Simtra BioPharma Solutions (Simtra) is a world-class Contract Development Manufacturing Organization, partnering with pharmaceutical and biotech companies to bring their sterile injectable products to market. With facilities in Bloomington, Indiana, US and Halle/Westfalen, Germany, we offer a wide range of delivery systems including pre-filled syringes, liquid/lyophilized vials, diluents for reconstitution, powder-filled vials and sterile crystallization.  

Our product types include biologics and small molecules, cytotoxics, highly potent compounds, diluents for reconstitution and vaccines – which are all directly injected into patients worldwide.  As such, there is a strong emphasis on quality and continuous improvement at Simtra.  We hold ourselves to the highest quality and regulatory standards.

While our primary focus is cGMP manufacturing, we offer many support services including formulation and development, lyophilization optimization, global regulatory support and secondary packaging.  Our teams are driven to help clients scale, innovate and bring life-changing medicines to patients worldwide.

Why join Team Simtra? Because we:

Make it HAPPEN – We bring a growth mindset to every opportunity, developing new skillsets and exceeding our expectations and those of our customers.

Make it TOGETHER – We work as one, respecting each voice and tapping into our unique strengths across teams—so we can solve problems in new ways.

Make it RIGHT – We hold ourselves to a high standard of excellence, fulfilling our commitments to the customer, their patients, and our team members.

Make it COUNT – We take pride in our day-to-day work, knowing the impact we make – taking on challenges big and small to improve patient health.

This role:

We are seeking a highly experienced and strategic Senior Database Administrator (DBA) and enterprise application architect to join our IT team. The ideal candidate will bring over fifteen years of hands-on expertise in Oracle Database Administration, MS SQL Server, and multi-platform enterprise application  environments such as Oracle, SAP, JDEdwards, on different operating systems including Linux/Unix and Windows. This role also requires deep technical knowledge of application architecture, datacenter infrastructure, including networking, virtualization, and enterprise storage systems. The Senior DBA and architect will play a key role in architecting and designing database and infrastructure solutions, providing day-to-day operational support, and leading technical delivery of complex projects to support our enterprise applications.

What you'll be doing:

• Architect and design scalable, secure, and high-performance database solutions across Oracle and MS SQL Server platforms.
• Lead the architecture and integration of database systems with datacenter technologies including networking, virtualization, and storage.
• Provide day-to-day support for production, development, and test database environments, ensuring optimal performance and uptime.
• Collaborate with infrastructure, application, and security teams to align database and datacenter strategies with business goals.
• Lead the technical delivery of database and infrastructure projects, including upgrades, migrations, and consolidations.
• Develop and enforce database standards, best practices, and security policies.
• Perform capacity planning, performance tuning, and disaster recovery planning.
• Troubleshoot and resolve complex issues across database, OS, network, and storage layers.
• Ensure core enterprise applications are performing at optimal speeds and are fully backed up and redundant.
• Mentor junior DBAs and technology managers to serve as a subject matter expert across all IT teams.

Technical Skills & Expertise:

Enterprise Applciations:

• JDEdwards
• Oracle Applications
• D365
• SAP
• PTC
• Siebel
• Salesforce
• Workday
• Other HRIS Platforms

Database Platforms:

• Oracle: 10g, 11g, 12c, 19c
• MS SQL Server: 2008, 2012, 2016, 2019, 2022
• Postgres
• NoSQL Databases
• ODBC
• Reporting Replicas
• Datawarehousing Techniques
• Snowflake
• PL/SQL, T-SQL, SQL performance tuning

Operating Systems:

• Unix/Linux: Solaris 5, AIX, RHEL, CentOS
• Windows Server: 2003, 2008, 2012, 2016, 2019, 2022

Datacenter Technologies:

• Networking: TCP/IP, DNS, DHCP, VLANs, firewalls, load balancers
• Virtualization: VMware vSphere/ESXi, Microsoft Hyper-V, Oracle VM
• Storage: SAN/NAS, RAID, Fibre Channel, iSCSI, NetApp, EMC, Dell EqualLogic

Cloud Technologies:

• AWS
• Azure
• Datalakes
• Data Lakehouses
• Data warehouses

Scripting & Automation:

• Bash, PowerShell, Python (for automation)
• Infrastructure automation tools (e.g., Terraform, preferred)

Preferred Certifications:

• Oracle Certified Professional (OCP)
• Microsoft Certified: Database Administrator
• VMware Certified Professional (VCP)
• Red Hat Certified Engineer (RHCE)

What you'll bring:

• 15+ of experience in life sciences, pharma or biotech
• 15+ years of leadership in technology & architecture
• Ability to travel internationally as necessary.

