Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role

Axsome Therapeutics is currently searching for a field based Long-Term Care (LTC) Specialty Account Manager (SAM) to drive LTC commercial activities for an assigned geography by executing marketing strategies to ensure a successful launch and make a meaningful difference through the execution of commercial activities.

SAMs will be responsible for product performance at a territory level and expected to be a disease state expert, product champion and an account specialist. The SAM will provide account management support and exhibit business knowledge of the local landscape to assess key stakeholders plus future trends within the marketplace.

Job Responsibilities and Duties include, but are not limited to, the following:

• Drive product adoption in LTC facilities
• Proficient in both virtual and live customer engagements
• Effectively call on LTC Care teams, building meaningful relationships across the entire LTC ecosystem: Psychiatrists, Neurologists, nurse practitioners, Physician assistants, Nurses and LTC staff, Closed-door pharmacies, clinical pharmacists, case managers and care coordinators.
• Develop a comprehensive and effective territory business plan inclusive of account plans for targeted LTC facilities aimed at achieving and exceeding quarterly & annual goals established by commercial leadership
• Promote within our approved labeling in a comprehensive, fair, and ethical manner that is consistent with industry specific and corporate legal and regulatory guidelines
• Develop strong customer relationships by better understanding the customer’s needs
• Serve as a resource/consultant to customers and staff regarding payer policies and processes (i.e., eligibility and benefit verification, prior-authorization, and appeals/denials)
• Navigate Market Access and Reimbursement. LTC SAMs must understand: payer requirements, pharmacy fulfillment processes, patient access programs, reimbursement tools such as cover my meds
• Maximize use of marketing resources to maintain and develop customer relationships for the purpose of growing the customers’ confidence to prescribe Axsome medications for appropriate patients
• Communicate territory activity in an accurate and timely manner as directed by management
• Provide feedback to sales and commercial leadership, colleagues, marketing, and other internal departments about changing environment and results
• Successfully complete all training classes in a timely manner
• Complete administrative duties in an accurate and timely fashion
• Manage efforts within assigned promotional budget
• Effectively collaborate across all corporate functions
• Attend medical congresses and society meetings as needed
• Ensure timely access for patients through patient services and savings programs
• Overnight travel as indicated by the needs of the business
• Additional responsibilities as assigned

Qualifications / Requirements 

• Bachelor’s degree from an accredited college or university 
• Minimum of 5 years of pharmaceutical/biotech sales experience, including 2+ years in LTC or account-based selling environments
• Demonstrated experience delivering outstanding results, including Top 10% or Elite/President’s Club performance
• Launch experience strongly preferred 
• Must live within the geography of the assigned territory
• Experience collaborating with cross-functional teams, utilizing differential resources to achieve business goals 
• Proven ability to successfully manage multiple tasks concurrently under accelerated timelines in a dynamic environment 
• Ability to thrive with ambiguity and business environments with high expectations
• Patient support services experience a plus 
• Strong digital marketing aptitude 
• Strong interpersonal, presentation, and communication skills 
• Frequent driving, including extended periods of time behind the wheel
• Prolonged sitting and standing as part of daily job functions
• Ability to lift and carry up to 30lbs regularly
• Overhead reaching required to close and secure liftgates or similar equipment

Salary & Benefits

The anticipated salary range for this role is $100,000 - $150,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

POSITION OVERVIEW:
Syner-G is seeking a Sr. Automation Engineer with 7–11 years of experience and strong hands-on expertise in Ignition SCADA, PLC-level programming (Rockwell and/or Siemens), and exposure to modern digital or MES-lite system architectures. This role leads the oversight, documentation, and lifecycle management of automation and digital systems in GMP-regulated environments. The Sr. Automation Engineer will act as a senior technical authority, driving automation strategy, ensuring system reliability and compliance, and supporting complex troubleshooting and integration efforts across client engagements.

WORK LOCATION: Travel to client sites may be required up to 100%, depending on project needs and client expectations.

KEY RESPONSIBILITIES: (This list is not exhaustive and may be supplemented or changed as necessary.)

