BillionToOne is seeking a Product Management Intern (Clinical) to support objectives in the oncology product portfolio (Northstar Select and Response). This person will work to define user requirements and pain points, develop a product roadmap, and execute a successful launch. The ideal candidate will be independent, metrics-driven, and comfortable interfacing with a diverse group of stakeholders.

Responsibilities

• Product strategy and planning: Collaborate cross-functionally to develop product strategy, define success criteria, and create roadmaps.
• Data analysis: Conduct data analysis to inform a product roadmap and provide strategic recommendations.
• Project management and execution: Deliver quality products through scope definition, agile project management, and effective stakeholder communication.
• Communication and documentation: Create detailed specifications for the project team and develop clear business and technical documentation to support project efforts. Foster relationships across multiple teams, manage expectations, and communicate upwards.
• Collaboration with internal stakeholders: Closely collaborate with internal teams (including Client Services, Sales, Genetic Counseling, Software Engineering, and Lab personnel) to understand user requirements and facilitate project communication.

Requirements

• Currently pursuing a Master’s degree, ideally in business administration, biological sciences, engineering, or other related field
• Experience in biotechnology or healthcare industry preferred
• Command of product principles, techniques, and best practices
• Solid analytical skills to interpret internal data and leverage external data sources 
• Comfortable working with highly technical teams, including software engineers, bioinformaticians, and data scientists
• Excellent communication (verbal and written) and interpersonal skills, with the ability to collaborate effectively across teams and communicate complex concepts to stakeholders
• Ability to adapt to an ambiguous and evolving internal and external environment

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, and (2) the opportunity for professional growth.

For this position, the base pay rate is $25 per hour.

BillionToOne is seeking a Clinical Laboratory General Supervisor (GS) to support our Oncology product, Northstar, in a high-complexity CLIA laboratory environment. This role provides general supervision of personnel and daily laboratory operations, ensuring regulatory compliance, quality, and operational excellence across end-to-end cancer blood sample processing.

This is a hands-on leadership role in a fast-growing, high-throughput molecular diagnostics lab. The General Supervisor will serve as a key operational leader and first point of escalation for CLS and CLA, partnering closely with the Technical Supervisor, Laboratory Director, and Quality team.

This is an onsite position supporting the Monday–Friday Mid Shift (11:30 AM – 8:00 PM), with a planned transition to a PM shift (3:00 PM – 11:30 PM) later this year.

Responsibilities:

• General Supervision & Leadership
  • Serve as a designated CLIA General Supervisor for high-complexity testing in accordance with 42 CFR Part 493 and CAP accreditation standards
  • Provide day-to-day supervision of laboratory personnel, including CLSs and CLAs, during the pre-analytic, analytic, and post-analytic phases of testing
  • Act as the primary escalation point for technical, operational, and personnel issues during assigned shifts
  • Oversee staffing, scheduling, shift handoffs, and workload distribution to ensure operational continuity
• Laboratory Operations & Testing
  • Perform and oversee high-complexity molecular oncology assays, supporting diagnostic testing for patient care
  • Ensure proper instrument operation, calibration, maintenance, and troubleshooting
  • Review, interpret, and verify test results and quality control data
  • Identify, investigate, and resolve deviations that may impact test performance or result integrity
• Quality & Compliance
  • Ensure compliance with CLIA, CAP, state, and local regulatory requirements
  • Perform, review, and document quality control, corrective actions, and preventive maintenance
  • Participate in inspection readiness, audits, and regulatory responses
  • Lead or support SOP development, review, and biennial updates
• Training & Continuous Improvement
  • Lead training, onboarding, and competency assessments for new and existing laboratory staff
  • Provide hands-on and theoretical training for new assays, processes, and instrumentation
  • Support process improvement initiatives, including assay validation, tech transfer, and troubleshooting
  • Partner cross-functionally with Quality, R&D, and Operations to drive continuous improvement

Qualifications:

• Active California Clinical Laboratory Scientist (CLS) license (or CGMBS/generalist license) meeting CLIA requirements for high-complexity testing
• Bachelor’s degree in chemical, biological, physical, clinical laboratory science, or a related field
• Minimum 4 years of clinical laboratory experience, including molecular and/or high-complexity testing
• Meets CLIA General Supervisor qualifications under 42 CFR 493.1461, including appropriate education, training, and experience
• Demonstrated hands-on experience with molecular biology techniques (e.g., DNA extraction, PCR, automated liquid handlers)
• Strong working knowledge of LIMS, quality systems, and laboratory documentation
• Proficiency with Google Docs, Excel, Word, and basic statistical analysis
• Excellent attention to detail, organizational skills, and ability to perform under time-sensitive conditions
• Strong written and verbal communication skills and a collaborative leadership style

Nice-To-Haves:

• Prior experience serving as a CLIA General Supervisor
• Startup or high-growth laboratory experience
• Background in medical genetics or oncology diagnostics
• Experience working with cell-free DNA (cfDNA) or next-generation sequencing workflows

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $217,805 per year, including a base pay range of $158,401 - $179,521 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are looking for an interdisciplinary Research Associate to perform experiments and assays under the guidance of Senior Scientists. The Research Associate is an on-site position in our Menlo Park, CA office.

Responsibilities:

• Perform experiments and assays under the guidance of Senior Scientists
• Learn analytical and computational methodologies and analyze the results under the guidance of Senior Scientists
• Assist Senior Scientists in assay development
• Keep accurate and meticulous records of experimental details and results
• Prepare biological samples and reagents to accelerate the R&D process
• Manage, organize, and support lab operations

Requirements:

• BS or MS in Molecular and Cell Biology, Microbiology, Biophysics, Biochemistry, or related field
• 1-2 years of research experience (either during BS/MS or afterwards)
• Previous experience with standard molecular biology techniques (in particular, extensive experience with PCR, electrophoresis, DNA purifications)
• An ability to quickly learn mathematical, analytical, and experimental concepts
• High mathematical and statistical aptitude (e.g., you find GRE math section to be extremely easy)
• Great attention to detail

Nice-To-Haves:

• Start-up experience
• Knowledge of medical genetics
• Experience in a cell-free DNA setting
• Experience with next-generation sequencing library preparation
• Experience with computational analysis in R, Python, or other programming language

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of up to $102,929 per year, including a base pay range of $73,920 - $84,480 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are seeking a dynamic and experienced Director of IT to oversee and manage our Dev Ops and IT strategy. The ideal candidate will have a strong background in networking, infrastructure management, AWS cloud services and cybersecurity. This role will be pivotal in maintaining and enhancing our IT systems to support our business operations and growth. The Director of IT is a hybrid position (onsite 2-3 days per week) and reports to the VP of IT/IS.

Key Responsibilities:

• IT Leadership and Strategy:
• Develop and implement IT strategies aligned with the company's scaling goals.
• Lead and manage the IT team, fostering a culture of excellence and continuous improvement.
• Oversee the design, implementation, and maintenance of the company's cloud infrastructure and set it up as a service for the organizations.
• Networking and Infrastructure:
• Ensure the reliability, security, and efficiency of our networking systems.
• Manage network configuration, performance monitoring, and troubleshooting.
• Oversee the setup, configuration, and maintenance of servers, storage, and other infrastructure components.
• Implement and manage disaster recovery and business continuity plans.
• AWS Cloud Management:
• Design and manage AWS cloud infrastructure, ensuring scalability, performance, and security.
• Oversee the strategy, deployment and management of AWS services, including EC2, S3, RDS, and VPC.
• Optimize cloud resources for cost-efficiency and performance.
• Implement and manage cloud security policies and procedures.
• Security and Compliance:
• Ensure IT security measures are in place and regularly updated to protect against data breaches and cyber threats.
• Ensure compliance with industry standards and regulations, including HIPAA, SOC 2 and other relevant guidelines.
• Conduct regular security audits and vulnerability assessments.
• Project Management:
• Lead IT projects from conception through completion, ensuring they are delivered on time and within budget.
• Collaborate with cross-functional teams to support IT needs for various initiatives.
• Manage vendor relationships and negotiate contracts for IT services and products.
• Support and Maintenance:
• Oversee the IT support function to ensure timely resolution of technical issues and maintain a high standard of service satisfaction.
• Maintain an inventory of IT assets and manage lifecycle processes.
• Implement IT policies and procedures, ensuring staff adherence.

