Position Overview

The Project Manager, Medical Affairs at Adaptive Biotechnologies plays a central role to support product development and commercialization through Medical Affairs-led initiatives, reporting to the Director of Medical Affairs. We are looking for a strategic and results-driven individual who thrives in a fast-paced, collaborative environment. The successful candidate will work cross-functionally to lead and support key projects and initiatives. Projects, including Adaptive-sponsored and Investigator-sponsored research studies, are expected to be scoped comprehensively, completed on time, on budget, to meet the desired goals of the business, with an emphasis on data generation. The role will work independently to plan, direct, track, and coordinate research activities from inception to operationalization.

Key Responsibilities and Essential Functions

• Project Lifecycle Management
  • Lead internal research projects from initiation through completion, including scope definition, planning, execution, and documentation.
  • Track external collaborative research projects to develop and maintain study workflows, assess progress, proactively manage risks, and support timely data availability for analysis, publication and presentation at key congresses.
  • Ensure alignment on project goals, rationale, and roles & responsibilities with stakeholders and leadership.
  • Develop and maintain project charters, timelines and work plans, driving accountability across the team.
  • Facilitate clear communication across project teams, internal partners, functional leaders, and external collaborators.
  • Identify and manage risks and issues, proactively communicating and adjusting plans as needed.
  • Partner with other Program and Project Managers across Adaptive to support infrastructure for project management, prioritization, communication, and institutional knowledge sharing.
  • Participate in cross-functional initiatives as a contributing team member.
• Analysis, Metrics & Reporting
  • Perform / support analysis to inform business case and resource allocation
  • Define metrics for project success and determine how to measure
  • Provide regular reporting on project status to manager and project team, highlighting key risks, issues, and milestones.
• Strategic Planning for Clinical Study Data Generation
  • Contribute to the development and execution of research studies that support MRD product and commercial strategy
  • Clinical study execution support: Track protocol development, contracting, study start-up, and coordinate cross-functional operational workflows (Regulatory/IRB, Clinical Trials, lab teams).
  • IRB protocol coordination: Facilitate IRB protocol submissions and related materials; track IRB protocol progress, approvals, and renewal dates; and coordinate record updates and amendments as required to ensure protocols do not lapse and study activities remain appropriately covered.
  • Visibility + stakeholder communication: Provide clear status reporting, surface critical-path risks, and align on mitigation/alternative plans with Medical Affairs leadership and key stakeholders.
  • Scientific output enablement: Track data generation and publication/congress timelines, maintain data-readiness visibility, and build/maintain tracking tools and outreach tracking for study opportunities/sites.
• All other duties as assigned

Position Requirements (Education, Experience, Other)

Required

• Bachelor’s Degree and 5+ years (or Master’s Degree and 3+ years) of Project Management experience with 2+ years' experience in a biomedical research, biotech, or healthcare setting
• Project Management Professional (PMP) or equivalent certification
• Demonstrated understanding of Project Management processes, strategies and methods
• Familiarity with clinical trial operations
• Proven track record of successful project and/or operational delivery in a biomedical research, biotech or healthcare setting.
• Demonstrated ability to succeed in a deadline-driven environment, solve problems, and prioritize tasks.
• Expertise with the project management life cycle (initiating, planning, executing, monitoring, closing) and change management.
• Expertise with tools that facilitate project management, such as Smartsheet, LucidChart, MS Office suite (Teams, Word, Excel, PowerPoint) and SharePoint.
• Excellent communication skills (oral, written, presenting) with the ability to build relationships across all levels of the organization.
• Self-motivated and works independently, with minimal supervision.
• Strong experience facilitating project team meetings, cross-functional communication and decision-making ensuring alignment with internal and potentially external stakeholders in a highly matrixed organization

Preferred

• Familiarity with regulatory and reimbursement pathways for diagnostic products (e.g., FDA, CLIA, CE-IVD).
• Familiarity with the real-world data/evidence lifecycle, data governance, processes, and operating models.
• Experience from at least two successful commercial product launches in diagnostics.
• Experience working with R&D, clinical, regulatory, marketing, and commercial teams to bring products from concept to market.
• Experience performing business opportunity assessments.

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Compensation

Salary Range: $101,600 - $152,400

Possible “other compensation” elements to include:

• equity grant
• bonus eligible

Position Overview

The Account Operations Manager plays a critical role in driving the successful integration and utilization of Adaptive Biotechnologies’ clonoSEQ® Assay into diverse healthcare settings. With expansive operational expertise and clinical fluency in hematologic disease and MRD testing, the Account Operations Manager translates strategic initiatives into scalable solutions that enhance the end-user experience and accelerate adoption. This customer-facing position leads the design and implementation of tailored diagnostic workflows, ensuring seamless onboarding, and providing comprehensive training for clinical teams. 

