Forge Your Future with Us:

At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you’re driven by purpose and excited to make a tangible impact, this is where your journey begins.

Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won’t just watch innovation happen — you’ll be part of it. Whether you’re scaling AAV manufacturing, collaborating on cutting-edge therapies, or supporting complex technical projects, you’ll play a key role in bringing hope to patients with genetic diseases.

What sets Forge apart is our culture of H.O.P.E. We are hardworking, showing up each day with determination and grit. We are open, creating a space where ideas flow freely, and every voice is valued. We are purpose-driven, with every task directly tied to changing lives. And we are engaged, energized by the challenges we face and the milestones we achieve together.

At Forge, your growth matters. We’re committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement. Our people are our greatest investment, and we’re proud to see team members grow with us.

If you’re ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself.

About The Role

The Scientist I (Statistics) supports the application of statistical methods to bioanalytical assay development, qualification, and validation activities within the Quality Control and Analytical Development functions. This role applies established statistical approaches to ensure data integrity, regulatory compliance, and accurate interpretation of analytical results. The Scientist I collaborates cross-functionally to support experimental design, data analysis, and documentation, contributing to the advancement of gene therapy programs.

What You'll Do:

· Apply established statistical methods to support development, qualification, and validation of bioanalytical methods (e.g., potency assays, ddPCR workflows)

· Perform statistical analyses for assay validation, including linearity, accuracy, precision, and detection limits

· Support stability studies through trend analysis, control charting, and regression modeling

· Assist in data review, interpretation, and troubleshooting for assay development and optimization activities

· Contribute to statistical analysis plans (SAPs), validation protocols, technical reports, and regulatory documentation

· Collaborate with cross-functional teams (QC, Analytical Development, Process Development, Regulatory)

· Support investigations, deviations, and root cause analyses with statistical input

· Assist in developing and maintaining data trending and reporting tools

· Ensure compliance with regulatory requirements (e.g., ICH, USP, FDA)

· Communicate statistical findings clearly to stakeholders

What You'll Bring:

• Ph.D. in Statistics or related field (or Master’s with relevant experience)

• 1–3 years of relevant experience in a biopharmaceutical, biotechnology, or analytical laboratory setting

• Experience with statistical software (JMP, SAS, R, Python)

• Strong analytical and problem-solving skills

• Effective written and verbal communication skills

• Ability to work independently within defined frameworks and collaborate across teams

Preferred Skills

• Familiarity with nucleic acid-based assays (e.g., ddPCR, qPCR)

• Experience with protein or cell-based assays (e.g., ELISA, flow cytometry)

• Experience in GxP-regulated environments

• Exposure to assay validation and stability studies

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned.

Work Environment and Physical Demands  

This position is performed in a temperature-controlled laboratory or office environment and requires regular standing, hand manipulation, and use of laboratory equipment. The role may involve lifting or moving materials up to 25 pounds and occasional reaching or handling at various heights. Appropriate personal protective equipment (PPE) must be worn when working with chemicals, biological materials, or in controlled environments.

Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.

We’ve Got You Covered: 

At Forge Biologics, we believe our people deserve to be taken care of – in and out of the workplace. We’ve built a comprehensive compensation and benefits package designed to help you thrive, grow, and feel valued every step of the way:

Health from day one

• Health, dental and vision insurance start your first day – with 90% of premiums covered for you and your family.

Time to recharge

• A competitive paid time off plan – because rest fuels innovation.
• 12 weeks of fully paid parental leave so you can focus on family when it matters most.

Rewarding your impact

• Annual bonus opportunities for all full-time team members.
• 401(k) with company match to help you plan for the future.
• Special employee discounts, including childcare and dependent care savings.

Your wellness, supported

• Onsite fitness facility at The Hearth.
• Mental health counseling and financial planning services through our Employee Assistance Program.
• Employer-paid short and long-term disability coverage to protect your peace of mind.

Fuel for your workday

• A fully stocked kitchen with free snacks and beverages – we keep you energized and ready for what’s next.

Grow with us

• Ongoing professional development resources, training, and mentorship programs to help you build your care and grow within Forge.

About impact.com
impact.com is the world’s leading commerce partnership marketing platform, transforming the way businesses grow by enabling them to discover, manage, and scale partnerships across the entire customer journey. From affiliates and influencers to content publishers, brand ambassadors, and customer advocates, impact.com empowers brands to drive trusted, performance-based growth through authentic relationships. Its award-winning products - Performance (affiliate), Creator (influencer), and Advocate (customer referral) - unify every type of partner into one integrated platform. As consumers increasingly rely on recommendations from people and communities they trust, impact.com helps brands show up where it matters most. Today, over 5,000 global brands - including Walmart, Uber, Shopify, Lenovo, L’Oréal, and Fanatics - rely on impact.com to power more than 350,000 partnerships that deliver measurable business results.

Your Role at impact.com:

We're seeking a Senior Data Scientist to serve as an embedded Data Scientist within our Programmatic Experience Group. You'll own the design and deployment of machine learning models that optimize yield, pricing, and inventory allocation at scale — sitting at the intersection of data science, platform engineering, and marketplace economics.

This is a high-craft, high-ownership individual contributor role. You'll work end-to-end: architecting the data pipelines that feed your models, engineering the features that drive performance, and deploying real-time inference systems that make decisions at speed. Your work directly determines how effectively Impact's programmatic marketplace balances advertiser performance with publisher monetization — making this one of the highest-leverage technical roles in the business.

You'll collaborate closely with Product, Data Science, and Programmatic Delivery Engine Engineering, but you operate with significant autonomy. You're expected to bring both the modeling rigor of a data scientist and the production instincts of an ML engineer — and to be genuinely excited about both.

What You'll Do:

Yield Optimization & Pricing Models

• Design and deploy ML models that optimize auction pricing, bid shading, floor price setting, and yield across Impact's programmatic inventory.
• Build and iterate on real-time pricing algorithms that balance short-term revenue efficiency with long-term publisher and advertiser health.
• Develop and maintain feedback loops that allow pricing models to adapt to shifting market conditions, inventory mix, and demand patterns.
• Quantify the revenue impact of pricing model improvements; communicate tradeoffs between yield maximization, fill rate, and partner ROI to stakeholders.

Inventory Allocation & Supply Optimization

• Own ML-driven inventory allocation logic: routing, pacing, and matching supply to demand across partner segments, deal types, and campaign objectives.
• Build models that forecast inventory availability, demand curves, and clearing prices to support proactive allocation decisions.
• Identify and address inefficiencies in inventory utilization — including unsold inventory, suboptimal deal matching, and allocation imbalances across the publisher base.

Data Architecture & Feature Engineering

• Design and own the data infrastructure that feeds programmatic models: event pipelines, feature stores, training datasets, and real-time feature serving.
• Engineer high-signal features from auction logs, bid stream data, user signals, contextual attributes, and historical performance — at the scale of programmatic data volumes.
• Build robust data pipelines with production-grade standards: reliability, observability, versioning, and efficient reprocessing.

