Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

Job Summary:

As a key member of the cross-functional Development Team responsible for providing regulatory writing expertise and leadership to formulate the writing strategy for key regulatory documents for submission. The Sr. Director, Head of Regulatory & Medical Writing will be responsible for providing guidance to the medical and or regulatory writing group (contractors and internal writers) assigned to deliverables and ensuring appropriate work allocation and document preparation.; will also provide review and substantive editing of documents to ensure delivery of high-quality documents. This individual will work effectively with many other functional groups, including with Clinical Scientist(s), Medical Monitors, Regulatory and other functions as applicable, and collaborate with clinical medical writing as applicable to ensure scientific excellence in the execution of clinical trials. The Head of Regulatory Writing will build a medical writing group internally when appropriate.

Reporting to the SVP, Head of Regulatory Affairs, this role will be responsible for the regulatory writing & medical writing deliverables of assigned project(s), in accordance with the agreed timelines and quality standards.

Responsibilities:

• Ensure appropriate allocation of internal and external resources needed for all regulatory writing deliverables.
• Hire and manage medical writers internally and manage external medical writing contractors.
• Forecasting and maintaining budget for the regulatory writing team.
• Assess efficiencies, help identify areas of improvement and initiate improvement processes.
• Coordinate, author and edit documents used to support clinical trial conduct and reporting including but not limited to:
• Clinical study protocols and clinical protocol amendments (in partnership with Clinical Science/Clinical Development)
• Clinical study reports
• Investigator’s brochures and annual updates
• IND submissions and annual reports
• Lay-person summary
• Integrated summary reports
• Clinical, Nonclinical and Multidisciplinary Information Amendments
• NDA, BLA, MAA, (e)CTD submissions
• Risk Management Plans
• Health Authority responses
• Briefing Documents, ODDs, BTDs/PRIME, FTD etc
• Participate in relevant subteam(s) and ensure effective planning and management of timelines for all components of assigned documents across all projects.
• Participate in document strategy sessions, including messaging, document flow, logic, and consistency for assigned projects.
• Support and develop deliverables required for global transparency and disclosure requirements (e.g., plain language lay summary, applicable redactions to regulatory documents subject to EU posting regulations and results for EU CTR).Partner with Biometrics in developing standard TFLs and in text tables for deliverables as applicable
• Maintain and support developing and reviewing standard processes and templates.
• Review and edit documents as required.
• Work effectively and lead in cross-functional working groups.

Qualifications:

• Candidates must have a BS with 15+ years, or MS or other advanced science degree (e.g.: RN, NP, MSN, PharmD, PhD, MD) with 10+ years of experience in oncology clinical research experience as a clinical or regulatory medical writer within the pharmaceutical/biotech industry.
• Prior experience leading a regulatory writing group
• Experience writing/leading the writing of critical clinical documents in major regulatory filings (NDA, BLA, MAA).
• Proficiency in the use and understanding of computer software e.g. word processing, graphics, reference manager, document management systems.
• Familiarity with all phases of drug development processes (discovery to market), clinical study protocol design, CTA/IND submissions, investigator’s brochures and clinical study data collection and results reporting.
• Advanced knowledge of routine document content preparation, including the use of style guides, medical dictionaries, and regulatory guidance documents and templates.
• Experience writing, at a minimum, protocols (Phase 1-3, in oncology), investigator’s brochures, clinical study reports, Health Authority briefing packages, and Health Authority responses. Experience with Pediatric Investigational Plans (PIPs) is preferred.
• Advanced understanding/knowledge of regulatory requirements and drug development processes, Good Clinical Practice (GCP), regulatory requirements and guidelines associated with regulatory documents (e.g., protocols, investigator brochures, and clinical study reports).
• Ability to interpret and summarize complex tabular and graphical data presentations.
• Strong organization, documentation and communication skills with an ability to multitask.
• Adaptable / flexible, willing and able to adjust to multiple demands and shifting priorities; ability to meet day-to-day challenges with confidence and professionalism.
• Detailed knowledge of GCP, ICH Guidelines and current US FDA regulations.

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/).

Position Title:  

Associate Director, Regulatory Affairs (Strategy, Hematology Oncology)

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

Job Summary:

Nurix Therapeutics, Inc. is seeking a Manager/Sr. Manager/Associate Director, Regulatory Affairs (Strategy, Hematology Oncology) to join the Regulatory team.  The successful candidate will be a core member of the Regulatory team and will be responsible for helping build and execute on global regulatory strategy, objectives, policies and programs pertaining to development and future marketing of products for guiding and executing upon regulatory strategy of compliant, high quality, nonclinical and clinical submissions and interactions in support of early development, registration and life cycle management activities. This includes supporting regulatory activities to enable clinical development plans and studies, working cross-functionally across the organization.

Responsibilities:

