Our Operations Team in Ghent is looking for a passionate CAR-T Operations Junior Expert. Do you want a meaningful job? Here you contribute to the fight against cancer every day!

What Can You Expect?

The role of a CAR-T Operations Junior Expert is exciting and challenging. Here's what you'll do: 

• Perform CAR-T process activities: You will accurately perform various steps in the CAR-T manufacturing process. From cell culture and purification to aseptic processing and cryopreservation, you will ensure the highest quality and safety standards in the clean room. 
• Compliance with quality standards: You will closely follow Standard Operating Procedures (SOPs) and batch records to ensure the quality and safety of our cellular therapies. 
• Collaboration: You will work closely with various teams and departments to complete production tasks according to a shift schedule. 
• Innovate and improve: You will contribute to process optimizations and efficiency improvements. 
• Environmental monitoring: You will maintain GMP production areas, focusing on equipment cleanliness and environmental monitoring.
• GMP documentation: You will complete all necessary GMP documents to ensure compliance and traceability.

Who Are We Looking For? 

Education

• You have at least a bachelor's degree in sciences, (bio)engineering, biotechnology, pharmacy or another related field of study or you are equivalent through experience. 

Experience

• Practical experience within a cGMP or ATMP environment and with aseptic techniques in clean rooms is certainly an asset but not a must. In any case, we offer you the necessary training so that you can get started smoothly in your new role.    
• Proficiency with Microsoft Office tools (Word, Excel, PowerPoint, and Outlook) is required. 

Languages

• You are fluent in Dutch or English, with strong oral and written communication skills. 

Strengths

• You are a true team player but also enjoy working independently. You have strong interpersonal skills and a healthy dose of empathy. You are flexible, problem-solving and can multitask well. You have a strong desire to learn and grow. 
• You bring a hands-on mindset paired with a strong focus on quality and detail.

What Do We Offer?  

• A meaningful job that contributes directly to the well-being of patients. 
• An excellent work-life balance. You work 4 days. Then you enjoy 4 days off.
• A supportive and innovative work environment. We value and encourage learning and personal development. 
• The opportunity to work with people from all over the world.
• An open-ended contract and an attractive salary package complemented by many fringe benefits, such as additional statutory vacations, meal vouchers, group and hospitalization insurance, double vacation pay, an end-of-year and performance bonus.
• Many fun and informal events.  

About Legend Biotech

Legend Biotech is a global biotechnology company dedicated to developing, manufacturing, and commercializing innovative and life-saving cell therapies for the treatment of chronic and life-threatening diseases, such as cancer. 

The company was founded in 2014 and is headquartered in Somerset, New Jersey. Legend Biotech now employs over 2,400 people across six global manufacturing sites. Two of these sites are in Ghent: Obelisc (Technology Park Zwijnaarde) and Tech Lane (Eilandje Zwijnaarde). 

In Ghent, Legend Biotech focuses on the production of advanced CAR-T cell therapies for the treatment of multiple myeloma, in close collaboration with Johnson & Johnson. 

#LI-AG1

Want to Make a Real Impact? Join Our QA Document Control Specialist Talent Pool!

The Quality Assurance Document Control Specialist role is a position with responsibilities for supporting the document management process within a cell therapy manufacturing facility to support both clinical and commercial requirements in a sterile GMP environment. This role will ensure compliance within the document management system, document storage and retention, and document issuance and reconciliation.

What can you expect?

• Responsible for managing the document control systems and processes for the site.
• Serve as a Document Control reviewer for new and revised procedures and documents to ensure compliance with global and site procedures.
• Support Document Management system users with workflow handling and electronic system usage.
• Manage the periodic review process for procedures.
• Issuance of batch related documentation in support of GMP manufacturing.
• Reconcile GMP documentation following document lifecycle requirements.
• Creation and issuance of GMP logbooks.
• Responsible for storage and archival of GMP documents and batch related records.
• Perform tasks in a manner consistent with the safety policies, quality systems and cGMP requirements.
• Review and approve SOPs, and other documentation.
• Drive continuous improvement.
• Have advanced computer skills to increase department's productivity, as well as broadening technical and scientific knowledge.

Who are we looking for?

Education: 

• You are an undergrad, have a secondary degree or equivalent through experience.