Working cross-functionally with field-based teams and internal stakeholders, individuals in this role serve as a trusted partner in navigating complex healthcare systems, supporting EMR integration, and optimizing clonoSEQ testing. The Account Operations Manager is instrumental in shaping the customer journey, educating stakeholders on new support offerings, and contributing to continuous advancements across the diagnostics business.

Key Responsibilities and Essential Functions

Customer Onboarding & Workflow Execution

• Manage institution-specific onboarding requirements and develop customized workflows tailored to each account’s operational and clinical needs.
• Lead virtual or in-person trainings for key ordering personnel and support go-live readiness for diagnostic integrations in non-hospital and academic hospital institutions.

Clinical & Operational Support

• Apply working knowledge of hematologic disease biology, specimen handling, and MRD testing guidelines to support workflow implementation.
• Serve as a resource to internal teams and external stakeholders, helping ensure workflows align with standards of care and institutional protocols.
• Collaborate with sales and customer operations to ensure efficient and effective communication with clinicians and their teams.

Cross-Functional Collaboration

• Partner with sales, field medical, reimbursement, digital health, and customer operations to ensure cohesive execution of account strategies and business goals.
• Act as a liaison to support priority internal initiatives requiring customer engagement and feedback.

Technical Enablement & EMR Support

• Support EMR integration efforts by partnering with technical teams and engaging existing and prospective integration targets.
• Help customers leverage embedded decision support tools to drive diagnostic adoption. Facilitate cross-functional training efforts, enable operational readiness for integration go-live, and coordinate ongoing integrated workflow optimization.
• Provide feedback to internal stakeholders to inform future integration strategies.

Customer Engagement & Education

• Build and maintain strategic relationships with customers, driving satisfaction through superior service and execution.
• Educate customers on new support offerings to maximize brand performance, ensuring alignment with evolving clinical and operational goals.

Operational Excellence & Insights

• Ensure accurate and timely delivery of insights related to new prospects and account health.
• Assist in analyzing trends and providing business context to help identify and advance key growth initiatives.
• Monitor account performance metrics and share observations that inform operational strategies and improvements.

Team Leadership & Mentorship

• Provide training and guidance to new Account Operations team members in coordination with leadership.
• Foster a culture of collaboration, growth, and continuous improvement across the Account Operations team.

All other duties as assigned

Position Requirements (Education, Experience, Other)

Required

• Bachelors + 7 years of related experience in healthcare operations, customer service, account management, or diagnostics/biotech industry.
• Masters + 5 years of related experience in healthcare operations, customer service, account management, or diagnostics/biotech industry.
• Strong customer and patient focus with demonstrated understanding of HIPAA requirements.
• Familiarity with EMR/EHR systems, LIS platforms, and healthcare infrastructure.
• Experience navigating complex workflows and supporting academic, community, and integrated delivery network healthcare organizations.
• Effective and professional communication skills for engagement with both internal cross-functional partners and external customers.
• Proven ability to work in a team environment and influence outcomes in a matrixed organization.
• Strong attention to detail and meticulous data entry skills.
• Ability to autonomously and proactively manage multiple tasks to completion in a dynamic setting.
• Recognized for operational execution and customer-centric problem solving.

Preferred

• 2–4 years of prior experience in a customer-facing commercial role (sales, marketing, or customer support) for a regulated healthcare product preferred.

Working Conditions

• Some travel required (15 - 20%)
• Daily use of a computer and virtual communication tools; must be able to read, write, and communicate clearly in digital formats

This role supports the Southeastern United States and follows Eastern Time business hours (8:30 am - 5:00 pm ET).

#LI-Remote

Compensation

Salary Range: $101,600 - $152,400

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

Adaptive has a growing Pharma MRD business, which includes a portfolio of more than 140 clinical trials under management. The Pharma MRD group engages with new and existing customers to incorporate the Adaptive NGS-based MRD Assay into studies to evaluate minimal residual disease (MRD) as a prognostic and predictive early biomarker of response to assess depth and duration of response to a variety of cancer therapies. The Adaptive NGS-based MRD Assay was granted de novo designation and marketing authorization by FDA (under Section 513(f)(2) of the Food, Drug and Cosmetic Act) in patients with multiple myeloma, acute lymphoblastic leukemia and chronic lymphocytic leukemia under the clonoSEQ® mark.

The Strategic Alliance & Business Development Manager at Adaptive Biotechnologies plays a central role to support the expanding MRD pharma business. The MRD portfolio comprises of exploratory and regulated programs, including high impact, multi-year collaborations and translational partnerships with major biopharmaceutical and biotechnology companies. The Strategic Alliance & Business Development Manager is responsible for supporting and driving ongoing and new business opportunities. This role will contribute  to growing Adaptive’s engagements with biopharmaceutical and biotechnology partners and execution of projects. Reporting to the Director, Strategic Alliance & Business Development, this individual will source, secure, negotiate and close deals with potential industry and institutional customers to leverage Adaptive’s technology platforms, capabilities and expertise. In addition this individual will manage existing customer projects from initiation through completion.