Qualifications:

• Bachelor's degree in Computer Science, Information Technology, or a related field. A Master's degree is a plus.
• Minimum of 8 years of experience in IT, with at least 3 years in a managerial or leadership role.
• Extensive experience with networking technologies, infrastructure management, and AWS cloud services.
• Proficiency in networking technologies (LAN, WAN, VPN, firewall, etc.).
• Strong knowledge of server and storage systems, virtualization, and data centers.
• Expertise in AWS services, architecture, and best practices.
• Experience with IT security protocols and compliance standards, SOC 2 preferred.
• Excellent leadership and team management skills.
• Strong problem-solving and decision-making abilities.
• Effective communication and interpersonal skills.
• Ability to manage multiple projects and priorities in a fast-paced environment.

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, (2) the opportunity for professional growth, and (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave etc.).

For this position, we offer a total compensation package of $421,554 per year, including a base pay range of $214,369 - $267,962 per year.

We are seeking an entrepreneurial and highly strategic leader for the Head of Strategic Pharma Partnerships, Oncology role. This position is pivotal in driving BillionToOne’s growth by forging impactful partnerships with pharmaceutical companies and exploring innovative product opportunities in the precision diagnostics and oncology space. The role combines business development expertise with product exploration to identify and validate new use cases for our oncology liquid biopsy solutions.

The ideal candidate will have a strong understanding of both the technical and commercial aspects of precision diagnostics, excel in customer engagement, and thrive in a fast-paced, dynamic environment. This role reports to the Chief Product Officer.

Responsibilities:

• Actively identify and engage pharmaceutical companies to build strategic partnerships for BillionToOne’s oncology product lines.
• Negotiate and close partnership agreements that drive business growth and align with our strategic goals.
• Represent BillionToOne at industry conferences and events to establish and strengthen relationships with key stakeholders.
• Collaborate with internal teams (R&D, Clinical, and AI) to identify new product opportunities and validate their potential with pharmaceutical partners.
• Act as the primary advocate for pharmaceutical customers, deeply understanding their needs and translating them into actionable product insights.
• Partner with internal teams to co-develop solutions that address unmet needs in oncology diagnostics.
• Work with Clinical and R&D teams to align on technical feasibility and ensure smooth execution of partnership projects.
• Collaborate with legal and finance teams to structure and finalize deal terms.
• Maintain a feedback loop with internal stakeholders to iterate on product concepts and improve partnership success rates.

Qualifications:

• 10+ years of experience in business development, product partnerships, or a related role in precision diagnostics or life sciences.
• Proven track record of closing complex deals with pharmaceutical companies.
• Strong understanding of oncology diagnostics and liquid biopsy technologies.
• Ability to bridge the gap between technical teams and business stakeholders, translating scientific concepts into commercial opportunities.
• Exceptional communication and relationship-building skills.
• Entrepreneurial mindset with a passion for product innovation and customer success.
• Strategic thinker with the ability to execute effectively in a dynamic, fast-paced environment.
• Willingness to travel (up to 25%) to engage partners and attend key industry events.

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $397,170 to $400,402 per year, including a base pay range of $242,881 to $264,002 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are looking for a Reagent Manufacturing Associate II, Oncology to join our growing reagent manufacturing team in support of clinical patient testing in our high throughput CLIA lab. The Reagent Manufacturing Associate II will be responsible for assisting with the manufacturing, assembly, and qualification of reagents in support of clinical laboratory operations at BillionToOne. The selected candidate will also be responsible for assisting in the troubleshooting of reagent manufacturing activities, management of sufficient reagent inventory, and operation of high-throughput automated equipment to support operations. . This position requires an individual with excellent attention to detail, effective written and verbal communication skills, the ability to multitask, and the ability to work both independently and as part of a highly collaborative team environment. The role is a full-time onsite position in Menlo Park, CA and reports to Senior Process Engineer II, Oncology. 

Shift Hours: Monday - Friday, 9am - 5pm

Responsibilities:

• Manufacture medium and high complexity reagents in a molecular manufacturing lab according to established SOPs.
• Operation of robotic laboratory equipment and traditional lab equipment (micropipettes, liquid handlers, thermal cyclers, centrifuges, sealers, sonicator, etc.)
• Use of traditional molecular biology processes and techniques (small volume pipetting, plating, quantitation, visual inspection)
• Maintaining thorough, accurate and detailed documentation of all work produced, including deviations
• Inventory management
• Collaborate with Research and Development for the scale-up and implementation of new reagent formulations.
• Participate in reagent troubleshooting and quality monitoring
• Lab maintenance such as labware cleaning and equipment maintenance as needed
• Daily completion of assigned tasks to keep manufacturing on track
• Reagent manufacturing will primarily be operating out of Menlo Park but may require some flexibility to work out of the Union City location

Requirements:

• Bachelor’s degree or equivalent degree in biology, chemistry, or clinical related sciences
• At least one year of experience with molecular biology techniques in a research or clinical laboratory
• Excellent attention to detail
• Effective written and verbal communication skills
• The ability to multitask and work independently
• Patience and flexibility
• Previous clinical laboratory experience is preferred

Nice-to-Haves:

• Start-up experience
• Experience in a cell-free DNA setting
• Experience developing training programs and performing knowledge transfer.
• Strong communication skills (verbal and written).
• Ability to effectively work in a team environment and build strong working relationships.
• High degree of initiative and self-motivation.

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Free UNITY Complete NIPT testing for employees & spouses
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $105,218 per year, including a base pay range of $80,388 - $91,107 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

BillionToOne is seeking a Product Management Intern (Software Engineering) to to support objectives in the oncology product portfolio (Northstar Select and Response). This person will work to define user requirements and pain points, develop a product roadmap, and execute a successful launch. The ideal candidate will be independent, metrics-driven, and comfortable interfacing with a diverse group of stakeholders.

Responsibilities

• Product strategy and planning: Collaborate cross-functionally to develop product strategy, define success criteria, and create roadmaps.
• Data analysis: Conduct data analysis to inform a product roadmap and provide strategic recommendations.
• Project management and execution: Deliver quality products through scope definition, agile project management, and effective stakeholder communication.
• Communication and documentation: Create detailed specifications for the project team and develop clear business and technical documentation to support project efforts. Foster relationships across multiple teams, manage expectations, and communicate upwards.
• Collaboration with internal stakeholders: Closely collaborate with internal teams (including Client Services, Sales, Genetic Counseling, Software Engineering, and Lab personnel) to understand user requirements and facilitate project communication.

Requirements

• Currently pursuing a Master’s degree, ideally in business administration, biological sciences, engineering, or other related field
• Experience in biotechnology or healthcare industry preferred
• Command of product principles, techniques, and best practices
• Solid analytical skills to interpret internal data and leverage external data sources 
• Comfortable working with highly technical teams, including software engineers, bioinformaticians, and data scientists
• Excellent communication (verbal and written) and interpersonal skills, with the ability to collaborate effectively across teams and communicate complex concepts to stakeholders
• Ability to adapt to an ambiguous and evolving internal and external environment

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, and (2) the opportunity for professional growth.

For this position, the base pay rate is $25 per hour.

