Position Overview:

Beam is seeking a highly motivated individual to join our Supply Chain team. The Supply Planning & Network leader will be responsible managing the global supply network performance by conducting risk-based inventory reviews and developing strategic options to address demand uncertainties and enhance network capabilities. He/she will be accountable to ensure uninterrupted supply of clinical and future commercial products via Beam’s S&OP process. This role will report to the Sr. Director of Global Supply Chain Planning and partner with TechOps, Clinical Ops, Commercial Patient Ops, Quality, Finance, and CMC teams to lead short-term integrated production planning and long-range strategic supply chain planning of Beam’s product portfolio. The role will be responsible for leading a global inventory management program to ensure critical material availability at Beam NC & CDMO mfg sites. The role will be integral to enhancing site planning and scheduling capabilities at Beam’s mfg site in Durham, NC and partnering with SAP business lead on further advancing technology capabilities. The ideal candidate will have a demonstrated track record of leading in a dynamic environment. They will also possess the ability to successfully interface with multidisciplinary teams and build strong cross functional relationships.

Responsibilities:

• Production & Capacity Planning: Develop and maintain a rolling 12–24-month master production schedule (MPS) aligned with demand forecasts and manufacturing constraints.
• External Network Collaboration: Lead planning and partner with key stakeholders to ensure supply continuity across the Contract Manufacturing Organizations (CMOs) and 3PLs.
• Sales & Operations Planning (S&OP): Drive the monthly S&OP cycle, including rough-cut capacity planning and scenario analysis. Partner cross-functionally to refine demand forecasts and execute supply network analysis to support both tactical and strategic goals.
• Inventory Optimization: Ensures appropriate inventory levels to minimize excess while preventing stockouts, specifically managing shelf-life/expiry for temperature-sensitive products like Critical Materials (pDNA, mRNA, gRNA, mAb, lipids), Drug Substance, and Bulk/Finished Drug Product.
• Clinical/Launch Readiness: Orchestrate supply for clinical trials or support new product introductions (NPI) and commercial launches.
• Risk Management: Proactively identify supply disruptions and develop mitigation strategies or business continuity plans.
• Process Improvement: Drive Global Supply Chain excellence through project management, process enhancement, and the deployment of digital tools that streamline business execution and strategic decision-making.
• Metrics: Leverage data-driven KPIs to track performance, ensuring accountability and optimizing the balance between operational efficiency and financial health.
• Systems: Optimize supply and inventory planning accuracy through utilization of SAP, driving improved stock maintenance and network visibility. Spearhead the design and execution of SAP enhancements, including Integrated Business Planning (IBP) and Jurisdictional Control (JC), to streamline end-to-end supply chain functions.
• Other duties as assigned.

Qualifications:

• BS/BA degree in Business, Science, Engineering or related field with 8-10+ years of experience in global supply chain from pharma, biotech or cell & gene therapy companies.
• Master's degree or MBA preferred.
• Prior drug development, manufacturing, and clinical operations experience is a plus.
• Final title/scope of role will be commensurate with experience.
• Passion for patients, collaborative and effective leader.
• Knowledge of practical implications of Sarbanes-Oxley controls.
• Knowledge of continuous improvement methodologies and tools.
• Strong organizational and facilitation skills, with high degree of customer focus.
• Expertise and track record in manufacturing and supply chain execution and oversight.
• Extensive experience in supply chain planning, SAP ERP system, capacity modeling, supply network strategy and optimization.
• Expertise and have a proven track record in supply chain risk management.
• Solid knowledge of regulatory requirements, regulatory guidance, including pharmaceutical GMPs and ICH guidance.
• Current on Biopharma supply chain, manufacturing technologies, supplier network, CMO network, performance and capacity.
• Possesses understanding and application of principles, concepts, practices, and standards for DS and DP manufacturing in the biopharma industry.
• Strong communication, negotiation, and interpersonal skills.
• Strong analytical skills and ability to clearly communicate at tactical and strategic level with team and Sr Management.
• Ability to work in a dynamic and challenging environment.
• Some travel may be required.
• Must be able to work onsite, not a remote role.

Position Overview:

The Senior Director, Global Logistics, Warehousing and Trade Compliance is responsible for defining and executing the global strategy, operational leadership, and compliant storage and movement of materials supporting R&D, Clinical, and Commercial programs across Beam. This role provides end‑to‑end leadership across global logistics operations, warehousing networks, and trade compliance, ensuring reliable supply, regulatory adherence, and scalable infrastructure to support pipeline growth and commercialization.

This position reports to the Vice President, Supply Chain and serves as a key member of the Supply Chain Leadership team, partnering closely with Technical Operations, Quality, R&D, Finance, Legal, Procurement, Clinical Patient Supply and Commercial Patient Operations.

