Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X. 

About This Role  

Axsome Therapeutics is seeking a Clinical Monitoring Associate (CMA). Supporting the study Lead Clinical Research Associate (LCRA), the CMA provides administrative and operational support to assist effective site management and oversight of clinical monitoring for assigned protocols. With guidance from the LCRA, the CMA maintains study documentation and tracking tools and supports study activities from start-up through closeout. The CMA also assists with identifying and escalating quality issues related to monitoring activities and partners with the study team to document and implement action plans to address them. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

 Job Responsibilities and Duties include, but are not limited to, the following: 

• Support the LCRA team, in overseeing clinical monitoring operational execution of assigned clinical studies(s). 

• Assist the LCRA in compiling and analyzing monitoring metrics and study data, documenting results in the relevant trackers, and verifying monitoring compliance to support adequate oversight of clinical monitoring personnel. 

• Provide administrative support and tracking, which may include (but is not limited to) the following: 

• Confirm required CRA study training completion documentation. 

• Perform eTMF reconciliation activities (as assigned). 

• Maintain IP and freezer temperature log trackers. 

• File CRA meeting minutes and agendas in the eTMF. 

• Document oversight follow-up (e.g., track reasons for delayed report drafts and revisions). 

• Verify documents listed as collected in Monitoring Visit Reports (MVRs) are filed in the eTMF. 

• Review and maintain study site monitoring visit trackers. 

• May assist in the development/revision and/or provide input in the development of clinical trial related documents including but not limited to study tools, monitoring tools, presentations, meeting materials, case report forms, informed consents, timelines, clinical monitoring plans, site reference manuals, pharmacy manuals, laboratory manuals, protocols, and training materials. 

• May review clinical monitoring reports to ensure timely completion/finalization and identification of issues. 

• May participate in the Study Oversight meeting(s) with the Study team. 

• Review time sheets, expense reports and invoices. 

• Perform other work-related duties as assigned and under the direction of the Senior Director, Clinical Monitoring or Sr. LCRA. 

Requirements / Qualifications 

• BA/BS or equivalent degree required, preference for a background in a scientific discipline or related healthcare field. 

• Minimum of 1 year of clinical research experience in pharmaceutical, biotechnology, CRO industry. 

• 1 year of clinical monitoring and/or Clinical Trial Associate (CTA) experience preferred. 

• Excellent judgement, and problem-solving skills. 

• Strong organizational, communication, time management and multi-tasking skills. 

• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles. 

 Experience, Knowledge and Skills 

• Demonstrates core understanding of medical terminology and/or clinical trial activities. 

• Knowledge of clinical research operations, including interpretation and implementation of FDA regulations/ICH/GCP guidelines, required. 

• Experience in CNS preferred. 

• Ability to work on complex and/or multiple projects and exercise critical thinking with minimal supervision. 

• Solid interpersonal skills and communication skills (both written and oral). 

• Excellent team player, willingness and ability to fill functional gaps in a growing organization. 

• Ability to establish priorities, excellent sense of urgency and desire to collaborate (interpersonal, relationship management) with the study team, cross functional team members and external partners/vendors. 

• Self-motivated and adaptable to a dynamic environment. 

• Computer skills including proficiency in the use of Microsoft Office, CTMS, eTMF and eCRF platforms and organization tools. 

• Comfortable multi-tasking in a fast-paced company environment and able to adjust workload based upon changing priorities. 

• Willingness to travel up to 20%. 

 Salary & Benefits

The anticipated salary range for this role is $70,000 - $80,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Manager, Accounts Payable who will be responsible for managing the company’s financial obligations by processing invoices, managing and processing employee expense reports, issuing payments to vendors and expense report reimbursements, reconciling vendor accounts to ensure timely and accurate payments, and managing the 1099 process.  This position will be a trusted business partner across all functional departments within the company. The Manager Specialist, Accounts Payable will report directly to the Assistant Controller. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following: 

• Own and manage the accounts payable process ensuring timely and accurate invoice processing and payments, proper coding, reconcile vendor accounts, and manage vendor relationships
• Own and manage expense reports and corporate card process ensuring timely and accurate reimbursements, and compliance with company policies, procedures and IRS requirements for expense reimbursement
• Ensure compliance with IRS regulations by maintaining proper documentation and executing the annual 1099 reporting process for eligible vendors and filing the required 1099’s and the transmittal Form with the IRS by the mandated deadline
• Assist with monthly and quarterly financial close including preparing journal entries, preparing and reviewing general ledger account reconciliation and analysis, review of financial statements 10-Q, 10-K
• Support process reviews for automation, system enhancements, and implementation including ERP, FP&A tools, procure to pay, order to cash systems
• Collaborate with departments, support internal and external auditor quarterly reviews and annual audits by providing necessary documentation related to accounts payable and 1099 filings and responding to audit inquiries
• Participate in the development of control evidence expectations, detailed SOX testing plans and reviewing test guidance/scripts for completeness, and accuracy, and SOX walkthroughs 

Requirements / Qualifications 

• Minimum of an associate's degree in accounting, finance or business
• 10+ years of experience in a full-cycle accounts payable role
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience, Knowledge and Skills 

• Proven experience in a full-cycle accounts payable role, with direct involvement in the 1099 process
• Strong knowledge of IRS regulations related to 1099 reporting
• Excellent attention to detail and a high degree of accuracy
• Possess a problem-solving mindset with demonstrated “lean-forward” approach and the ability to think critically
• Strong planning and organization skills, attention to detail, execution, and follow-through 

Salary & Benefits  

The anticipated salary range for this role is $85,000 - $110,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role 

Axsome Therapeutics is seeking a Specialist, Quality Assurance to focus on ensuring compliance with Good Manufacturing Practices (GMP) with all work performed. The Specialist, Quality Assurance will provide the Quality Assurance team oversight of external manufacturing activities to ensure consistent compliance with company procedures, regulations, and industry expectations. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following: 

• Review executed batch production records for completeness, GDP and ALCOA requirements
• Communicate and resolve discrepancies with third-party CMOs
• Perform release of all manufactured, packaged and tested materials (including but not limited to raw materials, intermediates and drug products)
• Ensure timely escalation to management of all applicable incidents
• Review test and stability data ensuring data accuracy, conformance to test procedures, specifications, and documentation standards
• Initiate and track quality events (deviations, change controls, CAPAs) in Axsome’s eQMS through closure
• Work collaboratively with internal departments to respond to and resolve deviations and OOSs
• Provide support in the review and approval of cGMP-controlled documents such as master batch records, test methods, and specifications
• Provide support in the review of change controls related to manufacturing, analytical test methods, and specifications to meet cGMP and internal standards
• Support the annual product review process
• Provide QA support for process validations including reviewing protocols and reports
• Contribute to the refinement and ongoing improvement of manufacturing processes and documentation at various CMO locations
• Write and review Standard Operating Procedures, as needed
• Support the development, implementation, and improvement of corporate quality management systems that support late phase clinical and commercial programs.
• Support regulatory agency inspections as needed
• Support the development and reporting of site Quality Metrics 