We are looking for a Bioinformatics Intern, Prenatal to join and support our Bioinformatics team in developing bioinformatics pipelines and analyzing next-generation DNA sequencing data. This position will focus on an analysis and/or development project with guidance from Bioinformatics team members. BTO is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. This internship will provide valuable mentorship from BI Associates and BI Senior Scientists, hands-on experience, and professional development opportunities. The Bioinformatics Intern is a full-time onsite position in our Menlo Park office for 10 weeks.

Responsibilities:

• Conduct a research and/or development project centered on one of our prenatal assays
• Improve next-generation sequencing analysis pipelines under the guidance of  Bioinformatics team members
• Communicate through presentations, written reports, and/or code review
• Collaborate with scientists and support new scientific insights

Requirements:

• Currently enrolled in a Bachelor's or Master's program in Bioinformatics, Biology, Computational Biology, Computer Science, Bioengineering, Physics, or other related fields
• Strong programming skills in Python and R 
• High mathematical and statistical aptitude
• Great attention to detail
• Curious about pursuing a career in Bioinformatics

Nice-To-Haves:

• Familiarity with MS Excel, bash, AWS, SQL, and git
• Research experience in bioinformatics, biology, or physical sciences
• Molecular biology (DNA purification, PCR, electrophoresis) or next-generation DNA sequencing laboratory experience

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, and (2) the opportunity for professional growth.

For this position, the base pay rate is $25 per hour.

We are currently looking for a high-performing Senior Software Engineer, Prenatal to join our dynamic software engineering team. Software engineers at BillionToOne work in highly collaborative and interdisciplinary teams of clinicians, computational biologists, and other engineers to robustly scale personalized genomic medicine to millions of patients. If you have experience performing in a full life-cycle development, love seeing your work positively affect your colleagues and patients, and thrive in a fast-paced entrepreneurial environment, this could be a great opportunity for you. In this role, you can have an impact both through many small tools and large product development. This role is a hybrid (onsite 2-3 days/week) position.

Projects you may work on include:

• Scaling and future-proofing core systems to support rapid volume growth, enterprise workloads, and long-term platform expansion.
• Building shared platform libraries and modular, domain-aligned services that reduce coupling, improve maintainability, and enable teams to integrate and deliver independently.
• Driving core architectural initiatives including service boundaries, data flows, observability patterns, and modernization of legacy components to enhance reliability and developer velocity.
• Establishing foundational infrastructure and automation that strengthens deployment workflows, improves system health visibility, and enables consistent, high-quality engineering execution.

Technologies we use include: Python, Django, Postgres, React, Typescript, AWS, Heroku, Salesforce, and emerging AI-assisted coding environments (e.g., Cursor, GitHub Copilot, Claude Code)

Responsibilities:

• Design, build, and operate scalable, high availability backend services, APIs, and data integrations that power customer facing product experiences
• Lead technical delivery across the full lifecycle: architecture, design, implementation, testing, deployment, and ongoing operations
• Collaborate closely with product, design, and cross functional engineering teams to deliver performant, reliable, and intuitive platform capabilities
• Develop clean abstractions and platform APIs that simplify complex LIS workflows while balancing developer velocity with long term system stability
• Build and maintain secure, reliable cloud infrastructure on AWS, including compute environments, networking, container orchestration, storage, and environment automation
• Implement CI/CD pipelines, Infrastructure as Code, configuration management, and automated environment provisioning to standardize and accelerate delivery
• Embed observability and operational excellence into the platform by default through robust monitoring, logging, alerting, and reliability patterns
• Ensure the scalability, maintainability, and overall health of backend and cloud systems as the platform grows to support large enterprise workloads and future global expansion
• Foster a culture of ownership, technical excellence, learning, and continuous improvement within the engineering team
• Apply AI-assisted tooling and workflows to improve developer productivity, automate routine engineering tasks, enhance code quality, and accelerate troubleshooting

Qualifications:

• 5 - 7 years of professional software development experience with a proven track record of delivering complex projects adhering to best practices
• Deep understanding and experience using web frameworks like Django and FastAPI
• Strong system design and architecture capabilities, applying domain-driven design to translate complex business domains into clear, scalable service and data boundaries.
• Familiarity with modern AI-driven development practices and tools.
• Strong foundation in cloud services, preferably AWS, including ECS, S3, AWS Batch, EC2, and AWS Lambda, enabling effective architecture and management of complex systems
• Excellent communication and collaboration skills, with the ability to work effectively in a team-oriented environment
• Excited about working in-person with our team in Menlo Park

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $300,806 per year, including a base pay range of $192,932 - $214,369 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are looking for a Bioinformatics Associate, Oncology to join our growing bioinformatics team. The bioinformatics team is responsible for analysis and pipeline development for our Northstar oncology products. Our sample volume is growing extremely quickly. As a Bioinformatics Associate, you will be working with a team of talented bioinformaticians to scale up our analysis pipeline to analyze tens of thousands of samples. The Bioinformatics Associate role is a full-time onsite position in Menlo Park, CA and reports to the Sr. Manager of Bioinformatics, Oncology.

Responsibilities:

• Perform analysis of clinical bioinformatics data while maintaining low turnaround time for data delivery
• Maintain and develop sophisticated and robust next-generation sequencing analysis pipeline
• Collaborate with other teams from CLIA lab, Software Engineering, Quality Assurance, and R&D to improve and scale our clinical workflows

Qualifications:

• BS or MS in Bioinformatics, Computational Biology, Computer Science, Bioengineering, Physics or related field
• Very strong programming skills in Python
• Comfortable working in UNIX command-line environments
• Experience deploying code in HPC or cloud computing environments
• Strong communication skills
• Great attention to detail
• Can work in the United States without immediate sponsorship (For applicants on student visas, post-graduation OPT is acceptable)

Nice-To-Haves:

• 2 years of research or industry experience in biotechnology
• Experience with software development in industry and ideally in a regulated environment
• Experience with Molecular biology lab techniques (DNA purification, PCR, electrophoresis) or next-generation sequencing library preparation
• Experience leading cross-functional projects involving teams of diverse backgrounds

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Free UNITY Complete NIPT testing for employees & spouses
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $115,655 per year, including a base pay range of $85,331 - $96,050 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are currently looking for a high-performing Senior Software Engineer  to join our dynamic software engineering team. Software engineers at BillionToOne work in highly collaborative and interdisciplinary teams of clinicians, computational biologists, and other engineers to robustly scale personalized genomic medicine to millions of patients. If you have experience performing in a full life-cycle development, love seeing your work positively affect your colleagues and patients, and thrive in a fast-paced entrepreneurial environment, this could be a great opportunity for you. In this role, you can have an impact both through many small tools and large product development. This role is a hybrid (onsite 2-3 days/week) position.

Projects you may work on include:

• Build a seamless digital experience so clinicians and patients across a diversity of care centers and socioeconomic status can have access to BillionToOne’s highly complex genetic testing
• Help digitize laborious and error-prone paper-based workflows at busy OBGYN clinics
• Enable better transfer of care through portable electronic medical records 
• Infuse joyful experiences into pregnancy

Technologies we use include: Python, Django, Postgres, React, Typescript, AWS, Salesforce, and emerging AI-assisted coding environments (e.g., Cursor, GitHub Copilot, Claude Code)

Responsibilities:

• Build and maintain robust applications and systems using React, Typescript, Django, Postgres, and other libraries.
• Collaborate with product design and product management to deliver delightful experiences for patients and providers.
• Foster a knowledge sharing culture within the team, contributing to the growth and development of colleagues through mentorship and collaborative learning.
• Demonstrate a creative and out-of-the-box mindset, offering innovative solutions and approaches to complex technical challenges.
• Prioritize quality by writing comprehensive unit tests and ensuring adequate test coverage across all components and modules.
• Demonstrate a strong sense of ownership and take responsibility for end-to-end project delivery. The ideal candidate will thrive in an environment where they have the autonomy to make informed decisions and take the initiative to drive projects forward.
• Champion engineering excellence through architectural best practices, code quality standards, and thoughtful code reviews that emphasize both functionality and security.
• Apply a security and compliance mindset ensuring adherence to relevant regulations while implementing appropriate safeguards for sensitive patient information.
• Confidently challenge ideas and assumptions from stakeholders when necessary, while at the same time, leverage their expertise and insights to improve the overall solution.