• Lead development, maintenance, and review of automation system documentation, including SOPs, design documents, and lifecycle deliverables such as DS, FS, CA, RTM, and RA.
• Oversee system lifecycle activities, periodic reviews, and audit readiness aligned with regulatory expectations and industry best practices.
• Author, review, and execute complex validation documentation including IOQs, engineering tests, protocols, and summary reports.
• Drive CSV and SDLC processes with strong traceability, risk assessments, and compliance rigor.
• Perform advanced data and system reviews, including alarm rationalization, user access audits, and performance evaluations.
• Own and manage automation-related change records, including impact assessments, stakeholder coordination, and documentation updates.
• Oversee and coordinate maintenance activities, work orders, and system enhancements across automation and digital platforms.
• Collaborate with internal teams and external vendors to resolve complex issues, support upgrades, and implement system improvements.
• Serve as a senior liaison between Facilities, Quality, IT, Operations, and external partners.
• Mentor junior and mid-level automation staff, providing technical leadership and oversight. 
• Lead audit preparation activities and ensure systems remain inspection-ready at all times.
• Provide subject-matter leadership in Ignition SCADA configuration, scripting, module management, and integration with PLCs and MES-lite systems.
• Support PLC and SCADA programming, troubleshooting, and optimization across Rockwell, Siemens, and related control platforms.
• Contribute to digital transformation initiatives, including MES-lite deployments, data modeling, historian integration, and OT/IT convergence efforts.

QUALIFICATIONS AND REQUIREMENTS:

Education:

• BS or MS in Engineering, Life Sciences, or a related technical field preferred.

Experience: 

• 7–11 years supporting and leading automation initiatives in GMP-regulated biotech or pharmaceutical environments.
• Hands-on experience with Ignition (Inductive Automation) for SCADA/HMI development, scripting, gateway configuration, and system integration.
• PLC-level programming experience with Rockwell ControlLogix or CompactLogix and/or Siemens S7 or TIA Portal.
• Experience with BAS/BMS, EMS, or process automation platforms such as Siemens Desigo, DeltaV, Rockwell, or PLC/SCADA systems.
• Exposure to modern digital or MES-lite stacks such as Ignition Perspective, Sepasoft modules, lightweight MES workflows, data lakes, or historians.
• Extensive background in GMP documentation, validation, and CSV/SDLC processes.
• Demonstrated ability to lead technical efforts, manage complex automation projects, and support SMEs through strong documentation, coordination, and compliance execution.

Technical Skills:

• Strong understanding of automation system architecture, control logic, alarm logic, and point configuration review.
• Strong Ignition development skills including Vision or Perspective, scripting, UDTs, tag structures, and gateway configuration.
• Advanced skill in writing, reviewing, and managing controlled documents and validation protocols. Strong leadership, communication, organization, and cross-functional coordination abilities.
• Ability to manage multiple high-priority tasks in a fast-paced, compliance-driven environment.

ESSENTIAL FUNCTIONS:

Physical Demands: 

The physical demands described here are representative of the requirements that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. 

While performing the duties of this job, the employee is regularly required to use a computer keyboard and mouse; reach with hands and arms; talk and listen. The employee is frequently required to walk and sit, as well as to lift and carry objects such as books and files weighing up to 25 pounds. The employee is occasionally required to stand, stoop, or kneel. Specific vision abilities required by this position include close vision and the ability to adjust focus. 

Work Environment: 

The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job, including moderate noise level, an indoor temperate environment, and light levels that are bright and conducive to minimal eye strain, typical for an office environment. 

TOTAL REWARDS PROGRAM:

We define total rewards as compensation, benefits, remote work/flexibility, development, recognition, and our culture with programs that support each of our reward pillars. This includes a market competitive base salary and annual incentive plan, robust benefit offerings, and ongoing recognition and career development opportunities. Employees also enjoy our generous flexible paid time off program, company-paid holidays, flexible working hours, and fully remote work options for most positions and the ability to work “almost anywhere.” However, if a physical work location is more for you, we have office locations in Greater Boston; San Diego, CA; Boulder, CO; and India.

LEGAL STATEMENT:
 
Syner-G is proud to be an Equal Employment Opportunity and Affirmative Action employer. All employment decisions, including the recruiting, hiring, placement, training availability, promotion, compensation, evaluation, disciplinary actions, and termination of employment (if necessary) are made without regard to the employee’s race, color, creed, religion, sex, pregnancy or childbirth, personal appearance, family responsibilities, sexual orientation or preference, gender identity, political affiliation, source of income, place of residence, national or ethnic origin, ancestry, age, marital status, military veteran status, unfavorable discharge from military service, physical or mental disability, or on any other basis prohibited by applicable law. Syner-G is an E-Verify employer. 