• Provides regulatory strategic direction and support for assigned global development programs/development program activities
• Assists Sr. Regulatory Affairs staff with their development program activities and deliverables
• Designs and implements regulatory strategies with Regulatory Affairs staff to obtain and maintain product investigative and marketing applications for assigned programs, as well as their life cycle management
• Acts as regulatory representative on early and/or late phase clinical studies, ensuring compliant execution of trials
• Strong competency in understanding regulatory requirements and emerging regulatory landscapes associated with US and global regulatory authorities
• Experienced in responding to inquiries from global regulatory authorities as well as the preparation and conduct of meetings with global regulatory authorities
• Assist in the preparation and maintenance of Annual Reports, Development Safety Update Reports (DSURs), Investigator’s Brochures and other documents required for INDs, CTAs, NDAs and other related regulatory development and marketing applications
• Assist in the cataloging and maintenance of regulatory application submissions
• Conduct research and stay up-to-date on regulatory requirements and changes
• Collaborate with cross-functional teams to ensure product compliance throughout the development lifecycle
• Monitor and assess regulatory risks and develop mitigation strategies
• Oversee quality assurance processes to ensure compliance with regulatory standards
• Review SOPs pertaining to Regulatory
• Works strategically with all regulatory functions to develop detailed, actionable submission plans, tracks major submission deliverables, and ensures consistent management submission documents, health authority communications, and all other regulatory information supporting Nurix’s investigational and marketing applications
• Plays an essential part in defining requirements for, implementing, and supporting future systems and tools to be employed by Nurix in the areas of document management, submission content planning, and regulatory information management
• Tracks the status of major deliverables for regulatory submissions (e.g., study reports, summary documents, labeling) along with their dependencies
• Develops and maintains submission plan templates to ensure Nurix regulatory submissions are consistently planned and executed across programs
• Participates in cross-functional process initiatives impacting regulatory submission processes and systems
• Manages consultants and contractors as needed

Experience and Skills:

• Bachelor's degree in life-sciences or related scientific discipline; advanced degree preferred Manager:
• Must have minimum of 8 years in Regulatory affairs strategy
• Strong demonstration of knowledge of drug development, FDA, EMA and ICH guidelines and regulations
• Experience providing hands-on support for planning clinical trial and marketing applications to health authorities including but not limited to FDA, EMA
• Ability to read, analyze and interpret scientific and technical information, as well as regulatory
• Ability to understand and explain detailed regulatory affairs and compliance programs and/or to effectively present information to senior regulatory management, other departments or external
• Ability to comply with changing regulatory
• Proven track record of supporting Regulatory affairs in the planning and execution of major filings and ongoing maintenance of clinical trial and marketing applications
• Strong project management and critical thinking skills
• Experience applying project management techniques and tools (e.g., MS Project, Smartsheet, Excel trackers) to the planning and execution of regulatory submissions
• Excellent organizational and communication skills, both written and verbal
• Ability to work independently as well as part of a team environment
• Positive attitude, energetic and proactive
• Proven ability to manage multiple projects, identify and resolve regulatory issues
• Strong interpersonal skills and the ability to effectively work with others

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix. By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/).

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

Position:  Biosample Manager 

Nurix Therapeutics, Inc. is seeking a Biosample Manager to join the Clinical Operations team. This is an onsite role. This individual will work cross functionally, with both internal and external stakeholders, to plan, coordinate, and oversee all operational activities required to manage the lifecycle of the clinical biosamples and support translational research.

Responsibilities:

Study Management

• Provide guidance during protocol and informed consent form development to ensure logistical feasibility of biosample handling, alignment with planned analyses and ICH/GCP compliance
• Participate in the CRF development process to ensure that biosample information is appropriately captured for sample tracking and reconciliation purposes
• Serve as the functional lead as a member of the Clinical Study Teams and provide regular biosample metrics/trends and status updates
• Partner with cross-functional teams to ensure timely delivery of biosample data to meet publication and study goals

Biosample and Vendor Management

• Provides operational leadership on vendor and sample management activities, including design of central lab specifications at study start or amendments
• Oversee kit design, sample processing, and sample logistics to ensure that the investigator sites can meet the sample handling needs of the study
• Plan, coordinate and oversee sample shipments and query resolution at laboratory vendors
• Manage the sample management system to track the life cycle of the samples, identify trends and gaps, and support sample reconciliation
• Provide training and guidance to the investigator sites and study monitors for biosample collection, handling and shipment
• Manage laboratory vendors, overseeing vendor selection, technology transfers, budgets, contract management, and data management
• Develop and maintain biosample operations SOPs and WPs

Qualifications:

• B.S. in biological sciences with 8+ years of relevant industry experience
• Knowledge of FDA, ICH/GCP, and GDPR regulations and guidelines
• Proven track record of sample management, data management and vendor management skills
• Developed central lab specifications and logistics for global studies at study start or protocol amendments with cross-functional collaboration
• Ability to develop and manage workflows and data sets
• Proficiency in MS Office including with advance Excel skills
• Good initiative and ability to work independently
• Ability to work in a fast-paced environment
• Excellent written and interpersonal communication skills
• Detail oriented with the ability to manage multiple competing priorities
• Effective team player and ability to collaborate with cross functional clinical study teams
• Onsite role 

Salary Range:  140K - 180K plus equity and bonus 

Nurix is an Equal Opportunity Employer offering a competitive salary and benefits package. Applicants should be legally entitled to work for any employer in the US.Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/). 

Scientist I, In Vivo Pharmacology 

 Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

Nurix is seeking a motivated and detail‑oriented Scientist I/II to join our Preclinical Pharmacology group with a primary focus on in vivo pharmacology and pharmacokinetics (PKPD) and inflammatory and autoimmune diseases.

The position

We are seeking a highly skilled and motivated in vivo pharmacologist to lead efforts in inflammation. The ideal candidate will have expertise in small molecule PK/PD studies, inflammatory disease models, and immune cell profiling by flow cytometry. This hands‑on Scientist I/II role focuses on rodent models of inflammatory skin disease to characterize PK, PD, efficacy, and safety of therapeutic candidates. The candidate will establish new disease models in house. The scientist will design and execute skin inflammation studies, dose, collect and process blood, skin, and lymphoid tissues, and support ex vivo/in vitro immunology and molecular assays. The position is bench and vivarium based, requiring strong animal‑handling skills, experience with AD‑ and psoriasis‑like models, rigorous electronic documentation, and close collaboration with Discovery Research, DMPK, and other cross‑functional teams. At the Scientist II level, the individual will also be responsible for selected models or workflows, troubleshoot, implement technical improvements, and mentor junior staff.