Physical / Safety Requirements

• Position requires sitting for long hours, but may involve walking or standing for periods of time

In return, you’ll be eligible for[1]:

• Day One Benefits
• Medical & Dental Coverage
• Flexible Spending Accounts
• Life and AD&D Insurance
• Supplemental Life Insurance
• Spouse Life Insurance
• Child Life Insurance
• 401(k) Retirement Savings Plan with Company Match
• Time Off Program
• Paid Holidays
• Paid Time Off
• Paid Parental Leave and more
• Adoption Reimbursement Program
• Education Assistance Program
• Employee Assistance Program
• Community and Volunteer Service Program
• Additional Benefits
• Short and Long-Term Disability Insurance
• Voluntary Insurance Benefits
• Vision Coverage
• Accident
• Critical Illness
• Hospital Indemnity Insurance
• Identity Theft Protection
• Legal and more
• Onsite Campus Amenities
• Workout Facility
• Cafeteria
• Credit Union

[1] Current benefit offerings are in effect through 12/31/26

Disclaimer

This job description is intended to provide the minimum knowledge, skills and abilities necessary to perform the job.  It may not be inclusive of all the duties and responsibilities of the job.  Simtra reserves the right to make modifications based on business requirements.

Equal Employment Opportunity

Simtra is proud to be an equal opportunity employer. Simtra evaluates qualified applicants without regard to race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, protected veteran status, disability/handicap status or any other legally protected characteristic.

Data Privacy

To learn more about Simtra's approach to data privacy, please review the Simtra Recruitment Platform Global Privacy Policy:  https://simtra.com/privacy-policy/

Simtra BioPharma Solutions (Simtra) is a world-class Contract Development Manufacturing Organization, partnering with pharmaceutical and biotech companies to bring their sterile injectable products to market. With facilities in Bloomington, Indiana, US and Halle/Westfalen, Germany, we offer a wide range of delivery systems including pre-filled syringes, liquid/lyophilized vials, diluents for reconstitution, powder-filled vials and sterile crystallization.  

Our product types include biologics and small molecules, cytotoxics, highly potent compounds, diluents for reconstitution and vaccines – which are all directly injected into patients worldwide.  As such, there is a strong emphasis on quality and continuous improvement at Simtra.  We hold ourselves to the highest quality and regulatory standards.

While our primary focus is cGMP manufacturing, we offer many support services including formulation and development, lyophilization optimization, global regulatory support and secondary packaging.  Our teams are driven to help clients scale, innovate and bring life-changing medicines to patients worldwide.

Why join Team Simtra? Because we:

Make it HAPPEN – We bring a growth mindset to every opportunity, developing new skillsets and exceeding our expectations and those of our customers.

Make it TOGETHER – We work as one, respecting each voice and tapping into our unique strengths across teams—so we can solve problems in new ways.

Make it RIGHT – We hold ourselves to a high standard of excellence, fulfilling our commitments to the customer, their patients, and our team members.

Make it COUNT – We take pride in our day-to-day work, knowing the impact we make – taking on challenges big and small to improve patient health.

This role:

The Lead IT Engineer provides strategic oversight and technical leadership across all facets of the organization’s infrastructure—servers, cloud, networking, storage, telephony, and endpoint management—ensuring security and reliability. They will work with both non-validated and validated systems to ensure compliance under GMP/21 CFR Part 11. Acting as the highest-level escalation point, you will architect solutions, define roadmaps, and guide large-scale projects that shape the future of IT operations. This includes working with operational technology, lab systems, and strategic partners to align IT best practices with evolving business requirements. You will lead continuous service improvements, oversee release and change management in ServiceNow, and support a culture of innovation and knowledge-sharing. Success in this role includes exceptional technical leadership, strategic thinking, and stakeholder management to deliver robust, secure, and scalable infrastructure solutions for the enterprise.

Further, this is a pre-management role, with the expectation hat the incumbent develop and refine the skills needed to providing leadership, oversight and management of all Plant information technology solutions and teams.