Requirements / Qualifications 

• Bachelor’s degree required with a preference within a scientific discipline
• At minimum 2 years of relevant Quality Control or Quality Assurance experience in a GMP- regulated commercial environment  
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience and Knowledge 

• Proficient knowledge of GMP regulations and guidance documents
• At least 1 year experience reviewing manufacturing batch records is preferred
• Experience working in Quality Assurance Operations with a strong focus on Batch Record Review and Shop Floor support
• Experience supporting clinical manufacturing operations is a plus
• Strong attention to detail 
• Excellent interpersonal and communication skills (both written and verbal)
• Proven ability to multitask projects of varying complexity 

Salary & Benefits 

The anticipated salary range for this role is $80,000 - $93,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking an Associate Director/Director, Technical Operations – Drug Substance (Small Molecules) to provide technical leadership across the development and commercial lifecycle of small‑molecule drug substance programs. This role is responsible for supporting and overseeing drug substance manufacturing activities, including technology transfer, process validation, continued process verification (CPV), and post‑approval process changes at internal and external manufacturing sites.

The successful candidate will serve as a key technical leader within CMC, partnering closely with external CDMOs and internal cross‑functional teams (QA, QC, Regulatory, R&D, and Supply Chain) to ensure robust, compliant, and efficient manufacturing operations. This position reports into senior CMC leadership and plays a critical role in ensuring technical excellence, regulatory compliance, and continuous improvement across Axsome’s drug substance portfolio.

This role is based at Axsome’s HQ in New York City with an on‑site requirement of at least three days per week. Fully remote candidates cannot be considered.

Job Responsibilities and Duties include, but are not limited to, the following:

• Lead and support day‑to‑day technical operations for commercial drug substance manufacturing in compliance with cGMP, FDA, EMA, and ICH guidelines
• Prepare, review, and approve technology transfer documentation, validation protocols, and final reports for new and existing products
• Provide technical leadership for process performance qualification (PPQ), scale‑up activities, and manufacturing readiness at internal and external sites
• Develop, review, and maintain Continued Process Verification (CPV) programs, including statistical trending, control charting, and process capability analysis
• Apply advanced statistical tools to assess process capability, identify trends, and drive data‑driven continuous improvement initiatives
• Lead and support investigations related to OOS/OOT results, deviations, and non‑conformances, including root cause analysis and CAPA implementation
• Perform risk assessments and develop mitigation strategies for process changes, equipment modifications, and supplier or raw material changes
• Support drug substance process development, optimization, troubleshooting, and technical transfer for mid‑ to late‑stage development programs
• Author and review Module 3 sections of regulatory submissions, including post‑approval changes related to scale, equipment, materials, and manufacturing processes
• Provide technical oversight and management of external CDMOs, ensuring alignment with quality, regulatory, and project timeline expectations
• Collaborate with QA, QC, Regulatory Affairs, R&D, and Supply Chain to resolve technical issues and ensure operational excellence
• Initiate and approve change controls, SOPs, and supporting GMP documentation as required
• Maintain current technical knowledge by evaluating and implementing new technologies, industry best practices, and regulatory expectations
• Design and lead technical investigations, interpret complex data sets, and provide clear recommendations for troubleshooting and next steps

Requirements / Qualifications

• BS, MS, or PhD in Chemical Engineering, Chemistry, or a related technical discipline
• MS or PhD with 6–8+ years of directly related experience in pharmaceutical drug substance manufacturing, MSAT, or technical services; or Bachelor’s degree with 10+ years of directly related experience in small‑molecule drug substance manufacturing or technical operation 
• Demonstrated hands‑on experience supporting commercial drug substance manufacturing and process validation activities
• Ability to work on‑site Monday, Tuesday, and Thursday at Axsome’s New York City headquarters. 
• Willingness to travel periodically as required

Experience, Knowledge and Skills

• Advanced knowledge of small‑molecule drug substance processing, including technology transfer, commercial manufacturing, and unit operations
• Hands‑on experience with PPQ, CPV, and post‑approval change management is required; pre‑approval process development experience is highly preferred
• Deep technical understanding of CPPs, CQAs, IPCs, and drug substance process transfer fundamentals
• Solid‑state chemistry and particle engineering experience is strongly preferred
• Experience supporting FDA and global regulatory submissions, including post‑approval change applications
• Detailed understanding of drug substance manufacturing floor operations and practical execution of cGMP requirements
• Proficiency with statistical software and application of statistical methods for process monitoring, trending, and improvement
• Experience with unit operation modeling and process simulation tools is a plus
• Strong working knowledge of cGMP regulations, FDA expectations, and SOP governance
• Demonstrated ability to lead technical discussions, influence cross‑functional stakeholders, and manage external manufacturing partners

Salary and Benefits:

The anticipated salary range for this role is $175,000 - $215,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role 

Axsome Therapeutics is seeking a CMC Project Manager with experience in pharmaceutical development to be a key contributor within the CMC department to drive operational execution and ensure alignment with strategic objectives. The role will report into the Senior Director of CMC Project Management.   

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following:

• Manage day-to-day planning, coordination and execution of CMC project activities that may include early, late, and lifecycle stages, ensuring alignment within CMC project teams and cross-functionally
• Interface with and manage drug substance and drug product CDMOs involved with development activities related to formulations, manufacturing, analytical testing, packaging and labeling of investigational products
• Leverage established project management tools to track project execution, milestones, risks, and long-range planning to ensure appropriate communication to team members and management
• Lead internal team meetings and work collaboratively with CMC team leaders and other functional area team members to track critical operational aspects of the projects
• Participate as a key member of the CMC and internal project teams to develop and implement strategy for individual projects
• Contribute to the implementation and enhancement of project management tools, templates, dashboards, and operating mechanisms
• Participate in further developing processes, standards, and tools to enhance productivity and effectiveness toward meeting CMC team strategic goals
• Assist in preparation of CMC written documents for regulatory submissions (e.g. INDs, CTAs, NDA Module 3)

Requirements / Qualifications

• Bachelor’s/Master’s/PhD degree in a scientific/engineering discipline required
• At least 7 years of experience working within biopharmaceutical R&D or Technical Operations
• Strong understanding of end-to-end drug product development and CMC processes, and solid knowledge of GMP and regulatory requirements
• Hands-on experience in one or more drug product development areas (e.g. formulations, manufacturing, analytical)
• Demonstrated success in leading cross-functional teams in a matrixed environment, proficiency with project planning and reporting, and risk management
• Excellent written and verbal communication and interpersonal skills with good problem-solving ability; experienced in presenting to senior stakeholders
• Willingness to travel periodically as needed
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Certified project management training (PMP) a plus, preferred but not required
• Experience with project management software or other presentation/reporting tools preferred
• Solid understanding of FDA regulatory guidance, ICH guidelines and requirements of NDA and IND documentation
• Prior experience interfacing with and managing drug substance and drug product CDMOs preferred
• Technical experience with solid oral dosage form development preferred but not required
• Exceptional organizational skills with the ability to multi-task and prioritize workload based upon changing priorities

Salary and Benefits:

The anticipated salary range for this role is $125,000 - $155,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X. 

