“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

National Sales Director

The National Sales Director (NSD) will serve as a senior field leader responsible for building and leading a high-performing commercial organization across a large U.S. geography in support of Mineralys’ first product launch. This role will lead a team of Regional Sales Directors and their sales teams, ensuring flawless launch execution, strong customer engagement, and achievement of business objectives.

The NSD will act as a strategic business partner to the VP of Sales and cross-functional leadership team, helping shape launch strategy, field execution plans, talent development, and organizational culture. This role requires a seasoned leader with deep launch experience, strong business acumen, and the ability to scale teams in a fast-paced biotech environment.

Key Responsibilities

Commercial Strategy / Launch Leadership

• Lead launch planning and execution across assigned area to ensure achievement of sales, market access, and market share goals
• Translate national commercial strategy into actionable area business plans and execution priorities
• Monitor business performance, identify risks/opportunities, and implement corrective actions quickly
• Drive launch excellence, customer engagement, and field execution consistency
• Provide ongoing market insights and competitive intelligence to commercial leadership

Field Leadership / Team Development

• Recruit, onboard, and develop Regional Sales Directors (RSD) and support their hiring of top field talent
• Lead, coach, and develop a team of approximately 15 RSDs and indirect oversight of 50–100+ field representatives
• Establish a high-performance culture focused on accountability, collaboration, and execution
• Conduct regular field coaching, business reviews, and talent assessments
• Build leadership bench strength and succession plans

Cross-Functional Partnership

• Partner closely with Market Access, Marketing, Medical Affairs, Training, Operations, Compliance, and HR to support launch readiness and sustained execution
• Collaborate with Area Sales Director peers and VP of Sales to ensure national alignment and share best practices
• Support national sales meetings, launch planning sessions, and leadership forums
• Partner with Market Access on payer, IDN, and organized customer strategy as needed

Business Operations / Compliance

• Manage area budget, resources, and deployment plans
• Ensure forecasting accuracy, CRM utilization, and performance reporting
• Drive compliance with all company policies, industry regulations, and legal requirements
• Promote Mineralys’ values of collaboration, integrity, quality, trust, and urgency

Qualifications

• Bachelor’s degree required; advanced degree preferred
• 12+ years of pharmaceutical / biotech sales experience
• 5+ years of field sales leadership experience, including leadership of leaders
• Prior launch experience required; first-launch / emerging biotech experience strongly preferred
• Demonstrated success leading specialty sales organizations and exceeding performance goals
• Experience in cardiovascular, nephrology, hypertension, or related specialty markets strongly preferred
• Strong coaching, talent assessment, and leadership development skills
• Proven ability to work cross-functionally and influence without authority
• Strong business planning, analytical, and problem-solving skills
• Ability to travel extensively within area and nationally as needed

Leadership Profile

• A builder who thrives in creating infrastructure and scaling teams
• A visible, hands-on leader who drives accountability and results
• Agile and comfortable with ambiguity in a launch environment
• Highly collaborative and able to influence across the organization
• Passionate about developing talent and building culture

Travel

• This position requires up to 60% travel. Frequently travel is outside the local area and overnight.

These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $260,000 - $285,000

#LI-REMOTE

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

Manager, Marketing Capabilities & Operations

As we prepare for our first commercial launch, we are seeking an experienced marketing operations professional who is energized by the opportunity to build from the ground up and establish foundational process capabilities.

Reporting to the Director of Marketing Capabilities & Operations, the Manager will play a critical role in enabling Mineralys Therapeutics’ first commercial launch. The Manager will help lead the day-day operational activities of the PRC (Promotional Review Committee) process to support the successful launch of lorundrostat.

This position helps manage material workflows, ensures that materials move efficiently through concept review, internal routing, regulatory/legal/medical review, and final deployment while maintaining compliance with process standards

The Manager will work cross‑functionally with internal and external stakeholders to ensure high quality submissions and timely review of materials in a fast‑moving, entrepreneurial launch environment.

Key Responsibilities

• Manage routing and tracking of promotional materials through the review process (from submission to final approval).
• Align on reviewer expectations, timing, prioritization, and cross functional readiness.
• Serve as the meeting facilitator for the material review meetings, setting agendas and managing post-review outcomes (such as: resubmissions and approval documentation).
• Ensure requested changes are captured and material sponsors and agency partners take responsibility to ensure changes are pulled through on materials.
• Develop strong expertise in submission platforms (e.g., Veeva), and approval workflows.
• Works with the marketing operations leader to guide and train promotional material sponsors and agencies on submitting compliant materials, review timelines, and planning approvals.
• Works with the team and senior management when there is agreement to escalate materials for additional discussions by following established escalation procedures.

Marketing Production & Distribution 

• Collaborate with the marketing operations leader, material sponsors and agencies on final distribution requirements for print and digital materials.
• Partner with operations leader and Regulatory Reviewer to ensure workflows for 2253 submissions are in place and track submission status.
• Work closely with marketing and field sales to ensure materials are not distributed until final approval for distribution is granted following 2253 submission (if required).

