THE OPPORTUNITY

Vir Biotechnology is looking for a Senior Accountant to play a critical role in our monthly and quarterly close processes. You will own complex accruals and balance sheet areas, partner cross‑functionally to resolve issues, and help ensure the accuracy and integrity of our financial reporting in a SOX‑compliant environment. This is a hands‑on role with meaningful ownership, ideal for someone who enjoys digging into the details while continuously improving close processes.

This role reports to the Sr. Director, Accounting Operations and is located in our San Francisco headquarters with an expectation of 3 days per week in office.

WHAT YOU'LL DO

• Own the preparation and review of monthly and quarterly journal entries, including G&A accruals (legal, professional services, facilities, software subscriptions), cash and investments, depreciation, amortization, and prepaid expense activity
• Manage balance sheet reconciliations for assigned areas such as cash and investments, prepaids, fixed assets, and accrued G&A services, investigating variances and resolving issues
• Maintain and review prepaid amortization schedules in FloQast, including short‑term and long‑term classifications and review for unpaid prepaid adjustments
• Support PO‑based accruals across G&A, facilities, subscriptions, and PP&E categories, ensuring accurate period‑end cut‑off
• Prepare fixed assets rollforward
• Provide Accounts Payable coverage as needed, including invoice processing, Coupa review for accruals, and AP accrual support during close
• Support SOX controls and audits by preparing documentation, tie‑outs, and responding to internal and external audit requests
• Compile and review monthly headcount reporting and serve as a key point of contact for your assigned close areas
• Identify opportunities to improve close efficiency, documentation, and processes

WHO YOU ARE AND WHAT YOU BRING

• Bachelor’s degree in Accounting or Finance (CPA a plus)
• 5+ years of progressive accounting experience, including month‑end and quarter‑end close in a SOX environment
• Strong knowledge of accrual accounting, prepaids, fixed assets, and P&L analysis
• Proven ability to independently own close areas, investigate discrepancies, and exercise sound judgment
• Experience with NetSuite, Coupa, and FloQast (preferred)
• Advanced Excel skills, including pivot tables, lookups, and structured schedules

THE OPPORTUNITY

Vir Biotechnology is looking for a Research Associate II to join our growing in vivo team. In this role you will independently conduct experiments in mouse models of cancer to advance therapeutic candidates toward clinical trials.

This role is located in our San Francisco headquarters with an expectation of 4 days per week in office.

WHAT YOU'LL DO

• Perform in-vivo efficacy, PK, and PD studies in animal models of cancer, including tumor implantation, tumor/body weight measurement, compound administration, and biological sample collection
• Collect, organize, and analyze experimental data accurately and maintain laboratory records in compliance with company protocols and regulatory standards
• Interact with in vivo and cross-functional teams through meetings and ad-hoc interactions

WHO YOU ARE AND WHAT YOU BRING

• Bachelor’s degree in biological sciences or related field with 2+ years of direct in vivo research experience
• Proficiency in mouse handling, tumor measurement, dosing (IV, IP, and SQ injections), and blood sampling is required
• Candidates with experience in both syngeneic and xenograft models of cancer are preferred
• Proficiency in mouse necropsy, perfusion, and aseptic cell culture is preferred
• Strong communication, critical thinking, and interpersonal skills

THE OPPORTUNITY

Vir Biotechnology seeks a Vice President, Strategy & Portfolio Planning, reporting to the Chief Business Officer, who will be responsible for guiding the company's strategy and optimizing its portfolio of programs products, and partnerships. This visible leadership position works across all business units.

You will serve as a thoughtful strategic partner to the CBO and executive leadership team, driving corporate strategy and portfolio prioritization. You will optimize Vir Bio's business, translate enterprise-level strategies into actions, and align the organization to the strategy. Working closely with competitive intelligence, business development, and alliance management CBO sub-teams, you will develop Vir Bio's long-term strategic plan and lead integrated asset-level strategies across clinical and preclinical-stage programs. An enterprise leader, you will apply analytical rigor, translate complex clinical, scientific, and financial data into clear recommendations, articulate strategy, and work collaboratively across the company.

You’ll thrive in this role if you love shaping big-picture strategy in fast-moving biotech environments, get energized by steering clinical-stage portfolios to provide the greatest patient benefit, and leveraging your experience across organizations both large and small.