Requirements:

• 5+ years of professional software development experience with a proven track record of delivering complex projects and adhering to best practices
• Deep experience with modern frontend technologies, specifically with Typescript, React, and CSS-in-JS libraries
• Have implemented frontend architecture best practices such as component systems, npm workspaces, Storybook, and Playwright testing
• Experience with web frameworks such as Django
• Familiarity with modern AI-driven development practices and tools.
• Excited about working in-person with our team in Menlo Park

Nice-to-haves:

• Previous startup or entrepreneurial experience
• Experience in driving products from zero to one
• Familiarity with healthcare data and standards like FHIR and HL7
• Interest in engaging with and applying LLMs

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $297,321 per year, including a base pay range of $190,081 - $211,201 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are currently looking for a high-performing Senior Software Engineer, Digital Experiences to join our dynamic software engineering team. Software engineers at BillionToOne work in highly collaborative and interdisciplinary teams of clinicians, computational biologists, and other engineers to robustly scale personalized genomic medicine to millions of patients. If you have experience performing in a full life-cycle development, love seeing your work positively affect your colleagues and patients, and thrive in a fast-paced entrepreneurial environment, this could be a great opportunity for you. In this role, you can have an impact both through many small tools and large product development. This role is a hybrid (onsite 2-3 days/week) position.

Projects you may work on include:

• Build a seamless digital experience so clinicians and patients across a diversity of care centers and socioeconomic status can have access to BillionToOne’s highly complex genetic testing
• Help digitize laborious and error-prone paper-based workflows at busy Oncology clinics
• Enable better transfer of care through portable electronic medical records 

Technologies we use include: Python, Django, Postgres, React, Typescript, AWS, Salesforce, and emerging AI-assisted coding environments (e.g., Cursor, GitHub Copilot, Claude Code)

Responsibilities:

• Build and maintain robust applications and systems using React, Typescript, Django, Postgres, and other libraries.
• Collaborate with product design and product management to deliver delightful experiences for patients and providers.
• Foster a knowledge sharing culture within the team, contributing to the growth and development of colleagues through mentorship and collaborative learning.
• Demonstrate a creative and out-of-the-box mindset, offering innovative solutions and approaches to complex technical challenges.
• Prioritize quality by writing comprehensive unit tests and ensuring adequate test coverage across all components and modules.
• Demonstrate a strong sense of ownership and take responsibility for end-to-end project delivery. The ideal candidate will thrive in an environment where they have the autonomy to make informed decisions and take the initiative to drive projects forward.
• Champion engineering excellence through architectural best practices, code quality standards, and thoughtful code reviews that emphasize both functionality and security.
• Apply a security and compliance mindset ensuring adherence to relevant regulations while implementing appropriate safeguards for sensitive patient information.
• Confidently challenge ideas and assumptions from stakeholders when necessary, while at the same time, leverage their expertise and insights to improve the overall solution.

Requirements:

• 5+ years of professional software development experience with a proven track record of delivering complex projects and adhering to best practices
• Deep experience with modern frontend technologies, specifically with Typescript, React, and CSS-in-JS libraries
• Have implemented frontend architecture best practices such as component systems, npm workspaces, Storybook, and Playwright testing
• Experience with web frameworks such as Django
• Familiarity with modern AI-driven development practices and tools.
• Excited about working in-person with our team in Menlo Park

Nice-to-haves:

• Previous startup or entrepreneurial experience
• Experience in driving products from zero to one
• Familiarity with healthcare data and standards like FHIR and HL7
• Interest in engaging with and applying LLMs

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $307,321 per year, including a base pay range of $190,081 - $211,201 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are looking for a passionate and energetic Office Manager to become the go-to person for all office management operations in our state-of-the-art facility and manage our Menlo Park facilities and ensure employee happiness is maximized at all times. The ideal candidate will have the ability to work cross-functionally between many departments to help keep our office. The Office Manager position is an onsite position and reports to the Senior Director of Supply Chain.

Responsibilities:

• Own and manage daily office operations and guest experience
• Contribute to and collaborate with the team by assisting in the day-to-day operations of a rapidly growing molecular diagnostics lab’s office space
• Responsible for maintaining, ordering, and stocking of snacks and office supplies
• Greet and direct visitors to BillionToOne in a professional and friendly manner
• Assist in scheduling and coordinating building tours, interviews, and company site visits
• Partners cross functionally and support event planning and culture initiatives
• Help to streamline processes and set-up systems that keep a fast-growing company operating efficiently
• Maintain relationships with breakroom & office supply vendors and serve as the primary point of contact across various functions
• Assist with creating and executing a calendar of creative employee appreciation events (birthdays, anniversaries)
• Liaise with business leaders and key stakeholders to support people team initiatives and new hire on-boarding (temp badge access, office tours, etc.)
• Advance other activities within the company as needed
• Assist with creating and executing a calendar of creative employee appreciation events (birthdays, anniversaries)
• Help keep the office pleasant and productive

Qualifications:

• 1+ years experience managing an office with a fast paced environment with over 100 employees
• You embody our culture of kindness and ambition and are excited by the challenge of making an office an incredible place for our employees to gather and work
• You have a strong sense of initiative, interested in growing and taking on projects outside of scope
• You have the ability to collaborate well cross functionally to improve office operations
• You have excellent communication skills, in verbal and written form (i.e., clarity of thought, structured, rigorous)
• You're comfortable with ambiguity
• You have a track record of managing offices efficiently and seamlessly
• You like to go above and beyond and are eager to learn new things
• Knowledge of Slack, Microsoft Word, Excel, Powerpoint
• Ability to lift 25 pounds

Nice to Have:

• College degree preferred but not required

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Free UNITY Complete NIPT testing for employees & spouses
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $98,427 per year, including a base pay of $80,388 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Responsibilities:

• Apply sound engineering practices to scale, optimize, and improve molecular biology methods.
• Conduct experiments to identify, isolate, and confirm root causes of process errors in our high-throughput molecular biology lab.
• Develop methods to compile and analyze large amounts of process data to assess for process stability, trending, and areas for improvement.
• Develop and implement software tools to aid in efficient sample processing within the clinical laboratory. 
• Develop, implement, and use software tools to quantitatively analyze process efficiency and sources of error, to require moderate proficiency in R or Python.
• Identify root causes for process and instrument errors and develop short term and long term solutions. 
• Develop effective training plans for clinical personnel on modified/improved workflows.
• Support transfer of new technology from Research and Development teams to the CLIA lab.
• Generate proper documentation for all troubleshooting and qualification.

Requirements:

• Bachelor’s degree or equivalent degree in biology or clinical related sciences
• At least 6 months of experience with molecular biology techniques in a research or clinical laboratory
• Excellent attention to detail
• Effective written and verbal communication skills
• Possess logical troubleshooting skills
• Previous automation or clinical laboratory experience is preferred

Nice-To-Haves:

• Start-up experience
• Experience with next-generation sequencing (NGS)
• Knowledge of molecular oncology
• Experience in a cell-free DNA setting

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Free UNITY Complete NIPT testing for employees & spouses
• Supplemental fertility benefits coverage
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses) (2) generous equity options offering, on top of (3) industry leading company benefits (free healthcare options, 401k match, very generous fully paid paternal leave etc.).

For this position, we offer a total compensation package of $104,322 per year, including a base pay range of $75,029-$85,748 per year.