This is an excellent opportunity for a hands‑on in vivo scientist who enjoys bench work and wants to contribute directly to the generation of high‑quality data that drive target validation, lead optimization, and clinical candidate selection.

Qualifications

Job level will be commensurate with experience.

• Ph.D. in pharmacology, cancer biology, immunology, or related field with relevant post-doctoral or industry experience; or B.S./M.S. in Pharmacology, Pharmaceutical Sciences, Biology, or related discipline
• Experience Sci I: typically ≥1 year (Ph.D.), ≥4 years (M.S.), or ≥8 years (B.S.)
• Experience Sci II: typically ≥4 year (Ph.D.), ≥8 years (M.S.), or ≥12 years (B.S.)
• Knowledge of PK/PD concepts and basic pharmacokinetic analysis
• Excellent hands-on skills, including IV, PO, intradermal, and topical dosing, and blood/tissue collection
• Experience with inflammation, immunology, or dermatology disease models (e.g., MC903/AD, imiquimod psoriasis, contact hypersensitivity, PCA, pruritus/itch, CIA, EAE) and associated clinical scoring.
• Experience with PD biomarker assessment (e.g., ELISA/multiplex cytokines, Western blot, flow cytometry, qPCR); multiparameter flow cytometry for immune cell phenotyping, ex vivo stimulation assays, cytokine release, or proliferation assays is preferred.
• Experience working with electronic lab notebooks and data analysis/graphing software (e.g., Excel, Prism, FlowJo or similar).
• Excellent communication and presentation skills, with strong interpersonal skills and the ability to work productively in a highly dynamic, cross-functional environment.

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative; solutions and results-oriented focus
• Strong scientific curiosity and initiative; hands-on and resourceful
• Self-driven and enthusiastic with the ability to thrive in a dynamic environment

Location: Brisbane, CA

Salary Range:

Scientist I:        $127,216.00 – $144,156.00

 Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/). 

Role

The Software & Data Science team at Vivodyne tackles some of the hardest problems at the intersection of human biology, large-scale data, and machine learning using uniquely rich imaging and multi-omics datasets from lab-grown human tissues.

We are expanding our capabilities to generate high-throughput -omics data across automated human tissue models, with a primary focus on single-cell and bulk transcriptomics, secretomics, and proteomics. We're looking for a Bioinformatician who can develop new analytical methods and build robust infrastructure to support them at scale.

You will define how we process, store, integrate, and interpret biological datasets, making foundational decisions that shape the long-term utility of our data for internal research, AI/ML model development, and external partners. This means owning both the science (what question does this analysis answer, and how defensible is the conclusion?) and the engineering (does this pipeline run reliably at scale, and can someone else extend it?).

This is a high-impact, cross-functional role. You'll sit within the Software & Data Science organization and collaborate daily with experimental biologists, AI/ML researchers, software engineers, and client-facing teams.

This is a full-time, onsite role in San Francisco.

Responsibilities

Develop and Own Analytical Methods

• Design, implement, and critically evaluate computational approaches for scRNA-seq, bulk RNA-seq, secretomics, and proteomics data including QC, normalization, batch correction, dimensionality reduction, clustering, differential expression, trajectory analysis, and multi-dataset integration.
• Go beyond applying standard tools: develop or adapt methods for perturbation modeling, causal inference, network reconstruction, ligand-receptor inference, and multi-omics integration as the science demands.
• Select and standardize tooling based on rigorous benchmarking, not convention. Challenge default choices when the data or use-case warrants it.

Build Scalable, Production-Grade Pipelines

• Architect end-to-end analysis workflows in Python and/or R using modern workflow orchestration (Nextflow, Snakemake, or equivalent) that are reproducible, version-controlled, and designed to run at the scale of tens to hundreds of thousands of samples.
• Partner with software and data engineers to productionize pipelines, ensure robust data ingestion and storage, and contribute to decisions on biological data architecture (storage formats, schema design, long-term data usability).
• Write well-documented, testable code that other engineers and scientists can run, review, and extend.

Drive Biological Insight and Interpretation

• Own dataset analysis to answer biological and client-driven questions with rigor. Ground conclusions in the limits of the data and clearly communicate what can and cannot be concluded with confidence.
• Partner with experimental biologists to frame the most relevant biological questions, design analyses, and recommend experiments and data-generation strategies to fill key gaps.
• Produce publication-quality figures, internal reports, and partner-facing deliverables that are decision-useful.

Shape Data Strategy

• Help define benchmarking strategies for internal tissue model development.
• Proactively identify opportunities to leverage internal and public datasets to accelerate scientific progress.
• Contribute to decisions around data standards, comparability, and the integration of omics features into downstream ML models and AI workflows.

Communicate Across Functions

• Translate complex multi-omic analyses into clear insights for biologists, AI/ML researchers, software engineers, and non-technical stakeholders.
• Tailor depth and framing to the audience while maintaining scientific rigor.