Key Responsibilities and Essential Functions

• Drive prospecting and acquisition of new business with pharmaceutical/ industry customers
• Drive negotiation of new contracts and agreements with industry clients
• Oversee lifecycle management of partnerships/projects, including initiation, contracting, order creation and documentation, and deliverables to external stakeholders
• Represent Adaptive externally and deliver scientific presentations to identify opportunities
• Contribute to new bookings and recognized revenue corporate goals
• Work cross-functionally to manage and deliver deal commitments
• Support business development strategy and initiatives
• All other duties as assigned

Position Requirements (Education, Experience, Other)

• Bachelor’s and 7+ years of experience or Master’s degree with 5+ years experience in academic and biotech industry. Candidates with a PhD and 2 years of post-doc industry experience will also be considered.
• 3+ years of Clinical Lab, Client Services, Business Development or Alliance Management experience preferred.
• PhD degree in immunology, cancer biology, or relevant scientific discipline preferred
• Demonstrated track record of closing transactions.
• Experience in cellular immunology/biology, PCR or NGS-based assays is preferred.
• Experience with clinical trials operations/ design is preferred
• Experience working with internal/external multidisciplinary teams including R&D, Commercial, Legal, IP, Finance and Operations
• Excellent written communication skills are required, including technical computer proficiency (Word, Excel, PowerPoint, etc)
• Ability to work in a matrix environment and leverage cross-functional resources.
• Proactive, self-motivated and able to work independently as well as on a team with the ability to exercise sound independent judgment
• Demonstrated enthusiasm, drive, and energy in building internal and external partnerships and promoting a professional manner.
• Independent strategic thinker with strong ability to solve complex problems.
• Excited about an early stage company environment and driven to make a difference.

Working Conditions

• This position will be field based, may require up to 35% travel from time to time, and a willingness to work according to global hours when needed to support global customers.

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Compensation

Salary Range: $128,700 - $193,100

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

Adaptive’s Legal team is seeking a creative, agile, and diligent Counsel to join Adaptive’s transactional business attorney team.  As an integral member of the Legal Department, this role will work in conjunction with our business clients and other attorneys to handle commercial contract negotiation and drafting, primarily regarding Adaptive’s minimal residual disease (“MRD”) and Immunosequencing assay services for biopharmaceutical customers and investigator-sponsored trials. A portion of this person’s time will also be dedicated to supporting the internal corporate and securities function. 

Key Responsibilities and Essential Functions

• Draft, review and negotiate contractual arrangements for a range of agreements related to Adaptive’s support of customer clinical trials, including MSAs and SOWs with our MRD and Immunosequencing assay biopharmaceutical services teams and MTAs and investigator-sponsored trial agreements with our clinical trials team.
• Partner closely with privacy and compliance attorneys and counterparts in finance, quality assurance, security, regulatory and operations functions to spot issues and carefully evaluate and mitigate risks.
• Provide support on NDAs, vendor contract reviews and vendor management matters.
• Advise on and direct internal traffic regarding routine, ongoing legal queries in the MRD and Immune Medicine businesses, such as contract interpretation, alignment with regulatory requirements, and risk assessments in view of business priorities.
• Support internal Legal teams on general legal matters relating to ex-US expansion opportunities as they arise, which may include contract negotiation, template improvement, jurisdiction-specific research, and other tasks as assigned.
• Assist with preparation of certain SEC filings, including Forms 10-K and proxy statements, in addition to general SEC compliance matters, and potentially help with corporate governance projects.
• Help develop, implement, and maintain contract templates, negotiation playbooks, company policies, and other legal processes to drive value and efficiency, which may include use of and proficiency with artificial intelligence tools.
• Keep informed of new laws, regulations, and industry trends affecting Adaptive.
• All other duties as assigned.

Key Responsibilities and Essential Functions

Required

• Juris Doctorate from a nationally accredited law school and current member in good standing of a U.S. state bar.
• At least 5+ years prior in-house or law firm experience providing transactional legal counsel.
• Ability to travel at least 1-2 times per year for in-person team or department meetings.

