Senior Manager, Data Science

Portfolio Management and Loss Mitigation

The Role: 

SoFi is seeking an inspirational and deeply experienced Senior Manager to lead the Portfolio Management and Loss Mitigation function in our Risk Data Science team. Reporting to the Head of Risk Data Science, this role will lead the development, deployment, and governance of portfolio management and loss mitigation models for all credit products.

The ideal candidate is a hands-on leader who can transition the team from traditional modeling to next-generation machine learning platforms, leveraging emerging data sources (e.g., cash flow, alternative bureaus) to significantly improve portfolio performance, reduce losses, and ensure rigorous adherence to Model Risk Management (MRM) standards. This role requires exceptional organizational leadership, an ability to influence stakeholders, and proven success in delivering complex models into a regulated production environment.

What You'll Do: 

• Portfolio Management and Loss Mitigation Excellence: Directly oversee the development and deployment of Next Generation models designed to manage and mitigate portfolio losses while maintaining loss guardrails.
• Drive Next-Generation Capabilities: Incorporate industry trends and advanced techniques (NLP, Graph Mining, LLMs, Deep Learning) to solve complex, high-impact risk problems where established principles may not fully apply.
• Alternative Data Strategy: Spearhead the evaluation and integration of alternative data sources (Macro-Economic variables, tri-bureau, LexisNexis, cash flow data) to enhance predictive power across all credit products.
• Lead the current team of high-performing Staff and Senior Data Scientists. Recruit, mentor, and foster talent through deliberate interactions, succession planning, and creating a high-accountability, low-ego culture.
• Model Risk Management (MRM): Act as the primary owner for all models in the portfolio, ensuring robust documentation, monitoring, and successfully navigating the 2nd Line of Defense (2LOD) review and approval process (SR 11-7 familiarity is mandatory).
• Stakeholder Alignment: Interact and negotiate with senior management and external stakeholders to reconcile competing views and drive critical, high-impact business decisions.
• Automation and Efficiency: Lead efforts to automate model monitoring and governance processes to create scalable and auditable infrastructure.

What You'll Need:

• Experience: 8+ years of progressive experience in credit risk, modeling, and data science within a regulated financial institution (FinTech, Bank, or similar), with at least 3 years in a people management role, managing technical staff.
• Education: Master’s or Ph.D. degree in a quantitative field (Statistics, Computer Science, Engineering, Operations Research, etc.).
• Technical Acumen: Deep expertise in advanced statistical and machine learning modeling techniques (e.g., Gradient Boosting, Deep Learning, Causal Inference).
• Regulatory Knowledge: Detailed working knowledge of model risk management standards (e.g., SR 11-7) and the ability to operate within a highly regulated environment.
• Tools & Platforms: Expert-level proficiency in Python (PySpark, scikit-learn, TensorFlow/PyTorch) and SQL/data warehouse technologies (e.g., Snowflake, Hive). Familiarity with modern MLOps platforms and cloud computing (AWS).
• 3+ years of progressive people management experience is required, including the ability to recruit, mentor, and foster talent within a team of high-performing Staff and Senior Data Scientists.
• Communication: Ability to distill highly complex analytical concepts into clear, concise, and compelling narratives for non-technical leadership.

The Impact You'll Make

Recursion is at the forefront of reimagining drug discovery by integrating technological innovations across biology, chemistry, automation, data science, and engineering to radically improve lives by industrializing drug discovery. We are seeking an experienced Associate Director to join our Discovery Biology team to lead and advance our AI-driven portfolio of therapeutic candidates.  

This is a truly unique opportunity to work at the dynamic intersection of technology and biology. You won't just manage projects and key initiatives; you will be an active catalyst contributing to the evolution of a new, powerful paradigm in medicine.

In this Role, You Will:

• Play a critical role in defining and executing our oncology strategy, seamlessly integrating traditional drug discovery principles with cutting-edge in silico computational approaches. 
• Lead scientific initiatives focused on successfully delivering various small molecule programs from initial hit to candidate selection and IND submission. 
• Contribute to novel target insight generation, patient refinement and patient selection strategies within several early discovery programs and have the opportunity to improve the Recursion OS itself. 

The Team You'll Join

You will be an integral part of the Discovery team, working collaboratively with a diverse group of life scientists, computational and technical experts. You will work cross-functionally with team members from various disciplines, including data science, computational biology, pharmacology, DMPK, and chemistry, to accelerate the progression of compounds through the portfolio. This team is responsible for guiding the foundational biology and the critical "tech-to-program" translation across our early Discovery oncology portfolio. 

