At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

Under the direction of the department supervisor, technical/clinical consultant, and laboratory director, the Histotechnician 2 will be responsible for processing FFPE specimens for microscopic evaluation to support our molecular diagnostics test offerings.

Available Shifts:
1) Tuesday - Saturday, 12:00pm - 8:30 pm
2) Tuesday - Saturday, 8:00pm - 4:30am

Responsibilities:

• Perform sectioning of tissue using a microtome and mounting on glass slides
• Perform routine staining of tissue sections with automated and/or manual staining techniques
• Perform automated and/or manual coverslipping of slides
• Generate digital slide images for pathologist examination
• Perform manual and automated macrodissection
• Operate and perform instrument maintenance
• Perform histology lab functions while following laboratory safety and quality policies
• Comply with standard laboratory operating policies and procedures
• Use of good documentation practices to record specimen data manually or in Laboratory Information Management Systems
• Help meet TAT goals while maintaining high-quality productivity
• Maintain clean and organized work areas within the laboratory
• Report problems to the department supervisor/manager to ensure timely resolution
  
  

Requirements:

• Associate's degree in chemical/physical/biological science or completion of a NAACLS-accredited Histotechnology program; Bachelor’s degree in a laboratory science curriculum preferred
• Minimum of 3+ years experience working in a high-volume histology laboratory performing microtomy of various tissue types, H&E staining, and tissue embedding
• HT or HTL certification from ASCP required
• Experience working in IHC and digital imaging, tissue/tumor identification, and proficiency in reading pathology reports, a plus
• Excellent attention to detail, organization, and time management skills
• Ability to communicate effectively with excellent interpersonal skills
• Physical demands include stooping, turning, bending, squatting, kneeling, and the ability to lift up to 25 lbs.

The hiring range for this position is $40.00 to $50.00 per hour, which may factor in various geographic regions. This shift is eligible for a shift differential pay bonus. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) 

#LI-KK1 #LI-Onsite

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Summary:

A CLS Supervisor performs and reports on clinical laboratory testing that aids physicians in diagnosing and treating patients. A key part of the role is supervising team members and ensuring that all laboratory procedures are followed for specimen handling, next-generation sequencing (NGS) processes, test analyses, and the accurate maintenance of patient records.

In our lab, we foster a positive, friendly, and team-based environment. We all pitch in to achieve our common goals and support each other. You'll work in a dynamic atmosphere, gaining hands-on experience at multiple benches, including extractions, library preparation, and sequencing. You'll also partner with our lab assistants to coordinate pre-analytical and post-analytical tasks.

Available Shifts:

• Sun - Thu, 10:00pm - 6:30am

Responsibilities: 

• Perform and report clinical laboratory testing on patient samples to aid physicians diagnose and treat patients. This includes the following areas:
• Extractions
• Library Preparation
• Enrichments
• Sequencing
• Handle and process all patient specimens according to laboratory procedures, ensuring accurate and timely record-keeping and reporting of results.
• Select, implement, and evaluate quality control materials for statistical process control of laboratory assays.
• Troubleshoot assays and equipment when quality control materials fail to perform as expected.
• Document all corrective actions taken when test systems deviate from established performance specifications.
• Assist in audits by regulatory bodies like CAP and external customers.
• Participate in activities that support the laboratory's necessary licensure, including quality management and on-site inspections.
• Identify and correct problems that may negatively affect test performance or result reporting. If a problem cannot be immediately corrected, notify a supervisor, clinical consultant, or director.
• Train other CLS and lab personnel on laboratory methods.
• Monitor the activities of non-licensed staff.
• Provide guidance to team members on troubleshooting and deviation investigations.
• Assist in assay development activities.
• Demonstrate strong analytical skills and independent critical thinking.
• Apply technical and functional knowledge to help the team meet its goals.
• Work independently to identify and resolve complex, open-ended problems.

Requirements:

• Education: Bachelor's degree, preferably in sciences or related discipline.
• Licensure: Valid California Clinical Laboratory Scientist (CLS) or Clinical Genetic Molecular Biologist Scientist (CGMBS) license.
• Experience: At least four years of CLS experience in a clinical laboratory environment. Minimum 1 year experience in a Lead role is required.
• Preferred Skills: Experience with manual DNA/RNA extractions, manual library preparation, and automated liquid handlers.

The hiring range for this position is $72.10 to $81.70 per hour plus applicable shift differential. The offer will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

#LI-KK1 #LI-Onsite

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Shifts Available:

• Friday - Tuesday: 10pm - 6:30am (3rd Shift)
• Tuesday - Saturday: 10pm - 6:30am (3rd Shift)

Training hours may be different from your shift schedule. 

Responsibilities:

• Perform nucleic acid extraction from various sample types in a Biosafety Level 2 laboratory (e.g., FFPE, blood, plasma, and more)
• Quantify extracted materials by following QC protocols
• Prepare extracted materials for library prep using automated and manual procedures. 
• Record sample processing workflows in real-time through a Laboratory Information Management System (LIMS)
• Maintain robotic liquid handlers and other instruments for optimal performance 
• Assists in data transfer and basic QC evaluation of data 
• Perform troubleshooting and system evaluations when necessary, in communication with the automation support team, laboratory supervisor, and/or third-party technical support teams 
• Escalates issues to a supervisor when problems arise with sample processing 
• Maintain appropriate supplies and equipment to maximize department efficiency and meet established budgetary and quality goals 
• Support and ensure compliance with the laboratory’s quality control procedures and policies 
• Document all corrective actions taken when test systems deviate from the laboratory’s established performance specifications 
• Demonstrate knowledge of laboratory safety protocols 
• Demonstrate commitment to quality and continuous improvement 
• Use effective two-way communication and participate in general laboratory meetings 
• Perform other duties as assigned, including performing workflows outside of extractions