Requirements and Expectations

Technical Expertise

• Ph.D. in Computational Biology, Bioinformatics, Genomics, Systems Biology, Biostatistics, or a related quantitative field with deep focus on transcriptomics and/or proteomics.
• 2–5 years of post-PhD experience; some industry experience strongly preferred.
• Strong, hands-on proficiency in Python for bioinformatics (Scanpy and the broader scverse ecosystem in particular) with the judgment to know when existing tools are insufficient and the skill to build alternatives. Familiarity with R-based workflows (Seurat, Bioconductor, Monocle) is valued as evidence of breadth, but Python is the production language.
• Deep experience with scRNA-seq datasets and workflows, including QC, batch correction, clustering, differential expression, annotation, and integration across experiments.
• Experience with proteomics or secretomics analysis (Olink or similar high-dimensional panels), including normalization and cross-modality integration with transcriptomic profiles.
• Comfort in a Unix/Linux environment with standard dev tools (git, containers, CI/CD); experience with cloud environments (AWS) and workflow managers is a strong plus.
• Familiarity with data infrastructure for large-scale biological data (e.g., AnnData/H5AD, TileDB-SOMA, or similar) is a plus.

Problem Solving & Ownership

• Ability to independently structure and execute complex analytical projects from ambiguous initial questions to concrete, reviewable outputs.
• Strong biological intuition for distinguishing meaningful signal from artifact and the discipline to validate before interpreting.
• Comfortable navigating ambiguity in a fast-moving startup; can prioritize, make trade-offs, and hit agreed timelines.

Collaboration & Communication

• Excellent written and verbal communication; able to explain computational methods and biological implications to biologists, engineers, and non-technical stakeholders.
• Proven ability to collaborate across disciplines.

Innovation & Leadership

• Track record of taking omics analyses from raw data to figures/tables suitable for publications, reports, or decision meetings.
• Demonstrated ability to manage multiple analyses in parallel and ship work on predictable timelines.
• History of method development or meaningful adaptation of existing methods to novel data types or experimental designs.

Preferred Qualifications

• Experience with multi-modal data integration (e.g., combining imaging, transcriptomics, and proteomics features).
• Background in drug discovery, toxicology, or translational research where multi-omic data inform therapeutic decisions.
• Experience with representation learning or ML for biological data (embeddings for cells, genes, or proteins), especially in collaboration with ML specialists.
• Familiarity with organoids, primary tissues, or organ-on-chip systems.

Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.

Company:

Nurix Therapeutics is a biopharmaceutical company focused on the discovery, development and commercialization of small molecule therapies designed to modulate cellular protein levels as a novel treatment approach for cancer and immune disorders. Leveraging Nurix’s extensive expertise in E3 ligases together with its proprietary DNA-encoded libraries, Nurix has built DELigase, an integrated discovery platform to identify and advance novel drug candidates targeting E3 ligases, a broad class of enzymes that can modulate proteins within the cell. Nurix’s drug discovery approach is to either harness or inhibit the natural function of E3 ligases within the ubiquitin proteasome system to selectively decrease or increase cellular protein levels. 

Nurix’s wholly owned pipeline comprises targeted protein degraders of Bruton’s tyrosine kinase (BTK), a B-cell signaling protein, and an inhibitor of Casitas B-lineage lymphoma proto-oncogene-B (CBL-B), an E3 ligase that regulates T cell activation.  Nurix is also progressing multiple programs through partnership, including an IRAK4 degrader in Phase 1 in partnership with Gilead and a STAT6 degrader in IND enabling studies with Sanofi.  Multiple additional wholly owned and partnered programs are at various stages of preclinical development.

Position:

Reporting to the Director, Regulatory Affairs Project Management and Operations, the Senior Associate, Regulatory Operations provides key support to the Nurix Regulatory Affairs department. This position has responsibility for entry-level coordination, review, assembly and archival of regulatory submissions in Veeva RIMS and documents for health authorities (US FDA and global equivalents).  The Senior Associate, Regulatory Operations will provide support for multiple regulatory activities, studies, and programs. The individual will have responsibility to understand and implement regulatory guidance and help ensure regulatory compliance for assigned projects.  The Senior Associate should have 2–3 years’ experience in Regulatory Affairs or Regulatory Operations. Working knowledge of at least one functional discipline (e.g. Regulatory, Clinical, Nonclinical, Clinical Pharmacology or Chemistry Manufacturing and Controls) and a general knowledge of clinical development preferred.  The candidate should have a can-do attitude and experience working in Veeva RIMS. Also, the candidate should be eager to learn regulatory and clinical trial requirements, best practices, and provide support for Regulatory programs and leadership. 

Responsibilities:

• Under the strategic direction of the SVP of Regulatory Affairs and the Director of Regulatory Affairs PM and Operations, the candidate will support the planning, coordination, tracking and execution of submissions and responses to global regulatory authorities
• Assist Regulatory team, project teams and Clinical Research Organization (CRO) counterparts in the implementation of regulatory plans, timely delivery, and submission of regulatory documentation
• Preparation of Regulatory submission documentation (e.g Forms, Cover Letter) as requested
• Support team with formatting, QC and publishing of submission documents and packages
• Manage and support Veeva RIMS processes such as HAI, SCP and Archiving
• Manage authoring and review workflow in Veeva RIMS according to defined timelines
• Coordinate with regulatory colleagues and cross-functional departments to prepare, compile, review, and submit documents or information necessary to health authorities in accordance with regulations, guidelines or queries IN Veeva RIMS using SCP
• Maintain archival copies of health authority submissions (e.g., IND, CTA, NDA, and MAA), correspondence and a record of health authority obligations, and commitments
• Maintain current knowledge of applicable US and global regulations, guidance, and standards for drug development and product registration. Participate in Regulatory Intelligence activities to help inform team members of new applicable guidelines and conduct training sessions on new guidelines/regulations if necessary
• Participate in kick-off and project-based meetings related to regulatory submissions, strategy, and comment resolution. Be a reliable resource for information following such meetings
• Follow general instructions from Regulatory management or company leadership for assigned projects while independently planning daily work tasks to complete projects on time. Seek guidance on project/task priorities as needed
• Communicate important project decisions or challenges to Regulatory leadership
• Create or contribute to Standard Operating Procedures (SOP), checklists and training Materials for Regulatory department activities
• Support contracts and Purchase order for the Regulatory Affairs department