The Experience You'll Need

• PhD in a relevant biological science discipline (e.g., Molecular Biology, Oncology, Pharmacology, Biochemistry, Computational Biology) with at least 7+ years of experience in Tech-forward Biotech or Pharma 
• A proven track record of accomplishments in drug discovery, with specific experience in operating as a Scientific Team Lead for oncology and/or immuno-oncology programs from early discovery to a clinical candidate stage
• Demonstrated experience with modern drug discovery approaches, including familiarity with AI/ML-driven platforms and models, high-throughput screening, ‘omics data analysis, with a systems biology mindset.
• Strong understanding of the oncology landscape, including key therapeutic modalities, emerging targets, and clinical development challenges.
• Exceptional leadership and interpersonal skills, with the ability to lead and motivate high-performing, cross-functional teams in a fast-paced, matrix environment.
• Demonstrated ability to deliver impactful, clear presentations and memos to a wide range of audiences, including the Executive Leadership Team (ELT), program teams, Key Opinion Leaders (KOLs), and external partners.A strategic and tactical thinker who can prioritize competing demands and solve complex problems with a solution-focused mindset.

Working Location:

This is an office-based, hybrid role in our Salt Lake City / New York City office. Employees are expected to work in the office at least 50% of the time. 

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $198,000 - $271,700 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.

#LI-EP1

The Impact You'll Make

Recursion is at the forefront of reimagining drug discovery by integrating technological innovations across biology, chemistry, automation, data science, and engineering to radically improve lives by industrializing drug discovery. We are seeking an experienced Associate Director to join our Discovery Biology team to lead and advance our AI-driven portfolio of therapeutic candidates.  

This is a truly unique opportunity to work at the dynamic intersection of technology and biology. You won't just manage projects and key initiatives; you will be an active catalyst contributing to the evolution of a new, powerful paradigm in medicine.

In this Role, You Will:

• Play a critical role in defining and executing our oncology strategy, seamlessly integrating traditional drug discovery principles with cutting-edge in silico computational approaches. 
• Lead scientific initiatives focused on successfully delivering various small molecule programs from initial hit to candidate selection and IND submission. 
• Contribute to novel target insight generation, patient refinement and patient selection strategies within several early discovery programs and have the opportunity to improve the Recursion OS itself. 

The Team You'll Join

You will be an integral part of the Discovery team, working collaboratively with a diverse group of life scientists, computational and technical experts. You will work cross-functionally with team members from various disciplines, including data science, computational biology, pharmacology, DMPK, and chemistry, to accelerate the progression of compounds through the portfolio. This team is responsible for guiding the foundational biology and the critical "tech-to-program" translation across our early Discovery oncology portfolio. 

The Experience You'll Need

• PhD in a relevant biological science discipline (e.g., Molecular Biology, Oncology, Pharmacology, Biochemistry, Computational Biology) with at least 7+ years of experience in Tech-forward Biotech or Pharma 
• A proven track record of accomplishments in drug discovery, with specific experience in operating as a Scientific Team Lead for oncology and/or immuno-oncology programs from early discovery to a clinical candidate stage
• Demonstrated experience with modern drug discovery approaches, including familiarity with AI/ML-driven platforms and models, high-throughput screening, ‘omics data analysis, with a systems biology mindset.
• Strong understanding of the oncology landscape, including key therapeutic modalities, emerging targets, and clinical development challenges.
• Exceptional leadership and interpersonal skills, with the ability to lead and motivate high-performing, cross-functional teams in a fast-paced, matrix environment.
• Demonstrated ability to deliver impactful, clear presentations and memos to a wide range of audiences, including the Executive Leadership Team (ELT), program teams, Key Opinion Leaders (KOLs), and external partners.A strategic and tactical thinker who can prioritize competing demands and solve complex problems with a solution-focused mindset.

Working Location:

This is an office-based, hybrid role in our Salt Lake City / New York City office. Employees are expected to work in the office at least 50% of the time. 

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $198,000 - $271,700 (USD). You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.

#LI-EP1

The Impact You’ll Make

As a computational biology specialist on our Target ID team, you will be at the forefront of transitioning Recursion to its next era of drug discovery. You will serve as a critical biological anchor for a highly technical data science team building the next generation of our target discovery pipelines.

The team’s mission is to identify novel therapeutic targets at scale across the genome for hundreds of indications. You will have access to all of Recursion's data layers—including massive internal maps, functional genomics, and rich patient data (transcriptomics, genetics, and Real-World Data/EHR)—and will be tasked with proposing, piloting, and deploying new methods to integrate these datasets.