Process Optimization 

• Partner with marketing operations leader (and other key stakeholders) to update workflows, SOPs, and quality controls for promotional review.

 Education and Experience

• 8+ years of pharmaceutical/biotech experience in marketing operations, medical/promotional review operations, or related commercial execution roles.
• Strong experience in the day-to-day management of PRC processes in regulated environments.
• Expertise in Veeva PromoMats and related review/workflow tools.
• Experience supporting first commercial launches strongly preferred.
• Bachelor’s degree required.
• Exceptional program and project management skills.
• Strong facilitator who can influence without authority.
• Detail‑driven, organized, and able to manage multiple complex workflows.
• Clear, concise communicator who thrives in a fast‑moving, high‑expectation environment.

Travel 

• This position requires up to 20% travel.  Frequently travel is outside the local area and overnight. Some of the travel may be international. 

These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $112,000 - $130,000

#LI-REMOTE

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

Senior Director, Sales Training & Effectiveness

Reporting to the VP of Marketing, the Senior Director, Sales Training & Effectiveness will lead the strategy and execution of sales training and field effectiveness initiatives to ensure launch readiness and commercial performance. This role is responsible for shaping the field capability strategy—translating brand strategy into clear training priorities, defining field excellence standards, and enabling effective sales execution through onboarding, ongoing development, and performance optimization.

This role requires both strategic leadership and hands-on execution. The ideal candidate will be a self-starter with deep experience in sales training and commercial effectiveness, including launch planning, field onboarding, capability development, performance measurement, and cross‑functional leadership. Mineralys is seeking individuals who thrive in an entrepreneurial environment and are motivated to build exceptional field capabilities from day one.

Previous product launch leadership and experience in cardiovascular and/or chronic care markets is strongly preferred.

Key Responsibilities

Sales Training Strategy & Governance

• Develop and own the end-to-end sales training and effectiveness strategy aligned to launch milestones and commercial objectives
• Establish a clear field capability model spanning disease education, product knowledge, selling skills, account management, and compliant execution
• Serve as the single point of accountability for field readiness and training excellence

Launch & Onboarding Excellence

• Lead initial sales force onboarding and certification, ensuring readiness at launch
• Design and execute launch training, POA meetings, workshops, and reinforcement plans
• Partner closely with Marketing, Medical Affairs, and Compliance to ensure aligned, accurate, and approved content

Ongoing Capability Development

• Build and deliver ongoing training curricula to support continuous performance improvement
• Develop leadership and coaching capabilities for first-line and second-line field leaders
• Leverage blended learning approaches (live, virtual, digital, field-based)

Sales Effectiveness & Performance Optimization

• Drive field force effectiveness by ensuring training and field insights support commercial strategy and execution
• Partner with Sales Leadership and Commercial Analytics to identify skill gaps, performance trends, and execution opportunities
• Establish performance indicators to assess and optimize launch performance and training/field effectiveness.
• Translate field insights into targeted training and enablement interventions

Cross-Functional Leadership

• Act as a strategic liaison across Sales, Marketing, Medical Affairs, Market Access, and Compliance
• Ensure consistent messaging, execution standards, and compliance across all customer-facing roles
• Onboard and manage external training vendors and learning partners

Qualifications

• MBA or bachelor’s degree
• 10+ years of pharmaceutical or biotech industry commercial experience
• Cardiovascular and/or chronic care experience is highly preferred.
• Demonstrated ability to operate strategically while driving flawless execution
• Experience navigating MLR/promotional review processes and a working understanding of pharmaceutical compliance requirements for field-facing content
• Familiarity with learning technologies and CRM-enabled training tools (e.g., Veeva, LMS platforms)
• A builder mindset with high personal accountability, resourcefulness, and a collaborative spirit
• Experience effectively leading cross-functional teams and agency partners.
• Proven ability to lead through ambiguity and define direction
• Excellent communication and presentation skills.

Travel

• This position requires up to 10% travel. Frequently travel is outside the local area and overnight.

This position is eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $215,000 - $250,000

#LI-Remote

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

Marketing Coordinator

Reporting to the VP, Marketing, this role is a hybrid position that combines senior-level administrative partnership with hands-on marketing coordination and team operations leadership. The Marketing Coordinator will provide day-to-day administrative support to the VP of Marketing while also serving as a key contributor to the execution of Mineralys’ marketing initiatives as the organization prepares for launch. 

Operating in a fast-paced, entrepreneurial biopharmaceutical environment, this role requires someone who is highly organized, proactive, and comfortable shifting between strategic support, operational execution, and creative coordination. The ideal candidate is a self-starter who brings strong administrative fundamentals and an interest in driving coordination, communication, and execution across the broader Marketing and cross-functional teams. 

This position will partner closely with cross-functional stakeholders including Sales, Medical Affairs, Market Access, Finance, Legal, and external agencies and vendors. 