Preferred

• Strong preference for candidates with at least 2-3 years in a law firm environment.
• Experience with a biotech and/or the life sciences industry, particularly a diagnostics company, is valued but not required.
• Comfortable with layers of regulatory, compliance and privacy considerations, and a plus if candidates have experience with privacy agreements (e.g., DPAs and BAAs).
• Sound business judgment and ability to navigate complex legal issues without losing sight of the overall business goal.
• Demonstrated client service orientation. Someone eager to establish and own relationships with business owners and who can recognize and respond quickly and pragmatically to demanding clients.
• Strong verbal and written business communication skills are essential: adept at synthesizing and summarizing complex and/or voluminous content into clear, concise and actionable communications, including on legal matters to non-attorneys.
• Ability to work under fast-paced conditions, comfortable making decisions and demonstrates good judgment.
• Strong project management skills: can prioritize multiple tasks and goals to ensure timely, on-target and within-budget accomplishments.
• Initiative to solve problems and help the commercial function within the Legal department drive process improvements and scalability.

Working Conditions

• Office environment. This position is based in Seattle but may be remote.

#LI-Remote

Compensation

Salary Range: $172,000 - $258,000

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

The Payer Contracting Manager initiates, negotiates, and executes Managed Medicaid, State Medicaid, Medicare Advantage and Local market commercial payer, contracts and agreements to reimburse for testing services. The Payer Contracting Manager works assignments involving moderately complex issues where the analysis of situations or data requires an in-depth evaluation of variable factors.

Key Responsibilities and Essential Functions

• Communicates contract terms, payment structures, and reimbursement rates to payers.
• Analyzes financial impact of contracts and terms.
• Maintains contracts and documentation within a tracking system.
• May assist with identifying and recruiting payers based on improving clonoSEQ coverage and reimbursement.
• Begins to influence department’s strategy.
• Makes decisions on moderately complex to complex issues regarding technical approach for project components, and work is performed without direction.
• Exercises considerable latitude in determining objectives and approaches to assignments.
• All other duties as assigned

Position Requirements (Education, Experience, Other)

Required

• 7+ years of experience negotiating managed care contracts with both government and private payers.
• Proficiency in analyzing, understanding and communicating financial impact of contract terms, payment structures and reimbursement rates to payers.
• Excellent written and verbal communication skills
• Ability to manage multiple priorities in a fast-paced environment
• Proficiency in Microsoft Office applications

Preferred  

• Bachelor's Degree
• Experience with payer contracting and network administration any with both commercial, Medicaid and Medicare Advantage
• Knowledge of ACO/Risk Contracting
• Knowledge of Value Based Contracting

Working Conditions

• Travel may be required

#LI-Remote

Compensation

Salary Range: $90,000 - $135,000

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

Adaptive Biotechnologies is seeking a Principal Machine Learning Scientist to lead the development of deep learning models for TCR–pMHC specificity prediction.

In this role, you will leverage a large and growing proprietary dataset to design, train, and evaluate models that predict interactions between T cell receptors and peptide–MHC complexes. Your work will focus on developing new approaches that integrate sequence and structural information and rigorously testing their performance in practical settings.

You will work closely with computational scientists, immunologists, and machine learning engineers across the organization. The team brings together expertise in immune biology, experimental assay development, and large-scale machine learning, with access to proprietary immune receptor datasets, shared GPU infrastructure, and engineering support for model development and training.

This role sits at the intersection of modeling and experimental data generation. As model results highlight gaps in available data or suggest new experimental directions, newly generated datasets can provide additional signal for improving and validating the models.

Models developed in this role contribute directly to diagnostic and therapeutic initiatives both within Adaptive and through external partnerships. This position offers the opportunity to advance predictive modeling of immune receptor specificity while seeing those advances translated into meaningful clinical and commercial applications.

Key Responsibilities and Essential Functions

• Design, implement, and train novel deep learning architectures for TCR–pMHC specificity prediction.
• Extend and adapt advances in protein language models, structure prediction, generative modeling, and representation learning to the immune receptor setting.
• Leverage and influence scalable training infrastructure to support large-scale model development and experimentation.
• Lead rigorous benchmarking and evaluation strategies to ensure models are scientifically sound and practically superior.

Define Modeling and Data Strategy

• Translate biological principles of T cell recognition into principled modeling decisions.
• Influence large-scale experimental data generation to maximize modeling leverage and long-term performance gains.
• Evaluate emerging ML advances and determine when and how to incorporate them into Adaptive’s modeling roadmap.
• Shape the long-term technical direction of machine learning in immune receptor prediction across the organization.

Drive Impact Across the Organization

• Partner with computational biology, immunology, translational, and engineering teams to ensure models are capable, scalable, reproducible, and aligned with therapeutic and diagnostic goals.
• Clearly communicate complex modeling insights to scientific leadership, executives, and external partners.
• Contribute to intellectual property development and high-impact publications.