Crucially, you will leverage your biological subject matter expertise to orient and focus your data scientist and software engineer peers towards reliable and correct usage of biological data and feasible candidate programs. As we build out semi-automated and agentic tools (e.g., multi-agent LLM systems for portfolio oversight and target assessment), your deep real-world biology experience will guide the development of these tools, ensuring they are grounded in biological reality and translate to meaningful portfolio and patient impact.

The ideal candidate is a computational biology specialist with high fluency in data science tech stacks. You know how to build and evaluate predictive models and build agentic pipelines, and your differentiator is your deep understanding of patient-relevant datasets, disease biology, and target discovery.

In this role, you will:

• Discover & Evaluate: Propose and validate novel targets using deep integration of patient data (transcriptomics, population genetics, EHR, etc) and Recursion's internal multi-omic data layers.
• Guide & Automate: Collaborate closely with data scientists to build, refine, and guide semi-automated and agentic target discovery tools. You will ensure these tools are biologically sound and can scale to evaluate hypotheses across many indications spanning a wide range of therapeutic areas.
• Triangulate: Use advanced statistical methods (e.g., causal inference, survival modeling) to establish confident target-to-patient connections and define specific addressable patient populations for early pipeline programs.
• Bridge the Gap: Translate complex platform findings into disease-relevant applications, bridging the gap between high-dimensional data science output and actionable drug discovery insights.
• Present & Influence: Communicate complex biological rationale and data analyses to decision-makers and cross-functional stakeholders, driving data-backed "go/no-go" decisions in a two-stage target approval process.

The Team You’ll Join

Our group is a bold, agile, diverse collective of data scientists and computational biologists driving Recursion’s early portfolio strategy. We are focused on aggressively expanding our early-stage pipeline with highly validated, novel therapeutic targets. To achieve this, we prioritize defining specific patient populations and establishing clear, data-backed translational paths from day one of every new program.

Because this team is dominated by experts in traditional data science, AI/ML, and software engineering, your role is absolutely critical. You will provide the essential biological experience and subject matter expertise to improve and accelerate the work of your peers. Essential attributes for this role include a bold, execution-first attitude, high technical fluency to collaborate seamlessly on data-science-heavy codebases, and a passion for deploying rigorous science to develop life-changing medicines.

The Experience You’ll Need

• PhD in Computational Biology, Bioinformatics, Human Genetics, Systems Biology, or a closely related field with 3+ years of experience in the biotech or pharma industry OR MS in a relevant field and 5+ years of industry experience focusing on target ID or early drug discovery.
• Biological SME: Deep, real-world experience in target discovery, functional genomics, and understanding the druggability of disease-relevant pathways.
• Data Science Fluency: Highly proficient in Python and/or R, with a strong ability to seamlessly integrate into a data-science-heavy tech stack. Comfortable with modern software engineering practices, cloud computing, and machine learning concepts.
• Patient Data Expertise: Extensive experience working with "discovery-related" human data, particularly transcriptomics (bulk/single-cell), patient genetics/GWAS, and clinical/real-world data (e.g., EHR).
• Analytical Rigor: Experience applying advanced computational and statistical methods to establish biological causality (e.g., survival analysis, causal inference modeling).
• Excellent cross-functional communication skills, with a proven track record of upskilling peers in biological concepts and guiding technical teams toward translatable biological outcomes.

Nice To Have:

• Experience working with, prompting, or integrating Large Language Models (LLMs) and autonomous agentic workflows into scientific research.
• Familiarity with building or utilizing Knowledge Graphs for target identification.
• Experience working in the field of oncology or immunology.

Working Location & Compensation:

This is an office-based, hybrid position at our US headquarters located in Salt Lake City, Utah. Employees are expected to work in the office at least 50% of the time.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $151,800 to $230,000. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package. 

#LI-EP1

ABOUT THIS OPPORTUNITY

We are looking for a Data Scientist who views machine learning as a product, not just a research project. You will be a foundational member of our AI team, responsible for designing, building, and deploying sophisticated models that solve complex business problems. You aren't just an expert in XGBoost or Transformers; you are an expert in building the pipelines that make these models reliable, scalable, and impactful.