Experience:

• Not required.
• It is preferable that the candidate has experience working in a GMP environment, but this is not a must.

Language:

• Dutch and technical English

Strengths: 

What do we offer you? 

• A meaningful job with an excellent work-life balance. You will work 4 days, followed by 4 days at home.
• A supportive and innovative work environment that encourages learning and personal development. 
• The opportunity to work with people from all over the world. 
• You start working through interim contracts. After 6 months you'll receive a permanent contract.
• An attractive salary package with numerous benefits, including additional statutory vacations, meal vouchers of €7/day , group and hospitalization insurance once you start your permanent contract, double vacation pay, and performance bonuses. 

About Legend Biotech

Legend Biotech is a global biotechnology company dedicated to developing, manufacturing, and commercializing innovative and life-saving cell therapies for the treatment of chronic and life-threatening diseases, such as cancer. 

The company was founded in 2014 and is headquartered in Somerset, New Jersey. Legend Biotech now employs over 2,400 people across six global manufacturing sites. Two of these sites are in Ghent: Obelisc (Technology Park Zwijnaarde) and Tech Lane (Eilandje Zwijnaarde). 

In Ghent, Legend Biotech focuses on the production of advanced CAR-T cell therapies for the treatment of multiple myeloma, in close collaboration with Johnson & Johnson. 

#LI-AG1

As Quality Control Manager Techlane, you will balance ramp‑up activities with routine QC operations, while continuously improving efficiency, developing your team, and strengthening laboratory performance. You will combine scientific expertise with people leadership to ensure robust, compliant, and future-ready QC operations in a highly regulated cGMP environment. This role offers the opportunity to make a tangible impact on product quality, patient safety, and the continued growth of our organization, while driving continuous improvement initiatives and mindset.

What can you expect?

Here’s what you’ll do:

• Lead, coach, and develop QC laboratory associates, including hiring and performance management
• Ensure appropriate training in cGMP, safety, and technical competencies
• Oversee QC testing activities
• Review and approve laboratory data, test methods, and procedures
• Lead and support laboratory investigations (events, deviations, invalid assays)
• Ensure maintenance, calibration, and qualification of laboratory equipment
• Drive test method verification, qualification, validation, and transfer activities
• Act as a subject matter expert in troubleshooting complex laboratory issues
• Collaborate closely with Quality Assurance, Manufacturing, Engineering, MSAT, and Maintenance
• Manage departmental resources, budgets, and staffing plans
• Contribute to global QC laboratory strategies aligned with compliance and business objectives
• Drive continuous improvement and lead improvement projects.

Who are we looking for?

Education

• Bachelor’s degree (minimum) in a scientific or technical field, such as Life Sciences, Chemistry, Biochemistry, Biotechnology, Microbiology, Pharmaceutical Sciences, or a related discipline.

Experience

• 8-10 years of relevant experience in a regulated pharmaceutical, biotech, or cell therapy environment
• 5+ years of proven people leadership experience
• Experience in aseptic manufacturing is strongly preferred
• Hands-on experience with quality systems and regulatory requirements
• Familiarity with Eudralex, ICH and 21 CFR.

Languages

• Fluent in Dutch and English

Strengths

• Strong leadership and people management skills
• Excellent interpersonal, written, and verbal communication abilities
• Highly organized, proactive, and solution-oriented
• Able to manage multiple priorities in a fast-paced environment
• Comfortable making critical decisions with limited information

Expertise

• EU/FDA guidance for cell-based products and cGMP regulations
• Chemical, biochemical, and microbiological concepts
• Aseptic processing in ISO 5 cleanrooms and biosafety cabinets
• Process excellence tools and continuous improvement methodologies

What do we offer you? 

• A meaningful job with a good work-life balance.
• A supportive and innovative work environment. We value and encourage learning and personal development.
• The opportunity to work with people from all over the world.
• A contract of indefinite duration and an attractive salary package complemented by many fringe benefits, such as additional statutory vacations, a company car, meal vouchers, group and hospitalization insurance, double vacation pay, an end-of-year and performance bonus.
• Many fun and informal events.

About Legend Biotech

Legend Biotech is a global biotechnology company dedicated to developing, manufacturing, and commercializing innovative and life-saving cell therapies for the treatment of chronic and life-threatening diseases, such as cancer.