This role is in our San Francisco headquarters with at least 3 days per week in the office.

WHAT YOU'LL DO

Corporate Strategy

• Lead the development and evolution of Vir Bio's long-term strategic plan in partnership with the CBO, executive leadership, and Board of Directors
• Adapt corporate strategy in response to emerging clinical data, evolving market dynamics, and competitive landscape shifts
• Working closely with the CEO, CBO, and CEO Chief of Staff, conceptualize and create board materials for quarterly board meetings and strategic offsites
• Drive scenario planning and options analysis to inform critical business decisions and enable agile executive team decision-making
• Contribute to investor communications and narratives supporting company growth
• Design and manage strategic planning cycles, leadership meetings, and governance forums to enable clear priorities, decision-making, and execution tracking

Portfolio Planning  

• Partner with the CBO and executive leadership to shape Vir Bio's long-term portfolio strategy, evaluating diversification pathways and strategic options under different capital, partnership, and market scenarios
• Define portfolio strategy frameworks and valuation methodologies (NPV analysis, risk-adjusted valuations, scenario modeling) that inform corporate development priorities, investment decisions, and strategic prioritization
• Develop and implement analytical frameworks and decision-making tools (including those leveraging AI/ML) that enhance organizational capabilities, driving data-driven strategic maturity and alignment across the organization
• Conduct portfolio-level strategic analysis to identify gaps, optimize risk profile, and maximize financial returns, influencing business development target identification and deal thesis development in close partnership with senior leadership
• Establish portfolio metrics, KPIs, and measurement frameworks to evaluate performance against strategic objectives, integrating competitive intelligence, emerging clinical data, and market insights into decision-making
• Engage external advisors, consultants, and KOLs to inform portfolio strategy and validate strategic assumptions

WHO YOU ARE AND WHAT YOU BRING

• BA/BS with 20+ years, MS/MBA with 18+ years, or PhD with 15+ years of progressive pharmaceutical or life sciences experience in senior leadership roles; experience in infectious disease and/or oncology highly preferred
• Proven track record in corporate strategy development, portfolio management, and strategic execution within or for large and small biopharmas
• Biopharma strategy consulting experience, preferably with one of the premier management consulting firms preferred
• Experience leading integrated strategy across clinical-stage programs, including portfolio prioritization, development planning, and commercial positioning
• Expertise in financial modeling, valuation methodologies (DCF, NPV, risk-adjusted valuations), and portfolio analytics
• Experience delivering strategic initiatives through governance processes and managing ambiguity

THE OPPORTUNITY

Vir Biotechnology is looking for an experienced Sr. Director of Clinical Pharmacology and Translational PK/PD to lead the technical and operational aspects of the department in support of programs across all stages of preclinical and clinical development. You will work across Vir Bio's portfolio of infectious disease and oncology programs, providing hands-on leadership while managing and developing a team. In this role, you will work collaboratively with internal and external cross-functional teams and consultants to support the successful and timely advancement of drug development programs. You will evaluate and apply best practices and innovative techniques to foster successful execution and outcomes of clinical studies. You will report to the VP of Translational Development.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

WHAT YOU'LL DO

• Oversee clinical pharmacology and translational PK/PD operations and deliverables across all stages of development for both infectious disease and oncology programs
• Represent clinical pharmacology and translational PK/PD as technical expert on cross-functional project teams and provide strategic input to program advancement
• Develop fit-for-purpose clinical pharmacology strategies to enable development and regulatory decisions from pre-IND through market authorization
• Select and execute appropriate modeling and simulation approaches (PK/PD, PopPK, exposure-response) to inform dose selection, optimization, and justification for Phase 2 and pivotal trials
• Author and provide technical input for regulatory documents and submissions (protocols, IBs, briefing packages, INDs, NDAs/BLAs) and responses to questions
• Work collaboratively with cross-functional teams, including clinical research, clinical operations, biomarkers, bioanalytical, biometrics, CMC, research, and regulatory in support of program advancement
• Establish and manage collaborations with external vendors and collaborating partners
• Generate and manage departmental budget(s) and optimize resource allocation across multiple programs
• Manage and develop the Clinical Pharmacology and Translational PK/PD team, including hiring, mentoring, and building departmental capabilities to support organizational needs