WHAT YOU'LL DO
^{Essential Job Duties & Functions}

• End-to-End Model Development: Design and implement the full ML lifecycle—from exploratory data analysis (EDA) and feature engineering to model selection, tuning, and validation.
• GCP Architecture: Leverage the full Google Cloud AI suite (Vertex AI, BigQuery ML, Dataflow, and Pub/Sub) to build robust, cloud-native ML solutions.
• MLOps & Engineering: Implement CI/CD for machine learning (CT - Continuous Training) to ensure models remain performant in production environments.
• Strategic Leadership: Partner with stakeholders to translate ambiguous business challenges into technical roadmaps. Mentor junior scientists and advocate for best practices in code quality and experiment tracking.
• Look for opportunities to embed AI as a repeatable co-pilot in daily workflows by integrating experimentation into real work, and continuously refining its use with sound judgment and validation.

WHAT YOU’LL BRING

• 5+ years in a professional Data Science role with a track record of deploying models at scale.
• Proficiency in Vertex AI, BigQuery, Cloud Storage, and Looker. Experience with Kubeflow is a major plus.
• Expert-level Python (pandas, scikit-learn, PyTorch/TensorFlow), Spark, and advanced SQL.
• Deep understanding of statistics and ML theory (e.g., Gradient Descent, Bias-Variance tradeoff, Bayesian inference).
• Experience with ETL/ELT processes, specifically using dbt.
• A strong curiosity for exploring new technologies, including AI
• A shared passion for and ability to demonstrate onX’s Company Values.
• Permanent US work authorization is a condition of employment with onX.

Our Tech Stack

• Data Warehouse: BigQuery
• Orchestration: Airflow (Cloud Composer)
• Modeling: Vertex AI Pipelines, JupyterLab
• Deployment: Docker, GKE (Google Kubernetes Engine)

Pro Tip for the Candidate: We value "clean code" as much as "smart math." If you treat your notebooks like production scripts and your Git history is a work of art, you’ll fit right in.

What Sets You Apart

• The "Product" Mindset: You understand that a model with 99% accuracy is useless if it costs more to run than the value it creates.
• Infrastructure as Code: You are comfortable with Terraform or similar tools to manage your cloud resources.
• Communication: You can explain the "why" behind a complex neural network architecture to an executive without using jargon.

THE ONX EXPERIENCE

onX is a distributed company with more than 400 employees across the country. We come together regularly to work in person and stay connected through regional basecamps and a culture that balances individual ownership with deep collaboration.

While we move quickly, we’re not a scrappy start-up. We operate with clear goals, structure, and frameworks that guide how we prioritize and execute. Priorities matter. While they may shift, data shapes how we evolve as our business, products, and the world around us change.

Clear priorities and structure don’t limit ownership - they make it possible. You’ll have the autonomy to define your work and make meaningful decisions within clear strategic boundaries. You’ll partner closely with others to solve complex problems and build solutions that scale across teams and platforms. Along the way, you’ll be supported with feedback, tools, and opportunities to grow your craft as you take on new challenges.

WHERE YOU CAN WORK

onX has created a thriving distributed workforce designed to foster connection, collaboration, and shared experience across several US locations. We have two HQ locations in Bozeman and Missoula, MT and established virtual workforce Basecamps in Austin, TX; Denver, CO; Kalispell, MT; Minneapolis, MN; Portland, OR; Salt Lake City, UT; and Seattle, WA.

HOW YOU’LL BE COMPENSATED

onX is committed to compensating all employees fairly and equitably for their contributions. For this position, applicants can expect to make between $126,000 to $149,000 upon hire. The pay range will vary based on experience, skills, certifications, and education among other factors as required in the job description. In addition, full-time onX employees are eligible for a grant of common share options with a vesting schedule and a potential annual bonus of 10% based on company performance.

WHAT WE’RE OFFERING YOU

• Competitive salaries, annual bonuses, equity, and opportunities for growth
• Comprehensive health benefits, including a no-monthly-cost medical plan
• Paid parental leave of 13 weeks for birthing parents and 5 weeks for non-birthing parents
• 401k matching at 100% for the first 3% you save and 50% from 3-5%
• Company-wide outdoor adventures and amazing outdoor industry perks
• Annual “Get Out, Get Active” funds to fuel your active lifestyle
• Flexible time away package that includes PTO, STO, VTO, and paid holidays

PERFORMANCE ESSENTIALS

In this role, success is driven by cognitive abilities such as concentration and problem-solving, essential for our computer-centric tasks. onX will explore reasonable accommodations to ensure that individuals with diverse abilities can fully engage in and contribute to the essential physical and mental functions of the job. If you need assistance or accommodation, please contact us at PC@onxmaps.com. 

Application Deadline is [day of week], [month] [day] at [0:00 pm] MST

Position open until filled. 

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