About the Role

SharkNinja is seeking a self driven Cost Engineer to support both Shark and Ninja new product lines by developing accurate “should be” cost models throughout the product development process. At SharkNinja, we pride ourselves on delivering affordable innovation, ease of use, and a strong focus on the consumer experience.

In this role, you will work closely with the AD and NPD teams to understand product architecture, manufacturing methods, and component selection in order to define the lowest possible cost to produce a product. This is an exciting opportunity for someone who is curious about how products are made, enjoys problem solving, and is motivated by identifying cost optimisation opportunities without compromising performance or consumer value.

What You Will Do

Coordinate product details to generate early ballpark cost estimates during the AD phase.
Develop and maintain should be cost models that reflect the latest product definition throughout prototype builds.
Review CBOMs from suppliers to validate cost assumptions and identify opportunities.
Deliver reports and presentation summaries highlighting key cost drivers and opportunities.
Review should be costs for consistency and accuracy across projects.
Generate critical component lists and work with Supply Chain teams to support supplier quoting activities.
Provide recommendations to product teams on design approaches that support lower cost manufacturing.
Support competitive product teardowns to understand materials, components, assembly methods, and feature implementation.
Prepare weekly project updates and participate in regular collaboration calls with the China cost engineering team.
Participate in product reviews, technical discussions, and hack sessions.

What You Will Bring

Bachelor’s degree in Mechanical Engineering or Industrial Engineering.
Experience in an engineering related field, preferably within product development.
Strong understanding of mechanical engineering fundamentals.
Experience working with consumer products or other high volume manufacturing environments.
Strong analytical and organisational skills with excellent attention to detail.
A proactive mindset and strong drive to identify the lowest achievable product cost.
Advanced Microsoft Excel skills.
Basic knowledge of plastics and metal manufacturing processes.
Ability to work flexibly and collaboratively in a fast paced environment.
Knowledge of SolidWorks or Creo.
Strong presentation and communication skills, with the ability to deliver clear summaries, insights, and recommendations.

The Product

In a rapidly evolving world, trust in AI depends on AI agents being grounded in fresh, verified real-world data. Search is the foundation that makes this possible.

We are building an agent-native search platform designed specifically for AI systems rather than human users. Our product provides programmatic, low-latency, and observable search APIs that AI agents use to retrieve, filter, and reason over real-world information at scale.

The Role

We are looking for a Senior Software Engineer to work on the runtime systems of a novel search engine tailored for agentic AI consumption.

In this role, you will focus on building low-latency, high-throughput systems that serve search queries in real time. You will work on the critical path of user-facing requests, where performance, predictability, and efficiency directly impact product quality. You will design and operate systems that handle thousands of requests per second under strict latency budgets, optimising every layer from request handling to data access and response assembly.

In this position, your responsibility will be to

• Design, implement, and operate core runtime services for serving search queries at scale
• Build and optimise request flows, including query processing, retrieval orchestration, and response assembly under strict latency budgets
• Develop systems that maintain performance and predictability under high load
• Optimise CPU, memory, and data access patterns in performance-critical paths
• Ensure reliability, observability, and predictability across production services
• Build well-tested systems with clear responsibilities and interaction contracts, while remaining flexible as architecture evolves
• Define and implement observability primitives, including structured logs, metrics, traces, and latency breakdowns
• Monitor throughput, latency, and resource usage, and drive improvements in performance and cost efficiency
• Collaborate with indexing and ML teams to integrate retrieval and ranking components, keeping ML logic decoupled from core system internals
• Support experimentation and iteration through controlled rollouts and rigorous benchmarking

You may be a good fit if you:

• Have 5+ years of experience as a software engineer working on production backend systems
• Have strong hands-on expertise in C++ or Rust in real-world, high-load services
• Have built and operated high-load, low-latency user-facing systems handling thousands of RPS under strict latency constraints
• Understand performance at a systems level — CPU, memory, networking, and data access
• Have operated your own code in production: deployed it, debugged incidents, and rolled back changes when necessary
• Think end-to-end about request flows rather than staying within isolated components
• Can balance correctness, latency, and development velocity, making pragmatic tradeoffs when scope or time requires
• Collaborate effectively across engineering, ML, and product teams, communicating clearly in cross-functional settings

Strong candidates may also have experience with:

• DBMS internals (open source or SaaS) and cloud infrastructure
• High-load web applications or large-scale APIs
• Performance-critical systems such as trading platforms or real-time data pipelines
• Low-level performance tuning and hardware-level optimisation
• Open-source contributions or active involvement in the engineering community
• Competitive programming or CTF participation
• SHAD or similar advanced technical programmes
• Conference talks or technical publications

We conduct coding interviews as part of the process.