Real-Time Inference & Production ML

• Deploy models to production real-time inference environments; own latency, reliability, and throughput requirements for auction-time decision-making.
• Build monitoring systems that track model performance, data drift, and system health in production; define alerting thresholds and retraining triggers.
• Partner with MLOps and Platform Engineering to ensure scalable, low-latency serving infrastructure meets SLOs under high-volume auction traffic.
• Own the full model lifecycle: training, evaluation, deployment, A/B testing, and iteration.

Experimentation & Performance Measurement

• Design and execute rigorous A/B and holdout experiments to measure the causal impact of model changes on yield, fill rate, advertiser performance, and publisher revenue.
• Build evaluation frameworks that go beyond offline metrics — validating model behavior in live auction environments where feedback signals are delayed or noisy.
• Translate experimental results into clear business narratives; present findings and recommendations to Product and business stakeholders.

Self-Learning Systems & Feedback Loops

• Research and implement adaptive, self-learning components within the programmatic stack — including contextual bandits, reinforcement learning signals, and online learning approaches where appropriate.
• Design feedback mechanisms that close the loop between auction outcomes, model updates, and system behavior; reduce reliance on manual tuning and rule-based overrides.
• Stay current with advances in programmatic ML, auction theory, and online optimization; evaluate applicability to Impact's specific marketplace dynamics.

Cross-Functional Collaboration

• Serve as the primary ML technical partner for the Rubicon product and engineering teams; translate business requirements into modeling approaches and communicate technical tradeoffs clearly.
• Collaborate with Data Science peers on shared infrastructure, modeling standards, and cross-domain feature reuse.
• Document models, architectures, and experimental findings to a standard that enables review, replication, and knowledge transfer across teams.

What You Bring:

Required

• Experience: 5+ years in data science, ML engineering, or quantitative research, with at least 2+ years building and deploying ML models in programmatic advertising, ad tech, marketplace optimization, or a closely related domain (e.g., real-time bidding, dynamic pricing, auction systems).
• Programmatic & marketplace depth: Demonstrated understanding of programmatic auction mechanics (RTB, header bidding, floor pricing, deal types, bid shading) and how ML can be applied to optimize outcomes across the supply-demand stack.
• Production ML engineering: Proven ability to take models from prototype to production independently — including real-time inference, monitoring, retraining pipelines, and SLO ownership.
• Data architecture: Experience designing and building data pipelines, feature stores, and training infrastructure for high-volume, low-latency ML systems.
• Technical skills:
• Strong Python and SQL; proficiency with ML libraries (scikit-learn, XGBoost, LightGBM, PyTorch/TensorFlow) and large-scale data tools (Spark, Kafka, or equivalent streaming/batch frameworks).
• Experience with real-time feature serving and low-latency model deployment (REST APIs, gRPC, or streaming inference).
• Familiarity with production ML workflows: model versioning, drift monitoring, A/B testing, evaluation, and retraining.
• Experience processing and modeling at programmatic data scale: high-cardinality auction logs, bid stream data, impression and click events.
• Experimentation rigor: Strong grasp of causal inference and experiment design in online, delayed-feedback environments (auction holdouts, switchback tests, variance reduction techniques).
• Communication: Ability to explain complex modeling decisions and tradeoffs to Product and business stakeholders; comfortable presenting in cross-functional forums.
• Education: Bachelor's in a quantitative field (CS, Statistics, Math, Engineering, Economics, or similar); Master's/PhD preferred.

Preferred / Nice to Have

• Direct experience with SSP, DSP, or exchange-side yield optimization — particularly floor price optimization, bid landscape modeling, or deal matching algorithms.
• Familiarity with auction theory (first-price vs. second-price dynamics, optimal reserve pricing, revenue equivalence) and its practical implications for programmatic ML.
• Experience with contextual bandits, multi-armed bandits, or reinforcement learning applied to real-time decisioning problems.
• Knowledge of online learning and adaptive algorithms in production environments with non-stationary data distributions.
• Familiarity with privacy-preserving ML techniques relevant to programmatic (differential privacy, federated learning, cookieless attribution modeling).
• Experience with GCP tools (BigQuery, Vertex AI, Dataflow, Pub/Sub) and/or Databricks/Spark for large-scale event processing and model training.
• Exposure to supply forecasting, inventory management, or capacity planning in programmatic or marketplace contexts.
• Familiarity with Impact's affiliate and partnership ecosystem, or prior experience at the intersection of performance marketing and programmatic delivery.

What Sets You Apart

• Marketplace intuition. You understand programmatic auctions not just as an engineer but as an economist — you think about incentive structures, equilibrium dynamics, and how model decisions ripple through the supply-demand stack.
• Full-stack ML ownership. You're as comfortable designing a feature store schema as you are tuning a gradient boosting model or debugging a latency spike in production. You own the whole chain.
• Feedback loop thinking. You don't just deploy models — you design the systems that make them smarter over time. You think about how today's decisions become tomorrow's training signal.
• Rigor under real-world constraints. You know how to run clean experiments in environments where feedback is delayed, data is noisy, and business pressures create tradeoffs. You don't let imperfect conditions become an excuse for imprecise thinking.
• Pragmatic delivery. You ship. You balance the perfect with the production-ready, iterate fast, and know when an MVP outperforms a six-month research project.
• Collaborative depth. You build genuine technical trust with engineering and product partners — not just by having good ideas, but by following through, communicating clearly, and making the integration easy.

Salary Range: $165,000 - $185,000 per year, plus an additional 5% variable annual bonus contingent on Company performance and eligible to receive a Restricted Stock Unit (RSU) grant.

*This is the pay range the Company believes is equitable for this position at the time of this posting. Consistent with applicable law, compensation will be determined based on the skills, qualifications, and experience of the applicant along with the requirements of the position, and the Company reserves the right to modify this pay range at any time.

Benefits and Perks: 

At impact.com, we believe that when you’re happy and fulfilled, you do your best work. That’s why we’ve built a benefits package that supports your well-being, growth, and work-life balance.

• Medical, Dental, and Vision insurance
• Office-only catered lunch every Thursday, a healthy snack bar, and great coffee to keep you fueled 
• Flexible spending accounts and 401(k)
• Flexible Working: Our Responsible PTO policy means you can take the time off you need to rest and recharge. We're committed to a positive work-life balance and provide a flexible environment that allows you to be happy and fulfilled in both your career and your personal life.
• Health and Wellness: Your well-being is a priority. Our mental health and wellness benefit includes up to 12 fully covered therapy/coaching sessions per year, with additional dependent coverage. We also offer a monthly gym reimbursement policy to support your physical health.
• A Stake in Our Growth: We offer Restricted Stock Units (RSUs) as part of our total compensation, giving you a stake in the company's growth with a 3-year vesting schedule, pending Board approval.
• Investing in Your Growth: We’re committed to your continuous learning. Take advantage of our free Coursera subscription and our PXA courses.
• Parental Support: We offer a generous parental leave policy, 26 weeks of fully paid leave for the primary caregiver and 13 weeks fully paid leave for the secondary caregiver.
• Technology Financial Support: We provide a technology stipend to help you set up your home office and a monthly allowance to cover your internet expenses. 

impact.com is proud to be an equal-opportunity workplace. All employees and applicants for employment shall be given fair treatment and equal employment opportunity regardless of their race, ethnicity or ancestry, color or caste, religion or belief, age, sex (including gender identity, gender reassignment, sexual orientation, pregnancy/maternity), national origin, weight, neurodivergence, disability, marital and civil partnership status, caregiving status, veteran status, genetic information, political affiliation, or other prohibited non-merit factors.