  
About This Role 

Axsome Therapeutics is seeking an intern to support the Information Technology team. This individual will be responsible for assisting members of the IT team with a variety of day-to-day tasks, and ongoing projects.  

The IT Marketing intern will report directly to the Senior Business Analyst, IT Marketing and will work cross-functionally. This role will work closely with IT and Marketing teams, supporting campaign work for multiple brands while assisting with IT-focused Salesforce Marketing Cloud administration and maintenance.  

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following: 

• Support the team with day-to-day tasks related to SFMC email campaign planning and execution  
• Assist with campaign and platform performance reporting 
• Help maintain shared SFMC assets such as templates, content blocks and technical documentation. 
• Support documentation, change tracking and basic governance processes 
• Assist in testing email links, forms and campaigns 
• Identify and troubleshoot HTML issues  
• Partner with IT and marketing teams to translate business needs into creative, effective technology-enabled marketing strategies 
• Additional responsibilities as assigned 

Requirements / Qualifications 

• Actively enrolled with a minimum 3.0 GPA in an undergraduate or graduate program with a focus  on Information Technology, Information Systems, Computer Science or a related field 
• Interest in CRM systems, platform administration, and marketing technology  
• Basic understanding of digital marketing concepts (email, automation, customer journeys)   
• A proactive, creative, and entrepreneurial approach to work   
• Interest and/or experience in CNS diseases 
• Excellent oral and written communication skills  
• Demonstrates strong attention to detail   
• Proficient in Microsoft Office Suite (Excel, Word, PowerPoint) 
• Organizational and critical thinking skills 
• Strong interpersonal skills and the ability to work well with technical and non-technical stakeholders 
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience and Knowledge 

• Basic knowledge of HTML  
• Familiarity with SQL or database concepts  
• Exposure to Salesforce Marketing Cloud or Salesforce ecosystem tools a plus  
• Salesforce Trailhead coursework a plus  
• Interest in Pharmaceutical/Life Sciences industry a plus 
• Accomplished background demonstrating teamwork, creativity, leadership, good judgement, and delivering results 

Additional Details

The anticipated hourly rate for this role is $18-$25/hour. The salary offer will be based on a variety of factors, including experience, qualifications, and internal equity. 

This is a full-time and temporary role beginning in June and concluding in August. Final dates will be confirmed this spring. Successful candidates will be compensated at an hourly rate for the duration of the internship. Interns will work a maximum of 40 hours a week. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X. 

  
About This Role 

Axsome Therapeutics is seeking an intern to support the Pharmacovigilance team. This individual will be responsible for assisting members of the Pharmacovigilance team with a variety of day-to-day tasks, and ongoing projects.   

The Pharmacovigilance Intern will report directly to the Senior Director, PV Operations and will work cross-functionally.  

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following: 

• Perform drug information research and /or presentations to extend the understanding of Axsome products  
• Research and understand the disease, symptoms, and treatment of various CNS disorders
• Extensive research of drug addiction vs abuse
• Participate in data analysis in MedDRA coding for ICSR assessment and some potential safety topics analysis for evaluation
• Understand the process of vendor management
• Participate in literature review
• Review applicable Health Authority regulations and ICH guidelines to optimize current Axsome practices aligning with regulatory requirements and industry standards
• Opportunity to initiate or be assigned to pharmacovigilance projects 
• Additional responsibilities as assigned 

Requirements / Qualifications 

• Actively enrolled with a minimum 3.0 GPA in an undergraduate or graduate program with a focus on a medical field e.g., nursing, neuroscience, psychology, psychiatry, biology, pharmacy, etc.  
• A proactive, creative, and entrepreneurial approach to work   
• Interest and/or experience in CNS diseases 
• Excellent oral and written communication skills  
• Demonstrates strong attention to detail   
• Proficient in Microsoft Office Suite (Excel, Word, PowerPoint) 
• Organizational and critical thinking skills 
• Strong interpersonal skills and the ability to work well in a team environment 
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience and Knowledge 

• Experience and knowledge in literature screening for potential literature case or MOA of potential drug adverse reaction 
• Interest in Pharmaceutical/Life Sciences industry a plus
• Accomplished background demonstrating teamwork, creativity, leadership, good judgement, and delivering results 

Additional Details

The anticipated hourly rate for this role is $18-$25/hour. The salary offer will be based on a variety of factors, including experience, qualifications, and internal equity. 

This is a full-time and temporary role beginning in June and concluding in August. Final dates will be confirmed this spring. Successful candidates will be compensated at an hourly rate for the duration of the internship. Interns will work a maximum of 40 hours a week. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X. 

About This Role 

Axsome Therapeutics is seeking a Manager, Data Management to be responsible for conducting and overseeing all data management aspects for assigned clinical program(s) in compliance with ICH GCP, regulatory guidelines/standards and applicable SOPs. Tasks include collaborating cross-functionally with study teams, providing DM expertise and conducting all data management activities, overseeing vendors, timelines, costs, resources, and key project deliverables.   

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

 Job Responsibilities and Duties include, but are not limited to, the following: 

• Data management oversight of multiple clinical development programs in addition to serving as the lead clinical data manager on designated programs as needed  

• Responsible for data related vendor selection and oversight activities across multiple clinical development programs  

• Oversee the planning and management of Data Management costs and timelines  

• Represent data management function on the clinical and cross-functional team meetings ensuring aligned expectations between all parties, including outside vendors.  

• Ensure achievement of major data management deliverables and milestones in coordination with other functions including Clinical Operations, Safety, Statistics, etc.  

• Responsible for drafting safety and other customized data listings/metrics/reports to drive activities such as medical reviews, clinical reviews and risk-based monitoring  

• Participate and represent data management function in during audits and inspections as requested.  