Requirements:

• BA/BS in a biological discipline 
• 0-2 years of relevant laboratory experience 
• Familiarity with Hamilton, or other robotic liquid handlers, is desired 
• Familiarity with LIMS or sample management tracking systems is desired 
• Familiarity with Quality control of samples and quantification devices (e.g., TapeStation, Qubit, qPCR) 
• Flexible and adaptive in a frequently changing environment 
• Strong communication skills, ensuring effective communication when issues arise.
• Strong organizational skills and attention to detail 
• Ability to analyze and solve basic problems 
• Ability to work as part of a team in a highly collaborative environment 
• Ability to work independently with minimal supervision 
• Desire to learn new skills and grow his/her knowledge of next-generation sequencing technologies 
• Strong desire to work in a demanding, high-energy, hands-on environment
  
  

The hiring range for this position is $27.50 to $34.60 per hour, which may factor in various geographic regions. This shift is eligible for an additional shift premium. The base pay actually offered will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contacts you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis is an Equal Opportunity Employer/Minorities/Females/Veterans/Disabilities. Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) 

#LI-KK1 #LI-Onsite

At Personalis, we are transforming the active management of cancer through breakthrough personalized testing. We aim to drive a new paradigm for cancer management, guiding care from biopsy through the life of the patient. Our highly sensitive assays combine tumor-and-normal profiling with proprietary algorithms to deliver advanced insights even as cancer evolves over time. Our products are designed to detect minimal residual disease (MRD) and recurrence at the earliest timepoints, enable selection of targeted therapies based on ultra-comprehensive genomic profiling, and enhance biomarker strategy for drug development. Personalis is based in Fremont, California.

Shift(s) Available:

• Sunday - Thursday: 10pm - 6:30am (3rd Shift)
• Tuesday - Saturday: 2pm - 10:30pm (PM Shift)

Training hours may be different from your shift schedule. The PM and 3rd shift would be eligible for an additional shift premium.

Summary:

A CLS Supervisor performs and reports on clinical laboratory testing that aids physicians in diagnosing and treating patients. A key part of the role is supervising team members and ensuring that all laboratory procedures are followed for specimen handling, next-generation sequencing (NGS) processes, test analyses, and the accurate maintenance of patient records.

In our lab, we foster a positive, friendly, and team-based environment. We all pitch in to achieve our common goals and support each other. You'll work in a dynamic atmosphere, gaining hands-on experience at multiple benches, including extractions, library preparation, and sequencing. You'll also partner with our lab assistants to coordinate pre-analytical and post-analytical tasks.

Responsibilities: 

• Perform and report clinical laboratory testing on patient samples to aid physicians diagnose and treat patients. This includes the following areas:
• Extractions
• Library Preparation
• Enrichments
• Sequencing
• Handle and process all patient specimens according to laboratory procedures, ensuring accurate and timely record-keeping and reporting of results.
• Select, implement, and evaluate quality control materials for statistical process control of laboratory assays.
• Troubleshoot assays and equipment when quality control materials fail to perform as expected.
• Document all corrective actions taken when test systems deviate from established performance specifications.
• Assist in audits by regulatory bodies like CAP and external customers.
• Participate in activities that support the laboratory's necessary licensure, including quality management and on-site inspections.
• Identify and correct problems that may negatively affect test performance or result reporting. If a problem cannot be immediately corrected, notify a supervisor, clinical consultant, or director.
• Train other CLS and lab personnel on laboratory methods.
• Monitor the activities of non-licensed staff.
• Provide guidance to team members on troubleshooting and deviation investigations.
• Assist in assay development activities.
• Demonstrate strong analytical skills and independent critical thinking.
• Apply technical and functional knowledge to help the team meet its goals.
• Work independently to identify and resolve complex, open-ended problems.

Requirements:

• Education: Bachelor's degree, preferably in sciences or related discipline.
• Licensure: Valid California Clinical Laboratory Scientist (CLS) or Clinical Genetic Molecular Biologist Scientist (CGMBS) license.
• Experience: At least four years of CLS experience in a clinical laboratory environment. Minimum 1 year experience in a Lead role is required.
• Preferred Skills: Experience with manual DNA/RNA extractions, manual library preparation, and automated liquid handlers.

The hiring range for this position is $72.10 to $81.70 per hour plus applicable shift differential. The offer will take into account internal equity and also may vary depending on the candidate’s geographic region, job-related knowledge, skills, and experience among other factors. Our full-time regular positions also include an annual performance-based bonus (or a sales incentive plan) and long-term incentive units (equity) provided as part of our compensation package, in addition to a full range of medical, financial, and/or other benefits, dependent on the level and position offered.

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know, if/when they contact you.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.)

#LI-KK1 #LI-Onsite

Personalis is an equal opportunity employer and is committed to the full inclusion of all individuals. As part of this commitment, Personalis will ensure that persons with disabilities are provided with reasonable accommodations. If you need an accommodation to participate in the job application or interview process, to perform essential job functions, and/or to receive other benefits and privileges of employment, please let your recruiter know.

Protecting Our Candidates: At Personalis, we value your security. Please note that all official correspondence from our team will come exclusively from @personalis.com email addresses. We will never ask for personal financial information or conduct interviews over text or chat platforms. If you receive a suspicious request, it is likely a scam. We are committed to a safe recruitment experience and actively work with authorities to investigate and prosecute cyber crimes targeting our community.

Personalis offers a competitive compensation package and benefits including medical, dental, vision, 401(k) match, ESPP, tuition reimbursement, sick/vacation time, commuter benefits/ EV charging stations, onsite gym, and wellness benefits. (For US only, benefits in other countries may vary.) 

#LI-KK1 #LI-Onsite