WHO YOU ARE AND WHAT YOU BRING

• PhD, PharmD, or MD with relevant training in clinical pharmacology, pharmacokinetics, pharmaceutics, or related field with 13+ years industry experience in Clinical Pharmacology, DMPK and/or related fields
• Mastery of nonclinical and clinical pharmacokinetic concepts and methodologies with deep understanding of multidisciplinary drug development requirements
• Expertise in PK/PD, PopPK and exposure-response modeling with proficiency in R and extensive hands-on experience with Monolix or NONMEM
• Extensive experience leading translational and clinical pharmacology work from FIH dose selection through market authorization
• Strong understanding of regulatory requirements and experience contributing to regulatory submissions and engagements
• Working knowledge of bioanalytical techniques in support of clinical development of small molecules and biologics
• Experience with biologics, including monoclonal antibodies and bispecifics required; experience in oncology and/or infectious disease indications strongly preferred
• Proficiency using standard PK analysis and graphing programs (Phoenix WNL, Graphpad, R, etc.)
• Proven ability to manage and develop teams

THE OPPORTUNITY

Vir Biotechnology is looking for a Regulatory Affairs Manager to join the regulatory group. The successful candidate, under the guidance of experienced regulatory affairs professionals, will be responsible for the coordination and preparation of documents intended for regulatory submissions for new and mature products (as applicable) to ensure alignment and compliance with local and regional registration requirements as well as with company policies.

This role is based in San Francisco and requires 3 days a week onsite.

WHAT YOU'LL DO

• you will represent Regulatory Affairs on cross-functional project teams with the following responsibilities:
• Coordinate documents intended for regulatory submissions, manage internal reviews and resulting input from cross‑functional team members for products in line with ICH and regional requirements, meets scientific rigor and company policies and procedures
• Ensures quality and regulatory standards are considered and upheld throughout the product development life cycle
• Assists with the coordination and tracking of regulatory commitments and submission plans for maintenance activities such as INDs/CTAs, annual reports, periodic safety reports, protocol submissions, and key regulatory filings
• Participates in group meetings and provides tactical approaches to addressing issues of moderate complexity
• Participate in the development of processes and procedures relevant to regulatory functions
• Performs document filing and retrieval functions as directed, or in conjunction with departmental SOPs

WHO YOU ARE AND WHAT YOU BRING

• BS and 8+ years of Experience, MS and 6+ years of experience with a minimum of 5+ years of regulatory experience
• Working knowledge of US FDA regulations (ex-US is a plus) and industry standards pertaining to regulatory
• Knowledge of the drug development process and eCTD
• Excellent organization skills and ability to work on multiple projects with tight timelines
• Excellent verbal and written communication skills and interpersonal skills

THE OPPORTUNITY

Vir Bio is looking for a Senior Director, Alliance Management, to provide strategic leadership for a portfolio of high‑value external partnerships, including Vir Bio’s commercial hepatitis delta collaboration with Norgine across Europe, Australia, and New Zealand. This role operates with broad autonomy and accountability for alliance performance and value realization.

You will serve as a senior enterprise leader for certain alliances, partnering closely with cross‑functional executives to shape strategy, establish effective governance, and ensure disciplined execution across the alliance lifecycle. This role is accountable for maximizing the strategic, operational, and financial value of their portfolio of partnered assets through proactive leadership, risk management, and issue resolution.

As the primary executive interface for assigned partners, you will own alliance health, execution against Definitive Agreements (DAs), and long‑term relationship outcomes, including amendment strategy and exit planning.

This role is located in our San Francisco headquarters with an expectation of at least 3 days per week in office.

WHAT YOU'LL DO

• Provide strategic leadership for a portfolio of alliances spanning clinical collaborations, co‑development partnerships, and commercial agreements, with accountability for overall alliance performance and value delivery.
• Establish and lead fit‑for‑purpose governance models; chair and orchestrate joint governance forums and cross‑company teams to align priorities, enable decision‑making, and drive execution.
• Define and maintain a clear strategic intent and multi‑year operating plan for each alliance, ensuring alignment with Vir Bio’s portfolio strategy and regular communication to senior stakeholders.
• Serve as the senior point of accountability for partner relationships within the assigned portfolio, setting the tone for collaboration, trust, and performance; proactively address relationship risks and escalation topics.
• Own oversight of financial and non‑financial obligations, including leadership of quarterly partner financial reviews, forecasting, and variance analysis in close partnership with Finance.
• Ensure disciplined execution against all contractual obligations, including milestones, payments, supply commitments, and performance terms, with timely identification and mitigation of execution risks.
• Lead partner negotiations related to agreement amendments, extensions, and terminations, in collaboration with Legal, BD, and functional leadership.
• Anticipate and manage complex alliance challenges arising from contractual interpretation, strategic misalignment, or operational dependencies, applying sound judgment and enterprise perspective.
• Drive continuous improvement in alliance effectiveness by conducting structured alliance health assessments and translating insights into concrete actions that enhance value realization.