#LI_Columbus_OH

About impact.com
impact.com is the world’s leading commerce partnership marketing platform, transforming the way businesses grow by enabling them to discover, manage, and scale partnerships across the entire customer journey. From affiliates and influencers to content publishers, brand ambassadors, and customer advocates, impact.com empowers brands to drive trusted, performance-based growth through authentic relationships. Its award-winning products - Performance (affiliate), Creator (influencer), and Advocate (customer referral) - unify every type of partner into one integrated platform. As consumers increasingly rely on recommendations from people and communities they trust, impact.com helps brands show up where it matters most. Today, over 5,000 global brands - including Walmart, Uber, Shopify, Lenovo, L’Oréal, and Fanatics - rely on impact.com to power more than 350,000 partnerships that deliver measurable business results.

Your Role at impact.com:

We're seeking a Senior Data Scientist to serve as an embedded Data Scientist within our Programmatic Experience Group. You'll own the design and deployment of machine learning models that optimize yield, pricing, and inventory allocation at scale — sitting at the intersection of data science, platform engineering, and marketplace economics.

This is a high-craft, high-ownership individual contributor role. You'll work end-to-end: architecting the data pipelines that feed your models, engineering the features that drive performance, and deploying real-time inference systems that make decisions at speed. Your work directly determines how effectively Impact's programmatic marketplace balances advertiser performance with publisher monetization — making this one of the highest-leverage technical roles in the business.

You'll collaborate closely with Product, Data Science, and Programmatic Delivery Engine Engineering, but you operate with significant autonomy. You're expected to bring both the modeling rigor of a data scientist and the production instincts of an ML engineer — and to be genuinely excited about both.

What You'll Do:

Yield Optimization & Pricing Models

• Design and deploy ML models that optimize auction pricing, bid shading, floor price setting, and yield across Impact's programmatic inventory.
• Build and iterate on real-time pricing algorithms that balance short-term revenue efficiency with long-term publisher and advertiser health.
• Develop and maintain feedback loops that allow pricing models to adapt to shifting market conditions, inventory mix, and demand patterns.
• Quantify the revenue impact of pricing model improvements; communicate tradeoffs between yield maximization, fill rate, and partner ROI to stakeholders.

Inventory Allocation & Supply Optimization

• Own ML-driven inventory allocation logic: routing, pacing, and matching supply to demand across partner segments, deal types, and campaign objectives.
• Build models that forecast inventory availability, demand curves, and clearing prices to support proactive allocation decisions.
• Identify and address inefficiencies in inventory utilization — including unsold inventory, suboptimal deal matching, and allocation imbalances across the publisher base.

Data Architecture & Feature Engineering

• Design and own the data infrastructure that feeds programmatic models: event pipelines, feature stores, training datasets, and real-time feature serving.
• Engineer high-signal features from auction logs, bid stream data, user signals, contextual attributes, and historical performance — at the scale of programmatic data volumes.
• Build robust data pipelines with production-grade standards: reliability, observability, versioning, and efficient reprocessing.

Real-Time Inference & Production ML

• Deploy models to production real-time inference environments; own latency, reliability, and throughput requirements for auction-time decision-making.
• Build monitoring systems that track model performance, data drift, and system health in production; define alerting thresholds and retraining triggers.
• Partner with MLOps and Platform Engineering to ensure scalable, low-latency serving infrastructure meets SLOs under high-volume auction traffic.
• Own the full model lifecycle: training, evaluation, deployment, A/B testing, and iteration.

Experimentation & Performance Measurement

• Design and execute rigorous A/B and holdout experiments to measure the causal impact of model changes on yield, fill rate, advertiser performance, and publisher revenue.
• Build evaluation frameworks that go beyond offline metrics — validating model behavior in live auction environments where feedback signals are delayed or noisy.
• Translate experimental results into clear business narratives; present findings and recommendations to Product and business stakeholders.

Self-Learning Systems & Feedback Loops

• Research and implement adaptive, self-learning components within the programmatic stack — including contextual bandits, reinforcement learning signals, and online learning approaches where appropriate.
• Design feedback mechanisms that close the loop between auction outcomes, model updates, and system behavior; reduce reliance on manual tuning and rule-based overrides.
• Stay current with advances in programmatic ML, auction theory, and online optimization; evaluate applicability to Impact's specific marketplace dynamics.

Cross-Functional Collaboration

• Serve as the primary ML technical partner for the Rubicon product and engineering teams; translate business requirements into modeling approaches and communicate technical tradeoffs clearly.
• Collaborate with Data Science peers on shared infrastructure, modeling standards, and cross-domain feature reuse.
• Document models, architectures, and experimental findings to a standard that enables review, replication, and knowledge transfer across teams.

What You Bring:

Required

• Experience: 5+ years in data science, ML engineering, or quantitative research, with at least 2+ years building and deploying ML models in programmatic advertising, ad tech, marketplace optimization, or a closely related domain (e.g., real-time bidding, dynamic pricing, auction systems).
• Programmatic & marketplace depth: Demonstrated understanding of programmatic auction mechanics (RTB, header bidding, floor pricing, deal types, bid shading) and how ML can be applied to optimize outcomes across the supply-demand stack.
• Production ML engineering: Proven ability to take models from prototype to production independently — including real-time inference, monitoring, retraining pipelines, and SLO ownership.
• Data architecture: Experience designing and building data pipelines, feature stores, and training infrastructure for high-volume, low-latency ML systems.
• Technical skills:
• Strong Python and SQL; proficiency with ML libraries (scikit-learn, XGBoost, LightGBM, PyTorch/TensorFlow) and large-scale data tools (Spark, Kafka, or equivalent streaming/batch frameworks).
• Experience with real-time feature serving and low-latency model deployment (REST APIs, gRPC, or streaming inference).
• Familiarity with production ML workflows: model versioning, drift monitoring, A/B testing, evaluation, and retraining.
• Experience processing and modeling at programmatic data scale: high-cardinality auction logs, bid stream data, impression and click events.
• Experimentation rigor: Strong grasp of causal inference and experiment design in online, delayed-feedback environments (auction holdouts, switchback tests, variance reduction techniques).
• Communication: Ability to explain complex modeling decisions and tradeoffs to Product and business stakeholders; comfortable presenting in cross-functional forums.
• Education: Bachelor's in a quantitative field (CS, Statistics, Math, Engineering, Economics, or similar); Master's/PhD preferred.

