for AI/LLM-powered features (streaming responses, chat interfaces, structured AI output)
● Familiarity with headless component libraries (Base UI, Radix, Headless UI)
● Background in data visualization or dashboard-heavy applications
● Understanding of authentication/authorization patterns (OIDC, JWT)
● Experience with end-to-end testing frameworks (Playwright, Cypress)
● Background in B2B SaaS platforms, project management tools, or technical collaboration products
What We Offer
Real Impact: The opportunity to build purpose-built tooling for an entire industry that has never had it
Customer Access: Direct exposure to hundreds of real hardware projects annually through Re:Build's engineering and manufacturing companies
Technical Growth: Hands-on work with cutting-edge AI technologies solving novel technical challenges
Autonomy: Backed by Re:Build while operating with startup independence
Benefits: Full health/dental/vision, bonus program, generous 401K, paid time off, annual learning stipend
Equity & Growth: Participation in Re:Build's LTIP equity program and opportunity for founder equity in potential spin-out
Compensation & Location
Location: Remote-first, with preference for candidates in Boston, Seattle, Los Angeles, or other cities with Re:Build offices
Compensation: Base salary range of $165,000 to $215,000 with performance bonus and long-term incentive plan offered. Potential equity stake under independent spinout scenario.
Please note this role is restricted to US citizens or lawful permanent residents only due to exposure to export controlled information
About Re:Build Manufacturing
Re:Build Manufacturing is a growing family of industrial and engineering businesses combining enabling technologies, operational superiority, and strategic M&A to build America's next generation industrial company. At Re:Build we deploy deep expertise in engineering, operations management, and technology to supercharge the performance of our member companies. We harness deep professional expertise and a candid, principled operating culture to drive differentiated outcomes. Ours is a fast-paced environment where individuals can stretch and be challenged to pursue their fullest potential.
Re:Build was founded to pioneer a profitable model for the revitalization of US manufacturing. We've assembled a powerful set of complementary capabilities and lines of business that enable us to pursue a wide range of end markets. Our acquired businesses are grounded in build-to-print and by-the-hour engineering and design services, and we're using their combined expertise to migrate to increasingly sophisticated program development and production, as well as the generation of our own products. Our unique set of capabilities lend themselves to highly complex systems and products, and we offer customers a range of services including product and systems design, automation, fabrication, assembly, and large volume contract manufacturing. Our customers span a wide array of industries including aerospace, defense, mobility, healthcare, pharma, biotech, clean tech, chemicals, energy, lifestyle, food production, and industrial equipment.
We want to work with people that reflect the communities in which we operate
Re:Build Manufacturing is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, marital status, parental status, cultural background, organizational level, work styles, tenure and life experiences. Or for any other reason.
Re:Build is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or an accommodation due to a disability, you may contact us at accommodations.ta@ReBuildmanufacturing.com or you may call us at 617.909.6275.
Ready to apply?
Apply to Re:Build Manufacturing
Share this job
The Opportunity
If you've worked alongside hardware teams, you know the damage that results from a missed change request or critical context that was never relayed to the right person. Reflow exists to close that gap. We're building the first AI-powered platform purpose-built for hardware product development, one that listens across the tools teams already use, maintains a structured picture of every program, and proactively coordinates across disciplines when things inevitably change.
This is a ground-floor opportunity for a hands-on backend engineer to build the core services and AI infrastructure powering this platform, with the support of a parent company leading innovation in engineering and manufacturing.
Who We're Looking For
We're seeking a backend engineer who ships reliable, well-designed systems and takes ownership of the services they build. The ideal candidate has production experience with Python, FastAPI, and PostgreSQL, and is comfortable building everything from REST APIs to background task pipelines to AI agent infrastructure. You should already be using AI coding tools like Cursor, Copilot, or Claude to accelerate your work, with excitement about building the backend that powers the first AI-native platform for complex hardware development.