Requirements:

• Bachelor's Degree in Life Sciences or relevant field
• Minimum of 4-5 years’ experience working in Regulatory Affairs or Regulatory Operations Additional experience in the biotechnology or pharmaceutical industry preferred
• Understanding of the drug development process
• Proficient knowledge of Veeva RIMS SCP, workflows, archival, reporting…
• Experienced publisher (DocuBridge, GlobalSubmit, VeevaVault Submission…)
• Experience successfully supporting critical deliverables while maintaining agreed timelines
• Demonstrated ability to work effectively with cross-functional teams or collaborative environments.
• Basic knowledge of 21 CFR and FDA, ICH, GCP, GMP, eCTD, and global guidelines.
• Previous experience with building electronic submissions in compliance with Health Authority requirements is a plus.
• Previous experience with maintaining in-house repository for archiving regulatory submissions and Health Authority correspondence in 21 CFR Part 11 compliant system (e.g., Veeva) is a plus.
• Able to take ownership of a given assignment, proactively consulting other project team members and other department representatives for information or guidance, as necessary.
• Superior communication skills: oral, written, with proven negotiation skills, and strong time-management.
• Excellent Computer Skills MS Word, Excel, Power Point, Smartsheet and document management software/system, templates.
• Ability to work on multiple tasks and prioritize tasks to meet company objectives. Strong attention to detail and time management skills are essential.

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view.

Salary Range:   140K - 160K  plus bonus & equity.

Location:  Brisbane, CA (Onsite role)

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/). 

Nurix Therapeutics is a clinical stage biopharmaceutical company focused on the discovery, development, and commercialization of targeted protein degradation medicines, the next frontier in innovative drug design aimed at improving treatment options for patients with cancer and inflammatory diseases. Powered by a fully AI-integrated discovery engine capable of tackling any protein class, and coupled with unparalleled ligase expertise, Nurix’s dedicated team has built a formidable advantage in translating the science of targeted protein degradation into clinical advancements. Nurix aims to establish degrader-based treatments at the forefront of patient care, writing medicine’s next chapter with a new script to outmatch disease.

Position Summary

This role owns IT service delivery and vendor operations at Nurix. You will manage our internal service delivery team, oversee our managed service providers, and lead initiatives to improve how IT supports the business. Beyond running day-to-day operations, you will design and evolve Nurix's IT operating model as the company grows.

The goal is not simply to manage vendors, It’s to create a service experience where employees get reliable help, problems get solved quickly, and IT enables rather than slows down the work.  You're empowered to restructure vendor relationships, change providers, or build internal capability as needed to achieve that outcome.

This is a growth role. In Year 1, the focus is building a strong operational foundation. As that foundation matures, the role expands toward direct engagement with lines of business as an IT strategic partner.

Responsibilities

Service Delivery

• Lead the service delivery function, including the Service Delivery Manager and coordination with MSPs
• Own escalations and ensure employees receive timely, quality support
• Design and improve service delivery processes: documentation, knowledge
  management, meaningful metrics
• Evolve the operating model over time—assess what should be handled internally vs. through partners
• Manage on-prem infrastructure through MSPs; build internal capability if and when it makes sense

Vendor Operations

• Own vendor relationships across the IT service provider portfolio
• Set clear expectations: scope, performance standards, accountability
• Lead contract negotiations and renewals to improve value
• Ensure vendors build our capability—we want to learn, not become dependent
• Rationalize the vendor portfolio as needed to improve outcomes

Planning & Programs

• Develop a technology roadmap aligned with Nurix's clinical and business milestones, including sequencing and tradeoff rationale to support leadership decision-making
• Help leadership prioritize initiatives—frame options, clarify tradeoffs, recommend paths forward
• Lead cross-functional projects spanning infrastructure, security, and applications
• Support budget development, expense tracking, and financial reporting

Collaboration

• Coordinate with Information Security on system hardening and compliance
• Work with Cloud Infrastructure on AWS and cloud-first initiatives

Qualifications

• 10+ years in IT, including 5+ years in leadership or management roles
• Experience managing vendor relationships: contracts, performance, accountability
• Background in biotech, pharma, or life sciences
• Track record building roadmaps and driving cross-functional alignment
• Strong at translating business needs into actionable plans
• Effective communicator across technical and scientific audiences
• Bachelor's degree in a technical field, or equivalent experience

Preferred

• Familiarity with GxP and regulated IT environments
• Experience with research platforms (ELN, LIMS, scientific data systems)
• AWS or cloud platform experience
• Product management or digital strategy background
• Coordinate with Information Security on system hardening and compliance
• Work with Cloud Infrastructure on AWS and cloud-first initiatives

Fit with Nurix Culture and Values

• Strong team orientation; highly collaborative
• Ability to function in a dynamic environment
• Solutions and results-oriented focus
• Hands-on approach; resourceful and open to diverse points of view

Salary Range: $ 214,637 – $244,431

Location: Brisbane, CA - Onsite 

Nurix Therapeutics, Inc. is committed to protecting and respecting your privacy and personal information, including information collected by Nurix when you apply for a job with Nurix or in the course of your employment with Nurix.  By applying for a position at Nurix, you agree to our collection and use of personal information as described in our Privacy Policy (https://www.nurixtx.com/privacy-policy/). 