The responsibilities:

• Act as the final/highest-level escalation point and the point of contact for external vendor escalations for infrastructure support tickets and complex issues, including network outages, major incidents, or system failures. Use ServiceNow to manage incidents, service requests, and changes adhering to established SLAs and ITSM processes and providing professional and quality service.
• Participate and run the Major Incident Management process and coordinate efforts for resolution.
• Collaborate on long-term architecture and technology roadmaps for on-prem and cloud environments (Azure, AWS).
• Conduct capacity planning and performance analyses to inform budgeting, resource allocation, and future investments.
• Evaluate emerging technologies (e.g., IoT, SD-WAN, containerization) for potential implementation in manufacturing and OT contexts.
• Own incident, request, enhancement, knowledge, CMDB, release and change management processes for infrastructure, ensuring compliance with GMP/21 CFR Part 11 and ITIL best practices.
• Oversee patching strategies for both validated and non-validated systems, collaborating with QA/Compliance teams to manage regulated environments.
• Partner with Operational Technology, lab systems, and IoT teams to align manufacturing processes with IT best practices.
• Work with IT Business Analysts, Senior Engineers, and offshore support teams to deliver integrated solutions for critical applications.
• Maintain and improve collaboration and communication systems. Including cisco telephony for IP and non-IP phone systems, conference rooms, Microsoft teams, multi-function printers and secure print.
• Liaise with vendors, consultants, and third-party providers for specialized projects or advanced troubleshooting.
• Implement robust firewall and network segmentation strategies to protect manufacturing networks and lab environments.
• Guide the security posture (SSO, MFA, Zero Trust) in partnership with Information Security teams.
• Continuously evaluate and mitigate infrastructure risks, including vulnerability management and BCP/DR testing.
• Ensure accurate CMDB maintenance and foster knowledge management practices that enhance shift-left efficiency.
• Create advanced dashboards and reports for senior management, highlighting KPIs, trends, and improvement areas.
• Mentor Senior IT Engineers and collaborate with offshore partners to build a high-performing, cross-functional team.
• Encourage continuous learning and skill development, cultivating a culture of innovation and best-practice adoption.
• Ensure all Infrastructure and Operations efforts are completed on-time and with quality which includes managing and enhancing monitoring and alerting, backup and recovery, patching, and performing analysis to build reliable, resilient, secure, and scalable systems.
• Lead by example with documentation, compliance, and communication standards, reinforcing knowledge-sharing across the organization.
• Oversee major initiatives to improve reliability, performance, and scalability across on-prem, cloud, and hybrid infrastructures.
• Identify improvement opportunities in processes, automations (e.g., Infrastructure as Code), and advanced monitoring solutions.
• Drive collaboration between corporate IT, OT, lab systems, and offshore partners for seamless end-to-end service delivery. 

 Qualifications:

• Bachelor’s or master’s degree in computer science, IT, or related field; or equivalent experience
• 5–8+ years of experience in progressive IT infrastructure roles, with 2+ years in a leadership or senior engineering capacity.
• Extensive experience in regulated (GMP/21 CFR Part 11) environments, overseeing validated and non-validated systems preferred.

Technical Skills:

• Expert-level knowledge of server/virtualization (Windows, Linux, VMware/Hyper-V), networking (firewalls, LAN/WAN, SD-WAN), and cloud architectures (Azure, AWS).
• Advanced understanding of database, storage (SAN/NAS), backup/DR solutions, and telephony.
• Proven track record of managing complex security postures, vulnerability remediation, and identity solutions (SSO, MFA).
• Proficiency in ServiceNow or similar ITSM platforms, leveraging advanced features (dashboards, automation, CMDB).
• Strong knowledge and understanding of Operational Technology setups, lab systems, and compliance requirements in a manufacturing context.
• Proficiency in the following technical stacks – Cisco (wireless, switching), Fortinet (firewalls/SDWAN), Ubiquiti (wireless, switching), Windows Server, Hyper-V/SCVMM, VMware, MS SQL, Azure IaaS/PaaS, M365, and Veeam.

Soft Skills:

• Exceptional strategic thinking and architecture design capabilities.
• Strong leadership and mentorship skills, able to motivate and develop high-performing engineering teams.
• Excellent communication and stakeholder management skills, adept at conveying technical details to executive audiences.
• Demonstrated ability to handle major incidents and make critical decisions under pressure.
• A self-starter who remains current with industry trends, tools, and best practices.

 Additional requirement(s):

• Availability to participate in 24/7 on-call rotation.
• Ability to work on-site in a regulated pharmaceutical/manufacturing setting, adhering to all compliance and safety standards.
• Willingness to occasionally travel to other sites or data centers as needed.
• Desire to progress into a management role 

In return, you’ll be eligible for[1]:

• Day One Benefits
• Medical & Dental Coverage
• Flexible Spending Accounts
• Life and AD&D Insurance
• Supplemental Life Insurance
• Spouse Life Insurance
• Child Life Insurance
• 401(k) Retirement Savings Plan with Company Match
• Time Off Program
• Paid Holidays
• Paid Time Off
• Paid Parental Leave and more
• Adoption Reimbursement Program
• Education Assistance Program
• Employee Assistance Program
• Community and Volunteer Service Program
• Employee Ownership Plan
• Additional Benefits
• Short and Long-Term Disability Insurance
• Voluntary Insurance Benefits
• Vision Coverage
• Accident
• Critical Illness
• Hospital Indemnity Insurance
• Identity Theft Protection
• Legal and more
• Onsite Campus Amenities
• Workout Facility
• Cafeteria
• Credit Union

[1] Current benefit offerings are in effect through 12/31/26

Disclaimer

This job description is intended to provide the minimum knowledge, skills and abilities necessary to perform the job.  It may not be inclusive of all the duties and responsibilities of the job.  Simtra reserves the right to make modifications based on business requirements.