This senior engineer will work alongside our engineering team, AI researchers, and head of product to build the services that turn unstructured inputs (call transcripts, emails, documents, datasheets) into structured engineering artifacts (requirements, project plans, dependencies), orchestrate ambient AI agents for proactive coordination, and serve real-time project intelligence to users. The role is hands-on - you will be coding daily while contributing to system design decisions and helping establish backend engineering best practices as we grow.
What You'll Do
Your day-to-day responsibilities will include:
● Designing and implementing RESTful APIs with OpenAPI specs and auto-generated client SDKs using SQLAlchemy and Postgres
● Developing ingestion pipelines using Celery and Redis that connect to tools teams already use (file storage, messaging, email) and extract structured engineering artifacts from unstructured inputs
● Building and extending agentic AI workflows using LangChain, LangGraph, and related frameworks for structured data extraction, risk detection, dependency analysis, and proactive team coordination
● Integrating LLM APIs (Anthropic Claude, OpenRouter) with streaming (SSE), error handling, and cost optimization
● Deploying and operating services on GCP (Cloud Run, Cloud SQL, Memorystore) with Terraform
● Writing well-tested, maintainable code and participating in code reviews to establish engineering best practices
Technical Requirements
Must Have:
● 5+ years building production backend systems, with 3+ years in Python
● Demonstrated proficiency using AI coding tools (Cursor, Copilot, Claude, etc.) to accelerate development
● Strong experience with FastAPI or similar async Python web frameworks
● Production experience with PostgreSQL, including schema design, migrations, and query optimization
● Hands-on experience with task queues and background processing (Celery, Redis, or similar)
● Understanding of API design, authentication patterns (OIDC/JWT), and service architecture
● Experience with containerized deployments (Docker) and CI/CD pipelines
● Ability to balance rapid iteration with maintainable, well-tested code
Highly Valuable:
● Have worked in early-stage 0 to 1 startup environments
● Production experience integrating LLM APIs (Anthropic, OpenAI, etc.) and building AI-powered features with agent orchestration frameworks (LangChain, LangGraph, or similar)
● Hands-on experience with GCP services (Cloud Run, Cloud SQL, Pub/Sub, Secret Manager) and Infrastructure-as-code experience with Terraform
● Experience with data ingestion pipelines and ETL workflows
● Background in B2B SaaS platforms, project management tools, or workflow automation products
● Understanding of hardware development, engineering workflows, or project management concepts (phases, gates, dependencies)
What We Offer
Real Impact: The opportunity to build purpose-built tooling for an entire industry that has never had it
Customer Access: Direct exposure to hundreds of real hardware projects annually through Re:Build's engineering and manufacturing companies
Technical Growth: Hands-on work with cutting-edge AI technologies solving novel technical challenges
Autonomy: Backed by Re:Build while operating with startup independence
Benefits: Full health/dental/vision, bonus program, generous 401K, paid time off, annual learning stipend
Equity & Growth: Participation in Re:Build's LTIP equity program and opportunity for founder equity in potential spin-out
Compensation & Location
Location: Remote-first, with preference for candidates in Boston, Seattle, Los Angeles, or other cities with Re:Build offices
Compensation: Base salary range of $165,000 to $215,000 with performance bonus and long-term incentive plan offered. Potential equity stake under independent spinout scenario.
Please note this role is restricted to US citizens or lawful permanent residents only due to exposure to export controlled information.
About Re:Build Manufacturing
Re:Build Manufacturing is a growing family of industrial and engineering businesses combining enabling technologies, operational superiority, and strategic M&A to build America's next generation industrial company. At Re:Build we deploy deep expertise in engineering, operations management, and technology to supercharge the performance of our member companies. We harness deep professional expertise and a candid, principled operating culture to drive differentiated outcomes. Ours is a fast-paced environment where individuals can stretch and be challenged to pursue their fullest potential.
