The mission of Speechify is to make sure that reading is never a barrier to learning.

Over 50 million people use Speechify’s text-to-speech products to turn whatever they’re reading – PDFs, books, Google Docs, news articles, websites – into audio, so they can read faster, read more, and remember more. Speechify’s text-to-speech reading products include its iOS app, Android App, Mac App, Chrome Extension, and Web App. Google recently named Speechify the Chrome Extension of the Year and Apple named Speechify its 2025 Design Award winner for Inclusivity.  

Today, nearly 200 people around the globe work on Speechify in a 100% distributed setting – Speechify has no office. These include frontend and backend engineers, AI research scientists, and others from Amazon, Microsoft, and Google, leading PhD programs like Stanford, high growth startups like Stripe, Vercel, Bolt, and many founders of their own companies.

Overview

We're looking to hire for our Data side of our AI team at Speechify. This role is responsible for all aspects of data collection to support our model training operations. We are able to build high-quality datasets at petabyte-scale and low cost through a tight integration of infrastructure, engineering, and research work. We are looking for a skilled Software Engineer to join us.

What You’ll Do

• Be scrappy to find new sources of audio data and bring it into our ingestion pipeline
• Operate and extend the cloud infrastructure for our ingestion pipeline, currently running on GCP and managed with Terraform.
• Collaborate closely with our Scientists to shift the cost/throughput/quality frontier, delivering richer data at bigger scale and lower cost to power our next-generation models.
• Collaborate with others on the AI Team and Speechify Leadership to craft the AI Team’s dataset roadmap to power Speechify’s next-generation consumer and enterprise products.

An Ideal Candidate Should Have

• BS/MS/PhD in Computer Science or a related field.
• 5+ years of industry experience in software development.
• Proficiency with bash/Python scripting in Linux environments
• Proficiency in Docker and Infrastructure-as-Code concepts and professional experience with at least one major Cloud Provider (we use GCP)
• Experience with web crawlers, large-scale data processing workflows is a plus
• Ability to handle multiple tasks and adapt to changing priorities.
• Strong communication skills, both written and verbal.

What we offer

• A fast-growing environment where you can help shape the company and product.
• An entrepreneurial-minded team that supports risk, intuition, and hustle.
• A hands-off management approach so you can focus and do your best work.
• An opportunity to make a big impact in a transformative industry.
• Competitive salaries, a friendly and laid-back atmosphere, and a commitment to building a great asynchronous culture.
• Opportunity to work on a life-changing product that millions of people use.
• Build products that directly impact and support people with learning differences like dyslexia, ADD, low vision, concussions, autism, and more.
• Work in one of the fastest-growing sectors of tech, the intersection of artificial intelligence and audio.

Think you’re a good fit for this job? 

Tell us more about yourself and why you're interested in the role when you apply.
And don’t forget to include links to your portfolio and LinkedIn.

Not looking but know someone who would make a great fit? 

Refer them! 

Speechify is committed to a diverse and inclusive workplace. 

Speechify does not discriminate on the basis of race, national origin, gender, gender identity, sexual orientation, protected veteran status, disability, age, or other legally protected status.

Role

The Software & Data Science team at Vivodyne tackles some of the hardest problems at the intersection of human biology, large-scale data, and machine learning using uniquely rich imaging and multi-omics datasets from lab-grown human tissues.

We are expanding our capabilities to generate high-throughput -omics data across automated human tissue models, with a primary focus on single-cell and bulk transcriptomics, secretomics, and proteomics. We're looking for a Bioinformatician who can develop new analytical methods and build robust infrastructure to support them at scale.

You will define how we process, store, integrate, and interpret biological datasets, making foundational decisions that shape the long-term utility of our data for internal research, AI/ML model development, and external partners. This means owning both the science (what question does this analysis answer, and how defensible is the conclusion?) and the engineering (does this pipeline run reliably at scale, and can someone else extend it?).

This is a high-impact, cross-functional role. You'll sit within the Software & Data Science organization and collaborate daily with experimental biologists, AI/ML researchers, software engineers, and client-facing teams.

This is a full-time, onsite role in San Francisco.