As BillionToOne scales rapidly, we are building a world-class Commercial Data & Applied AI team. We are currently seeking a highly motivated Senior AI Engineer I to support the design and implementation of AI and automation solutions that optimize operations across our commercial, billing, and customer experience teams.

This is a full-time senior role for engineers excited about applying LLMs, AI, and automation to real-world business challenges in healthcare. You will have the opportunity to join a new team and help shape the vision and culture. You will collaborate cross-functionally with stakeholders in Sales, Marketing, Revenue Operations, Billing, Customer Experience, and IT to identify high-impact opportunities for AI-driven solutions that improve scalability and efficiency.

We are builders at heart. We value a strong sense of ownership, intellectual curiosity, and a bias toward action.

This is a hybrid role requiring 2-3 days per week on-site in Menlo Park with the team.

Responsibilities:

• Build and deploy LLM-powered applications (retrieval systems, AI agents, workflow automation, vector storage) that integrate with internal systems and data sources
• Partner with business stakeholders to identify automation opportunities, scope requirements, and define success metrics
• Build lightweight data pipelines and analytics to support AI applications and measure their impact
• Own projects end-to-end: from prototyping and iteration through production deployment and monitoring
• Establish best practices for prompt engineering, evaluation, and responsible AI use as the team scales
• Develop and lead internal training sessions on LLM fundamentals, prompt engineering, and AI-assisted development tools

Qualifications:

• 5+ years of experience in software engineering, data science, or ML engineering
• Hands-on experience building applications with LLM APIs (OpenAI, Anthropic, etc.)
• Strong Python proficiency and comfort with SQL and relational databases
• Experience deploying and maintaining production systems
• Familiarity with AWS
• Excellent communication skills and ability to translate business problems into technical solutions
• Self-directed and comfortable with ambiguity in a 0-to-1 environment

Nice-To-Haves:

• Previous entrepreneurial experience
• Experience with retrieval architectures, vector databases, and embedding models
• Familiarity with agent frameworks or workflow orchestration tools
• Experience with traditional ML frameworks (scikit-learn, PyTorch, TensorFlow)
• Prior work in healthcare, biotech, or other regulated industries

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $280,705 per year, including a base pay range of $174,241 - $200,641 per year.

BillionToOne is seeking a Senior Scientist, Real-World Evidence, Oncology to help unlock insights from our rapidly growing dataset of genomic profiles and real-world clinical data.

This role sits at the intersection of AI, genomics, oncology research, and clinical data science. The scientist will develop models and analytical approaches that transform genomic and clinical data into actionable insights for research, clinical decision support, and future data-driven products. The role will also build AI tools that support internal scientific operations—such as literature discovery, variant interpretation, and clinical trial or guideline tracking—while helping lay the foundation for future real-world data products leveraging BillionToOne’s unique genomics and clinical dataset for pharmaceutical and research partners.

A unique aspect of this role is the opportunity to work with BillionToOne’s proprietary dataset, combining genomic sequencing results from our Northstar oncology platform with real-world medical records. Leveraging this rich dataset, the scientist will generate clinically meaningful insights and real-world evidence (RWE) to improve treatment decisions and advance precision oncology. This role will report to the Chief Product Officer.

Responsibilities:

• Leverage BillionToOne’s integrated datasets of Northstar genomic sequencing results and real-world clinical data from patients we serve to generate clinically meaningful insights and real-world evidence (RWE).
• Develop AI and machine learning approaches that uncover patterns across genomic alterations, treatment histories, and patient outcomes, supporting internal research and improving how genomic test results inform clinical decision-making.
• Develop AI-powered tools that enhance the clinical utility of BillionToOne’s diagnostics, including systems that surface relevant medical records, literature evidence, clinical trials, and guideline information alongside Northstar test results to assist oncologists in making more personalized treatment decisions.

Qualifications:

• PhD in biology, biomedical sciences, medicine, computational biology, biomedical informatics, or a related field is required.
• Deep understanding of genomic data, oncology biology, and clinical medical data.
• Experience applying AI, machine learning, or advanced analytics to biomedical or healthcare datasets.
• Strong programming and data science skills (Python and modern ML frameworks).
• Experience working with real-world clinical datasets (EHR, clinical records, registries, or similar).
• Ability to analyze and integrate multimodal biomedical datasets, including genomics, clinical data, and biomedical literature.
• Strong problem-solving skills and ability to collaborate across interdisciplinary teams, including clinical, bioinformatics, and product groups.

Experience:

• Experience working with oncology real-world datasets.
• Experience applying large language models (LLMs) or retrieval-based AI systems to biomedical knowledge extraction.
• Experience integrating genomic sequencing data with clinical outcomes data.
• Track record of research publications or applied AI systems in healthcare or life sciences.

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $251,855 per year, including a base pay range of $139,340 - $160,777 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

BillionToOne is seeking a Senior Finance Systems Analyst who will play a pivotal role in driving technology solutions across our finance function. This is a hands-on manager-level role, responsible for the administration, optimization, and integration of financial systems to support scaling operations and compliance with public company standards.

You’ll act as the key liaison between Accounting, Billing, and IT to ensure that systems and projects are aligned with business goals and internal control requirements. Your expertise in ERP systems, audit compliance, and cross-functional collaboration will be essential in enhancing the efficiency, accuracy, and control of our financial processes.

Responsibilities:

• Financial Systems Support & Administration
  • Assist with the administration and day-to-day support of financial technologies, including ERP systems and related finance tools.
  • Manage NetSuite configurations such as workflows, saved searches, roles, and user access under guidance from senior team members.
  • Support implementation and enhancement of system features and integrations across Finance and Supply Chain.
  • Identify opportunities to streamline processes and improve automation within finance systems.
  • Assist with data integrity, system maintenance, and troubleshooting for finance-related applications.
  • Support data integrations and work with IT on resolving integration-related issues.
• Cross-Functional Partnership
  • Work with Accounting, HR, Billing, and IT to translate business needs into system requirements and functional updates.
  • Assist Accounting during the monthly/quarterly close cycle by ensuring data accuracy and addressing system-related issues.
  • Support reporting, analysis, and planning tool integrations as needed.
  • Contribute to documentation of system requirements, test cases, and change requests.
  • Help coordinate system updates, testing, and deployment activities for finance system initiatives.
• Compliance & Controls
  • Maintain systems and processes in alignment with internal control frameworks and SOX readiness efforts.
  • Support audit activities by preparing system documentation, ensuring accuracy of financial system data, and providing required system access evidence.
  • Assist in maintaining IT SOX documentation related to finance systems.

Qualifications:

• 4–5+ years of experience supporting financial systems, preferably with hands-on NetSuite administration.
• Experience supporting financial audits and understanding of internal controls (SOX exposure preferred).
• Bachelor’s degree in Accounting, Information Systems, Computer Science, or a related field.
• Strong understanding of financial processes and reporting requirements.
• Demonstrated ability to support finance system enhancements and assist with system projects.
• Excellent analytical and problem-solving skills with strong attention to detail.
• Ability to manage multiple priorities and work in a fast-paced, dynamic environment.
• Strong communication skills and ability to work cross-functionally with both technical and non-technical teams.
• Experience with AI tools and automation.

We are currently looking for a high-performing Senior Software Engineer  to join our dynamic software engineering team. Software engineers at BillionToOne work in highly collaborative and interdisciplinary teams of clinicians, computational biologists, and other engineers to robustly scale personalized genomic medicine to millions of patients. If you have experience performing in a full life-cycle development, love seeing your work positively affect your colleagues and patients, and thrive in a fast-paced entrepreneurial environment, this could be a great opportunity for you. In this role, you can have an impact both through many small tools and large product development. This role is a hybrid (onsite 2-3 days/week) position.