Who we are

The role

The day-to-day

Own Production Pathway:

• Ensure the design is production-ready from the start: design for manufacturing, design for assembly, design for test. Every design decision should answer the question: "can a technician build unit #37 the same way unit #1 was built?"

• Own design documentation, version control, and assembly instructions. The design isn't done when the prototype works : it's done when someone who wasn't in the room can build it from the documentation.

• Support supplier selection and qualification: know which components are available at volume, which need custom development, and which are single-source risks

• Drive the transition from "engineer-built prototype" to "documented, repeatable, production-ready build" across 40 units

Drive Integration & Testing:

• Work alongside the engineering team to integrate every subsystem: flight controller (FC Board), edge compute, hydrophone array, satcom, network router, sensors

• Coordinate with the Software Tech Lead on the on-glider software stack

• Set the test strategy from bench through tank, and open-water sea trials. Move fast: first prototype in weeks/months. This is a high-pressure environment with tight timelines. We need someone who thrives under that kind of pressure.

• Build, test, learn, iterate

Break Design Deadlocks:

• Bring UUV systems experience to the decision table. When the team faces competing approaches, use your knowledge of what works underwater: what's been proven, what fails at depth, what scales to production: to define the most functional path forward based on the information available

• Not waiting for perfect data. Not deferring because someone has more experience. Assessing the options, making the call, explaining why, and moving on

• The team has deep expertise across mechanical, electrical, and embedded domains: your job is to ensure that expertise translates into decisions and forward momentum, not further analysis

Close the Design:

• Work with the existing technical team to drive Helsing's Maritime products from concept to something that can be built. Support and build on the architectural decisions already made while closing the remaining design gaps across all sub-systems (eg. hull, propulsion, variable buoyancy system, power, etc.)

• Own tradeoff calls that span mechanical, electrical, and embedded software boundaries. Be ready to explain the rationale clearly enough that the team buys in and moves forward.

• Know when a design is "good enough" to build and when it needs more iteration. Ensure the team doesn't get stuck in endless decision/refinement loops

• Think about scaled manufacturing from day one, just to prototyping
  
  

You should apply if you

• Built, integrated, tested, and deployed complex electromechanical systems. Not academic/simulated/paper.

• Systems-level decision-making across mechanical, electrical, and embedded software

• Technical decisiveness: closes tradeoffs, explains reasoning, moves on

• Pace and learning velocity: operates at startup speed, ramps up fast in new domains

• Collaborative communication: runs design reviews, manages technical output, gets buy-in

Note: We operate in an industry where women, as well as other minority groups, are systematically under-represented. We encourage you to apply even if you don’t meet all the listed qualifications; ability and impact cannot be summarised in a few bullet points.

Nice to Have

• Prototype-to-production experience

• Direct UUV, AUV, or underwater glider experience

• Buoyancy-driven platforms, underwater propulsion, or VBS

• Subsea comms (Iridium SBD), underwater acoustics, or edge compute (Jetson/similar)

• Defence or defence-adjacent programmes

• LARS and vessel operations

Join Helsing and work with world-leading experts in their fields 

• Helsing’s work is important. You’ll be directly contributing to the protection of democratic countries while balancing both ethical and geopolitical concerns

• The work is unique. We operate in a domain that has highly unusual technical requirements and constraints, and where robustness, safety, and ethical considerations are vital. You will face unique Engineering and AI challenges that make a meaningful impact in the world

• Our work frequently takes us right up to the state of the art in technical innovation, be it reinforcement learning, distributed systems, generative AI, or deployment infrastructure. The defence industry is entering the most exciting phase of the technological development curve. Advances in our field of world are not incremental: Helsing is part of, and often leading, historic leaps forward

• In our domain, success is a matter of order-of-magnitude improvements and novel capabilities. This means we take bets, aim high, and focus on big opportunities. Despite being a relatively young company, Helsing has already been selected for multiple significant government contracts

• We actively encourage healthy, proactive, and diverse debate internally about what we do and how we choose to do it. Teams and individual engineers are trusted (and encouraged) to practise responsible autonomy and critical thinking, and to focus on outcomes, not conformity. At Helsing you will have a say in how we (and you!) work, the opportunity to engage on what does and doesn’t work, and to take ownership of aspects of our culture that you care deeply about