Responsibilities

Develop and Own Analytical Methods

• Design, implement, and critically evaluate computational approaches for scRNA-seq, bulk RNA-seq, secretomics, and proteomics data including QC, normalization, batch correction, dimensionality reduction, clustering, differential expression, trajectory analysis, and multi-dataset integration.
• Go beyond applying standard tools: develop or adapt methods for perturbation modeling, causal inference, network reconstruction, ligand-receptor inference, and multi-omics integration as the science demands.
• Select and standardize tooling based on rigorous benchmarking, not convention. Challenge default choices when the data or use-case warrants it.

Build Scalable, Production-Grade Pipelines

• Architect end-to-end analysis workflows in Python and/or R using modern workflow orchestration (Nextflow, Snakemake, or equivalent) that are reproducible, version-controlled, and designed to run at the scale of tens to hundreds of thousands of samples.
• Partner with software and data engineers to productionize pipelines, ensure robust data ingestion and storage, and contribute to decisions on biological data architecture (storage formats, schema design, long-term data usability).
• Write well-documented, testable code that other engineers and scientists can run, review, and extend.

Drive Biological Insight and Interpretation

• Own dataset analysis to answer biological and client-driven questions with rigor. Ground conclusions in the limits of the data and clearly communicate what can and cannot be concluded with confidence.
• Partner with experimental biologists to frame the most relevant biological questions, design analyses, and recommend experiments and data-generation strategies to fill key gaps.
• Produce publication-quality figures, internal reports, and partner-facing deliverables that are decision-useful.

Shape Data Strategy

• Help define benchmarking strategies for internal tissue model development.
• Proactively identify opportunities to leverage internal and public datasets to accelerate scientific progress.
• Contribute to decisions around data standards, comparability, and the integration of omics features into downstream ML models and AI workflows.

Communicate Across Functions

• Translate complex multi-omic analyses into clear insights for biologists, AI/ML researchers, software engineers, and non-technical stakeholders.
• Tailor depth and framing to the audience while maintaining scientific rigor.

Requirements and Expectations

Technical Expertise

• Ph.D. in Computational Biology, Bioinformatics, Genomics, Systems Biology, Biostatistics, or a related quantitative field with deep focus on transcriptomics and/or proteomics.
• 2–5 years of post-PhD experience; some industry experience strongly preferred.
• Strong, hands-on proficiency in Python for bioinformatics (Scanpy and the broader scverse ecosystem in particular) with the judgment to know when existing tools are insufficient and the skill to build alternatives. Familiarity with R-based workflows (Seurat, Bioconductor, Monocle) is valued as evidence of breadth, but Python is the production language.
• Deep experience with scRNA-seq datasets and workflows, including QC, batch correction, clustering, differential expression, annotation, and integration across experiments.
• Experience with proteomics or secretomics analysis (Olink or similar high-dimensional panels), including normalization and cross-modality integration with transcriptomic profiles.
• Comfort in a Unix/Linux environment with standard dev tools (git, containers, CI/CD); experience with cloud environments (AWS) and workflow managers is a strong plus.
• Familiarity with data infrastructure for large-scale biological data (e.g., AnnData/H5AD, TileDB-SOMA, or similar) is a plus.

Problem Solving & Ownership

• Ability to independently structure and execute complex analytical projects from ambiguous initial questions to concrete, reviewable outputs.
• Strong biological intuition for distinguishing meaningful signal from artifact and the discipline to validate before interpreting.
• Comfortable navigating ambiguity in a fast-moving startup; can prioritize, make trade-offs, and hit agreed timelines.

Collaboration & Communication

• Excellent written and verbal communication; able to explain computational methods and biological implications to biologists, engineers, and non-technical stakeholders.
• Proven ability to collaborate across disciplines.

Innovation & Leadership

• Track record of taking omics analyses from raw data to figures/tables suitable for publications, reports, or decision meetings.
• Demonstrated ability to manage multiple analyses in parallel and ship work on predictable timelines.
• History of method development or meaningful adaptation of existing methods to novel data types or experimental designs.

Preferred Qualifications

• Experience with multi-modal data integration (e.g., combining imaging, transcriptomics, and proteomics features).
• Background in drug discovery, toxicology, or translational research where multi-omic data inform therapeutic decisions.
• Experience with representation learning or ML for biological data (embeddings for cells, genes, or proteins), especially in collaboration with ML specialists.
• Familiarity with organoids, primary tissues, or organ-on-chip systems.

Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.