• Author, review, and revise Standard Operating Procedures (SOPs)  

• Draft/review Data Management Plans, data entry guidelines, data management reports and other documents   

• Lead the development and user acceptance testing of Case Report Forms (CRFs) and edit check specifications per protocol, across the lifecycle of the study   

• Manage external data transfers, reconciliations, and system integrations  

• Lead the process of cleaning databases by performing a review of clinical trial data through EDC or data listings  

• Generate queries to appropriate internal or external personnel (e.g. - investigational sites, vendors, Clinical Research Associates) to resolve problematic data identified during every aspect of the data management process  

• Review responses to queries for appropriateness and resolution to ensure high data quality  

• Train team members on Axsome procedures, study specific handling and management of Data Management systems   

• May also act to supervise and mentor data management staff  

• Ensure archival of all Data Management Trial Master File (TMF) documents 

 Requirements / Qualifications 

• Bachelor’s degree required. Preference to candidates with a scientific background (RN, MS, MD, PharmD, PhD or similar)  

• Minimum of 4 - 7 years data management experience in a biotech/pharmaceutical company or clinical research organization (CRO)  

• Thorough understanding of FDA, GCP and ICH guidelines  

• Strong knowledge of EDC and/or systems design (i.e., Merative Zelta (IBM Clinical), Veeva, Medrio, Rave, etc.), IRT/IWRS and data warehouse technologies as applied to clinical trials  

• Strong working knowledge of (e)CRF design and data management functions/activities as applied to standards library development and maintenance  

• Good working knowledge of CDISC standards and experience implementing standards preferred  

• Advanced knowledge of Excel  

• Good working knowledge of general statistical programming processes and practices. Advanced knowledge of medical terminology, medical coding, laboratory reference ranges, and clinical procedures 

• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

 Experience, Knowledge and Skills 

• Exhibits initiative, strong problem solving and leadership skills  

• Ability to handle multiple programs simultaneously with strong project management capabilities  

• Comfortable multi-tasking in a fast-paced small company environment and able to adjust workload based upon changing priorities  

• Excellent team player: willingness and ability to fill functional gaps in a small but growing organization  

• Preference to energetic candidates with a desire to think “outside the box”   

• Strong attention to detail and excellent organization skills  

• Strong interpersonal skills and communication skills (both written and oral)  

• Embody a culture of continual improvement and innovation; promote knowledge sharing 

 Salary & Benefits 

The anticipated salary range for this role is $125,000 - $140,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role 

Axsome Therapeutics is seeking an Associate Director/Director, Regulatory Affairs. The role is responsible for managing assigned regulatory activities for the development and commercialization of Axsome’s product candidates. The right candidate will have had prior experience in independently providing regulatory guidance to investigational and commercial products under oversight provided by the department head when needed. The Associate Director/Director is responsible for mentoring associates as appropriate. This role reports directly to the VP, Regulatory Affairs.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following:

• Participate in regulatory agency interactions
• Manage preparations for agency meetings, communications, and submissions
• Author and review regulatory submissions including IND, NDA, and ex-US filings
• Contribute to regulatory strategy development and planning
• Assist and provide guidance for regulatory inspection readiness activities
• Provides analysis of regulatory guidance documents and regulations to management team
• Create, manage, measure, and report timelines for milestone deliverables
• Participate in the development, review, and implementation of departmental SOPs, initiatives and processes
• Additional responsibilities as assigned

Requirements / Qualifications

• Bachelor’s degree required. Preference for candidates with an scientific advanced scientific degree
• 7-10 years of relevant Regulatory Affairs experience
• Proficiency in FDA electronic gateway submissions
• Broad understanding of eCTD requirements
• Willingness to travel as needed
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Prior NDA and MAA filing experience
• Prior CNS experience preferred but, not required
• Experience in translating regulatory strategy into actionable plans
• Established knowledge of regulatory guidelines and regulations (US and international)
• Regulatory experience supporting both development projects and marketed products preferred
• Knowledge of clinical research operations, including interpretation and implementation of FDA regulations/ICH/GCP guidelines, is preferred
• Ability to work on complex or multiple projects and exercise independent judgment within generally defined practices and policies lead to obtaining results
• Strong attention to detail and excellent organization skills
• Exceptional communication skills (written and verbal) as evidenced by a demonstrated ability to prepare complex documents and submissions and to give presentations
• Strong interpersonal skills
• Ability to problem solve, delegate appropriate tasks and/or develop junior team members
• Strong leadership skills, self-motivated, adaptable to a dynamic environment
• Comfortable multi-tasking in a fast-paced small company environment and able to adjust workload based upon changing priorities

Salary & Benefits

The anticipated salary range for this role is $160,000 - $215,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role  

Axsome Therapeutics is seeking an Associate Director, Patient Services to lead the establishment and growth of a new Patient Services Hub. This role will work closely with the Director, Patient Services for developing, implementing, and overseeing all aspects of the Hub's operations, ensuring efficient and seamless patient access to therapies and support services. This role requires a strong leader to build and manage the hub team, foster collaborative relationships, and drive continuous improvement within a fast-paced environment. This role will have close collaboration among, and provide ad hoc support to, Field Access and Patient Service functions within the Market Access team, as related to the HUB. This role reports directly to the Director, Patient Services.   

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following: 

Requirements / Qualifications 

• Support in the design, development, and implementation of the Patient Services Hub, including workflow creation, process optimization, and technology integration. 

• Develop and implement strategies to continually enhance the patient & provider experience and address patient needs effectively through regular intervals of bench marking and ATU research. 

• Ensure compliance with all applicable regulatory requirements and patient information privacy policies, including HIPAA regulations. 

• Act as the primary point of contact for the HUB administrator and operations for Patient Services, ensuring high standards of service delivery, and maintaining optimal service levels. 

• Develop and monitor key performance metrics to assess program effectiveness and identify areas for improvement. 

• Analyze program processes and provide recommendations for improving efficiency and reducing costs without compromising quality of care. 

• Plan and execute training programs for Hub staff and internal teams on new procedures, systems, and patient support strategies. 

• Develop and implement metrics and KPIs to measure Hub performance, patient satisfaction, and program effectiveness. 

• Monitor and analyze Hub performance data, identify areas for improvement, and implement corrective actions as needed. 

• Collaborate with Field Reimbursement Managers and Market Access leadership on program needs across the portfolio. 

• Respond to and resolve broader and complex escalated issues. 

• In partnership with Director, develop and manage overall program improvements and optimizations across the portfolio. 
• Manage multiple projects in a fast-paced, deadline-driven, entrepreneurial environment, adapting to change as needed. 

Requirements / Qualifications 

• Bachelor’s Degree and 7+ years of experience in Patient Service HUB management within the biotech industry. 

• Relevant experience in leading patient support (HUB) programs and leading complex product launches within the patient support space 

• Experience in managing complex and dynamic projects, programs, and teams across a fast paced  
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience, Knowledge and Skills 

• Analytical mindset and experience directing and managing activities that are critical to both the home office and field sales. 