Projects you may work on include:

• Build a seamless digital experience so clinicians and patients across a diversity of care centers and socioeconomic status can have access to BillionToOne’s highly complex genetic testing
• Help digitize laborious and error-prone paper-based workflows at busy OBGYN clinics
• Enable better transfer of care through portable electronic medical records 
• Infuse joyful experiences into pregnancy

Technologies we use include: Python, Django, Postgres, React, Typescript, AWS, Salesforce, and emerging AI-assisted coding environments (e.g., Cursor, GitHub Copilot, Claude Code)

Responsibilities:

• Build and maintain robust applications and systems using React, Typescript, Django, Postgres, and other libraries.
• Collaborate with product design and product management to deliver delightful experiences for patients and providers.
• Foster a knowledge sharing culture within the team, contributing to the growth and development of colleagues through mentorship and collaborative learning.
• Demonstrate a creative and out-of-the-box mindset, offering innovative solutions and approaches to complex technical challenges.
• Prioritize quality by writing comprehensive unit tests and ensuring adequate test coverage across all components and modules.
• Demonstrate a strong sense of ownership and take responsibility for end-to-end project delivery. The ideal candidate will thrive in an environment where they have the autonomy to make informed decisions and take the initiative to drive projects forward.
• Champion engineering excellence through architectural best practices, code quality standards, and thoughtful code reviews that emphasize both functionality and security.
• Apply a security and compliance mindset ensuring adherence to relevant regulations while implementing appropriate safeguards for sensitive patient information.
• Confidently challenge ideas and assumptions from stakeholders when necessary, while at the same time, leverage their expertise and insights to improve the overall solution.

Requirements:

• 5+ years of professional software development experience with a proven track record of delivering complex projects and adhering to best practices
• Deep experience with modern frontend technologies, specifically with Typescript, React, and CSS-in-JS libraries
• Have implemented frontend architecture best practices such as component systems, npm workspaces, Storybook, and Playwright testing
• Experience with web frameworks such as Django
• Familiarity with modern AI-driven development practices and tools.
• Excited about working in-person with our team in Menlo Park

Nice-to-haves:

• Previous startup or entrepreneurial experience
• Experience in driving products from zero to one
• Familiarity with healthcare data and standards like FHIR and HL7
• Interest in engaging with and applying LLMs

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $297,321 per year, including a base pay range of $190,081 - $211,201 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are seeking a highly driven leader for one of the most critical and high-impact roles at BillionToOne: the Senior Director of Product Management, Oncology. In this role, you will essentially act as the General Manager for the entire oncology product line, owning the product roadmap for Northstar, our liquid biopsy product for therapy selection and monitoring. This is a unique opportunity for a GM-like product leader with strong end-to-end ownership, exceptional people management skills, and the ability to be both strategic and hands-on.

The ideal candidate is entrepreneurial, thrives in a fast-paced, dynamic environment, and can navigate the complexities of scaling innovative products in a competitive market. You will lead new assay development, drive product enhancements, and collaborate with diverse teams, including R&D, clinical, and engineering. You’ll be responsible for ensuring our oncology products not only meet market demands but set the standard in the industry.

This role is an hybrid (onsite 3 days/week) position and reports directly to the Chief Product Officer.

Responsibilities:

• GM Ownership: Own the oncology product line from top to bottom, ensuring long-term strategic success while handling day-to-day tactical responsibilities.
• Market Expert & Product Visionary: Be the company’s leading expert on user needs, market trends, and how BillionToOne’s technology can solve critical problems in oncology diagnostics.
• Product Launch & Execution: Lead product launch strategies, overseeing every element from assay development to software apps, regulatory constraints, and customer experience.
• People Leadership: Manage and inspire a cross-functional team of R&D, clinical, engineering, and commercial experts, aligning their efforts towards the product’s success.
• User Experience Champion: Design and deliver a seamless user experience across the entire testing process, in collaboration with UX designers and stakeholders.
• Drive Continuous Improvement: Monitor product performance, user feedback, and market shifts, making data-driven decisions to enhance product offerings and maintain leadership in the market.

Qualifications:

• 5-10 years of product management experience with demonstrated end-to-end ownership of complex product lines
• Proven experience launching diagnostic testing products (oncology or NGS-based diagnostics preferred)
• GM-like mindset with strategic vision and hands-on execution skills
• Excellent people management and leadership capabilities across cross-functional teams
• Strong background in product launch strategy, go-to-market execution, and program management
• On-site position (relocation to SF Bay Area required)

Nice-To-Haves:

• Another advanced degree (Masters/PhD) in molecular biology, bioengineering, medicine, chemical biology, or a related field is strongly preferred 
• Experience with launching and managing NGS-based diagnostic testing assays is a strong plus

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Free daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $474,416 per year, including a base pay range of $257,243 - $278,680 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

BillionToOne is seeking a Senior Scientist, Real-World Evidence, Oncology to help unlock insights from our rapidly growing dataset of genomic profiles and real-world clinical data.

This role sits at the intersection of AI, genomics, oncology research, and clinical data science. The scientist will develop models and analytical approaches that transform genomic and clinical data into actionable insights for research, clinical decision support, and future data-driven products. The role will also build AI tools that support internal scientific operations—such as literature discovery, variant interpretation, and clinical trial or guideline tracking—while helping lay the foundation for future real-world data products leveraging BillionToOne’s unique genomics and clinical dataset for pharmaceutical and research partners.

A unique aspect of this role is the opportunity to work with BillionToOne’s proprietary dataset, combining genomic sequencing results from our Northstar oncology platform with real-world medical records. Leveraging this rich dataset, the scientist will generate clinically meaningful insights and real-world evidence (RWE) to improve treatment decisions and advance precision oncology. This role will report to the Chief Product Officer.

Responsibilities:

• Leverage BillionToOne’s integrated datasets of Northstar genomic sequencing results and real-world clinical data from patients we serve to generate clinically meaningful insights and real-world evidence (RWE).
• Develop AI and machine learning approaches that uncover patterns across genomic alterations, treatment histories, and patient outcomes, supporting internal research and improving how genomic test results inform clinical decision-making.
• Develop AI-powered tools that enhance the clinical utility of BillionToOne’s diagnostics, including systems that surface relevant medical records, literature evidence, clinical trials, and guideline information alongside Northstar test results to assist oncologists in making more personalized treatment decisions.

Qualifications:

• PhD in biology, biomedical sciences, medicine, computational biology, biomedical informatics, or a related field is required.
• Deep understanding of genomic data, oncology biology, and clinical medical data.
• Experience applying AI, machine learning, or advanced analytics to biomedical or healthcare datasets.
• Strong programming and data science skills (Python and modern ML frameworks).
• Experience working with real-world clinical datasets (EHR, clinical records, registries, or similar).
• Ability to analyze and integrate multimodal biomedical datasets, including genomics, clinical data, and biomedical literature.
• Strong problem-solving skills and ability to collaborate across interdisciplinary teams, including clinical, bioinformatics, and product groups.

Experience:

• Experience working with oncology real-world datasets.
• Experience applying large language models (LLMs) or retrieval-based AI systems to biomedical knowledge extraction.
• Experience integrating genomic sequencing data with clinical outcomes data.
• Track record of research publications or applied AI systems in healthcare or life sciences.

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered at 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Retirement savings program including a 4% Company match
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $251,855 per year, including a base pay range of $139,340 - $160,777 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are looking for a detail oriented Accessioner (Part-Time) to be responsible for assisting with the day-to-day laboratory preparation and equipment maintenance in the Clinical Laboratory. The Accessioner will also be responsible for the accessioning of clinical specimens, performing quality assurance procedures, and complying with all local, state, and federal laboratory requirements. The nature of the work performed by an Accessioner requires excellent attention to detail, effective written and verbal communication skills, the ability to multitask, and the ability to work both independently and in a team environment.