Equal Employment Opportunity

Simtra is proud to be an equal opportunity employer. Simtra evaluates qualified applicants without regard to race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, protected veteran status, disability/handicap status or any other legally protected characteristic.

Data Privacy

To learn more about Simtra's approach to data privacy, please review the Simtra Recruitment Platform Global Privacy Policy:  https://simtra.com/privacy-policy/

Barbaricum is seeking a Cyber SME/Cyber Architect to support the design, implementation, and maintenance of mission-critical IT infrastructure. This role will support system operations, integration, and performance optimization in complex operational environments. Supports exercises in the Greater Indiana Area with 10–25% travel between Camp Atterbury and Muscatatuck Training Center.

Responsibilities:
•    Install, configure, and maintain enterprise systems and infrastructure.
•    Support system integration and configuration management activities.
•    Monitor system performance and troubleshoot technical issues.
•    Implement system updates, patches, and security controls.
•    Support system documentation and configuration management.
•    Collaborate with network, security, and engineering teams.

Required Qualifications:
•    Active DoD Secret Clearance
•    Bachelor’s degree in information technology, computer science, or related field.
•    Experience administering enterprise IT systems and infrastructure.
•    Knowledge of operating systems, virtualization, and enterprise IT architecture.
•    Experience troubleshooting and resolving system performance issues.

Preferred Qualifications:
•    Experience supporting DoD or government IT systems.
•    Certifications such as Security+, Network+, or similar.
•    Experience supporting cloud or hybrid environments in the Greater Indianapolis area.

How You'll Make an Impact: 

As a Senior Fullstack Engineer on the Distribution Team, you'll be instrumental in developing and enhancing the products that connect Cloudbeds' ecosystem to the world's largest distribution channels. You'll architect scalable solutions using modern technologies, contribute to our microservices migration, and ensure our platform delivers exceptional performance and security for thousands of properties worldwide. Your work will directly impact how hotels reach guests through integrations with major platforms like Booking.com, AirBnb and beyond.

Our Distribution Team:

We're the bridge connecting properties to the global travel ecosystem. Our team tackles complex integration challenges that directly impact revenue for thousands of hotels worldwide, from building rock-solid connections with major OTAs to ensuring every booking flows seamlessly and securely. We balance innovation with pragmatism: migrating legacy systems to modern microservices while maintaining the reliability our customers depend on. If you thrive on solving hard technical problems with real business impact and love the challenge of both building greenfield features and refactoring legacy code, you'll feel right at home here.

What You Bring to the Team:

• Design and implement robust backend features and improvements using PHP, with a strong focus on performance optimization and scalability for our distribution platform
• Build intuitive frontend experiences using React and Vue, ensuring seamless user interactions across the Cloudbeds ecosystem
• Architect secure solutions for handling financial transactions and sensitive personal data, applying security best practices throughout the development lifecycle
• Write clean, well-tested, and well-documented code with comprehensive test coverage (unit, integration, end-to-end) to maintain high quality standards
• Lead technical discussions on complex concepts and requirements with both technical and non-technical stakeholders, driving alignment on backend and frontend architecture decisions
• Contribute to our ongoing initiative to migrate core platform components into microservices, helping shape the long-term technical vision
• Re-architect and refactor existing legacy systems to align with modern standards and project requirements, demonstrating ownership and commitment to continuous improvement
• Mentor team members through pair programming and code reviews, promoting best practices that elevate code quality and team processes
• Collaborate with cross-functional teams to plan, build, and ship high-quality features that delight our global customer base

What Sets You Up for Success:

• 5+ years of PHP web application software engineering experience
• 5+ years of experience with JS frameworks, Vue.js and React are preferred
• Solid experience with modern JavaScript/TypeScript
• Strong hands-on experience with Docker and containerized development workflows
• Demonstrated expertise in performance optimization and expert knowledge of relational databases, indexing, and searching technologies
• Strong understanding of security considerations, particularly for applications handling financial transactions and personal data
• Experience with test automation across all levels (unit, integration, end-to-end) and a passion for quality-driven development
• Proven track record of taking ownership of projects and delivering results independently
• Business-level English fluency (verbal and written) and excellent communication skills for collaborating across a globally distributed, remote-first team