Preferred / Nice to Have

• Direct experience with SSP, DSP, or exchange-side yield optimization — particularly floor price optimization, bid landscape modeling, or deal matching algorithms.
• Familiarity with auction theory (first-price vs. second-price dynamics, optimal reserve pricing, revenue equivalence) and its practical implications for programmatic ML.
• Experience with contextual bandits, multi-armed bandits, or reinforcement learning applied to real-time decisioning problems.
• Knowledge of online learning and adaptive algorithms in production environments with non-stationary data distributions.
• Familiarity with privacy-preserving ML techniques relevant to programmatic (differential privacy, federated learning, cookieless attribution modeling).
• Experience with GCP tools (BigQuery, Vertex AI, Dataflow, Pub/Sub) and/or Databricks/Spark for large-scale event processing and model training.
• Exposure to supply forecasting, inventory management, or capacity planning in programmatic or marketplace contexts.
• Familiarity with Impact's affiliate and partnership ecosystem, or prior experience at the intersection of performance marketing and programmatic delivery.

What Sets You Apart

• Marketplace intuition. You understand programmatic auctions not just as an engineer but as an economist — you think about incentive structures, equilibrium dynamics, and how model decisions ripple through the supply-demand stack.
• Full-stack ML ownership. You're as comfortable designing a feature store schema as you are tuning a gradient boosting model or debugging a latency spike in production. You own the whole chain.
• Feedback loop thinking. You don't just deploy models — you design the systems that make them smarter over time. You think about how today's decisions become tomorrow's training signal.
• Rigor under real-world constraints. You know how to run clean experiments in environments where feedback is delayed, data is noisy, and business pressures create tradeoffs. You don't let imperfect conditions become an excuse for imprecise thinking.
• Pragmatic delivery. You ship. You balance the perfect with the production-ready, iterate fast, and know when an MVP outperforms a six-month research project.
• Collaborative depth. You build genuine technical trust with engineering and product partners — not just by having good ideas, but by following through, communicating clearly, and making the integration easy.

Salary Range: $165,000 - $185,000 per year, plus an additional 5% variable annual bonus contingent on Company performance and eligible to receive a Restricted Stock Unit (RSU) grant.

*This is the pay range the Company believes is equitable for this position at the time of this posting. Consistent with applicable law, compensation will be determined based on the skills, qualifications, and experience of the applicant along with the requirements of the position, and the Company reserves the right to modify this pay range at any time.

Benefits and Perks: 

At impact.com, we believe that when you’re happy and fulfilled, you do your best work. That’s why we’ve built a benefits package that supports your well-being, growth, and work-life balance.

• Medical, Dental, and Vision insurance
• Office-only catered lunch every Thursday, a healthy snack bar, and great coffee to keep you fueled 
• Flexible spending accounts and 401(k)
• Flexible Working: Our Responsible PTO policy means you can take the time off you need to rest and recharge. We're committed to a positive work-life balance and provide a flexible environment that allows you to be happy and fulfilled in both your career and your personal life.
• Health and Wellness: Your well-being is a priority. Our mental health and wellness benefit includes up to 12 fully covered therapy/coaching sessions per year, with additional dependent coverage. We also offer a monthly gym reimbursement policy to support your physical health.
• A Stake in Our Growth: We offer Restricted Stock Units (RSUs) as part of our total compensation, giving you a stake in the company's growth with a 3-year vesting schedule, pending Board approval.
• Investing in Your Growth: We’re committed to your continuous learning. Take advantage of our free Coursera subscription and our PXA courses.
• Parental Support: We offer a generous parental leave policy, 26 weeks of fully paid leave for the primary caregiver and 13 weeks fully paid leave for the secondary caregiver.
• Technology Financial Support: We provide a technology stipend to help you set up your home office and a monthly allowance to cover your internet expenses. 

impact.com is proud to be an equal-opportunity workplace. All employees and applicants for employment shall be given fair treatment and equal employment opportunity regardless of their race, ethnicity or ancestry, color or caste, religion or belief, age, sex (including gender identity, gender reassignment, sexual orientation, pregnancy/maternity), national origin, weight, neurodivergence, disability, marital and civil partnership status, caregiving status, veteran status, genetic information, political affiliation, or other prohibited non-merit factors.

#LI_Seattle

About impact.com
impact.com is the world’s leading commerce partnership marketing platform, transforming the way businesses grow by enabling them to discover, manage, and scale partnerships across the entire customer journey. From affiliates and influencers to content publishers, brand ambassadors, and customer advocates, impact.com empowers brands to drive trusted, performance-based growth through authentic relationships. Its award-winning products - Performance (affiliate), Creator (influencer), and Advocate (customer referral) - unify every type of partner into one integrated platform. As consumers increasingly rely on recommendations from people and communities they trust, impact.com helps brands show up where it matters most. Today, over 5,000 global brands - including Walmart, Uber, Shopify, Lenovo, L’Oréal, and Fanatics - rely on impact.com to power more than 350,000 partnerships that deliver measurable business results.

Your Role at impact.com:

We're seeking a Senior Data Scientist to serve as an embedded Data Scientist within our Programmatic Experience Group. You'll own the design and deployment of machine learning models that optimize yield, pricing, and inventory allocation at scale — sitting at the intersection of data science, platform engineering, and marketplace economics.

This is a high-craft, high-ownership individual contributor role. You'll work end-to-end: architecting the data pipelines that feed your models, engineering the features that drive performance, and deploying real-time inference systems that make decisions at speed. Your work directly determines how effectively Impact's programmatic marketplace balances advertiser performance with publisher monetization — making this one of the highest-leverage technical roles in the business.

You'll collaborate closely with Product, Data Science, and Programmatic Delivery Engine Engineering, but you operate with significant autonomy. You're expected to bring both the modeling rigor of a data scientist and the production instincts of an ML engineer — and to be genuinely excited about both.

What You'll Do:

Yield Optimization & Pricing Models

• Design and deploy ML models that optimize auction pricing, bid shading, floor price setting, and yield across Impact's programmatic inventory.
• Build and iterate on real-time pricing algorithms that balance short-term revenue efficiency with long-term publisher and advertiser health.
• Develop and maintain feedback loops that allow pricing models to adapt to shifting market conditions, inventory mix, and demand patterns.
• Quantify the revenue impact of pricing model improvements; communicate tradeoffs between yield maximization, fill rate, and partner ROI to stakeholders.

Inventory Allocation & Supply Optimization

• Own ML-driven inventory allocation logic: routing, pacing, and matching supply to demand across partner segments, deal types, and campaign objectives.
• Build models that forecast inventory availability, demand curves, and clearing prices to support proactive allocation decisions.
• Identify and address inefficiencies in inventory utilization — including unsold inventory, suboptimal deal matching, and allocation imbalances across the publisher base.

Data Architecture & Feature Engineering

• Design and own the data infrastructure that feeds programmatic models: event pipelines, feature stores, training datasets, and real-time feature serving.
• Engineer high-signal features from auction logs, bid stream data, user signals, contextual attributes, and historical performance — at the scale of programmatic data volumes.
• Build robust data pipelines with production-grade standards: reliability, observability, versioning, and efficient reprocessing.