Responsibilities:

• Global Logistics: Provides operational and strategic leadership for all R&D, Clinical, and Commercial shipments. Serves as subject matter expert for ambient, low‑temperature, and ultra‑low‑temperature cold chain systems, including shipping systems qualification and lane validation, in support of CMC development and commercialization. Supports Commercial Patient Operations for Risto-cel Patient shipments.
• Warehousing: Leads internal warehouse operations and the global 3PL network supporting storage, inventory management, kitting, and production support for critical raw materials, drug substance, and drug product. Ensures inventory accuracy, material availability, and scalable warehouse capabilities aligned with clinical and commercial demand.
• Trade Compliance: Acts as the enterprise risk leader for global trade compliance, ensuring compliance with international, federal, and state import/export laws and regulations. Leads the development and governance of compliant, efficient trade processes across North America, Europe, and Asia‑Pacific regions, and serves as the primary interface with customs brokers, government agencies, and external auditors. Champions a culture of compliance while enabling business agility and uninterrupted supply. Supports Market Access team for any commercial trade or channel distribution aspects.
• Strategy & Leadership:
  • Develop and execute global logistics, warehousing, and trade compliance strategy to support R&D, clinical trials, and commercial operations.
  • Establish long‑term vision for a flexible, scalable global distribution and storage network, aligned with Beam’s growth and commercialization plans.
  • Serve as a senior leader influencing enterprise and site‑level supply chain strategies, including readiness for new product launches and expansion of cell and gene therapy programs.
  • Build, lead, and develop high‑performing teams, fostering a strong talent pipeline, culture of accountability, and continuous improvement mindset.
• Logistics Operations
  • Provide operational leadership for global distribution, including domestic and international shipments from internal sites and external partners.
  • Lead shipping operations supporting R&D, clinical, and commercial programs, ensuring on‑time, in‑full delivery and patient‑centric execution.
  • Own cold chain strategy and execution, including qualification, validation, monitoring, and continuous improvement of shipping lanes and systems.
  • Ensure logistics operations comply with GMP, GDP, EHS, product security, and data integrity requirements.

• Warehousing & Inventory Management:
  • Lead internal and external warehousing operations, including inventory control, materials management, kitting, and production support.
  • Ensure no disruption to production schedules while proactively identifying and mitigating supply risks.
  • Drive inventory optimization, accuracy, and visibility across the network using ERP and digital tools.

• Trade Compliance & Governance
  • Create, lead, and chair the Trade Compliance Committee, ensuring adherence to all applicable global import/export laws, regulations, and guidance.
  • Develop and maintain a robust global import/export compliance framework, including permits, licenses, valuation, duties, VAT, sanctions, HTS classification, country of origin, and applicable Tariffs/Free trade agreements.
  • Serve as primary respondent to regulatory agency inquiries; investigate issues, develop corrective strategies, and ensure timely, compliant responses.
  • Lead duty savings and optimization strategies in collaboration with Finance and Supply Chain, while maintaining full regulatory compliance.

• Performance, Financial & Operational Excellence
  • Establish and monitor KPIs across logistics, warehousing, and trade compliance with clear, data‑driven reporting.
  • Manage operating budgets, capital expenditures, and cost optimization initiatives.
  • Drive automation, digitalization, and process improvements to enhance efficiency, scalability, and compliance.
  • Champion lean principles, continuous improvement, and right‑first‑time execution across the organization.

• Stakeholder & External Engagement
  • Build and maintain strong partnerships with Legal, Finance, Clinical, Commercial, Quality, Manufacturing, Procurement, IT, and HR.
  • Represent the company with customs authorities, regulatory agencies, industry groups, and external counsel as required.
  • Participate in global forums to influence policy, standardization, and best practices across the supply chain network.

Qualifications:

• Bachelor’s degree in Business, Supply Chain, Engineering, Life Sciences, or related field; MBA or Master’s degree preferred.
• 18+ years of progressive experience in global logistics, warehousing, supply chain, and/or trade compliance within biotech, pharmaceutical, or other highly regulated environments.
• Proven senior leadership experience managing complex global networks of internal operations and external partners (CMOs, CDMOs, 3PLs).
• Working knowledge of global trade compliance regulations, including U.S. Customs and relevant international authorities; experience with permits, licenses, duties, VAT, sanctions, and duty savings strategies.
• Demonstrated expertise in pharmaceutical cold chain logistics (ambient, refrigerated, frozen, ultra-low temperature) across R&D, clinical, and commercial programs.
• Strong strategic and operational leadership skills, with the ability to influence cross-functional and matrixed stakeholders globally.
• Excellent analytical, communication, and decision-making skills in high-complexity environments.
• Financial acumen including budgeting, cost control, and KPI management.
• Experience with ERP systems (SAP preferred) and electronic Quality Management Systems.
• Relevant certifications or formal trade compliance training are preferred (e.g., Customs, Export Compliance, APICS, HAZMAT).

Travel / On-site Requirements:

Up to 20% travel required to support internal sites, external partners, and global supply chain initiatives.

Onsite requirements: Must be able to work onsite daily and willing to have a flexible schedule during peak times, which may include supporting critical operations outside of normal work hours, as needed.