Job Title: Senior Director, Corporate Operations

Location(s): Pittsburgh, PA or Remote

Job Status: Full-Time

Supervisor: Chief Operations Officer (COO)

Position Overview

The Senior Director, Corporate Operations will report to the COO and play a critical role in driving the execution of Peptilogics’ operational and strategic priorities. This individual will partner with executive leadership to translate business goals into actionable plans, oversee cross-functional operations, and optimize systems and processes to support growth. The Senior Director will have broad exposure across the organization, with a focus on enabling execution, improving scalability, and contributing to key strategic initiatives.

Essential Functions

• Serve as a key operational leader, partnering with the COO and executive team to align strategy with execution
• Lead company-wide operational planning and ensure alignment with strategic goals
• Facilitate forecasts, budget development, resource allocation, vendor payments, and operational performance tracking with Finance
• Implement and improve systems, processes, and tools to drive operational scalability and excellence
• Implement and maintain the Quality Management System (QMS) and oversee SOP creation, updates, and audit readiness
• Ensure compliance across corporate operations, development activities, legal, insurance, and regulatory requirements; foster a culture of compliance
• Oversee management of non-owned physical facilities (labs, offices, external manufacturing sites), IT infrastructure, and enterprise software systems
• Work closely with the Development team to manage relationships with CROs, CMOs, and preclinical and clinical trial providers
• Lead sourcing, procurement, and logistics to support research, development, and external manufacturing operations
• Negotiate contracts and ensure cost-effective resource utilization across all operational activities
• Manage HCP contracting and compliance processes
• Serve as primary point of contact for legal service vendors and coordinate legal operational needs
• Identify operational risks, gaps, and bottlenecks, and proactively lead solutions
• Manage the Operations team including hiring, performance, coaching, and career development
• Drive operational KPIs and reporting, including preparation of materials for executive and board updates
• Ensure operational compliance with company policies, regulatory requirements, and best practices

Additional Duties and Responsibilities

• Support business development and partnership activities through operational due diligence and integration planning
• Support fundraising and investor relations by providing operational insights, data, and reporting
• Support cross-functional teams (R&D, Commercial, Project Management) in executing strategic initiatives
• Collaborate with the COO and Finance on long-range planning and scenario modeling
• Contribute to shaping company culture by supporting initiatives around collaboration, communication, and team building
• Perform other duties as assigned

Required Qualifications and Skills

• Bachelor’s degree in a relevant field (e.g., life sciences, business, engineering); advanced degree (MBA, MS, PhD) preferred
• 10+ years of experience in biotech, pharmaceutical, or life sciences operations
• 3–5 years in a leadership or senior operations role, ideally in a high-growth or venture-backed environment
• Experience scaling operations in a startup or growth-stage company (preferred)
• Prior operational involvement in fundraising, investor relations, or board reporting (preferred)
• Strong project management and organizational skills, with the ability to manage complex, cross-functional initiatives
• Excellent financial and business acumen; experience with budgets, forecasts, and KPIs
• Proven ability to build, lead, and develop teams
• Deep understanding of operational compliance, including legal, regulatory, quality management (QMS), and audit readiness
• Proven ability to build, lead, and develop teams across diverse operational functions
• Exceptional interpersonal and collaboration skills, with the ability to influence at all levels
• Outstanding verbal and written communication skills, including executive-level reporting and presentations
• Excellent verbal and written communication skills, including executive-level reporting and presentations
• Ability to thrive in a dynamic, fast-paced environment with shifting priorities
• Ability to drive cross-functional alignment and collaboration across scientific, operational, and corporate teams
• Strategic thinking and ability to scale operations in a growth-stage environment or commercialization-ready biotech environment
• Experience with contract development, procurement, and resource optimization
• Familiarity with QMS implementation, SOP development, and compliance frameworks in a biotech/pharma setting
• Financial fluency to support investor relations, board reporting, and fundraising activities
• Familiarity with technology-driven R&D environments including computational biology, machine learning
• Change management and process improvement capabilities
• Experience managing HCP engagement processes and ensuring compliance in clinical development