WHO YOU ARE AND WHAT YOU BRING

• BA/BS with 18+ years, MS/MBA with 16+ years, or PhD with 13+ years of progressive pharmaceutical or life sciences experience in senior leadership roles
• 8+ years of experience in Alliance Management and/or Partnering within a biotech or pharmaceutical organization, managing complex, high‑value partnerships.
• Proven experience leading alliances involving late‑stage development assets, with additional experience supporting commercial‑stage products and launches.
• Strong command of development, commercialization, and collaboration agreements, with the ability to interpret, negotiate, and operationalize complex contractual terms.
• Demonstrated ability to lead through influence in a highly matrixed environment and to partner effectively with senior executives across functions and organizations.
• Strong strategic, analytical, and problem‑solving capabilities, with consistent application of sound business judgment.
• Collaborative leadership style with the ability to build alignment, drive decisions, and hold teams accountable.
• Comfortable operating in a fast‑paced, evolving environment with high ambiguity and enterprise‑level visibility.
• Experience in the fields of infectious diseases and oncology preferred.

THE OPPORTUNITY

Reporting to the Chief Medical Officer, or CMO, the SVP Oncology Therapeutic Area Head, or TA Head, will be responsible for overseeing the successful development of multiple molecules for the treatment of cancer in Vir Biotechnology's oncology portfolio. The Oncology TA Head will lead the oncology strategy and lead a cross-functional clinical team to develop novel therapeutics from IND through marketing application and registration.  This will include guidance and oversight of clinical development strategies for multiple programs and provision of expert input to clinical developability of pre-clinical assets in the oncology pipeline.  The TA head will be a key partner for the Research Organization and will provide clinical and strategic leadership for programs in Discovery through IND filing.  The TA Head will also be a key partner for business development in oncology. 

This role is located at Vir Bio’s San Francisco headquarters with an expectation of 3 days per week in the office.

WHAT YOU'LL DO

• Lead Vir Bio's Oncology clinical development strategy to deliver registrational data to health authorities for evaluation and, ultimately, to patients and the oncologists who care for them.
• Oversee activities to ensure appropriate objectives and resources are deployed to deliver on key milestones to advance the company’s oncology assets in development.
• Coach and mentor program team leaders, clinical scientists and medical monitors.
• Collaborate with Regulatory Sciences to shape the regulatory strategy for oncology clinical development programs and play a key role in representing the Company in health authority interactions
• Core member of the CMO Organization Leadership Team
• Responsible for collaborating with stakeholders across Vir Bio and with external partners, including potential joint development steering committees, to shape the strategy and efficient advancement of molecules throughout clinical development.
• At major congresses, and as needed, represent the Company and the science to various internal and external stakeholders (including the Board of Directors, clinical investigators, KOLs, patient advocacy groups, investors, and analysts).

WHO YOU ARE AND WHAT YOU BRING

A highly experienced, collaborative, and innovative leader with extensive clinical drug development experience will thrive in this role.  A successful candidate will demonstrate strategic and technical prowess, build strong working relationships, and have an entrepreneurial spirit.  Specific qualifications include:

• M.D. with specialty training in Oncology required
• Minimum 12+ years of experience in early and late-stage clinical development at biotech or pharmaceutical company required
• Demonstrated track record applying strategic context to development planning, ability to balance risk and make trade-offs to advance the portfolio priorities
• A high degree of business acumen, a big-picture perspective, and the ability to galvanize a team around a common goal
• Demonstrated track record of accountability, scientific rigor, and innovation
• Ability to build teams and a culture that nourishes creativity, scientific curiosity, with integrity and respect across functions and layers within the Company
• An outcome-driven mindset and a commitment to achieving key milestones
• Exceptional interpersonal and communication skills able to clearly convey complex medical and scientific information to a wide range of internal and external audien