Position Requirements

Required

• PhD in a quantitative discipline (e.g. Machine Learning, Computational Biology, Computer Science, etc.) + 12 years progressive experience in machine learning, applied statistics or related field in a life sciences or biotech environment or similar combination of education and experience; an advanced degree preferred.
  • Masters + 15 years of progressive experience, or
  • Bachelors + 17 years of progressive experience
• Progressive experience in the conception, development and deployment of deep learning methods including substantial hands-on model development
• Demonstrated track record of innovating and implementing novel machine learning solutions to biological problems, as demonstrated by publications, conference papers, patents, or delivered products.
• Deep expertise in python and modern ML tooling (PyTorch preferred)
• Experience with version control and ML experiment tracking
• Proven ability to independently define, scope, and execute complex technical research problems.
• Excellent written and verbal communication skills, with ability to present highly technical material to diverse audiences.
• Exceptional depth in deep learning architecture design and implementation.
• Comfortable operating at the frontier of both ML and immunology.
• Strategic thinker capable of influencing technical direction across teams.
• Driven by impact: motivated to see models transition from research to clinical and commercial application.

Preferred

• Experience in one or more of the following areas desired:
  • Protein structure prediction
  • Protein design and generative modeling
  • Protein language models and large-scale foundation models
  • Working with large-scale biological datasets
  • Immunology and immune receptor specificity (antibody or TCR)

 #LI-Remote

Compensation

Salary Range: $183,400 - $275,000

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

The Identity & Access Management (IAM) Engineer II develops, implements, and manages the operation of Adaptive’s IAM systems and processes. They will work with business partners and cross-functional teams to provide Identity and Access Management strategies, roadmaps, and program related items to improve the posture of Adaptive’s IAM practice.

Key Responsibilities and Essential Functions

• Own key business processes involved with IAM
  • User Provisioning
  • Role-based Access Control
  • User access request and provisioning
• Automate IAM processes and tasks using standard tools and scripting languages
• Implement best practices for identity governance and administration
• Integrate identity systems with HR, Training, and Quality systems
• Manage onboarding and integration of new business systems
• Establish technology and processes to maintain accuracy of access management system(s)
• Oversee the execution of regular configuration and user access reviews
• Coordinate closely with Information Security
• Ensure the security and protection of company systems and data by maintaining compliance with Adaptive security and information handling policies.
• All other duties as assigned

Position Requirements

• Bachelor degree and 5+ years of related experience, including designing, implementing, and operating enterprise identity and access management technologies, including access request/management, directories and authentication (SSO) systems across diverse in-house and external business systems.
• Broad knowledge of identity and access data correlation, normalization, and building identity and access data models.
• Highly developed interpersonal, written and verbal skills with an ability to express complex technical concepts in business terms. Excellent technical writing and system documentation skills.
• Demonstrated project management skills for large cross-functional projects.
• Strong analytical problem-solving, and conceptual skills.

Required technical competencies and experience:

• Services based Integration (e.g. REST) of role-based access control, Active Directory, LDAP, Single Sign-On, End-User provisioning, identity and access governance, and identity data synchronization services with existing applications and systems.
• API Gateways, Enterprise Directories, Enterprise Databases, SSO and Access Management systems, identity federation protocols (SAML), and LDAP.
• Systems and Applications:
• Active Directory
• O365 and Azure AD
• Okta
• Avatier
• PowerShell
• JavaScript
• SQL scripting

Working Conditions

• Administrative work in a home/office environment.  This is a remote position requiring a quite home office space.
• Regular weekday work hours, with occasional weekend/after-hours planned or unplanned work as needed.

Physical Requirements

• Occasional lifting/moving/installation of computer systems and other office/datacenter equipment.  Occasional work in datacenter environments. Occasional work in laboratory environments requires the use of protective equipment and clothing.

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Compensation

Salary Range: $90,000 - $135,000

Possible “other compensation” elements to include:

• equity grant
• bonus eligible

Position Overview

The VP, Regulatory & Quality will proactively develop, lead, and drive the execution of global regulatory strategy and quality oversight for Adaptive and monitor new regulations and industry guidance to make recommendations to Executive team Heath. As a key leader in the organization, this role is responsible for managing the RA and QA teams to work collaboratively towards defining appropriate regulatory pathways which align with corporate objectives. The VP, Regulatory & Quality leads rapid and timely regulatory plans for Adaptive’s diagnostic products, while advising product development, Medical Affairs, MRD Pharma, Legal, Clinical Lab Operations, Manufacturing and ensuring global regulatory compliance. This position also has responsibility for leading the development, management, and continual improvement of Adaptive’s Quality Management System (QMS).

Leaders at Adaptive demonstrate behaviors consistent with Adaptive’s Core Values and Leadership Principles. Critical functions of your role include helping establish individual team member goals, aligning those individual goals with broader team objectives, and ensuring those objectives drive the achievement of company goals. Providing thoughtful coaching and consistent feedback to your team members will drive performance excellence and accountability, as well as support your team members’ growth and development. Leaders at Adaptive create an environment of belonging, respect, and open and honest communication every day.