This is a part time position (24 hours/week maximum) with Saturday 8am-4:30pm required. 

Responsibilities:

• Perform sample accessioning procedures according to the laboratory’s standard operating procedures
• Prepare documents for equipment and personnel records
• Perform and document routine maintenance of equipment
• Prepare other clinical documentation as required and assigned
• Clean labware, equipment, and benches
• Prepare reagents required for testing
• Write and review controlled documents as assigned

Qualifications:

• Bachelor’s degree or equivalent in biology-adjacent field, or student currently pursuing biology degree
• Able to integrate and apply feedback in a professional manner
• Strong attention to detail
• Able to manage daily specimen processing needs with high emphasis on quality
• Able to analyze and problem solve basic issues that impact test performance
• Able to proactively communicate consistently, clearly, and honestly

Nice-To-Haves:

• Clinical Laboratory experience or equivalent high complexity and volume laboratory experience
• Laboratory experience within the last year preferred

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay and (2) the opportunity for professional growth.

For this position, the base pay rate is $21.12 per hour.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We're seeking a multidisciplinary designer to shape brand communications across every touchpoint—from digital campaigns to event experiences, motion graphics to sales enablement. This role sits at the intersection of creative execution and strategic thinking—translating our breakthrough science into visual stories that resonate with providers, patients, and partners.

As a key contributor to our growing creative team, you'll bring concepts to life across channels while helping evolve our visual systems. You'll collaborate with marketing, product, and sales teams to create work that reflects the precision, humanity, and impact of our innovations. This is a hybrid position (3 days per week at our Menlo Park facilities.)

Responsibilities:

• Creative Execution and Production
  
  • Design and produce high-impact creative across digital and print: display ads, landing pages, email campaigns, brochures, event collateral, and social media content
  • Execute within existing brand systems while contributing ideas to evolve and strengthen our visual platform
  • Deliver polished, production-ready files that maintain quality and consistency across all touchpoints
  • Support photography direction, video editing, and motion design for campaigns and content initiatives
• Collaboration and Problem-Solving
  
  • Partner with marketing, sales, research, and product teams to understand objectives and craft effective visual solutions
  • Participate in creative development and brainstorming sessions, bringing strong design judgment and fresh perspectives
  • Translate complex scientific concepts into accessible, engaging visual communications
  • Support cross-functional teams with brand-aligned materials that drive engagement and performance
• Brand Development and Systems Thinking
  
  • Help expand our visual platform across direct marketing, growth campaigns, brand storytelling, content, and events
  • Contribute to the evolution of design systems and brand guidelines as we scale
  • Ensure brand consistency while finding opportunities for creative expression within our visual language
  • Build organized asset libraries and maintain design documentation
• Growth and Learning
  • Develop your craft across multiple disciplines: brand design, digital advertising, motion graphics, and experiential design
  • Seek feedback and mentorship to accelerate your growth toward senior-level design roles
  • Stay current with design trends, tools, and techniques relevant to healthcare and science communication

Qualifications:

• 2–3 years of professional design experience in-house, at agencies, or freelance
• Bachelor's degree in Graphic Design, Visual Communication, or related field
• Portfolio demonstrating brand storytelling, strategic thinking, and execution across digital and print channels
• Experience designing for healthcare, science, biotech, or technology sectors a strong plus
• Background working across multiple formats: digital advertising, print collateral, motion graphics, social media, and video
• Proficiency in Figma and Adobe Creative Suite: Photoshop, Illustrator, InDesign
• Experience with motion and video tools: After Effects, Premiere Pro, DaVinci Resolve, or similar platforms
• Understanding of design systems, component libraries, and scalable brand guidelines
• Familiarity with digital marketing best practices and platform-specific requirements (social, display, email)

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $126,161 per year, including a base pay range of $84,480 - $105,601 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are currently looking for a high-performing Senior Software Engineer, Digital Experiences to join our dynamic software engineering team. Software engineers at BillionToOne work in highly collaborative and interdisciplinary teams of clinicians, computational biologists, and other engineers to robustly scale personalized genomic medicine to millions of patients. If you have experience performing in a full life-cycle development, love seeing your work positively affect your colleagues and patients, and thrive in a fast-paced entrepreneurial environment, this could be a great opportunity for you. In this role, you can have an impact both through many small tools and large product development. This role is a hybrid (onsite 2-3 days/week) position.

Projects you may work on include:

• Build a seamless digital experience so clinicians and patients across a diversity of care centers and socioeconomic status can have access to BillionToOne’s highly complex genetic testing
• Help digitize laborious and error-prone paper-based workflows at busy Oncology clinics
• Enable better transfer of care through portable electronic medical records 

Technologies we use include: Python, Django, Postgres, React, Typescript, AWS, Salesforce, and emerging AI-assisted coding environments (e.g., Cursor, GitHub Copilot, Claude Code)

Responsibilities:

• Build and maintain robust applications and systems using React, Typescript, Django, Postgres, and other libraries.
• Collaborate with product design and product management to deliver delightful experiences for patients and providers.
• Foster a knowledge sharing culture within the team, contributing to the growth and development of colleagues through mentorship and collaborative learning.
• Demonstrate a creative and out-of-the-box mindset, offering innovative solutions and approaches to complex technical challenges.
• Prioritize quality by writing comprehensive unit tests and ensuring adequate test coverage across all components and modules.
• Demonstrate a strong sense of ownership and take responsibility for end-to-end project delivery. The ideal candidate will thrive in an environment where they have the autonomy to make informed decisions and take the initiative to drive projects forward.
• Champion engineering excellence through architectural best practices, code quality standards, and thoughtful code reviews that emphasize both functionality and security.
• Apply a security and compliance mindset ensuring adherence to relevant regulations while implementing appropriate safeguards for sensitive patient information.
• Confidently challenge ideas and assumptions from stakeholders when necessary, while at the same time, leverage their expertise and insights to improve the overall solution.

Requirements:

• 5+ years of professional software development experience with a proven track record of delivering complex projects and adhering to best practices
• Deep experience with modern frontend technologies, specifically with Typescript, React, and CSS-in-JS libraries
• Have implemented frontend architecture best practices such as component systems, npm workspaces, Storybook, and Playwright testing
• Experience with web frameworks such as Django
• Familiarity with modern AI-driven development practices and tools.
• Excited about working in-person with our team in Menlo Park

Nice-to-haves:

• Previous startup or entrepreneurial experience
• Experience in driving products from zero to one
• Familiarity with healthcare data and standards like FHIR and HL7
• Interest in engaging with and applying LLMs

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $307,321 per year, including a base pay range of $190,081 - $211,201 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We are looking for a driven Clinical Laboratory Scientist (with California Clinical Laboratory Scientist License) to perform Northstar. You will join our growing superstar CLIA team responsible for end-to-end processing of cancer blood samples in a high complexity, high-growth CLIA setting. The Clinical Laboratory Scientist is an onsite position.

Shift Hours: Tues - Sat PM (1:30-10 PM)

• Weekday PM, 20%
• Weekend PM, 25%

Responsibilities:

• Performs clinical laboratory assays to provide data for diagnosis, treatment, and prevention of disease
• Performs quality control studies to ensure the accuracy of clinical data
• Verifies instrument performance by checking and calibrating specific lab instruments and documents data
• Organizes and contributes to R&D to CLIA tech transfer and troubleshooting, training, and validations

Qualifications:

• Bachelor's degree in the chemical, physical or biological sciences
• 1-2 years of CLS experience in a clinical setting
• A current California Clinical Laboratory Scientist License that meets requirements for Testing Personnel under CLIA regulations (42 CFR, part 493) (ASCP, CGMBS or generalist license is required)
• Hands-on training and experience with manual molecular biology protocols, including DNA extraction and PCR
• Advanced knowledge of Google Docs, Word, Excel, basic statistics and familiarity with LIMS systems
• Strong attention to detail and ability to work flexibly and well under given timeframes
• Self-starter and dynamic team player with excellent verbal and written skills

Nice-To-Haves:

• Start-up experience
• Knowledge of cancer biology
• Experience in a cell-free DNA setting

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

"}" data-sheets-userformat="{"2":769,"3":{"1":0},"11":4,"12":0}">At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of up to $156,194 per year, including an hourly rate of $59.14 - $67.29 per hour. Compensation is commensurate with experience and leveling.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

We're seeking an exceptional Lead UX Designer to own the end-to-end experience strategy and execution for our prenatal diagnostic platform, Unity. This role sits at the intersection of cutting-edge genomics and human-centered design - leading the translation of complex molecular diagnostics into seamless, trustworthy experiences that empower clinicians, patients, and operational teams.