About this opportunity:

At Freenome, we are seeking a Research Associate II to help grow the Process Development team within Genomics Early Development. The ideal candidate will work to optimize next-generation sequencing (NGS) processes and develop new methodologies on our multiomics platform. This person will work cross-functionally with Research & Development, Automation, Computation Science, Quality, Regulatory, Laboratory Operations, and Program Management on the development, characterization, scale-up and transfer of complex methodologies, processes and assays to Operations. You are passionate about contributing to developing life-saving diagnostics through early cancer detection, and you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.

The role reports to the Senior Manager of Genomics Early Development. This role will be an onsite role based in our Brisbane, California headquarters.

What you’ll do:

• Apply hands-on knowledge of molecular biology, nucleic-acid biochemistry and next generation sequencing to develop and optimize NGS based methods and processes.
• Execute experiments to characterize and optimize NGS workflows, converting prototypes into high-throughput automated assays.
• Participate in data analysis and visualizations to answer experimental questions and identify areas for workflow optimization.
• Present findings at team meetings and prepare technical reports for internal and external stakeholders.
• Collaborate with cross-functional teams to integrate process improvements into the overall diagnostic workflow.
• Assist with generating Standard Operating Procedures and Work Instructions with Laboratory Operations and Clinical Laboratory for transfer.
• Support troubleshooting workflow issues, perform root-cause determinant experiments and propose effective data-driven solutions.
• Maintain detailed records of experiments, data, results and methodologies in compliance with Good Laboratory and Documentation Practices (cGLP, cGDP).

Must haves:

• Bachelor’s or Master’s in Molecular Biology, Genetics, Biochemistry, or a related field with 2+ years of relevant industry experience.
• Hands-on experience in NGS based techniques, including nucleic acid extraction, library preparation, and sequencing.
• Experience with handling plasma and cfDNA in NGS workflows with low-volume, plate-based assay formats.
• Effectively communicates with team and cross-functional partners.
• High attention to detail - record and document accurate, objective observations, assess impact, and perform troubleshooting as needed.
• Excellent problem-solving skills, proactively looks for potential roadblocks, characterizes root causes to problems and collaborates with appropriate stakeholders.
• Ability to work independently as well as part of a cross-functional team.
• Flexible and adaptable to change and embrace a fluid work environment.

Nice to haves:

• Familiarity in a common scientific programming language (e.g., Python, R) is desirable.

Benefits and additional information:

The US target range of our hourly rate for new hires is $31.67 - $49.52. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered.  Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information.  

Freenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.

Applicants have rights under Federal Employment Laws.  

• Family & Medical Leave Act (FMLA)
• Equal Employment Opportunity (EEO)
• Employee Polygraph Protection Act (EPPA)

#LI-ONSITE

Role

The Director, Business Development is a senior individual contributor responsible for sourcing, advancing, and closing strategic partnerships pharmaceutical companies. This role carries a significant individual bookings target and is accountable for building and converting a high-quality pipeline aligned with Vivodyne’s commercial priorities.

The Director, BD  will operate with a high degree of autonomy and strategic judgment; owning account strategy, shaping deal structures, and leading cross-functional execution across Science, Bio, Legal, and Finance. Success in this role requires balancing hands-on deal execution with thoughtful account planning and market insight.

Responsibilities

Ownership & Deal Execution

• Carry and deliver against an individual quarterly and annual bookings target.

• Source, qualify, and advance new partnership opportunities with mid-sized and large pharma companies and AI/data-centric partners.

• Lead opportunities through the full deal lifecycle: discovery → scoping → proposal → negotiation → close.

• Shape opportunity-specific deal structures including pilot studies, discovery programs, efficacy/tox engagements, and data-enabled collaborations.

• Own follow-through and momentum on active deals to ensure timely progression and closure.

• Run weekly pipeline reviews to reduce slippage, re-qualify deals, and improve forecast accuracy.
  
  

Account Strategy & Pipeline Management

• Develop and execute account-level strategies for a defined set of target and active accounts.

• Build and maintain a robust personal pipeline aligned with revenue goals and priority therapeutic areas.

• Conduct stakeholder mapping to identify scientific, operational, and commercial decision-makers and influencers.

• Expand existing accounts by identifying adjacent research groups, new use cases, or follow-on program opportunities.

• Maintain accurate CRM hygiene, deal staging, and pipeline updates.
  
  

Strategic Contribution 

• Translate Vivodyne’s platform capabilities into tailored value propositions aligned to customer discovery-stage needs.

• Provide structured market and customer feedback to inform leadership, product positioning, and messaging.

• Contribute to the evolution of deal archetypes, pricing approaches, and engagement models based on learnings.

• Collaborate with Marketing and Bio teams to refine scientific narratives and customer-facing materials.

• Deliver structured market and customer intelligence to leadership to refine positioning, pricing/deal archetypes, and therapeutic-area prioritization.

Cross-Functional Deal Leadership

• Quarterback cross-functional deal teams, coordinating inputs from Science, Bio, Legal, and Finance.

• Ensure technical feasibility and resourcing alignment before advancing proposals.

• Partner with Legal and Finance during contracting and commercial negotiations.

• Communicate deal status, risks, and forecast updates clearly to BD and company leadership.

• Lead contracting and commercial negotiations to close efficiently (anticipate pharma procurement/legal patterns, manage redlines/risks, drive velocity through clear negotiation strategy).
  
  

Event  Engagement

• Represent Vivodyne at key industry conferences and scientific meetings.

• Execute targeted meeting strategies and follow-up plans to support personal pipeline goals.