Key Responsibilities and Essential Functions

 Senior Leadership

• Serve as a key and active member of the leadership team, working collaboratively to ensure regulatory and quality objectives are met and aligned with Adaptive’s objectives.
• Lead and mentor the Quality Assurance and Regulatory Affairs, delegating appropriate levels of accountability for decision making and clearly communicating requirements and plans, cross functionally within the organization.

Regulatory Affairs

• Provide management and leadership to the Regulatory Affairs organization in the development and implementation of regulatory strategies and processes to inform commercialization plans approvals worldwide.
• Provide counsel, training and interpretation of FDA and global regulatory requirements to all company personnel.
• Oversee preparation and filing of all regulatory documents with the FDA, notifying body, and international regulatory agencies, within applicable regulations and guidelines.
• Provide regulatory oversight and guidance for compliant product promotion.
• Develop and maintain external relationships with relevant opinion leaders and regulatory officials including meeting with pharma partners for clinical trial regulatory strategies, interacting with global regulatory agencies for all regulatory submissions, managing relationship with Authorized Representative.
• Work cross functionally with collaborator to support pharma partner regulatory requirements.
• Direct the development of systems, practices and processes to ensure effective ongoing review of product design or other operational and manufacturing changes.
• Provide leadership, direction and oversight to manage deviation events that may impact compliance status or create business risk.

Quality Assurance & Compliance

• Responsible for strategic leadership of Adaptive’s Quality Management System (QMS).
• Set, maintain, and train cross functional teams on regulatory policies and quality standards for all quality systems and ensure compliance with applicable regulations worldwide.
• Facilitate management review of Adaptive’s QMS to monitor performance and create/support process enhancement initiatives to drive continuous improvement.
• Drive execution of QMS processes through programs, policies and functions that support corporate and product quality.
• Support specific departmental needs to maintain and improve QMS requirements for ongoing laboratory and other operational activities.
• Collaborate cross-functionally with internal departments on strategy development, risk assessments and implementation of quality principles and regulatory requirements.
• Develop and execute quality design and quality assurance strategy for new product development, changes and improvements.
• In support of the quality system, provide effective leadership support, training and guidance to all company personnel.

All other duties as assigned.

Position Requirements (Education, Experience, Other)

Required

• BA/BS undergraduate degree in life sciences. MS, PhD or other relevant advanced degree strongly preferred.
• 20+ years of progressive management experience in global quality assurance and regulatory affairs in a diagnostic, medical device or life sciences technology-driven company. Advanced degree offsets years of experience (MS + 18 and PhD + 12 years of experience)
• Prior experience leading a function or sub-function
• Experience with product submissions in multiple therapeutic areas (hematology, oncology, immunology) and NGS technology highly preferred.
• Experience in strategic planning and collaboration with executives, key operational groups and external partners.
• Expertise with all phases of the product development lifecycle, including feasibility, design, development, transfer, verification and validation activities necessary for research and diagnostic product commercialization.
• Extensive experience in ISO, CLIA, CAP, CLEP, GxP and other Regulatory compliance requirements.
• Proven hands-on experience in submission and approval of global regulatory filings and reporting for US (510(k)) and other key countries/regions, including CE marks.
• History of successful direct interactions and negotiations with regulatory agencies.
• Experience implementing and managing quality/compliance systems and ensuring inspection readiness.

Working Conditions

• Work is performed in an office environment.

#LI-Remote

Compensation

Salary Range: $261,000 - $391,600

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

Adaptive Biotechnologies is a leader in immune medicine and aims to translate the massive genetic code of the adaptive immune system to improve human health. Adaptive has built a robust immune medicine platform that includes proprietary T cell receptor and B cell receptor sequencing technologies.

The Immune Medicine (IM) business includes a growing portfolio of customers at top tier academic institutions and biopharmaceutical and biotechnology companies that incorporate Adaptive’s immunosequencing technologies in different areas of research, including in oncology, autoimmunity, infectious diseases and neurodegenerative disorders. The Immune Medicine team at Adaptive supports customers in incorporating immune receptor data in basic research to better understand disease, host immune response and accelerate the development of innovative drugs.

The Director/Senior Director, Sales & Business Development will execute on IM’s commercial growth strategy. As a player/manager, this role is responsible for generating sales, achieving revenue targets and managing a sales team. This role is accountable for sourcing, structuring, negotiating, closing deals and growing a book of business that includes fee-for-service (FFS) life sciences research offerings and strategic partnerships. This book of business is comprised of a portfolio of pharmaceutical and biotechnology companies as well as academic institutions. The successful candidate will have exceptional sales savvy, negotiation and contract-management skills plus strong deal-making capabilities. This candidate will be responsible for growing existing and securing new accounts that grow research sales revenue to continue to embed Adaptive as the preferred partner and ‘go-to’ immune sequencing platform.