• Strong understanding of industry trends in the pharmaceutical patient services landscape. 

• A problem-solving mindset with demonstrated “lean-forward” approach and ability to think critically. 

• Previous product launch experience, preferably in the CNS space. 
• Ability to influence decision makers and educate variety of internal audiences on complex concepts 

Salary & Benefits (HR will complete) 

The anticipated salary range for this role is $155,000 - $185,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Manager/Senior Manager, Regulatory Operations.  Level will be commensurate with prior Regulatory Operations experience. The role is responsible for managing regulatory operations necessary to ensure the successful preparation and filing of regulatory submissions for multiple product candidates. The right candidate will have knowledge of the regulatory requirements for electronic submissions and prior experience with publishing of regulatory submission, electronic document management, and regulatory information management (RIM) systems. This role reports to the Executive Director, Regulatory Affairs.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.

JOB RESPONSIBILITIES

• Publish electronic submissions: compile and generate submission packages, validate submission, and address any warnings or errors before submission
• Coordinate internal publishing activities
• Finalize regulatory documents for electronic submission by verifying document completeness and applying formatting standards
• Provide training and support for publishing and electronic document management systems
• Track submission statuses and maintain logs of submission sequences, dates, and acknowledgments
• Archive health authority communications and submissions, including storing published packages and validation reports
• Work closely with document authors, reviewers, and regulatory leads to ensure timely and high quality submission
• Manage vendors in support of electronic publishing and other aspects of regulatory operations
• Additional responsibilities as assigned

QUALIFICATIONS

• Bachelor’s degree required
• 5 years or more of Regulatory Operations experience
• Understanding of eCTD requirements, FDA electronic gateway submissions, and FDA guidance documents
• Operational experience supporting investigational and/or marketed products (INDs/CTAs, NDAs/MAAs)
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Prior experience with regulatory document publishing and submission
• Prior experience with regulatory information management systems
• Proficiency with Microsoft Office Suite and Adobe Acrobat
• Strong attention to detail and excellent organization skills
• Exceptional time-management skills
• Strong interpersonal skills
• Comfortable multi-tasking in a fast-paced small company environment and able to adjust workload based upon changing priorities

Salary and Benefits:

The anticipated salary range for this role is $120,000 - $150,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking an Associate Director/Director, Long Term Care Marketing. This role is responsible for developing and executing strategy and tactics for the launch of Alzheimer’s Disease Agitation in key channels such as LTC. The Marketer will develop and execute both personal and non-personal promotion tactical plans in line with brand strategies. This role will collaborate cross functionally with Market Access, Regional Marketing, Patient Marketing, Patient Support Services, Sales, Market Access, Data & Market Analytics, as well as other internal and external partners. Deliverables to include POA development, brand communications, cohesive messaging and content tailored for specific audiences, etc. This individual reports to the Executive Director, Marketing, Alzheimer’s Disease.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following:

• Work cross-functionally to adapt the launch strategy for Alzheimer’s Disease Agitation to maximize potential in key channels
• Partner with Market Access, Market Insights, Medical Affairs, and Regional Marketing to develop and align tailored marketing messages, tactics, and resources for each channel of business
• Lead Legal / Regulatory / Medical review of all channel-specific materials
• Lead strategy for national society interactions and congress meetings by channel
• Collaborate with multiple external agencies including creative, digital, media, and P2P
• Identify appropriate measurements & ROI, and develop comprehensive reporting to evaluate effectiveness of specific channel promotion initiatives
• Identify strategic market opportunities and make recommendations to enhance brand penetration into key channels
• Manage timelines and budgets in accordance with brand plan

Requirements / Qualifications

• BA or BS, advanced degree preferred
• 8-10 years of experience in the pharmaceutical industry including a minimum of 6 years in marketing
• Experience in leading the successful development and creation of LTC marketing content
• Strong personal drive, highly collaborative, problem solver that exhibits strategic insight and innovative agility
• Ability to meet multiple deadlines across a variety of projects with a high degree of accuracy and efficiency
• Demonstrated ability to achieve results in a highly matrixed organization
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience and Knowledge:

• Demonstrated proactive, creative and entrepreneurial approach
• CNS disease experience and/or launch experience strongly preferred
• Strong project and process management skills, including competency in agency management and budget management
• Strong digital marketing aptitude
• Strong interpersonal and presentation skills

Salary and Benefits:

The anticipated salary range for this role is $170,000 - $225,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role  

Axsome Therapeutics is seeking a Manager, Marketing Operations & Speaker Bureau Management to drive the day-to-day execution behind our Psych professional education programs and support key field operations. Reporting to the Director, Marketing and Professional Operations, this position will be directly involved in all aspects of speaker bureau operations including logistics, contracting and vendor management. In addition, this role will directly manage core field-facing operational processes like credentialing, promotional resource management, and commercial field updates. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.   

Job Responsibilities and Duties include, but are not limited to, the following: 

Psych Speaker Bureau & Professional Education  

• Support the day-to-day operations of the Psychiatric Speaker Bureau 

• Manage speaker onboarding, training schedules, contracting steps, and roster updates 

• Coordinate program logistics, event tracking, and reporting 

• Work with Compliance, Medical, and Marketing to ensure materials and processes are accurate and approved 
• Track costs and help monitor budget usage 

Field Execution and Marketing Operations Support 

• Serve as the contact for field credentialing support 

• Oversee inventory, shipping, and distribution of field materials 

• Manage vendor coordination for print items, supplies, and field kits 

• Track costs and help monitor budget usage 

• Support updates to sales tools and field-facing resource platforms 

• Organize and distribute internal updates across the portfolio 

Requirements / Qualifications 

• Bachelor’s degree in Marketing, Business, Communications, or related field

• 5+ years of experience in commercial operations, marketing operations, event coordination, speaker bureau, or similar role 
• Strong project management and organization skills 

Experience and Knowledge 

• Comfort working with multiple stakeholders and tight timelines 

• Understanding of pharma compliance and HCP engagement 

• Experience with Veeva or similar systems is helpful 
• Excellent communication and follow-through 

Salary & Benefits  

The anticipated salary range for this role is $110,000 - $120,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Director/Senior Director, Field Medical Enablement. This role is responsible for creating and delivering training programs that enhance both scientific knowledge and key professional skills for field medical teams. Additionally, the Director/Senior Director, Field Medical Enablement will collaborate with internal Medical Affairs personnel to plan and manage the development of scientific slide decks and engagement tools used by Field Medical Teams. This role will require coordination and alignment across multiple functions in Medical Affairs. Reporting to the Executive Director of Field Medical, this individual will serve as a strategic member of the Field Medical Leadership Team, ensuring the success and adaptability of the Field Medical teams for the future.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following:

Learning and Development

• Accountable for developing, refreshing and maintaining functional onboarding training curricula for Medical Affairs
• Work with Field Medical Leadership to develop, and lead the implementation of scientific training content and curricula for multiple field Medical Teams, utilizing agency partners and/or internal resources as appropriate
• Ensure adult learning principles and industry best practices are incorporated into training curricula.
• Conduct needs assessments, identify knowledge gaps, and tailor training solutions to support Field Medical professional growth and skills development.
• Drive adoption of innovative training methods and learning technologies to enhance field capabilities.
• Collaborate with Medical Affairs leaders to strategically align training programs fit to ensure fluency and

Field Engagement Tools

• Working with Field Medical Teams, Medical Directors and Scientific Communications, oversee annual plans for field tool creation and deployment
• Stay informed on advancements, evolving standards and the latest innovations in Field Medical engagement tools
• Responsible for upfront project management for third-party vendors/agencies engaged in the development of training materials and MSL field tools such as slide decks
• Define project scopes, set timelines, monitor deliverables, and manage budgets to ensure on-time, high-quality execution.
• Organize and ensure appropriate training of field tools

Requirements / Qualifications

• Advanced degree in a scientific or healthcare field.
• 10 years’ experience in Medical Affairs with a minimum of 3 years of experience as a MSL and/or field medical training/resource lead
• Experience in Psychiatry / Neurology strongly preferred
• Demonstrated expertise in adult learning theory, training program development, and operational best practices.
• Proven ability to manage cross-functional projects and collaborate effectively with both internal stakeholders and external partners.
• 30% business travel required
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Strategic thinking, problem-solving, scientific storytelling, and innovation.
• Strong analytical, organizational, and communication skills; experience with budgetary and resource stewardship is a plus.
• Project management and organizational agility, especially across dispersed teams and multiple priorities.
• Interpersonal influence and ability to provide coaching and professional development guidance.
• Familiarity with compliance frameworks and effectiveness of measurement in medical affairs.
• Experience with resource allocation and vendor and budget management.
• Experience working with learning management systems, project management tools, and vendor oversight is strongly preferred.

Salary and Benefits:

The anticipated salary range for this role is $200,000 - $235,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Senior Manager, Field Reimbursement Analytics and Field Effectiveness (Neurology) to lead the operational infrastructure supporting our internalized Field Reimbursement Manager (FRM) team and Neurology sales operations. This role is critical to managing the transition from external vendor to internal operations while scaling support for increasing patient service volumes and complex incentive compensation requirements. The position requires deep technical expertise in data engineering, automation, and operational analytics to support field targeting, performance reporting, and incentive compensation administration. The ideal candidate combines strong programming and analytical capabilities with excellent communication skills to translate complex technical concepts into actionable insights for field leadership and internal stakeholders. This role reports directly to the Director of Field Effectiveness.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following:

• Manage targeting strategies and ongoing alignment changes for the FRM team, including weekly and monthly call plan updates, territory realignments and incentive compensation coordination
• Serve as primary liaison between FRM leadership, Commercial Operations, Market Access, and external vendors
• Build and maintain automated data infrastructure integrating CRM, claims, and PA submission/approval data to enable real-time patient service analytics and market access intelligence
• Create dashboards and reports for the FRM team showing PA initiation rates, submission volumes, approval rates by territory, market access trends, and field execution metrics
• Identify relevant KPIs and collaborate with field leadership to implement analytics that enable effective performance management and opportunity identification
• Develop advanced analytics linking PA rates, approval rates, and FRM activity patterns by geography to identify market access barriers and optimization opportunities
• Handle ad hoc sales analytics, reporting, and incentive compensation requests for Neuro sales teams
• Create targeted analyses to identify field execution opportunities based on CRM engagement data and secondary data sources (IQVIA/Symphony). Support continuous improvement of sales operations processes across the Neuro portfolio
• Support Sales leadership in the organization and coordination of National Sales Meetings, Manager Meetings, and Period-of-Action (POA) planning sessions
• Prepare executive-level presentations translating complex analytical findings into clear business recommendations
• Additional responsibilities as assigned

Requirements / Qualifications

• BS/MS/PhD in Engineering, Physics, Applied Physics, Statistics, Computer Science, or related quantitative field strongly preferred
• A minimum of 6 years of sales operations experience in the pharmaceutical or biotech industry (which may include work as a consultant or supplier to the industry)
• Expert-level SQL skills for complex queries, joins, and data manipulation. Advanced proficiency in Python (pandas, numpy) or R for data analysis and automation
• Advanced Excel capabilities including VBA/macros, Power Query, Power Pivot, and complex formula design
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Excellent written and verbal communication skills with ability to translate complex technical concepts into clear business insights for all organizational levels
• Experience in Sales Force Design, Alignment, Targeting, Call Planning, and Incentive Compensation
• Experience in omnichannel planning and supporting Veeva CRM applications

Salary and Benefits:

The anticipated salary range for this role is $140,000 - $160,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role  

Axsome Therapeutics is seeking a highly collaborative Medical Writer to draft, edit and submit high quality, medically accurate documents including protocols and clinical study reports. This is a key position within the Clinical Development Group with ample opportunity to make real impact. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following:  

• Interpret, analyze, and synthesize complex clinical data and develop high-quality strategic scientific documents including protocols, amendments, agency briefing books, clinical study reports, and other documents in support of Clinical Development programs    

• Attend strategic meetings as applicable 

• Closely collaborate with, and apply strategic direction from, project leads and biostatisticians to manage and prioritize assignments and ensure deliverables are completed per time and quality goals 

• Develop documents for assigned programs in compliance with company standard operating procedures (SOPs) 

• Participate in developing timelines, managing review/approval workflows, and QC/publication readiness 

• Lead cross-functional teams to ensure team-wide agreement on documents content 

• Oversee outsourced medical writings projects and the associated vendor(s), as applicable 

• Ensure compliance and accountability for all regulatory documents prepared by the company 

Requirements / Qualifications  

• Advanced scientific or clinical degree (MD, PhD, or PharmD) required and a minimum of 6 years of relevant experience 

• Previous experience with preparation and QC of clinical regulatory documents: Protocols, IBs, CSRs, Module 2 Summary Documents, Clinical Overviews and Agency Briefing Document 

• A strong working knowledge of pharmaceutical drug development and GxP principles 

• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

 Experience, Knowledge and Skills  

• Highly knowledgeable in psychiatric and/or neurological disease areas is a plus 

• Track record of developing high-quality scientific documents 

• Ability to interpret, analyze, and synthesize complex clinical data into compelling and easily understood documents 

• Familiarity with the preparation of Statistical Analysis Plans and document data mapping 

• Experience with programmed outputs of tables, figures and listings for analysis and communication of clinical data 

• Ability to work collaboratively with and coordinate the efforts of team members to resolve comments and complete deliverables 

• Excellent interpersonal skills and judgement that facilitates working with cross-functional executive leadership and maintaining the security of proprietary information 

• Ability to manage/prioritize multiple projects under general supervision while working in a fast-paced environment 

• Flexibility for adapting to rapidly changing deadlines and priorities 

• Must be extremely detail oriented 

• Able to self-manage effort to maintain alignment with strategy and corporate goals 

Salary & Benefits 

The anticipated salary range for this role is $140,000 - $175,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X. 