• Participate in seminars, site visits, and customer-facing scientific discussions as needed.

• Capture and operationalize field intel from conferences (themes, objections, competitor claims) into messaging updates and enablement for the broader BD/GTM team.

• Execute rigorous post-event follow-up with clear conversion targets to advance opportunities toward close.

Requirements

Required

• 7–10+ years of business development or alliance experience in biotech or pharma.

• Proven success carrying an individual quota and closing complex, multi-stakeholder deals.

• Experience supporting or working within discovery platforms, preclinical services, or advanced research.

• Strong understanding of drug discovery workflows and customer decision dynamics.

• Ability to translate complex science into clear, customer-aligned value propositions.

• Highly organized, with experience managing end to end sales cycles and a sizable personal pipeline.
  
  

Preferred

• Familiarity with oncology discovery, RNA modalities, and/or preclinical toxicology.

• Exposure to AI/ML-enabled discovery or data-driven collaboration models.

• Experience working with novel or emerging platform technologies.
  

Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.

Role

As a Principal Mechanical Engineer at Vivodyne, you will be part of a multi-disciplinary team pushing the boundaries of automated, large-scale "organ-on-a-chip" robotics and related manufacturing systems. Your focus will be on developing and optimizing hardware and software that orchestrates robotic arms, embedded controllers, and microfluidic systems to enable high-throughput, high-precision biological workflows.

This role requires expertise across hardware and software, but primarily hardware.  From high-level motion control and machine vision to robotics programming and embedded firmware. You’ll work extensively with existing Python (less so with, C#, and C++) codebases, ensuring seamless system integration and performance.

You are a mechanical design expert.  Things like kinematic docking, 440 vs 316, FEA, and error budgets are very familiar to you.  Your friends include McMaster-Carr, Misumi, and Grainger. 

Collaboration is key—you’ll engage with mechanical engineers, biologists, immunologists, AI scientists, and process engineers to design and refine automation workflows that drive breakthroughs. We’re looking for a problem solver comfortable working across multiple domains, thriving in a fast-paced, high-innovation environment that values continuous learning and technical excellence.

This is a full-time, onsite role in San Francisco, where you’ll be designing, building, and testing some of the most advanced automation and high-throughput biology systems in the world.

Responsibilities

• Architect, design, and implement advanced automation systems, ranging from automated microfluidic manufacturing to high-precision mammalian cell culture platforms—all of which are mission-critical and highly visible both internally and externally.
• Develop hardware and software systems that acquire and process data reliably, ensuring smooth handoffs to production through rigorous documentation, data acquisition, and analysis.
• Embrace the dynamic nature of a rapidly growing startup, working across multiple projects and disciplines.
• Collaborate cross-functionally with Product leads, tissue engineers, microfluidics specialists, and AI researchers etc. to gather requirements, set technical objectives, and integrate new features into our robotics platforms.
• Design and implement resilience mechanisms to ensure system robustness, enabling fault detection, fault recovery, and minimal downtime, while maintaining data integrity.
• Proactively identify optimization opportunities, selecting priorities through engineering analysis and data-driven decision-making.
• Communicate progress and findings to internal stakeholders—including mechanical engineers, data scientists, and senior leadership—through data-laden presentations and technical reports.

Requirements and Expectations

Technical Expertise & Knowledge

• Bachelor’s degree (M.S. or Ph.D. preferred) in Mechanical Engineering, Chemical Engineering, or a related field with a focus on microfluidics, tissue engineering, or lab automation at least six years of directly relevant industry experience.
• Broad experience in hardware and, preferable, software design for automation, spanning off-the-shelf solutions and custom-built systems—you have developed complex automation workflows for production-level environments.
• Proficiency in key hardware and software tools, including SolidWorks (expert-level, CAM experience is a plus), and at some exposure to Python/Matlab/C++/C#/Javascript/etc.
• Hands-on experience with commonly used automation hardware, such as vision/camera systems (optics and/or optomechanical expertise is a plus), motion control, liquid handling, and pick-and-place robotics.
• Highly knowledgeable in various Manufacturing Technologies, you know how things are made and which approaches fit a particular application
• Industry-specific expertise is highly valued:
• Biotech/lab automation or semiconductor robotics experience is a strong advantage.
• Knowledge of microfluidics and fluid handling systems.
• Experience integrating robotics with high-content imaging and confocal microscopy systems, optimizing workflows for advanced imaging pipelines.
• Biology background or familiarity with cell and tissue engineering concepts is a significant plus, especially in handling biological samples.
• Bonus points for experience with:
• Electronics/PCBA design or basic knowledge (reading schematic, troubleshooting interconnects), statistical analysis/data collection to inform design performance rigorously

Problem Solving & Ownership

• You take an outcome-driven approach, translating project goals and technical challenges into systematic, resilient robotics solutions.
• Strong ownership mentality, ensuring the timely delivery of high-reliability features and improvements.
• Growth-oriented, continuously seeking ways to enhance automation processes, optimize robotic operations, and drive innovation.

Collaboration & Communication

• A team player, capable of working with engineers, scientists, and external stakeholders to define requirements, refine designs, and communicate project progress effectively.
• Clear communicator, able to explain complex robotics concepts to cross-functional teams, from software engineers to biologists.
• Interdisciplinary mindset, integrating feedback from various fields to develop thoughtful, iterative design improvements.

Innovation & Leadership Mindset

• Passionate about staying at the cutting edge of robotics, bringing fresh ideas from emerging technologies, best practices, and research to the team.
• Comfortable taking initiative in uncharted territories, whether it’s developing new motion-planning algorithms or integrating novel sensors and hardware.