Real-Time Inference & Production ML

• Deploy models to production real-time inference environments; own latency, reliability, and throughput requirements for auction-time decision-making.
• Build monitoring systems that track model performance, data drift, and system health in production; define alerting thresholds and retraining triggers.
• Partner with MLOps and Platform Engineering to ensure scalable, low-latency serving infrastructure meets SLOs under high-volume auction traffic.
• Own the full model lifecycle: training, evaluation, deployment, A/B testing, and iteration.

Experimentation & Performance Measurement

• Design and execute rigorous A/B and holdout experiments to measure the causal impact of model changes on yield, fill rate, advertiser performance, and publisher revenue.
• Build evaluation frameworks that go beyond offline metrics — validating model behavior in live auction environments where feedback signals are delayed or noisy.
• Translate experimental results into clear business narratives; present findings and recommendations to Product and business stakeholders.

Self-Learning Systems & Feedback Loops

• Research and implement adaptive, self-learning components within the programmatic stack — including contextual bandits, reinforcement learning signals, and online learning approaches where appropriate.
• Design feedback mechanisms that close the loop between auction outcomes, model updates, and system behavior; reduce reliance on manual tuning and rule-based overrides.
• Stay current with advances in programmatic ML, auction theory, and online optimization; evaluate applicability to Impact's specific marketplace dynamics.

Cross-Functional Collaboration

• Serve as the primary ML technical partner for the Rubicon product and engineering teams; translate business requirements into modeling approaches and communicate technical tradeoffs clearly.
• Collaborate with Data Science peers on shared infrastructure, modeling standards, and cross-domain feature reuse.
• Document models, architectures, and experimental findings to a standard that enables review, replication, and knowledge transfer across teams.

What You Bring:

Required

• Experience: 5+ years in data science, ML engineering, or quantitative research, with at least 2+ years building and deploying ML models in programmatic advertising, ad tech, marketplace optimization, or a closely related domain (e.g., real-time bidding, dynamic pricing, auction systems).
• Programmatic & marketplace depth: Demonstrated understanding of programmatic auction mechanics (RTB, header bidding, floor pricing, deal types, bid shading) and how ML can be applied to optimize outcomes across the supply-demand stack.
• Production ML engineering: Proven ability to take models from prototype to production independently — including real-time inference, monitoring, retraining pipelines, and SLO ownership.
• Data architecture: Experience designing and building data pipelines, feature stores, and training infrastructure for high-volume, low-latency ML systems.
• Technical skills:
• Strong Python and SQL; proficiency with ML libraries (scikit-learn, XGBoost, LightGBM, PyTorch/TensorFlow) and large-scale data tools (Spark, Kafka, or equivalent streaming/batch frameworks).
• Experience with real-time feature serving and low-latency model deployment (REST APIs, gRPC, or streaming inference).
• Familiarity with production ML workflows: model versioning, drift monitoring, A/B testing, evaluation, and retraining.
• Experience processing and modeling at programmatic data scale: high-cardinality auction logs, bid stream data, impression and click events.
• Experimentation rigor: Strong grasp of causal inference and experiment design in online, delayed-feedback environments (auction holdouts, switchback tests, variance reduction techniques).
• Communication: Ability to explain complex modeling decisions and tradeoffs to Product and business stakeholders; comfortable presenting in cross-functional forums.
• Education: Bachelor's in a quantitative field (CS, Statistics, Math, Engineering, Economics, or similar); Master's/PhD preferred.

Preferred / Nice to Have

• Direct experience with SSP, DSP, or exchange-side yield optimization — particularly floor price optimization, bid landscape modeling, or deal matching algorithms.
• Familiarity with auction theory (first-price vs. second-price dynamics, optimal reserve pricing, revenue equivalence) and its practical implications for programmatic ML.
• Experience with contextual bandits, multi-armed bandits, or reinforcement learning applied to real-time decisioning problems.
• Knowledge of online learning and adaptive algorithms in production environments with non-stationary data distributions.
• Familiarity with privacy-preserving ML techniques relevant to programmatic (differential privacy, federated learning, cookieless attribution modeling).
• Experience with GCP tools (BigQuery, Vertex AI, Dataflow, Pub/Sub) and/or Databricks/Spark for large-scale event processing and model training.
• Exposure to supply forecasting, inventory management, or capacity planning in programmatic or marketplace contexts.
• Familiarity with Impact's affiliate and partnership ecosystem, or prior experience at the intersection of performance marketing and programmatic delivery.

What Sets You Apart

• Marketplace intuition. You understand programmatic auctions not just as an engineer but as an economist — you think about incentive structures, equilibrium dynamics, and how model decisions ripple through the supply-demand stack.
• Full-stack ML ownership. You're as comfortable designing a feature store schema as you are tuning a gradient boosting model or debugging a latency spike in production. You own the whole chain.
• Feedback loop thinking. You don't just deploy models — you design the systems that make them smarter over time. You think about how today's decisions become tomorrow's training signal.
• Rigor under real-world constraints. You know how to run clean experiments in environments where feedback is delayed, data is noisy, and business pressures create tradeoffs. You don't let imperfect conditions become an excuse for imprecise thinking.
• Pragmatic delivery. You ship. You balance the perfect with the production-ready, iterate fast, and know when an MVP outperforms a six-month research project.
• Collaborative depth. You build genuine technical trust with engineering and product partners — not just by having good ideas, but by following through, communicating clearly, and making the integration easy.

Salary Range: $165,000 - $185,000 per year, plus an additional 5% variable annual bonus contingent on Company performance and eligible to receive a Restricted Stock Unit (RSU) grant.

*This is the pay range the Company believes is equitable for this position at the time of this posting. Consistent with applicable law, compensation will be determined based on the skills, qualifications, and experience of the applicant along with the requirements of the position, and the Company reserves the right to modify this pay range at any time.

Benefits and Perks: 

At impact.com, we believe that when you’re happy and fulfilled, you do your best work. That’s why we’ve built a benefits package that supports your well-being, growth, and work-life balance.

• Strong extended health benefits: Health & Prescription coverage, vision and dental care, virtual health care, out-of-country medical coverage
• Insurance coverage (life, short-term disability, long-term disability, and more)
• Health Care Spending Account
• Two different Employee Assistance Programs
• Flexible Working: Our Responsible PTO policy means you can take the time off you need to rest and recharge. We're committed to a positive work-life balance and provide a flexible environment that allows you to be happy and fulfilled in both your career and your personal life.
• Health and Wellness: Your well-being is a priority. Our mental health and wellness benefit includes up to 12 fully covered therapy/coaching sessions per year, with additional dependent coverage. We also offer a monthly gym reimbursement policy to support your physical health.
• A Stake in Our Growth: We offer Restricted Stock Units (RSUs) as part of our total compensation, giving you a stake in the company's growth with a 3-year vesting schedule, pending Board approval.
• Investing in Your Growth: We’re committed to your continuous learning. Take advantage of our free Coursera subscription and our PXA courses.
• Parental Support: We offer a generous parental leave policy, 26 weeks of fully paid leave for the primary caregiver and 13 weeks fully paid leave for the secondary caregiver.
• Technology Financial Support: We provide a technology stipend to help you set up your home office and a monthly allowance to cover your internet expenses. 