Bonus Skills to Stand Out:

• Experience designing and building microservices and/or micro-frontends
• Hands-on experience with PHP frameworks (CodeIgniter, CakePHP, Laravel, Symfony)
• Cloud and infrastructure experience with Kubernetes, AWS, Terraform, and Argo CD
• Experience working with event-driven architectures and messaging systems (e.g., Kafka)

Compensation: Depending on your skills and experience, you can expect your annual compensation to be between $145,000 - $165,000

At Champion, we believe that the biggest growth catalyst doesn't lie outside, but within. It's not about more, but about untapping the potential from opportunity that already exists — from within your champions and yourself. As a product and a company, we're set on creating deeper partnerships with organizations and their champions so every person can do more, together.

But Champion doesn't just represent business growth. It represents individual and professional growth. Champion embodies our passion to build and cultivate an excellent company where we celebrate and advocate for what makes each team member a champion. We seek members with winning mindsets, creative and diverse thinking, and the desire to be all in.

Who We Are Looking For

As an early-stage startup, you will be part of the starting lineup — and at this level, you'll help define it.

We're looking for a seasoned Senior or Principal Engineer who brings deep technical expertise, strong architectural instincts, and the leadership presence to raise the bar across the entire engineering organization. You'll be a driving force behind our product, shaping both the technical vision and the culture of the team. We have great momentum with our initial product and a growing customer base — now we need someone who can help us scale intelligently and build for what's next.

What You'll Do

• Architect and lead the design of scalable, high-performance systems across our full stack using TypeScript, Node.js, Python, and React
• Drive technical strategy — evaluate tradeoffs, establish patterns, and make foundational decisions that will shape the platform for years to come
• Own complex, ambiguous problems end-to-end, from discovery through delivery, with minimal direction
• Design and build data infrastructure — data pipelines, warehousing solutions, and the data models that power product analytics and customer insights
• Develop and integrate ML-powered features where applicable, including model evaluation, feature engineering, and productionizing models at scale (strong plus)
• Mentor and grow engineers at all levels through code reviews, design discussions, and technical guidance
• Partner cross-functionally with Product and Design to refine roadmap items into well-scoped, high-impact work
• Leverage AI-powered developer tooling (e.g., Claude Code, GitHub Copilot) to accelerate delivery, improve code quality, and set a standard for how the team integrates these tools into everyday workflows
• Champion (pun intended) extensible, secure, and observable software patterns across the organization

What You'll Need

• 8+ years of professional software engineering experience, with a track record of leading technical initiatives on high-performing teams
• Deep proficiency in TypeScript, Node.js, React, Vu, and/or Python; strong ability to ramp quickly on new technologies as the stack evolves
• Demonstrated experience architecting and operating distributed systems, microservices, and REST APIs at scale
• Strong hands-on experience with Cloud platforms (AWS or Google Cloud), including infrastructure design and cost-conscious scaling
• Advanced SQL proficiency and experience with relational database design, query optimization, and schema evolution
• Experience with data warehousing and data pipeline development (e.g., Snowflake, BigQuery, dbt, Airflow) — strong plus
• Exposure to machine learning workflows — feature engineering, model serving, or MLOps — in a production environment (strong plus)
• Excellent communication skills with the ability to influence technical and non-technical stakeholders in a remote-first environment
• A strong testing discipline, including unit, integration, and end-to-end testing strategies

Additional Information

• $140k – $180k annual salary based on experience
• Comprehensive benefits, including healthcare, dental, and vision coverage for employees
• Meaningful equity grants
• Monthly equipment stipend to cover laptop, monitor, and any software or equipment you may need
• Hybrid or fully remote position
  • Local team members (preferred) come into the office approximately 2x per week (flexible)
  • Remote team members travel to the office approximately 2–4x per year for training, corporate events, or other business needs

Values We Live By

Go On Offense — We champion a culture of experimentation and adaptation, unafraid to maneuver as circumstances evolve, and we play to win.

Be Better Than Yesterday — In our arena of growth, every day is a new game.

Get Curious, Not Critical — We learn in a deeper, more meaningful way, driving greater impact.

Check Your Ego at the Door — We are curious, collaborative, open to feedback, and all in to do whatever it takes. The best idea wins, no matter who it comes from.

One Team, One Goal — We believe and understand that we all impact the collective goal.

Champion is an equal-opportunity employer, and we value diversity at our company. We don't discriminate based on race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.