The company was founded in 2014 and is headquartered in Somerset, New Jersey. Legend Biotech now employs over 2,400 people across six global manufacturing sites. Two of these sites are in Ghent: Obelisc (Technology Park Zwijnaarde) and Tech Lane (Eilandje Zwijnaarde).

In Ghent, Legend Biotech focuses on the production of advanced CAR-T cell therapies for the treatment of multiple myeloma, in close collaboration with Johnson & Johnson.

Lead where it matters most.

At Legend Biotech, leadership is about people first. About trust. Growth. Responsibility. And impact you can truly feel.
At our CAR-T manufacturing sites Obelisc and Tech Lane in Ghent, we are looking for experienced Supervisors who get energy from coaching people, leading teams and helping others grow into their best selves.

We are hiring Supervisors in CAR-T Production, Quality Control (QC) and Maintenance. Three different domains, one shared purpose: helping life-saving therapies reach patients safely, reliably and on time.
This is a leadership role where your way of working shapes people, teams, and outcomes. 

What can you expect?

As a supervisor, you lead where it truly matters: on the floor, with your team. 

Your focus is clear:

• Coaching and people management:
  You lead a team of operators, analysts or technicians. You coach, support and challenge people to grow, take ownership and perform with confidence.
• Creating structure and clarity:
  You bring calm and focus to a complex environment. You set priorities, align expectations and create a safe space where people can excel.
• Quality and responsibility:
  You safeguard GMP, safety and compliance through daily leadership, not paperwork alone. You lead by example and build a strong quality mindset in your team.
• Keeping the operation moving:
  You oversee daily activities, anticipate issues and act when it matters. You work closely with other teams to solve problems and keep processes running. 

Through your leadership, teams grow, processes stay on track and patients receive the therapies they are waiting for. 

Who are we looking for?

Education

• A bachelor's or master's degree in a relevant field, such as science, bioengineering or pharmacy (for Production or QC), or engineering or technical discipline (for Maintenance), or equivalent experience. 

Experience

• You have experience in either Production, Quality Control or Maintenance within a GMP or ATMP environment in pharma or biotech.
• You either bring leadership experience or the clear ambition to grow into a people management role. 

Languages

• You are fluent in English, both spoken and written.
• Knowledge of Dutch is a plus.

Strengths

• You genuinely enjoy leading and developing people.
• You communicate clearly, listen actively and give constructive feedback.
• You create trust, ownership and motivation in your team.
• You stay calm, structured and decisive in a dynamic environment.

Expertise

• You bring a strong quality and compliance mindset.
• You work comfortably with procedures, documentation, and systems.
• You are hands-on, solution-oriented, and driven by people and teamwork. 

What do we offer you?

• A meaningful job with an excellent work-life balance. You will work 4 days. After that you will enjoy 4 days off.
• A supportive and innovative work environment. We value and encourage learning and personal development.
• The opportunity to work with people from all over the world.
• A contract of indefinite duration and an attractive salary package complemented by many fringe benefits, such as additional statutory vacations, meal vouchers, group and hospitalization insurance, double vacation pay, an end-of-year and performance bonus.
• Many fun and informal events.

Does this feel like your next step?

If you want to lead people, build strong teams, and make a difference where it truly counts, we would love to meet you. Apply today and lead where it matters most. 

About Legend Biotech

With over 2,900 employees worldwide, Legend Biotech is the largest standalone cell therapy company and a pioneer in treatments that are changing cancer care for good. We develop and market the CAR-T cell therapy ciltacabtagene autoleucel (cilta-cel) in partnership with ohnson & Johnson. In the EU, cilta-cel is approved under the brand name CARVYKTI® for the treatment of adult patients with relapsed and refractory multiple myeloma who have received at least one prior line of therapy.

Legend Biotech is a fully integrated global organization with manufacturing sites in the United States and Europe. From our sites in Ghent, Belgium, our teams support the clinical and commercial supply of CAR-T therapies across the EMEA region, translating advanced science into real-world impact for patients.

What sets us apart is clarity of purpose. At Legend Biotech Europe, everyone understands how their role contributes to our mission and how their daily work helps bring life-changing therapies to patients who need them most.