Note: Benefits may vary by location and are subject to local regulations.

impact.com is proud to be an equal-opportunity workplace. All employees and applicants for employment shall be given fair treatment and equal employment opportunity regardless of their race, ethnicity or ancestry, color or caste, religion or belief, age, sex (including gender identity, gender reassignment, sexual orientation, pregnancy/maternity), national origin, weight, neurodivergence, disability, marital and civil partnership status, caregiving status, veteran status, genetic information, political affiliation, or other prohibited non-merit factors.

#LI_Vancouver_Canada

About impact.com
impact.com is the world’s leading commerce partnership marketing platform, transforming the way businesses grow by enabling them to discover, manage, and scale partnerships across the entire customer journey. From affiliates and influencers to content publishers, brand ambassadors, and customer advocates, impact.com empowers brands to drive trusted, performance-based growth through authentic relationships. Its award-winning products - Performance (affiliate), Creator (influencer), and Advocate (customer referral) - unify every type of partner into one integrated platform. As consumers increasingly rely on recommendations from people and communities they trust, impact.com helps brands show up where it matters most. Today, over 5,000 global brands - including Walmart, Uber, Shopify, Lenovo, L’Oréal, and Fanatics - rely on impact.com to power more than 350,000 partnerships that deliver measurable business results.

Your Role at impact.com:

We're seeking a Senior Data Scientist to serve as an embedded Data Scientist within our Programmatic Experience Group. You'll own the design and deployment of machine learning models that optimize yield, pricing, and inventory allocation at scale — sitting at the intersection of data science, platform engineering, and marketplace economics.

This is a high-craft, high-ownership individual contributor role. You'll work end-to-end: architecting the data pipelines that feed your models, engineering the features that drive performance, and deploying real-time inference systems that make decisions at speed. Your work directly determines how effectively Impact's programmatic marketplace balances advertiser performance with publisher monetization — making this one of the highest-leverage technical roles in the business.

You'll collaborate closely with Product, Data Science, and Programmatic Delivery Engine Engineering, but you operate with significant autonomy. You're expected to bring both the modeling rigor of a data scientist and the production instincts of an ML engineer — and to be genuinely excited about both.

What You'll Do:

Yield Optimization & Pricing Models

• Design and deploy ML models that optimize auction pricing, bid shading, floor price setting, and yield across Impact's programmatic inventory.
• Build and iterate on real-time pricing algorithms that balance short-term revenue efficiency with long-term publisher and advertiser health.
• Develop and maintain feedback loops that allow pricing models to adapt to shifting market conditions, inventory mix, and demand patterns.
• Quantify the revenue impact of pricing model improvements; communicate tradeoffs between yield maximization, fill rate, and partner ROI to stakeholders.

Inventory Allocation & Supply Optimization

• Own ML-driven inventory allocation logic: routing, pacing, and matching supply to demand across partner segments, deal types, and campaign objectives.
• Build models that forecast inventory availability, demand curves, and clearing prices to support proactive allocation decisions.
• Identify and address inefficiencies in inventory utilization — including unsold inventory, suboptimal deal matching, and allocation imbalances across the publisher base.

Data Architecture & Feature Engineering

• Design and own the data infrastructure that feeds programmatic models: event pipelines, feature stores, training datasets, and real-time feature serving.
• Engineer high-signal features from auction logs, bid stream data, user signals, contextual attributes, and historical performance — at the scale of programmatic data volumes.
• Build robust data pipelines with production-grade standards: reliability, observability, versioning, and efficient reprocessing.

Real-Time Inference & Production ML

• Deploy models to production real-time inference environments; own latency, reliability, and throughput requirements for auction-time decision-making.
• Build monitoring systems that track model performance, data drift, and system health in production; define alerting thresholds and retraining triggers.
• Partner with MLOps and Platform Engineering to ensure scalable, low-latency serving infrastructure meets SLOs under high-volume auction traffic.
• Own the full model lifecycle: training, evaluation, deployment, A/B testing, and iteration.

Experimentation & Performance Measurement

• Design and execute rigorous A/B and holdout experiments to measure the causal impact of model changes on yield, fill rate, advertiser performance, and publisher revenue.
• Build evaluation frameworks that go beyond offline metrics — validating model behavior in live auction environments where feedback signals are delayed or noisy.
• Translate experimental results into clear business narratives; present findings and recommendations to Product and business stakeholders.

Self-Learning Systems & Feedback Loops

• Research and implement adaptive, self-learning components within the programmatic stack — including contextual bandits, reinforcement learning signals, and online learning approaches where appropriate.
• Design feedback mechanisms that close the loop between auction outcomes, model updates, and system behavior; reduce reliance on manual tuning and rule-based overrides.
• Stay current with advances in programmatic ML, auction theory, and online optimization; evaluate applicability to Impact's specific marketplace dynamics.

Cross-Functional Collaboration

• Serve as the primary ML technical partner for the Rubicon product and engineering teams; translate business requirements into modeling approaches and communicate technical tradeoffs clearly.
• Collaborate with Data Science peers on shared infrastructure, modeling standards, and cross-domain feature reuse.
• Document models, architectures, and experimental findings to a standard that enables review, replication, and knowledge transfer across teams.

What You Bring:

Required

• Experience: 5+ years in data science, ML engineering, or quantitative research, with at least 2+ years building and deploying ML models in programmatic advertising, ad tech, marketplace optimization, or a closely related domain (e.g., real-time bidding, dynamic pricing, auction systems).
• Programmatic & marketplace depth: Demonstrated understanding of programmatic auction mechanics (RTB, header bidding, floor pricing, deal types, bid shading) and how ML can be applied to optimize outcomes across the supply-demand stack.
• Production ML engineering: Proven ability to take models from prototype to production independently — including real-time inference, monitoring, retraining pipelines, and SLO ownership.
• Data architecture: Experience designing and building data pipelines, feature stores, and training infrastructure for high-volume, low-latency ML systems.
• Technical skills:
• Strong Python and SQL; proficiency with ML libraries (scikit-learn, XGBoost, LightGBM, PyTorch/TensorFlow) and large-scale data tools (Spark, Kafka, or equivalent streaming/batch frameworks).
• Experience with real-time feature serving and low-latency model deployment (REST APIs, gRPC, or streaming inference).
• Familiarity with production ML workflows: model versioning, drift monitoring, A/B testing, evaluation, and retraining.
• Experience processing and modeling at programmatic data scale: high-cardinality auction logs, bid stream data, impression and click events.
• Experimentation rigor: Strong grasp of causal inference and experiment design in online, delayed-feedback environments (auction holdouts, switchback tests, variance reduction techniques).
• Communication: Ability to explain complex modeling decisions and tradeoffs to Product and business stakeholders; comfortable presenting in cross-functional forums.
• Education: Bachelor's in a quantitative field (CS, Statistics, Math, Engineering, Economics, or similar); Master's/PhD preferred.