 About This Role 

Axsome Therapeutics is seeking a Senior Manager, Digital Centric Commercialization (DCC) Analytics and Operations to lead the evolution of our Next Best Action capabilities and manage exponentially increased complexity from our multi-brand, multi-team commercial portfolio. This highly technical role requires expertise in machine learning, optimization algorithms, and commercial analytics to transition DCC Intelligence from static, single-model suggestions to a continuous test-and-learn framework. The position is critical for implementing multi-team optimization that allocates promotional activities across overlapping sales forces to maximize profitability while avoiding customer fatigue. 

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

 Job Responsibilities and Duties include, but are not limited to, the following: 

• Build linear optimization engine that allocates promotional calls across multiple teams to overlapping HCP targets.  

• Develop objective functions maximizing expected revenue while incorporating constraints including call capacity, contact limits, customer fatigue thresholds, and strategic imperatives; responsible for managing this process on a quarterly basis 

• Design and implement continuous test-and-learn framework for Next Best Action (NBA) suggestions that include business rules, ML models, and hybrid approaches 

• Design comprehensive DCC performance dashboard with leading and lagging indicators 

• Develop suite of advanced predictive models including HCP propensity to prescribe, churn risk etc. 

• Create ad hoc analyses to identify field execution opportunities and commercial optimization insights based on CRM engagement data, promotional response patterns, and secondary data sources (IQVIA/Symphony) 

• Support Sales leadership in the organization and coordination of National Sales Meetings, Manager Meetings, and Period-of-Action (POA) planning sessions 

 Requirements / Qualifications 

• BS/MS/PhD in Engineering, Physics, Applied Physics, Statistics, Computer Science, or related quantitative field strongly preferred 

• 6 years of sales operations experience in the pharmaceutical or biotech industry (which may include work as a consultant or supplier to the industry) 

• Expert-level SQL skills for complex queries, joins, and data manipulation. 

• Advanced proficiency in Python (pandas, numpy) or R for data analysis and modeling 

• Advanced Excel capabilities including VBA/macros, Power Query, Power Pivot, and complex formula design 

 Experience, Knowledge and Skills 

• Strong understanding of key pharmaceutical data sources (IQVIA, Symphony, claims data) and data structures to produce actionable insights 

• Excellent written and verbal communication skills with ability to translate complex technical concepts into clear business insights for all organizational levels 

• Experience in hcp segmentation, targeting and resource allocation. 

 Salary & Benefits  

The anticipated salary range for this role is $140,000 - $160,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Senior Manager, Field Effectiveness to build and lead the operational infrastructure for our new Long-Term Care (LTC) sales force targeting demand originating from facility-based settings. This role requires establishing entirely new analytical capabilities around facility-level data, transitioning from traditional physician-focused operations to facility-based commercial models. The position demands technical expertise in data integration, advanced analytics, incentive compensation and operational system design to support PointClickCare data onboarding. In addition this role will support an expanded Digital sales team on reporting, targeting to support geos that have solo coverage and incentive compensation. This role reports directly to the Director, Field Effectiveness.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles. 

Job Responsibilities and Duties include, but are not limited to, the following:

• Lead PointClickCare data integration project to establish facility-based analytics infrastructure, including designing data ingestion pipelines, normalizing facility/resident data structures, and establishing regular refresh cadences
• Build facility-level targeting and segmentation models incorporating census data, prescribing patterns, payer mix, and formulary status
• Develop facility profiling algorithms that identify high-opportunity targets based on disease prevalence, current treatment patterns, and competitive dynamics
• Build comprehensive LTC analytics infrastructure linking LTC rep activity to facility adoption. Implement cohort analysis frameworks to track facility product productivity over time
• Manage ongoing reporting, alignment, call planning, and IC design and admin for the LTC and Digital sales force
• Redesign DSAM targeting to optimize reach and frequency based on whether the hcp is currently covered by dual or single in person sales reps
• Create dashboards and reporting tools showing LTC sales force performance versus traditional team across key metrics, facility-level trends, rep performance, and formulary tracking
• Create ad hoc analyses to identify field execution opportunities based on CRM engagement data and secondary data sources (PCC, Symphony).
• Support LTC and DSAM Sales leadership in the organization and coordination of National Sales Meetings and POA planning sessions
• Collaborate with broader Commercial Operations team on cross-team optimization initiatives

Requirements / Qualifications

• BS/MS/PhD in Engineering, Physics, Applied Physics, Statistics, Computer Science, or related quantitative field strongly preferred
• A minimum of 6 years of sales operations experience in the pharmaceutical or biotech industry (which may include work as a consultant or supplier to the industry)
• Expert-level SQL skills for complex queries, joins, and data manipulation. Advanced proficiency in Python (pandas, numpy) or R for data analysis and automation
• Advanced Excel capabilities including VBA/macros, Power Query, Power Pivot, and complex formula design
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Excellent written and verbal communication skills with ability to translate complex technical concepts into clear business insights for all organizational levels
• Experience in Sales Force Design, Alignment, Targeting, Call Planning, and Incentive Compensation
• Experience in omnichannel planning and supporting Veeva CRM applications

Salary and Benefits:

The anticipated salary range for this role is $140,000 - $160,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role  

Axsome Therapeutics is seeking a Senior Director, Health Economics and Outcomes Research (HEOR) Analytics to lead the design and execution of real-world evidence (RWE) analytics in support of the value proposition of Axsome’s marketed products and pipeline assets. Reporting to the Associate Vice President of Health Economics & Evidence Generation Strategy, the Senior Director, HEOR Analytics will provide hands-on technical expertise and day-to-day partnership with cross-functional teams. The Senior Director HEOR Analytics will oversee complex real-world data (RWD) analyses, ensure methodological rigor, and mentor a team with expertise in real world analysis design, execution, and interpretation.  

This role requires deep expertise in analyzing large-scale healthcare datasets—including administrative claims and electronic health records (EHR)—to generate insights that inform medical affairs, market access, and commercial strategies as needed. HEOR Analytics Lead will work in close partnership with HEOR Product Leads to develop fit-for-purpose analytical plans, with additional input from Medical Directors, Health Outcomes Liaison (HOL) team members, and other cross-functional partners as necessary.  