Why Vivodyne?

• High-Impact Mission – Play a pivotal role in transforming drug discovery and human therapeutics through advanced robotics and automation.
• Multi-Disciplinary Exposure – Work alongside leading experts in robotics, AI, biology, and microfluidics, expanding your expertise in a truly collaborative setting.
• Growth Opportunities – A fast-growing startup environment with significant autonomy, ownership, and influence over best practices in the intersection of biotech and robotics.
• Innovative Culture – Join a team that prioritizes continuous learning, rigorous engineering and scientific standards, and bold problem-solving.

If you're excited about revolutionizing automation in organoid engineering and biotech—while pushing the boundaries of robotics, AI, and advanced systems—let’s connect! Please submit your resume and a brief statement of interest. We look forward to exploring the opportunity together.

Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.

Role

The AI Team at Vivodyne tackles some of the hardest and most interesting challenges in science and engineering. With access to extraordinarily feature-rich and massive-scale Vivodyne human tissue imagery, we are advancing the frontiers of artificial intelligence and its applications in biology. We are building a portfolio of AI technologies to automate the discovery, development, and de-risking of novel therapies using our unique technology platform, including single-cell 3D phenomics/machine vision, multimodal (multi-omic) translation, and reinforcement learning for robotic planning & study design, among others.

As an AI Senior Scientist, you will leverage your deep expertise in developing large-scale models (including Transformer, Diffusion, and hybrid architectures) and Generative AI solutions to help turn our state-of-the-art imaging and multi-omics datasets into groundbreaking scientific insights. You will collaborate closely with biologists, engineers, and AI specialists to deliver robust, production-ready algorithms and models that power Vivodyne’s high-impact discoveries.

This role will be based on-site at our offices in Brisbane, California

Responsibilities

• Scientific Innovation — Work closely with internal and external stakeholders to understand their scientific objectives and innovate new approaches that utilize Vivodyne’s massive-scale imaging and multi-omics datasets.

• Model Development — Lead hands-on development of cutting-edge machine learning models (Transformers, Diffusion, hybrid architectures, etc.) with a focus on image processing, image enhancement, and Phenomap embeddings.

• Data Pipeline Optimization — Build and deploy pipelines capable of scaling to petabyte-scale data, ensuring robust MLOps practices on AWS or equivalent cloud platforms.

• Multimodal Integration — Explore and develop novel methods to incorporate multi-omics data into imaging-based Phenomaps, advancing the state of the art in multimodal phenotypic analysis.

• Collaboration & Communication — Partner with tissue engineers, microfluidics experts, and robotics engineers to refine data collection strategies, provide feedback on imaging system performance, and identify opportunities for improved AI-driven solutions.

• Scientific Rigor & Leadership — Uphold scientific excellence through peer reviews, proper documentation, and clear communication. Drive a culture of continuous improvement, best practices, and adherence to rigorous research methodologies.

• Scalability & Efficiency — Emphasize modularity, composability, and performance efficiency in designing and implementing high-throughput compute and analytics pipelines.

• Domain & Technical Growth — Remain current with the latest research trends in Generative AI, biomedical imaging, cloud computing, and data-intensive training. Proactively share knowledge and mentor teammates to foster overall organizational expertise.

Requirements and Expectations

• Scientific Excellence — Stay current with AI/ML research, especially in Generative AI, Transformers, Diffusion models, and multi-modal architectures. Apply rigorous, data-driven methods for sound outcomes.
• Hands-On Leadership — Set high standards for model development and code quality, mentoring team members and fostering innovation.
• Accountability — Own model and infrastructure development from concept to deployment, delivering reliable, scalable solutions aligned with Vivodyne’s mission.
• Problem Solving & Adaptability — Develop creative solutions to novel research challenges, thriving in a fast-paced, dynamic startup environment.
• Collaboration & Communication — Work cross-functionally to align AI strategies with business goals, ensuring clear communication and consensus-building.
• Delivering Results — Prioritize impactful research, using project management best practices to track progress, mitigate risks, and meet deadlines.
• Architecture & Coding — Design scalable, cost-effective systems and produce clean, well-documented code with continuous testing and governance compliance.
• Resource Optimization — Apply financial discipline to maximize the efficiency of compute, storage, and third-party services.
• Team & Thought Leadership — Foster an inclusive environment, mentoring future leaders and representing Vivodyne in AI research and industry discussions.

Qualifications

• Education & Experience

• PhD in Computer Science, Applied Mathematics, or a related field, or equivalent practical experience.
• Proven expertise developing and deploying advanced ML architectures (Transformers, Diffusion, multi-modal models) in Generative AI settings.
• Demonstrated history of success with image processing and large-scale model training.

• Technical Skills

• Strong knowledge of AWS or another major cloud provider for MLOps, big data processing, and scalable computing.
• Experience building models for petabyte-scale datasets and understanding the associated architectural and operational complexities.

• Domain Expertise (Preferred)

• Familiarity with biological or biomedical imaging; advanced knowledge in multi-modal Phenomaps, especially integrating imagery with multi-omics data, is a major plus.

• Additional Desired Skills

• Prior experience with HPC, GPU clusters, or distributed computing frameworks.
• Comfortable with container orchestration and open-source data engineering/ML frameworks.

• Soft Skills & Leadership

• Strong written and oral communication skills, with a proven ability to present complex technical topics to non-experts.
• Demonstrated ability to thrive in ambiguous environments, driving clarity and direction with minimal supervision.

Vivodyne, Inc. is an equal opportunity employer. Vivodyne complies with all laws respecting equal employment opportunity and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law.