What we offer

• Competitive salary and VSOP options

• Relocation support: up to €2,500 and 4 weeks temporary accommodation

• Learning: €500/£450 yearly allowance

• Health & wellness: gym membership and mental health support (Nilo.health)

• Social: regular company events and monthly social allowances

• Enhanced parental leave: 22 weeks fully paid for primary caregivers & 6 weeks for secondary caregivers

• Family support: 5 days of paid family emergency leave, 100% remote work option during pregnancy and phased return to work

• A hands-on onboarding program (affectionately labelled “Infraduction”), in which you will be building tooling and applications to be used across the company. This is your opportunity to learn our tech stack, explore the company, and learn how we get things done - all whilst working with other engineering teams from day one 

Helsing is an equal opportunities employer. We are committed to equal employment opportunity regardless of race, religion, sexual orientation, age, marital status, disability or gender identity. Please do not submit personal data revealing racial or ethnic origin, political opinions, religious or philosophical beliefs, trade union membership, data concerning your health, or data concerning your sexual orientation.

Cherry Ventures is supporting our portfolio with this hire

Founding Software Engineer Location: London/onsite

The Mission

We are building the Agentic Operating System for Consultants.

The $1 trillion consulting industry is powered by some of the world’s brightest minds, yet they remain trapped in manual, inefficient workflows - spreadsheet orchestration, slide-deck assembly, and fragmented data synthesis. We are moving the industry from "human-plus-tools" to autonomous agency.

Backed by a seed round from Cherry Ventures, Blue Lion, and the founders of QuantumBlack, our cap table includes angels from OpenAI, McKinsey, BCG, and Apple. We have the capital, the network, and the domain expertise - now seeking further engineering support to get there faster.

The Challenge

As one of our first engineers, you aren't just "writing code" - you are defining the technical DNA of the company. You will:

• Build Beyond the Chatbot: Design multi-step agentic workflows that move past simple RAG into reliable, enterprise-grade inference.
• Architect for Scale & Privacy: Build systems that can handle the rigorous data security requirements of Tier-1 financial and consulting firms.
• Own the Stack: Make foundational decisions on everything from our LLM orchestration layer to our deployment infrastructure.
• Interface with the Best: Work directly with technical & non-technical stakeholders across clients & advisory teams (OpenAI/McKinsey vets) to translate elite consulting tradecraft into code.

You Are a Fit If:

• You are a Product Engineer: You don’t need a 20-page PRD. You can take a vague user pain point from a design partner and ship a functional prototype by Friday.
• You have "Velocity as a Habit": You believe that in a seed-stage startup, speed is the only unfair advantage. You prefer shipping a 90% solution today over a perfect one next month.
• You are "T-Shaped": You are deeply technical in Python/Typescript and LLM frameworks (PydanticAI, LangGraph, etc.), but you also care about UI polish and user ergonomics.
• You have High Agency: When you hit a wall with an undocumented API or a hallucinating model, you find a way around it, over it, or through it.

Our Stack 

• Languages: Python, TypeScript
• AI/Data: Pydantic / LLM Frameworks, LiteLLM, ElasticSearch
• Infra: AWS, Terraform, PostgreSQL
• Frontend: React / Tailwind

Why Join Us?

• Real Ownership: Significant founding-level equity. You will own a meaningful piece of the company you are building.
• Elite Peer Group: Join a team that has lived this problem at the highest levels of global consulting and AI research.
• High Trust / Low Bureaucracy: We value clarity of thought and bias to action. No middle management, no pointless meetings - just building.

Job Title: Aseptic Pharmacy Technician

Banding: 5
Location: Bradford
Start Date: ASAP
End date: April
Hourly Rate: £19-£21
Working Hours: 37.5

Job Overview

We are seeking an experienced Aseptic Pharmacy Technician to join our team. The successful candidate will be responsible for the accurate preparation, assembly, and documentation of sterile medicinal products within an aseptic environment. This role ensures compliance with regulatory standards, aseptic technique, and quality assurance procedures to support safe and effective patient care.

