The Opportunity:

The Senior Director, Commercial, UK is responsible for defining and executing the local commercial strategy for oncology products. This role is accountable for building the commercial organization, driving launch and growth performance, and ensuring strong alignment across Medical Affairs, Market Access, and other key functions.

The incumbent needs to proactively recognize and address relevant systemic (e.g. health care structures, competitors, data gaps, diagnostic challenges, missing advocacy) and HCP related opportunities (e.g. therapeutic gaps, differentiation, economical attributes, clear messaging of patient- and physician relevant benefits). The Senior Director Commercial will further oversee the generation of insights from the therapeutic field, and translate these insights into a comprehensive, cross-functional strategy. Supporting a clear positioning and aligned communication approach, the incumbent will in addition secure the development and implementation of tactics and tools for the field force to effectively address customer needs.

Responsibilities:

• Act as the Commercial Lead for UK accountable for local commercial strategy, execution, and performance across the oncology portfolio.

• Serve as a core member of the UK Leadership Team, contributing Italy strategy, launch planning, and business decisions.

• Partner with regional and local Medical Affairs and Marketing Team to translate clinical and economic evidence into compelling value communications tailored for UK stakeholders including HCPs and payers.

• Translate regional commercial strategy into locally optimized plans aligned with market dynamics, customer needs, and healthcare system requirements.

• Translate regional commercial strategy into locally optimized plans aligned with market dynamics, customer needs, and healthcare system requirements in close collaboration with the ED Marketing, Europe.

• Collaborate with regional commercial teams by representing the country and contributing to commercial plans shaping our strategy.

• Develop and execute country-level brand and portfolio strategies across pre-launch, launch, and post-launch phases.

• Drive demand generation and appropriate use through non-promotional and promotional channels in compliance with local regulations.

• Lead forecasting, budgeting, and operational planning for the country in close collaboration with the ED, Commercial Excellence, Business Analytics and Insights, Europe.

• Lead commercial launch readiness for oncology products, including customer strategy, segmentation, targeting, and field force planning.

• Partner closely with Medical Affairs and Market Access to ensure integrated launch execution and consistent external engagement.

• Monitor performance, competitive dynamics, and market trends, adjusting strategy as needed.

• Oversee customer engagement strategy across key stakeholders, including oncologists, treatment centers, and healthcare organizations.

• Ensure effective field force deployment and capability building (e.g., sales, key account management, customer-facing roles).

• Work closely with Medical Affairs, Market Access, Regulatory, Finance, Corporate Affairs and other support functions to ensure aligned and compliant country execution.

• Ensure strong integration of commercial plans with access, medical, and evidence strategies.

• Build, lead, and develop the country commercial organization, including sales, marketing, and customer-facing roles as the business scales.

• Establish commercial processes, governance, and ways of working as part of the country build-out.

• Foster a culture of accountability, collaboration, and performance excellence.

• Contribute to regional and country-specific initiatives.

• Travel nationally and internationally.

Required Skills, Experience and Education:

• Advanced degree required (e.g., MSc, PhD, MD, PharmD). 

• 10+ years of experience in pharmaceutical or biotech commercial roles.

• Significant experience in oncology commercial leadership at country level.

• Proven track record of successful oncology product launches in UK and successful HCP / KOL interactions.

• Proven project management experience.

• Excellent communication skills, both in person and virtual.

• Scientific and solution-orientated mindset and capability to move and execute in a rapidly changing, ambiguous environment.

• Strong understanding of local healthcare systems, customer dynamics, and reimbursement environments.

• Experience in a US-based or global biotech and/or in a build-out or first-in-country role strongly preferred.

• Proven leadership and people management capabilities; demonstrated success in small but fast growing, entrepreneurial commercial environment.

• High capacity of social competence for teamwork, coaching and situational leadership.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. 

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The Opportunity:

Reporting to the VP, General Manager, UK the Senior Director, Medical Affairs, UK is the medical leader responsible for defining and executing the local medical strategy for oncology products. This role serves as the medical voice within the UK Leadership Team, ensuring scientific excellence, compliant medical engagement, and strong alignment between global strategy and local patient, physician, and healthcare system needs.

This leader will ensure that UK medical considerations are embedded in the regional medical strategy and plans and will partner with the General Manager and crossfunctional teams, as well as the VP, Head of Europe Medical Affairs and their leadership team. The incumbent will contribute to building the UK medical team and work closely with the Global and Regional Medical Affairs teams across Med Affairs functions.

Responsibilities:

• Act as the Medical Affairs lead for UK, accountable for local medical strategy, execution, and impact across the oncology portfolio.

• Translate global medical and clinical strategies into locally relevant medical plans aligned with UK regulations and clinical practice.

• Build and maintain strong relationships with national and regional key opinion leaders, oncology networks, academic institutions, and scientific societies.

• Lead scientific exchange, advisory boards, investigator and other external meetings, press conferences, and congress engagement at country level.

• Serve as medical expert within the local oncology and scientific community, acting as a spokesperson for UK.

• Collaborate effectively with regional and global teams by contributing to overall medical affairs strategy, strongly partnering with local, regional and global clinical development and operations teams.

• Drive local medical strategy across pre-launch, launch, and post-launch phases.

• Provide local medical expertise on evidence generation activities including local studies, real-world evidence initiatives, and investigator-initiated research (where permitted).