Principal Responsibilities 

Administrative Support to the VP of Marketing & Department 

• Provide high-level administrative support to the VP of Marketing, including meeting coordination, travel arrangements, and expense reporting.
• Act as a trusted administrative partner, managing priorities, anticipating needs, and ensuring the VP of Marketing is prepared for internal and external meetings.
• Coordinate meeting logistics, agendas, materials, and follow-ups for leadership, agency, and cross-functional marketing meetings.
• Support development and refinement of presentations, pre-reads, and executive-ready materials.
• Coordinate CDAs, consulting agreements, SOWs, POs in partnership with Legal and Finance.
• Handle confidential and sensitive information with professionalism, discretion, and sound judgment.

Marketing Coordination & Execution 

• Serve as a marketing coordinator supporting the planning and execution of marketing initiatives and key deliverables.
• Partner with Finance to support brand budget tracking, invoice processing, and spend visibility. 
• Assist with the organization and maintenance of marketing assets, templates, and files (e.g., SharePoint or other content management tools).
• Coordinate with external agencies, vendors, and consultants to support marketing programs and initiatives.
• Support logistics and execution for commercial meetings, internal communications, and cross-functional updates.
• Help plan and execute engaging, well-organized Marketing and cross-functional team update meetings that build alignment, momentum, and connection.

Systems, Process & Team Support 

• Serve as a key administrative and operational user for Marketing systems and tools (e.g., SharePoint, project tracking tools, or content platforms as applicable).
• Support onboarding and training logistics for new Marketing team members.
• Help establish and maintain organized, scalable processes to support a growing Marketing organization.
• Act as a flexible resource across Marketing projects as priorities evolve.

Education and Experience

• 10+ years of experience in an administrative support, marketing coordination, or hybrid role; experience in life sciences, biotech, or a regulated environment is preferred.
• Demonstrated experience supporting senior leaders with complex scheduling and administrative needs.
• Interest in marketing and commercial coordination, and execution; prior exposure to marketing, communications, or commercial teams is a plus.
• Exceptional organizational skills with the ability to manage multiple priorities in a dynamic, fast-paced environment.
• Proactive, anticipatory mindset and ability to follow through with urgency and accountability.
• High energy, positive attitude, and a true roll-up-your-sleeves mentality.
• Ability to build trusted working relationships across all levels of the organization.
• Excellent judgment, discretion, and professionalism when handling confidential information.

Travel

• This position requires up to 20% travel.  Frequently travel is outside the local area and overnight. Some of the travel may be international.

Position eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $80,000 - $95,000

#LI-Remote

“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone.  Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor.  Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

As we prepare for our first commercial launch, we are seeking an experienced marketing leader who is energized by the opportunity to build from the ground up, establish foundational capabilities, and shape the promotional medical education strategy for a best‑in‑class launch.

Reporting to the VP of Marketing, the Director, HCP Marketing & Thought Leader Engagement will serve as the strategic and operational leader responsible for defining and executing Mineralys’ promotional medical education and thought leader strategy across medical congresses, KOL engagement, advisory boards, speaker programs, and promotional medical education. This person will serve as the commercial lead for LCM planning and work cross-functionally to provide strategic insight into unmet needs, real world gaps, and future areas of opportunity.

This role plays a critical launch role establishing Mineralys within the cardio renal metabolic (CRM) and hypertension communities. We are seeking a leader with deep pharmaceutical marketing expertise, ideally with chronic care and launch experience, to ensure all engagement activities support pre-launch efforts, inform brand strategy, and accelerate launch readiness.

The ideal candidate can operate strategically while executing with precision in a lean, fast‑moving, launch‑focused environment.

Key Responsibilities

• Developed and launched a comprehensive Promotional Medical Education platform encompassing a Congress Strategy, Speakers Bureau, National Broadcasts, and Third-Party Educational Content for both pre-launch unbranded and branded initiatives
• Lead strategy, design, and execution of national and regional advisory boards, aligning to evidence gaps and shaping scientific narrative.
• Develop a structured KOL engagement roadmap across pre‑ and post‑approval phases and foster relationships with national and regional thought leaders in hypertension and CVRM care
• Build Mineralys’ first speaker bureau including recruitment, evaluation, training, content development, and performance monitoring
• Develop and execute industry leading non-personal promotional medical educational programs
• Lead commercial efforts to provide strategic insight into unmet needs, real‑world gaps, and future opportunity areas into clinical development and investment decisions to ensure commercially competitive clinical profiles for LCM planning
• Work cross‑functionally to pressure‑test potential LCM scenarios and support evidence‑generation prioritization.
• Collaborate cross-functionally to build processes and ensure compliance in HCP contracting, fair‑market‑value adherence, Sunshine Act reporting, promotional content review, and program execution

Travel

 Education and Experience

 These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range:  $200,000 - $220,000

#LI-REMOTE