Preferred / Nice to Have

• Direct experience with SSP, DSP, or exchange-side yield optimization — particularly floor price optimization, bid landscape modeling, or deal matching algorithms.
• Familiarity with auction theory (first-price vs. second-price dynamics, optimal reserve pricing, revenue equivalence) and its practical implications for programmatic ML.
• Experience with contextual bandits, multi-armed bandits, or reinforcement learning applied to real-time decisioning problems.
• Knowledge of online learning and adaptive algorithms in production environments with non-stationary data distributions.
• Familiarity with privacy-preserving ML techniques relevant to programmatic (differential privacy, federated learning, cookieless attribution modeling).
• Experience with GCP tools (BigQuery, Vertex AI, Dataflow, Pub/Sub) and/or Databricks/Spark for large-scale event processing and model training.
• Exposure to supply forecasting, inventory management, or capacity planning in programmatic or marketplace contexts.
• Familiarity with Impact's affiliate and partnership ecosystem, or prior experience at the intersection of performance marketing and programmatic delivery.

What Sets You Apart

• Marketplace intuition. You understand programmatic auctions not just as an engineer but as an economist — you think about incentive structures, equilibrium dynamics, and how model decisions ripple through the supply-demand stack.
• Full-stack ML ownership. You're as comfortable designing a feature store schema as you are tuning a gradient boosting model or debugging a latency spike in production. You own the whole chain.
• Feedback loop thinking. You don't just deploy models — you design the systems that make them smarter over time. You think about how today's decisions become tomorrow's training signal.
• Rigor under real-world constraints. You know how to run clean experiments in environments where feedback is delayed, data is noisy, and business pressures create tradeoffs. You don't let imperfect conditions become an excuse for imprecise thinking.
• Pragmatic delivery. You ship. You balance the perfect with the production-ready, iterate fast, and know when an MVP outperforms a six-month research project.
• Collaborative depth. You build genuine technical trust with engineering and product partners — not just by having good ideas, but by following through, communicating clearly, and making the integration easy.

Salary Range: $165,000 - $185,000 per year, plus an additional 5% variable annual bonus contingent on Company performance and eligible to receive a Restricted Stock Unit (RSU) grant.

*This is the pay range the Company believes is equitable for this position at the time of this posting. Consistent with applicable law, compensation will be determined based on the skills, qualifications, and experience of the applicant along with the requirements of the position, and the Company reserves the right to modify this pay range at any time.

Benefits and Perks: 

At impact.com, we believe that when you’re happy and fulfilled, you do your best work. That’s why we’ve built a benefits package that supports your well-being, growth, and work-life balance.

• Medical, Dental, and Vision insurance
• Office-only catered lunch every Thursday, a healthy snack bar, and great coffee to keep you fueled 
• Flexible spending accounts and 401(k)
• Flexible Working: Our Responsible PTO policy means you can take the time off you need to rest and recharge. We're committed to a positive work-life balance and provide a flexible environment that allows you to be happy and fulfilled in both your career and your personal life.
• Health and Wellness: Your well-being is a priority. Our mental health and wellness benefit includes up to 12 fully covered therapy/coaching sessions per year, with additional dependent coverage. We also offer a monthly gym reimbursement policy to support your physical health.
• A Stake in Our Growth: We offer Restricted Stock Units (RSUs) as part of our total compensation, giving you a stake in the company's growth with a 3-year vesting schedule, pending Board approval.
• Investing in Your Growth: We’re committed to your continuous learning. Take advantage of our free Coursera subscription and our PXA courses.
• Parental Support: We offer a generous parental leave policy, 26 weeks of fully paid leave for the primary caregiver and 13 weeks fully paid leave for the secondary caregiver.
• Technology Financial Support: We provide a technology stipend to help you set up your home office and a monthly allowance to cover your internet expenses. 

impact.com is proud to be an equal-opportunity workplace. All employees and applicants for employment shall be given fair treatment and equal employment opportunity regardless of their race, ethnicity or ancestry, color or caste, religion or belief, age, sex (including gender identity, gender reassignment, sexual orientation, pregnancy/maternity), national origin, weight, neurodivergence, disability, marital and civil partnership status, caregiving status, veteran status, genetic information, political affiliation, or other prohibited non-merit factors.

#LI_NewYork_NewYork

Forge Your Future with Us:

At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you’re driven by purpose and excited to make a tangible impact, this is where your journey begins.

Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won’t just watch innovation happen — you’ll be part of it. Whether you’re scaling AAV manufacturing, collaborating on cutting-edge therapies, or supporting complex technical projects, you’ll play a key role in bringing hope to patients with genetic diseases.

What sets Forge apart is our culture of H.O.P.E. We are hardworking, showing up each day with determination and grit. We are open, creating a space where ideas flow freely, and every voice is valued. We are purpose-driven, with every task directly tied to changing lives. And we are engaged, energized by the challenges we face and the milestones we achieve together.

At Forge, your growth matters. We’re committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement. Our people are our greatest investment, and we’re proud to see team members grow with us.

If you’re ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself.

About The Role:   

The Scientist II provides active leadership and execution of the laboratory experiments and protocols for upstream process development efforts. This individual will lead projects and complex experiments, train junior scientists, and actively contribute to the advancement of AAV manufacturing processes. 

Responsibilities: 

• Senior-level technical contributor and subject matter expert for upstream systems and process strategy 

• Independently manages multiple projects or client programs simultaneously, maintaining a high degree of quality, scientific rigor, and compliance 

• Leads process development activities for early- to late-stage programs, including scale-up, technology transfer, and validation support 

• Designs and executes complex DoE studies, authors technical reports, and contributes to regulatory documentation 

• Anticipates challenges in upstream scale-up and proactively develops solutions to ensure technical success 

• Acts as a key liaison between Process Development, Manufacturing, and Quality teams to align on strategy and ensure smooth GMP execution 

• Contributes scientific rationale for tech transfer packages and GMP documentation without owning official SOPs or batch records 

• Mentors junior scientists and associates through day-to-day technical guidance, fostering development in experimental design, documentation standards, and scientific reasoning 

Qualifications: 

• Bachelor’s Degree in Chemical Engineering, Bioengineering, Biology, or related discipline (or equivalent experience) 

• Working knowledge of cell culture techniques utilizing mammalian cells 

• Proven ability to operate and troubleshoot bioreactors 

• Experience planning, conducting and reviewing experimental data with minimal oversight 

• Experience training and development of other team members 

• Experience analyzing data sets and utilizing the corresponding data to influence decision making 

• Experience working with external collaborators (clients, external technology transfers, etc.) 

• Project management experience 

Preferred Skills: 

• Master’s Degree or PhD in Chemical Engineering, Bioengineering, Biology, or related discipline (or equivalent experience) 

• Experience working with viral vectors (AAV, Lentivirus, etc.) 

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned.  