Key Responsibilities

• Prepare sterile pharmaceutical products, including intravenous admixtures, cytotoxic drugs, parenteral nutrition, and other aseptic preparations, in accordance with approved procedures.
• Operate within controlled cleanroom environments, maintaining strict aseptic technique and contamination control.
• Follow Standard Operating Procedures (SOPs), Good Manufacturing Practice (GMP), and relevant regulatory guidelines.
• Accurately label, check, and document all aseptic preparations.
• Perform routine cleaning, environmental monitoring, and equipment checks within aseptic areas.
• Participate in validation, media fills, and competency assessments as required.
• Assist in stock control, storage, and rotation of raw materials and consumables used in aseptic services.
• Identify, report, and document deviations, incidents, and near-misses in line with quality systems.
• Work collaboratively with pharmacists, technicians, and other healthcare professionals to meet service demands.
• Support training of new staff and contribute to continuous quality improvement initiatives.

Qualifications and Experience

• Accredited Pharmacy Technician qualification (or equivalent).
• Registration with the relevant professional or regulatory body (where applicable).
• Previous experience working in an aseptic or cleanroom environment is highly desirable.
• Knowledge of aseptic techniques, GMP, and infection control principles.

Why Choose Pulse?

• Competitive pay rates and flexible working options.
• Dedicated consultant support throughout your assignment.
• Access to exclusive roles across the NHS and private sector.
• Free training and CPD opportunities to enhance your skills.

How to Apply

If you are interested in this role, please click Apply Now or contact Mimi Cowans at Pulse on Mimi.cowans@pulsejobs.com or phone 03308187532

Reasonable Adjustments

If you require any reasonable adjustments during the recruitment process, please let us know, and we will be happy to support you.

International Recruitment Notice

Please note: We are currently unable to offer sponsorship for this role. Applicants must have the right to work in the UK.

The Position

We are seeking an accomplished Account Executive to join our Enterprise team. This role focuses on developing strategic client relationships, driving revenue growth, and leading the entire sales process—from prospecting and consultative selling to contract negotiation and legal review.

This is a hybrid role- 1 day/week required in office.

Key Responsibilities

• Drive revenue growth through proactive business development, generating and managing your own client pipeline.
• Conduct consultative sales, engaging with senior executives to understand their needs and position GA's solutions effectively.
• Lead the creation and delivery of compelling sales presentations and proposals.
• Manage the end-to-end sales process, including negotiation, contract management, and legal review.
• Collaborate with internal teams, including Product, Marketing, Legal, Finance, and Delivery, to ensure client success.
• Maintain a deep understanding of GA’s products, services, pricing, and policies.
• Accurately maintain pipeline data and forecast sales performance using Salesforce.com.

Qualifications

• Minimum of 5 years of successful sales experience, ideally in enterprise sales.
• Proven ability to lead and close complex sales cycles, including contract negotiation and legal management.
• Experience engaging with senior decision-makers (SVP, C-suite) in large organizations.
• Track record of success with complex RFPs and strategic account management.
• Strong communication, interpersonal, and negotiation skills.
• Entrepreneurial mindset, with a proactive approach to business development.
• Proficiency with Salesforce.com for pipeline management and reporting.
• Ability to travel up to 20% of the time.
• A strong hunter, who is used to sourcing their own leads, cold calling, prospecting and using a tech stack including Salesforce, Outreach, and Sales Navigator.
• Demonstrable experience winning and expanding Public Sector Accounts valued at over £1m highly desirable.
• A background in tech education/upskilling sector experience highly desirable.
• Fluency in English (additional languages are a plus).

Core Competencies

• Business Insight
• Effective Communication
• Negotiation Skills
• Customer Focus
• Results Orientation
• Strategic Thinking
• Adaptability
• Problem-Solving

This position is ideal for a driven sales professional with a proven track record in complex enterprise sales and the ability to independently manage client relationships, from initial engagement through to contract negotiation and closure.

The Position

We are seeking an accomplished Account Director to join our Enterprise team. This role focuses on developing strategic client relationships, driving revenue growth, and leading the entire sales process—from prospecting and consultative selling to contract negotiation and legal review.

This is a hybrid role- 1 day/week required in office.

Key Responsibilities

• Drive revenue growth through proactive business development, generating and managing your own client pipeline.
• Conduct consultative sales, engaging with senior executives to understand their needs and position GA's solutions effectively.
• Lead the creation and delivery of compelling sales presentations and proposals.
• Manage the end-to-end sales process, including negotiation, contract management, and legal review.
• Collaborate with internal teams, including Product, Marketing, Legal, Finance, and Delivery, to ensure client success.
• Maintain a deep understanding of GA’s products, services, pricing, and policies.
• Accurately maintain pipeline data and forecast sales performance using Salesforce.com.