Re:Build was founded to pioneer a profitable model for the revitalization of US manufacturing. We've assembled a powerful set of complementary capabilities and lines of business that enable us to pursue a wide range of end markets. Our acquired businesses are grounded in build-to-print and by-the-hour engineering and design services, and we're using their combined
expertise to migrate to increasingly sophisticated program development and production, as well as the generation of our own products. Our unique set of capabilities lend themselves to highly complex systems and products, and we offer customers a range of services including product and systems design, automation, fabrication, assembly, and large volume contract manufacturing. Our customers span a wide array of industries including aerospace, defense, mobility, healthcare, pharma, biotech, clean tech, chemicals, energy, lifestyle, food production, and industrial equipment.
We want to work with people that reflect the communities in which we operate
Re:Build Manufacturing is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, marital status, parental status, cultural background, organizational level, work styles, tenure and life experiences. Or for any other reason.
Re:Build is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or an accommodation due to a disability, you may contact us at accommodations.ta@ReBuildmanufacturing.com or you may call us at 617.909.6275.
Ready to apply?
Apply to Re:Build Manufacturing
Share this job
Re:Build Manufacturing is a growing family of industrial and engineering businesses combining enabling technologies, operational superiority, and strategic M&A to build America’s next generation industrial company. At Re:Build we deploy deep expertise in engineering, operations management, and technology to supercharge the performance of our member companies. We leverage deep professional expertise and a candid, principled operating culture to drive differentiated outcomes. Ours is a fast-paced environment where individuals can stretch and be challenged to pursue their fullest potential.
Re:Build was founded to pioneer a profitable model for the revitalization of US manufacturing. We’ve assembled a powerful set of complimentary capabilities and lines of business that enable us to pursue a wide range of end markets. Our acquired businesses are grounded in build-to-print and by-the-hour engineering and design services, and we’re leveraging their combined expertise to migrate to increasingly sophisticated program development and production, as well as the generation of our own products. Our unique set of capabilities lend themselves to highly complex systems and products, and we offer customers a range of services including product and systems design, automation, fabrication, assembly, and large volume contract manufacturing. Our customers span a wide array of industries including aerospace, defense, mobility, healthcare, pharma, biotech, clean tech, chemicals, energy, lifestyle, food production, and industrial equipment.
The Senior Software Engineer is a key technical contributor who designs, develops, and scales cloud-native software solutions that power Re:Build’s digital platforms. In line with The Re:Build Way, this role combines deep hands-on engineering with thoughtful architectural influence, emphasizing ownership, accountability, and long-term system health.
You will collaborate closely with product, design, and cross-functional engineering partners, working in a candid and respectful manner to solve real business problems. You bring a practical, outcome-driven mindset to innovation, thoughtfully integrating emerging technologies such as AI/ML where they add measurable value, and delivering high-quality software that balances speed, reliability, and maintainability.
The ideal candidate thrives in complex environments, approaches challenges with curiosity and discipline, and holds themselves and others to high engineering standards. You champion clean, efficient, and testable code, actively participate in code reviews, and contribute to team growth through mentorship and knowledge sharing. Guided by a mindset of continuous improvement, you stay current with industry trends and help shape Re:Build’s technology roadmap—ensuring our systems remain scalable, secure, and built to endure.
Experience
Programming & Frameworks
Cloud & Infrastructure
AI/ML Integration
APIs & Integration
Security & Compliance
Foundational Knowledge
Agile Practices
Compensation Expectations: Salary Range: $115K to $190K, depending on candidate experience. Additionally you will have an annual cash bonus and long term incentive.
The BIG payoff
We are a company who is going to make a difference in the industries and the communities in which we choose to operate.
Every employee of Re:Build will share ownership in the company and will share in the financial rewards of the success we achieve together, at all levels of the company!
We want to work with people that reflect the communities in which we operate
Re:Build Manufacturing is proud to be an Equal Employment Opportunity and Affirmative Action employer. We do not discriminate based upon race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status, marital status, parental status, cultural background, organizational level, work styles, tenure and life experiences. Or for any other reason.
Re:Build is committed to providing reasonable accommodations for qualified individuals with disabilities in our job application procedures. If you need assistance or an accommodation due to a disability, you may contact us at accommodations.ta@ReBuildmanufacturing.com or you may call us at 617.909.6275.
Ready to apply?
Apply to Re:Build Manufacturing
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