QuantHealth is an AI startup revolutionizing drug development and clinical trials. Our cutting-edge clinical trial simulator can run thousands of trials in parallel to de-risk and optimize real-world clinical trials. Powered by a unique dataset of over 350M patients and 100K drugs, our platform helps drastically reduce drug development costs and timelines. We’re venture-backed, based in Israel, and work with top-tier pharma companies across Europe and the US. 

We are looking for a Senior Back End Engineer (API & Agentic AI) to play a key role in the evolution of QuantHealth’s backend architecture and emerging AI platform capabilities. This role will contribute significantly to the transition from a monolithic application to a multi-service backend platform, while also helping design and implement the backend foundations for agentic AI systems used across our product.

You will work on core backend services, API design, and distributed system concerns, and collaborate closely with full stack, product, data science, and security teams to build scalable, secure, and well-observed services that support both human-facing workflows and autonomous AI agents.

What You’ll Do

Backend & Platform Architecture

• Contribute to the design and implementation of a multi-service backend architecture

• Design, build, and maintain robust, well-documented APIs for internal and external consumers

• Help define backend standards that support both traditional SaaS workflows and AI-driven, agent-based execution

• Collaborate on architectural decisions and provide technical guidance within the engineering team

Agentic AI Enablement

• Design backend primitives and services that support agentic AI systems (e.g., task execution, state management, orchestration, tool invocation)

• Build APIs and infrastructure that allow AI agents to safely interact with internal services, data, and external systems

• Implement guardrails for agent execution, including authorization boundaries, auditability, rate limits, and failure handling

• Partner with data science and ML engineers to productionize AI workflows in a reliable, observable, and secure way

Backend Best Practices & Reliability

• Implement and improve backend best practices, including:

  • Authentication and authorization (token-based auth, RBAC, service-to-service auth)

  • Idempotency and safe retry mechanisms

  • Consistent error modeling and API contracts

  • Input validation and schema enforcement

  • API versioning and backward compatibility

• Ensure backend services follow strong networking and security principles

• Help establish and maintain observability standards (logging, metrics, tracing)

• Write high-quality, well-tested TypeScript code

What We’re Looking For

• 7+ years of professional software engineering experience, primarily focused on backend systems

• Strong expertise in TypeScript for server-side development

• Proven experience designing and implementing APIs for complex systems

• Experience with Nest.js or another major TypeScript backend framework (e.g., AdonisJS, Express, Fastify, Koa)

• Solid understanding of:

  • HTTP and networking fundamentals

  • API security and authentication/authorization patterns

  • Reliability concerns in distributed systems

• Experience with:

  • API documentation (OpenAPI / Swagger)

  • Testing strategies (unit, integration, API tests)

  • Validation and contract-driven development

• A pragmatic, ownership-oriented mindset with strong engineering judgment

• Comfort working in systems that mix deterministic software with probabilistic AI components

Nice to Have

• Experience participating in monolith-to-services or modularization efforts

• Experience supporting external, customer-facing APIs

• Experience designing systems that support AI agents, workflows, or automation platforms

• Familiarity with LLM tooling concepts (tools/functions, agent loops, structured outputs)

• Experience with Effect

• Familiarity with healthcare, life sciences, or regulated environments

• Experience with cloud-native deployments and production observability tooling

Why QuantHealth

• Work on technically deep problems at the intersection of backend systems and AI in healthcare

• Help shape both a scalable backend platform and the foundations of agentic AI capabilities

• Collaborate with a thoughtful, high-caliber engineering team

• Competitive compensation and opportunities for growth

About LightForce Orthodontics

LightForce is leading the digital transformation of orthodontics and redefining the standard of care for patients. Our fully digital, 3D-printed orthodontic platform increases practice efficiency, improves clinical consistency, and enables more predictable treatment outcomes.Unlike traditional stock brackets, LightForce delivers fully customized, patient-specific brackets paired with AI-driven treatment planning—optimizing outcomes at scale. With recent advancements unlocking the next phase of digital orthodontics, LightForce continues to push the boundaries of what’s possible in personalized care. Learn more at www.lf.co

Description

LightForce Orthodontics is seeking a talented Software Engineer to join our Operations-facing software development teams, who is passionate about designing and implementing elegant solutions to complex issues in the Digital & Physical Manufacturing spaces. As a Software Engineer, you will join our rapidly expanding team to design, implement, test and maintain features critical to the success of our manufacturing automation and technician facing web application. You will work closely with Product Management, key stakeholders and a small scrum team to help scale our rapidly growing product.

LightForce Orthodontics hires committed, self-motivated employees and then gives them the freedom and flexibility to do great work. You should feel comfortable with learning new technologies, proposing solutions to issues, and breaking down project plans into actionable steps within a development team. You will help to grow a fantastic, industry-changing tech company, to advance the orthodontic profession, and to provide positive health benefits to patients.

Essential Duties and Responsibilities

• Full-stack software development
• Implement new features, fix bugs, and participate in all scrum ceremonies
• Collaborate with other developers via code reviews and discussions
• Drive technical projects in an innovative and fast-paced environment

Education and Experience

• BS in Computer Science, Software Engineering, or a related quantitative field
• 5+ years of experience developing and debugging with languages/frameworks such as Typescript, Node.js, Express.js
• Experience architecting, developing and maintaining a SaaS based infrastructure in AWS (Lambda, Step Functions, API Gateway, RDS, ECS/EC2)
• Experience with PostgreSQL or similar database technologies

Required Qualifications

• Conscientious team member and independent worker
• Experienced working within a scrum/agile organization
• Effectively communicates inside and outside of engineering

Preferred Qualifications

• Experience with infrastructure as code (Serverless, Terraform)
• Experience with 3D technologies (Three.js), manufacturing automation, or medical device software.
• Angular knowledge 

Physical Demands

• Requires the ability to use hands, and reach with hands and arms
• Requires the ability to see, listen, and speak

Work Environment

• Work is generally performed in an open office, sedentary position.

To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.

LightForce Orthodontics is an Equal Opportunity/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, gender, age, national origin, disability, Protected Veteran status, sexual orientation, or any other characteristic protected by federal, state, or local law.