Qualifications

• Minimum of 5 years of successful sales experience, ideally in enterprise sales.
• Proven ability to lead and close complex sales cycles, including contract negotiation and legal management.
• Experience engaging with senior decision-makers (SVP, C-suite) in large organizations.
• Track record of success with complex RFPs and strategic account management.
• Strong communication, interpersonal, and negotiation skills.
• Entrepreneurial mindset, with a proactive approach to business development.
• Proficiency with Salesforce.com for pipeline management and reporting.
• Ability to travel up to 20% of the time.
• A strong hunter, who is used to sourcing their own leads, cold calling, prospecting and using a tech stack including Salesforce, Outreach, and Sales Navigator.
• Demonstrable experience winning and expanding Public Sector Accounts valued at over £1m highly desirable.
• A background in tech education/upskilling sector experience highly desirable.
• Fluency in English (additional languages are a plus).

Core Competencies

• Business Insight
• Effective Communication
• Negotiation Skills
• Customer Focus
• Results Orientation
• Strategic Thinking
• Adaptability
• Problem-Solving

This position is ideal for a driven sales professional with a proven track record in complex enterprise sales and the ability to independently manage client relationships, from initial engagement through to contract negotiation and closure.

Your impact

We are seeking a highly technical and collaborative Senior Chemistry, Manufacturing, and Controls Project Lead to drive the development and CMC strategy for our next-generation biologics and Antibody-Drug Conjugates (ADC) pipeline. This is a high impact position at the nexus of protein design and engineering, sophisticated linker-payload chemistry and complex regulatory sciences. The role requires a candidate who can navigate the unique challenges of multi-part drug substances and harmonise them into a stable, scalable therapeutic.

As the CMC Lead, you will serve as the technical expert for our diverse portfolio of computationally designed therapeutic candidates. This is a high-impact leadership role responsible for building the bridge between Isomorphic’s AI-driven discovery engine and the physical manufacturing of clinic-ready drugs.

You will design the CMC strategy for a variety of complex biologics and multi-specifics. You will oversee the end-to-end technical development, from cell line optimisation and sophisticated upstream/downstream processing to the precision chemistry required for advanced conjugation and assembly. We are looking for a visionary who thrives at the intersection of biology and chemistry, capable of navigating the unique CMC hurdles of next-generation modalities while ensuring a robust, scalable path to the clinic:

What you will do

• Design and oversee end-to-end manufacturing frameworks for a diverse portfolio of novel scaffolds and functionalized antibodies. This includes orchestrating cell line development, advanced upstream/downstream biologics processing, and the precision molecular assembly or conjugation steps required for next-generation therapeutic formats.
• Lead the optimization of site-specific modification and coupling chemistries (e.g., conventional and novel conjugation). You will drive strategies to achieve precise stoichiometry (including Drug-to-Antibody Ratios) and structural homogeneity while minimizing product-related impurities and "off-target" modifications.
• Lead the selection and technical oversight of global Contract Development and Manufacturing Organizations. You will manage complex tech transfers, audit Master Batch Records, and troubleshoot manufacturing deviations for both the biologic intermediates and the final multi-component drug products.
• Define the Analytical Target Profile for designed complex molecules. You will ensure the structural integrity, folding, and stability of integrated linkers, payloads, or auxiliary domains under physiological and accelerated stress conditions.
• Act as the primary author for CMC sections of global regulatory filings (IND/IMPD/BLA). You will develop and defend the control strategy for both the primary biologic and any high-potency or chemically synthesized components, ensuring alignment with global health authority expectations for novel modalities.

Skills and qualifications 

Essential:

• PhD or MSc in Biochemistry, Chemical Engineering, Chemistry, or a related biopharmaceutical field.
• 8+ years (or 5+ for high-growth) of professional experience in biologics CMC, with a proven track record of moving complex modalities from late-stage discovery into clinical manufacturing.
• Experience with a diverse range of next-gen scaffolds, such as bispecific antibodies, nanobodies (VHH), or cytotoxic and non-cytotoxic/novel payload delivery systems.
• Direct, hands-on experience in the development, scale-up, or manufacturing of Antibody-Drug Conjugates (ADCs) or other chemically modified biologics.
• Deep knowledge of analytical techniques required for multi-component molecules, including Drug-to-Antibody Ratio (DAR) determination and advanced peptide mapping/MS-based characterization.
• Strong practical knowledge of cGMP and global regulatory guidelines (FDA/EMA), specifically as they apply to combination products and biotechnological intermediates.

Nice to have:

• Experience of working with ML models for biologics design
• Experience of developing or using AI tools (LLM) to accelerate CMC processes including reporting.