As a key member of our product team, you'll lead design from strategic insights through final production, applying systems thinking to design across an interconnected healthcare ecosystem that spans lab processes, electronic health records, provider networks, and patient touchpoints. You'll bridge scientific complexity and clinical reality while guiding design team members and elevating the craft of the entire organization. This is a hybrid position (2-3 days per week at our Menlo Park facilities.)

Responsibilities:

• Strategic Design Leadership
  
  • Own the complete UX vision and strategy for Unity's patient and provider platforms, from research insights through final implementation
  • Partner with product leadership to shape roadmaps, define priorities, and determine phased approaches that balance user needs, technical feasibility, and business goals
  • Apply systems thinking to visualize and simplify complex relationships between patients, providers, lab processes, payer requirements, and data systems
  • Transform scientific complexity into intuitive digital experiences that build trust and understanding
  • Translate product strategy into actionable design initiatives that connect user journeys with clinical workflow realities
• End to End Design Execution
  
  • Lead the complete design process from discovery and research through wireframing, prototyping, user testing, and final production-ready deliverables
  • Create and maintain high-quality design artifacts: user flows, journey maps, wireframes, prototypes, and design system components that capture the full patient and clinician experience
  • Own in-product microcopy and content strategy, ensuring every word builds clarity, confidence, and trust
  • Drive the evolution of Unity's design system, promoting consistency, scalability, and craft in partnership with branding and marketing teams
  • Ensure accessibility, regulatory compliance, and ethical considerations are integrated into every design decision
  • Lead user research initiatives to uncover insights that drive product strategy and design decisions
  • Advocate for evidence-based design grounded in rigorous user research and testing methodologies
  • Synthesize insights from clinicians, patients, and operational teams to identify unmet needs and design opportunities
  • Champion the user perspective in cross-functional discussions, balancing clinical requirements, technical constraints, and business objectives
• Team Leadership and Collaboration
  
  • Oversee and mentor junior designers and UX contractors, providing clear direction, constructive feedback, and opportunities for growth
  • Build a culture of design excellence, systems thinking, and user advocacy within the design team and across the organization
  • Partner with engineers to ensure the experiential quality of what ships matches design intent and maintains high craft standards
  • Present and defend design decisions to stakeholders across product, clinical, and executive leadership
  • Collaborate with product managers, engineers, clinicians, and genetic counseling teams to align design work with broader organizational goals
  • Identify opportunities and drive initiatives independently while maintaining strategic alignment across teams

Qualifications:

• 7–10 years of professional experience in UX, product design, or service design
• 3+ years in leadership roles with demonstrated ability to own design strategy and guide team members
• Proven track record designing in healthcare, biotech, or similarly complex regulated environments
• An exceptional portfolio demonstrating systems-level thinking, strategic leadership, and user-centered problem solving from research through final execution
• Experience in both B2B and B2C healthcare product contexts preferred
• Background working with AI-powered product experiences a plus
• Track record of partnering with product management on prioritization and phased delivery approaches
• Expert-level skills in design and prototyping tools: Figma, Sketch, Miro, or similar platforms
• Deep understanding of user research methodologies, from generative research to usability testing
• Mastery of information architecture, interaction design principles, and UX best practices
• Strong grasp of accessibility standards (WCAG) and healthcare regulatory requirements (HIPAA, FDA)
• Experience creating and maintaining design systems at scale

Benefits And Perks:

• Working alongside brilliant, kind, passionate and dedicated colleagues, in an empowering environment, toward a global vision, striving for a future in which transformative molecular diagnostics can help millions of patients
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousands patients
• Multiple medical benefit options; employee premiums paid 100% of select plans, dependents covered up to 80%
• Extremely generous Family Bonding Leave for new parents (16 weeks, paid at 100%)
• Supplemental fertility benefits coverage 
• Retirement savings program including a 4% Company match
• Increase paid time off with increased tenure
• Latest and greatest hardware (laptop, lab equipment, facilities)
• Daily on-site lunches provided from top eateries
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of a (1) base pay range (actual amount offered is based on experience and salary/equity options split that the candidate chooses), (2) generous equity options offering, (3) corporate bonus program, on top of (4) industry leading company benefits (free healthcare options, 401k match, very generous fully paid parental leave, etc.).

For this position, we offer a total compensation package of $317,881 per year, including a base pay range of $179,521 - $211,201 per year.

BillionToOne is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

As BillionToOne scales rapidly, we are building a world-class Commercial Data & Applied AI team. We are seeking a motivated AI Engineering Intern to support the design and implementation of AI and automation solutions that optimize operations across our commercial, billing, and customer experience teams.

This is an internship for those excited about applying LLMs, AI, ML, and automation to real-world business challenges in healthcare. You will have the opportunity to learn from experienced engineers on a new team while making meaningful contributions to high-impact projects. You will work cross-functionally with stakeholders in Sales, Marketing, Revenue Operations, Billing, Customer Experience, and IT to support AI-driven solutions that improve scalability and efficiency.

We are builders at heart. We value a strong sense of ownership, intellectual curiosity, and a bias toward action.

This is a hybrid role requiring 2–3 days per week on-site in Menlo Park with the team.

Responsibilities:

• Contribute to the development of LLM-powered applications (retrieval systems, AI agents, workflow automation, vector storage) that integrate with internal systems and data sources
• Work with business stakeholders and senior engineers to identify automation opportunities and help define requirements
• Assist in building lightweight data pipelines and analytics to support AI applications and measure their impact
• Contribute to projects across the development lifecycle  from prototyping and iteration through testing and deployment

Qualifications:  

• Currently pursuing (or recently completed) a Bachelor's, Master's degree or PhD
• Familiarity with Python and basic comfort with SQL
• Exposure to LLM APIs (OpenAI, Anthropic, etc.) through coursework, personal projects, or hackathons
• Strong communication skills and eagerness to learn how business problems translate into technical solutions
• Self-directed and comfortable asking questions in a fast-paced, ambiguous environment

Nice-to-Haves:

• Personal projects, hackathon experience, or coursework involving LLMs or ML
• Exposure to retrieval architectures, vector databases, or embedding models
• Familiarity with cloud platforms (AWS, GCP, or Azure)
• Experience with ML frameworks (scikit-learn, PyTorch, TensorFlow)
• Interest in healthcare, biotech, or regulated industries

Benefits And Perks:

• Working with a team of ‘rockstars’ who bring out the best in everyone
• Open, transparent culture that includes weekly Town Hall meetings
• The ability to indirectly or directly change the lives of hundreds of thousand patients
• Free daily on-site lunches provided from top eateries
• Latest and greatest hardware (laptop, lab equipment, facilities)
• A variety of perks on campus (state of the art gym, restaurant)
• Free on-site EV charging (compatible with all EVs, including Tesla)

At BillionToOne, we are proud to offer a combination of (1) competitive base pay, and (2) the opportunity for professional growth.

For this position, the base pay rate is $25 per hour.