This candidate will demonstrate strong analytical & quantitative skills, critical thinking ability, high attention to detail, ability to derive insights from data and translate into a “story” that can be presented to both technical and non-technical audience. Leaders at Adaptive demonstrate behaviors consistent with Adaptive’s Core Values and Leadership Principles. Critical functions of this sales role include establishing individual goals, aligning those individual goals with broader team objectives and ensuring those objectives drive the achievement of business unit and corporate goals. As a leader, this role will provide thoughtful coaching and consistent feedback to team members to drive performance excellence and accountability, as well as support the group’s growth and development. Leaders at Adaptive create an environment of belonging, respect, and open and honest communication every day.

Leaders at Adaptive demonstrate behaviors consistent with Adaptive’s Core Values and Leadership Principles. Critical functions of your role include helping establish individual team member goals, aligning those individual goals with broader team objectives, and ensuring those objectives drive the achievement of company goals. Providing thoughtful coaching and consistent feedback to your team members will drive performance excellence and accountability, as well as support your team members’ growth and development. Leaders at Adaptive create an environment of belonging, respect, and open and honest communication every day.

This role reports to the Chief Commercial Officer, Immune Medicine.

Key Responsibilities and Essential Functions

• Directly generate IM sales revenue and new bookings.
• Own and manage a growing book of business.
• Drive prospecting, negotiating and closing FFS deals with existing and new customers.
• Manage contracts, contract negotiations (e.g., CDAs, MSAs, SOWs) with new and existing customers.
• Manage sales engagements and negotiations of agreements and statements of work.
• Partner with finance, legal and R&D to execute agreements.
• Develop and deepen relationships with biotechnology, pharmaceutical, academic institutions, CROs, and technology partners.
• Partner closely with Commercial and Lab Operations to meet and exceed customer needs.
• Develop team members, provide timely and constructive feedback and actively manage team member career growth and development.
• Communicate accurately, clearly and succinctly to Adaptive’s leadership and customers.

Position Requirements

For Director:

• Bachelor’s degree with 15+ years of progressive experience in the biotechnology, pharmaceutical or life sciences industry or a similar combination of education and commercial experience; an advanced degree is preferred.
  • Master's degree with 12+ years of progressive experience, or
  • PhD with 8+ years of progressive experience
• 5+ years of progressive experience in sales or commercial leadership in the biotechnology, pharmaceutical or life sciences industry with a proven track record of individually generating revenue by negotiating and closing deals.
• 4+ years' experience supervising a sales team with a track record of growing revenue.

For Senior Director:

• Bachelor’s degree with 17+ years of progressive experience in the biotechnology, pharmaceutical or life sciences industry or a similar combination of education and commercial experience; an advanced degree is preferred.
  • Master's degree with 14+ years of progressive experience, or
  • PhD with 10+ years of progressive experience
• 5+ years of progressive experience in sales or commercial leadership in the biotechnology, pharmaceutical or life sciences industry with a proven track record of individually generating revenue by negotiating and closing increasingly complex deals.
• Experience actively managing and developing sales teams with a track record of growing revenue.

For both Director & Senior Director:

• Strong understanding of research markets and drug development (e.g., genomics, immunology, cell biology, reagents, platforms, data).
• Extensive network with strong relationship building skills.
• Executive presence with the ability to influence senior leadership and C-suite levels.
• Strong presentation, strategic and analytic skills.
• Self-starter mindset; independent thinker with strong ability to solve complex business problems.
• Highly collaborative, results-driven and comfortable operating in fast-paced environments.
• Extensive experience working with multidisciplinary teams (R&D, Legal/IP, Finance, Operations).
• Strong communication, interpersonal skills and good business judgment.
• Ability to work in a matrix environment and leverage cross-functional resources.
• Ability to create a cohesive team culture that achieves individual and team success.

Working Conditions

This position will be field based, may require up to 40% travel and a willingness to work according to global hours when needed to support global customers.

#LI-Remote

Compensation

Salary Ranges:

Director: $183,400 - $275,000
Senior Director: $206,400 - $309,600

Other compensation elements include:

• equity grant
• bonus eligible

Position Overview

At Adaptive, we are revolutionizing diagnostic testing by delivering precise, timely, and actionable insights to healthcare providers and their patients. Our mission is to harness cutting-edge technology and data integration to ensure MRD results drive better clinical outcomes. As part of that mission, we are seeking an Integration Engineer to support EMR and LIS integrations across our clinical network.

This role partners with internal teams, external vendors, and healthcare organizations to deliver and maintain reliable EMR and LIS integrations supporting ordering, results delivery, and clinical data exchange, and owns the technical strategy and integration architecture across a portfolio of customer integrations.