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.  

Job Responsibilities and Duties include, but are not limited to, the following: 

Technical Leadership & Methodology 

• In partnership with HEOR Leads, design and execute observational research using real-world data sources (claims, EHR, registries) to assess disease burden, treatment patterns, real-world outcomes, and unmet needs 

• Develop advanced analytical approaches including predictive models, comparative effectiveness studies, causal inference frameworks, and longitudinal analyses 
• Ensure methodological rigor in study design(e.g., propensity score matching, IPTW) and advanced statistical modeling 

Data Management & Analytics Execution 

• Lead the integration, management, and analysis of large healthcare databases, including Komodo, Symphony, MarketScan, and EHR databases 

• Implement data cleaning, transformation, and quality assurance processes for high-volume datasets 

• Utilize programming languages (SAS, R and Python to develop statistical models, generate outputs, and visualize results 
• Partner with HEOR Leads and other internal stakeholders to shape Axsome’s real-world data strategy, including evaluating new datasets and potential partnerships  

Evidence Generation & Dissemination 

• Develop statistical analysis plans and oversee high-quality programming deliverables (analysis-ready datasets, tables, and figures) while establishing best practices across teams 

• Contribute to observational study protocols and analysis documents 

• Author and co-author peer-reviewed publications, conference abstracts, and presentations 

• Translate analytical findings into insights that support payer negotiations, value dossiers, medical strategies, and commercial planning 
• Deliver clear, compelling presentations of technical results to non-technical stakeholders 

Leadership & Team Development 

• Manage and mentor a team of real-world evidence analysts, biostatisticians and data scientists, fostering technical excellence and innovation. 

• Oversee resource planning, performance management, and career development for direct reports 

• Drive best practices, innovation, and continuous improvements in HEOR analytics processes and methodologies,  
• Stay current on evolving RWE methodologies, regulatory guidance, and payer expectations; proactively educate internal partners 

Requirements / Qualifications 

• PhD or Master’s in Biostatistics, Epidemiology, Health Economics, or related quantitative discipline 

• 10+ years in HEOR/RWE analytics within the pharmaceutical or biotech industry 

• Minimum of 5 years of people management, team leadership and mentoring experience 
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles 

Experience, Knowledge and Skills 

• Proven experience analyzing large-scale claims and EHR datasets 

• Advanced proficiency in SAS, R, and/or Python for statistical programming 

• Deep expertise in study design and advanced statistical methods (e.g., survival analysis, mixed models, machine learning) 

• Strong publication record in peer-reviewed journals 

• Demonstrated success in using innovative analytical techniques to overcome real‑world data limitations.  

• Knowledge of health economic modeling, patient-reported outcomes (PROs), and outcomes research methods preferred 

• Ability to impact, influence, and interact with senior business leaders and partners 

• Experience with payer evidence requirements, dissemination strategies, and reimbursement/access environments  

• Excellent communication and interpersonal skills across departments and geographic locations 

• Experience managing budget and resource allocation 

• Ability to lead, collaborate, and influence in a matrix, fast-paced environment 

• Flexible, adaptable, diplomatic, and comfortable navigating ambiguity 

• Strong attention to detail with the ability to balance strategic and operational responsibilities 

• Ability to manage multiple priorities aligned with program objectives  
• Launch experience strongly preferred 

Salary & Benefits  

The anticipated salary range for this role is $260,000 – $285,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package. 

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.  

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration. 

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Director/Senior Director, Clinical Development to provide leadership across the full lifecycle of CNS programs, from IND through late-stage development and regulatory submission. The Director/Senior Director, Clinical Development will help shape clinical strategy, contribute to protocol design and key regulatory and clinical documents, and serve as a clinical representative with regulators, investigators, and cross-functional partners.

Job Responsibilities and Duties include, but are not limited to, the following:

• Provide Clinical Development leadership on protocol development, overall study/program, and regulatory submissions 
• Serve as a Clinical Development representative with external stakeholders (e.g., FDA, Principal Investigators, and site staff)  
• Contribute to the development of clinical and regulatory documents, including Clinical Study Reports, Investigator’s Brochures, annual reports (e.g., DSUR), briefing books, and clinical sections of INDs and NDAs  
• Review and contribute to the development of the Statistical Analysis Plan 
• Work in close collaboration with cross-functional departments (e.g., regulatory, clinical operations) to develop and execute program strategies from IND through all phases of clinical development 
• Collaborate with Medical Affairs, HEOR, and the Commercial team to develop the Target Product Profile and overall Value Proposition 
• Develop timelines and integrated program plans for the tracking of product / project deliverables 
• Champion and facilitate program team meetings, cross-functional communication and decision making, ensuring alignment with internal and external stakeholders 
• Partner with the Clinical Operations Study Team to oversee the execution of clinical studies 
• May also serve as lead Medical Monitor on clinical studies (if MD) or may assist Medical Monitor with review of subject eligibility 
• May contribute to pharmacovigilance monitoring AEs, SAEs, and FDA reporting and database reconciliation 
• Participate in clinical data review at the patient level and in aggregate to ensure quality and integrity of study  
• Train clinical study team on therapeutic area, drug product, and protocol, as needed 
• Lead/contribute to publication planning, authoring and presentation of abstracts, posters, slides, and manuscripts 
• Author, review, and revise Standard Operating Procedures (SOPs), as needed 
• Supervise or mentor other Clinical R & D team members 

Requirements / Qualifications

• Post-graduate degree (e.g., PharmD, PhD) or MD required, with at least 10 years of clinical research experience
• Must have at least 4-6 years working in a relevant CNS indication 
• Knowledge of GCP, ICH guidelines and other local guidance, regulation, and codes of practice related to clinical research 
• Ability to work on complex or multiple projects and exercise independent judgment within generally defined practices and policies that lead to obtaining results
• Proven experience in conducting and managing clinical programs (Phase I-IV)
• Demonstrated ability to effectively communicate with and influence individuals at all levels of the organization including situations of conflict resolution and problem solving
• Knowledge of the drug development process with strong understanding of other functions relevant to the position, including clinical operations, biostatistics, and regulatory affairs
• Experience supporting meetings with regulatory agencies (e.g., FDA, EMA, etc.) 
• Willingness to travel as needed
• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience and Knowledge:

• Strong time management skills and ability to effectively manage multiple competing priorities
• Strong interpersonal skills and communication skills (both written and oral) 
• Self-motivated, adaptable to a dynamic environment 
• Comfortable multi-tasking in a fast-paced small company environment and able to adjust workload based upon changing priorities

Salary and Benefits:

The anticipated salary range for this role is $240,000 - $300,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law. 

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.