• Ensure effective execution of publication plans and scientific communication activities.

• Lead medical launch readiness for oncology products, including training, scientific materials, and field medical engagement plans.

• Partner with Market Access and Commercial teams to support value communication and reimbursement-related interactions from a medical perspective, e.g. representing and defining evidence and value of innovation at oral HTA hearings.

• Support lifecycle management activities including new indications, label updates, and competitive positioning.

• Work closely with Market Access, Commercial, Regulatory, Safety, and Corporate Affairs teams to ensure aligned and compliant execution of country plans.

• Provide medical review and approval of non-promotional materials in accordance with local regulations and company policies.

• Build, lead, and develop the UK Medical Affairs team, including Medical Directors and Medical Science Liaisons.

• Establish medical processes, governance, and ways of working as part of the UK build-out.

• Foster a culture of scientific rigor, compliance, and collaboration.

• Ensure all medical activities comply with local regulations, national and EFPIA codes, and internal company policies.

• Represent Medical Affairs in UK governance and risk management forums.

Required Skills, Experience and Education:

• Advanced degree required (MD, PhD, or PharmD).

• Strong background and experience in oncology required.

• 10+ years’ experience in Medical Affairs with a track record of country leadership.

• Proven value and benefit assessment experience, with deep understanding of country payer decision-making.

• Strong stakeholder management and ability to collaborate with internal and external partners.

• Proven experience supporting oncology product launches in a European market.

• Strong understanding of the local healthcare system, clinical practice, and regulatory environment.

• Experience in a US-based or global biotech and/or in a build-out or first-in-country role strongly.

• Excellent communication skills, both in person and virtual.

• Proven leadership and people management capabilities; demonstrated success in small but fast growing, entrepreneurial environment.

• Scientific and solution-orientated mindset and capability to move and execute in a rapidly changing, ambiguous environment.

• Strong understanding of local healthcare systems, customer dynamics, and reimbursement environments.

• Willingness to travel nationally and internationally.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. 

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The Opportunity:

The Senior Director, Market Access is responsible for defining and executing the country market access strategy to ensure timely, sustainable patient access to innovative oncology therapies. This role shapes reimbursement and access strategy, drives value demonstration, and leads engagement with key external stakeholders including payers, HTA bodies, and health authorities.

This position will partner with commercial and medical affairs teams to deliver launch activities by providing access insights, developing evidence-based HTA, Pricing & Reimbursement dossiers and tools, engaging with market access and public affairs stakeholders as well as driving pricing strategy activities, and lead the activities to deliver access results supporting the overall success of the product launches.

Responsibilities:

• Lead Market Access & Reimbursement: Develop and implement strategies to support access and pricing decisions for oncology products within the UK healthcare system.

• HTA & Pricing Filings: Lead preparation and submission of value dossiers, benefit assessments (e.g., AMNOG/G-BA, HAS, AIFA…) and pricing negotiations with statutory health insurance decision makers (e.g., GKV-SV, CEPS…).

• Partner with regional and local Medical Affairs and Marketing team to translate clinical and economic evidence into compelling value communications tailored for UK payers.

• Build and maintain strong relationships with key external stakeholders (payers, HTA authorities, policy influencers). Representation of Revolution Medicines at local trade associations for market access subjects.

• Work with regional EU Market Access teams to align local access strategy with broader European and corporate objectives, especially in terms of aligning the European regulatory and JCA strategy and execution with local value dossier submission and pricing negotiation strategy. Provide early market access input to regional and EU clinical development and medical teams.

• Lead negotiation with all levels of national payers.

• Develop innovative pricing and value based contracting models to optimize the acceleration of reimbursement approvals.

• Policy Monitoring: Monitor health policy developments, HTA processes and local reimbursement environments to inform strategy.

• Represent Market Access in Country Leadership Team meetings and contribute to overall business strategy.

• Drive access and value related projects such as landscape assessments, payer market research, payer advisory boards and general guidance on local strategies.

• Development of outreach and engagement plan for key payers creating and maintaining a strong network.

• Create and lead a market access team, including coaching, performance management, and talent development when a team is in place.

• Early access planning of new products and indications, drive launch readiness for multiple oncology assets (portfolio responsibility).

• Influence EU / regional access strategy based on local payer insights from a leadership position

• Travel nationally and internationally.

Required Skills, Experience and Education:

• Advanced degree (e.g., Life Sciences, Pharmacy, Health Economics, Public Health).

• A minimum of 10 years’ experience in market access, pricing, reimbursement or health economics (Pharma/Biotech).

• Proven value and benefit assessment experience, with deep understanding of country payer decision-making.

• Demonstrated success and experience supporting oncology product pre-launch, launch and post launch in UK.

• Demonstrated success in negotiating pricing and reimbursement conditions with public administrations and health authorities.

• Strong stakeholder management and ability to collaborate with internal and external partners.

• Excellent interpersonal and communication skills.

• Scientific and solution-orientated mindset and capability to move and execute in a rapidly changing, ambiguous environment.

• Strong understanding of local healthcare systems, customer dynamics, and reimbursement environments.

• Experience in a biotech and/or in a build-out or first-in-country role strongly preferred.

• Proven leadership and people management capabilities; demonstrated success in small but fast growing, entrepreneurial commercial environment.

• High capacity of social competence for teamwork, coaching and situational leadership.

Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com. 

#LI-Remote #LI-MP1