This role is responsible for designing, configuring, testing, and deploying HL7, FHIR, and API-based interfaces and workflows, including establishing establishes reference architectures, standards, and guardrails that drive global process improvements across integration initiatives. This includes analyzing and mapping healthcare data, validating interoperability, and troubleshooting issues to improve stability across systems and reliability across the integration portfolio. Expertise with Mirth Connect is required.

This role also collaborates with product and engineering teams to support live integrations, enhance automation, and optimize performance as Adaptive expands its data connectivity footprint. These collaborative partnerships require the role to demonstrate subject matter expertise as the primary technical function for our integration portfolio and related systems.

Key Responsibilities and Essential Functions

• Collaborate Across Partners: Work with external vendors, EMR partners, and hospital IT teams to negotiate technical scope, SLAs, and timelines. Partner daily with internal stakeholders and departmental leaders to align integration strategy with business imperatives.
• Drive Support Processes and Technical Operations: Design and operate technical onboarding/go‑live playbooks and post‑launch support models. Define and own SLOs, error budgets, error monitoring, and incident response processes. Lead major incident resolution and root‑cause analysis; implement corrective actions that improve system-wide reliability and efficiency.
• Design and Validate Interfaces: Define architecture for HL7, FHIR, and API-based interfaces across EHR platforms (Epic, Cerner, Athena, etc.). Standardize mappings, streamline validation, and maintain configurations to ensure compliance and interoperability at scale.
• Ensure Data Quality: Analyze, map, and troubleshoot clinical data to maintain accuracy and integrity across systems. Engineer data quality controls and maintain test plans to ensure scalability across platforms.
• Enhance and Optimize Solutions: Partner with product and engineering teams to support live integrations by owning technical integration health measurement, KPIs, and performance visualization. Drive automation for deployment, testing, and monitoring. Continuously drive workflow evolutions to improve reliability across the portfolio.
• Serve as Integration SME: Provide expert guidance on EMR connectivity, interface troubleshooting, and best practices for scalable deployment. Represent the technical function on organization‑wide initiatives and communicate complex concepts to non‑technical audiences.
• Standardize and Scale: Author and maintain standards, documentation, playbooks, and SOPs that enable efficient, repeatable integrations. Establish change‑management and versioning practices to ensure consistency and auditability across deployments.
• Advance Integration Strategy: Co-develop the long-term connectivity roadmap through ownership of technical infrastructure decisions for integration platforms. Evaluate emerging standards with internal stakeholders to ensure alignment with organizational and interoperability goals.
• All other duties as assigned

Position Requirements (Education, Experience, Other)

Required

• Bachelor’s degree + 7 years of experience of related experience (or Master’s + 5 years) in Health IT integration, EMR interoperability, or a closely related field
• Proven technical leadership of multiple cross‑functional integration initiatives
• Deep proficiency in HL7 v2 (ADT, ORU, ORM, etc.), FHIR (R4), and API-based integrations (REST, SOAP, OAuth 2.0, JSON, XML)
• Hands-on experience with EHR systems such as Epic (Aura, Care Everywhere), Cerner, Flatiron, or similar platforms
• Mirth Connect expertise
• Strong JavaScript for data validation and troubleshooting, familiarity with Unix command-line, Git, and serialization formats (JSON, CSV, XML)
• Demonstrated ability to analyze, map, and validate healthcare data to ensure data quality and interoperability; demonstrated ability to implement function‑wide quality controls that improve overall efficiency and reliability
• Deep understanding of HIPAA, PHI security, and regulatory compliance in clinical data exchange environments; ability to embed these requirements in standards and operational practices
• Proficiency with monitoring and logging tools to track interface performance and resolve production issues, define KPIs, and drive incident/issue-management improvements
• Exceptional communication and documentation skills; able to translate technical concepts for non-technical audiences, including business leadership, and mentor client/internal teams
• Demonstrated success managing multiple concurrent integrations with detailed workflows, test plans, and go-live documentation
• Detail-oriented with a focus on system stability, data integrity, and post-go-live optimization

Preferred

• Experience with genetics, oncology, laboratory workflows, or clinical decision support integrations
• Strong analytical and problem-solving skills with a commitment to clear, scalable documentation
• High emotional intelligence and proven ability to thrive in fast-paced, dynamic environments while managing competing priorities
• Passion for exceptional client service and intrinsic motivation to deliver excellence in diagnostics or health IT settings

Working Conditions

• Primarily remote with infrequent travel (up to 5%) for client engagements, go-lives, and/or training.
• May require occasional work during evenings or weekends to support critical implementations.
• Daily use of a computer and virtual communication tools; must be able to read, write, and communicate clearly in digital formats

#LI-Remote

Compensation

Salary Range: $90,000 - $135,000

Other compensation elements include:

• equity grant
• bonus eligible