Work Environment and Physical Demands   

This position works in both a laboratory environment and typical office environment where the physical work demands will vary depending on the specific tasks and duties required of the job. The employee will be stationary (standing/sitting) for extended periods of time. Employees regularly wear personal protective equipment based on the task being performed. Must be able to work in a confined space, such as a clean room or laboratory environment. Ability to identify small details within the field of vision, distinguish between different colors, and accurately identify objects within a specific area. 

Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.  

We’ve Got You Covered:  

At Forge Biologics, we believe our people deserve to be taken care of – in and out of the workplace. We’ve built a comprehensive compensation and benefits package designed to help you thrive, grow, and feel valued every step of the way:  

Health from day one 

• Health, dental and vision insurance start your first day – with 90% of premiums covered for you and your family.  

Time to recharge 

• A competitive paid time off plan – because rest fuels innovation.  

• 12 weeks of fully paid parental leave so you can focus on family when it matters most.  

Rewarding your impact 

• Annual bonus opportunities for all full-time team members.  

• 401(k) with company match to help you plan for the future.  

• Special employee discounts, including childcare and dependent care savings.  

Your wellness, supported 

• Onsite fitness facility at The Hearth. 

• Mental health counseling and financial planning services through our Employee Assistance Program.  

• Employer-paid short and long-term disability coverage to protect your peace of mind.  

Fuel for your workday 

• A fully stocked kitchen with free snacks and beverages – we keep you energized and ready for what’s next.  

Grow with us 

• Ongoing professional development resources, training, and mentorship programs to help you build your care and grow within Forge.  

Forge Your Future with Us: 

At Forge Biologics, we believe in turning bold ideas into life-changing realities. Our mission is simple yet powerful: to enable access to life-changing gene therapies and help bring them from ideas into reality. We partner with scientists, physicians, biotech and pharma innovators, and patient communities — all united by one goal: improving lives. If you’re driven by purpose and excited to make a tangible impact, this is where your journey begins. 

Our team works out of The Hearth, a state-of-the-art, 200,000-square-foot cGMP facility in Columbus, Ohio. Here, you won’t just watch innovation happen — you’ll be part of it. Whether you’re scaling AAV manufacturing, collaborating on cutting-edge therapies, or supporting complex technical projects, you’ll play a key role in bringing hope to patients with genetic diseases. 

What sets Forge apart is our culture of H.O.P.E. We are hardworking, showing up each day with determination and grit. We are open, creating a space where ideas flow freely and every voice is valued. We are purpose-driven, with every task directly tied to changing lives. And we are engaged, energized by the challenges we face and the milestones we achieve together. 

At Forge, your growth matters. We’re committed to helping you expand your skills, take on new challenges, and develop your career through mentorship, hands-on learning, and opportunities for advancement. Our people are our greatest investment, and we’re proud to see team members grow with us. 

If you’re ready to use your talent to help deliver hope to patients around the world, join us — and be part of something bigger than yourself. 

About The Role:   

As an Associate Scientist II, you will play a key role in developing, optimizing, and supporting gene therapy manufacturing processes within the Manufacturing Science and Technology (MS&T) department. This multidisciplinary position partners closely with process development, manufacturing, quality, validation, facilities and engineering, and regulatory teams to ensure upstream, downstream, fill‑finish, buffer preparation, and support‑function processes are scalable, robust, and aligned with regulatory expectations. In this role, you will execute moderately complex, recurring assignments using established procedures, applying sound judgment to resolve straightforward issues and escalating exceptions when needed. You will help identify minor process gaps, contribute to continuous improvement efforts, and strengthen overall operational reliability. Through this work, you will support day‑to‑day operational excellence, enhance cross‑functional readiness, and contribute meaningfully to the organization’s broader success. 

Responsibilities: 

• Execute technology transfer activities from Process Development or clients into GMP Manufacturing, including defining critical quality attributes, key process parameters, and conditions essential for compliant manufacturing under cGMPs. 

• Serve as a technical contributor during technology transfer by reviewing client and Process Development processes and generating required transfer documentation. 

• Support the development, review, and maintenance of key documentation such as manufacturing batch records, production plans, bills of materials and SOPs. 

• Perform process monitoring by collecting, analyzing, and summarizing manufacturing data; prepare and present campaign summaries and related reports. 

• Support GMP execution of new processes and act as a Subject Matter Expert (SME) for change controls, deviation investigations, and CAPAs. 

• Track progress of routine manufacturing and technology transfer activities, provide timely updates, and proactively identify operational risks and mitigation strategies. 

• Build strong working relationships with internal teams and external clients, communicating responsibilities, expectations, and technical information clearly and respectfully to ensure GMP readiness and provide technical support throughout production campaigns. 

• Identify opportunities for process optimization and efficiency improvements across platform manufacturing processes and contribute to discussions on continuous improvement. 

Qualifications: 

• Bachelor’s degree in a relevant scientific discipline with 2+ years of directly related industry experience 

• Behaves ethically and in alignment with organizational values, showing strong communication, organizational, interpersonal, and emerging problem‑solving skills 

• Demonstrates sound judgment when working within clearly defined boundaries and seeks guidance appropriately 

• Collaborates effectively by assisting teammates, completing assigned tasks, and contributing constructively to group discussions 

Preferred Skills: 

• Experience working with viral vectors (AAV, Lentivirus, etc.). 

• Proven track record in supporting tech transfers. 

This job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee. Duties, responsibilities and activities may change or new ones may be assigned.  

Work Environment and Physical Demands   

The work environment is fast paced.  This position has the utmost responsibility for comprehending biologics manufacturing compliance with procedures and regulations regarding a safe and collaborative work environment relative to actions and conduct.  

This position works in a typical office environment where the physical demand varies depending on the specific tasks and duties assigned. The employee may be stationary (standing/sitting) for extended periods of time. The employee will be made aware and acknowledge established procedures regarding personal protective equipment and safety requirements specific to the company. Must be able to work in office space and trained & qualified to enter a production suite(s) or laboratory environment for general understanding of the business. 

Forge Biologics is an equal opportunity employer dedicated to building an inclusive and diverse workforce. Forge Biologics, provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.  

We’ve Got You Covered:  

At Forge Biologics, we believe our people deserve to be taken care of – in and out of the workplace. We’ve built a comprehensive compensation and benefits package designed to help you thrive, grow, and feel valued every step of the way:  

Health from day one 

• Health, dental and vision insurance start your first day – with 90% of premiums covered for you and your family.  

Time to recharge 

• A competitive paid time off plan – because rest fuels innovation.  

• 12 weeks of fully paid parental leave so you can focus on family when it matters most.  

Rewarding your impact 

• Annual bonus opportunities for all full-time team members.  

• 401(k) with company match to help you plan for the future.  

• Special employee discounts, including childcare and dependent care savings.  

Your wellness, supported 

• Onsite fitness facility at The Hearth. 

• Mental health counseling and financial planning services through our Employee Assistance Program.  

• Employer-paid short and long-term disability coverage to protect your peace of mind.  

Fuel for your workday 

• A fully stocked kitchen with free snacks and beverages – we keep you energized and ready for what’s next.  

Grow with us 

• Ongoing professional development resources, training, and mentorship programs to help you build your care and grow within Forge.