Jobs Companies Quantum-Si Senior Software Engineer, Instrument Control

About this Senior Software Engineer, Instrument Control role at Quantum-Si

Quantum-Si · Onsite · San Diego, CA

We are looking for an experienced and ambitious instrument control software engineer to join our instrument software team. We are developing advanced life science research instruments that combine precision hardware control, imaging, and automation. Our software is at the intersection of control systems, hardware communication interfaces, distributed services, and Linux applications. This complex system requires experienced software engineers to maintain and improve existing code, as well as enable us to continue scaling the capabilities and throughput of our instrument platform as we develop future generations of instruments. 

This is an opportunity to work across the full technology stack—from low-level hardware integration and instrument automation to distributed services and user-facing applications—while helping shape the architecture of next-generation scientific instruments. 

As part of our team, your core responsibilities will be:  

  • Design, develop, and maintain software for the instrument, ensuring high performance and reliability. 
  • Develop and integrate data acquisition, motion control, signal processing, data analysis, automated workflows, and user interfaces for a complex scientific instrument. 
  • Collaborate with systems integration and engineering teams to define and implement new instrument functionality. 
  • Refactor and improve existing software architecture to enhance maintainability and reduce technical debt. 
  • Document software designs, code, and processes to ensure clarity and maintainability. 
  • Troubleshoot and debug software issues, providing timely resolutions. 

 

Qualifications 

Baseline skills/experiences/attributes: 

  • Bachelor’s degree in Computer Science, Electrical Engineering or related discipline (or equivalent practical experience) 
  • 5+ years of professional experience in software development, with a strong focus on C# 
  • Experience with .NET 6+ for developing and maintaining cross-platform applications 
  • Familiarity with Linux operating systems (Ubuntu preferred) 
  • Proficiency with Git and collaborative development workflows, including code review and Agile/Scrum practices 
  • Experience with automated testing (unit and integration) and CI/CD pipelines 
  • Experience with multi-threaded programming and real-time data acquisition 
  • Experience with RPC frameworks (e.g., gRPC) for inter-process and inter-service communication 
  • Proven track record in software architecture improvement, refactoring, and managing technical debt 
  • Strong documentation skills to ensure maintainability and clarity of the codebase 
  • Experience debugging, profiling, and optimizing software for performance, memory usage, and real-time constraints 

Ideally, you also have these skills/experiences/attributes (but it’s ok if you don’t!): 

  • Interfacing with communication protocols (Serial, USB, I2C, CAN) 
  • Knowledge of control systems, including PID control loops, motion control, and trajectory planning 
  • Proficiency in developing GUIs using Avalonia 
  • Experience with Python scripting for automation and control logic 
  • Experience with Linux system-level scripting and configuration (e.g., bash, systemd, udev) 

 

The estimated base salary range for this position in the United States is $155,000 - $175,000. In addition to base salary, full-time employees are eligible to participate in Quantum-Si's discretionary annual bonus program and may receive equity awards as part of the total compensation package. Actual compensation will be determined based on a variety of factors, including, but not limited to, the position level, relevant skills, knowledge, experience, qualifications, geographic location, internal equity, and market data.

Quantum-Si also offers a competitive benefits package designed to support employees' health, well-being, work-life balance, and family needs. Benefits include:

· Comprehensive medical, dental, and vision insurance coverage

· Health Savings Account (HSA) and Flexible Spending Account (FSA) options, where applicable

· Company-paid life and accidental death & dismemberment (AD&D) insurance

· Short-term and long-term disability coverage

· Employee Assistance Program (EAP) resources to support personal and professional well-being

· Discretionary paid time off and company-paid holidays

· Parental leave to support employees welcoming and caring for a new child

· 401(k) retirement savings plan with both pre-tax and Roth contribution options

Additional Information

Candidates must be authorized to work in the United States. Quantum-Si does not provide employment-based immigration sponsorship of any kind for this position, including support for applicants currently pursuing permanent residency (Green Card sponsorship).

 

Quantum-Si does not accept unsolicited agency resumes.

 

Quantum-Si is an E-Verify and equal opportunity employer regardless of race, color, ancestry, religion, gender, national origin, sexual orientation, age, citizenship, marital status, disability or Veteran status. All your information will be kept confidential according to EEO guidelines.

 

Ready to apply to Quantum-Si?
Apply to Quantum-Si

How this Software Engineer salary compares

This role pays $165,000/yrbelow the typical range for Software Engineer roles.

$156,600 median $187,600 $225,398

Typical range $167,500–$220,000/yr, from 29 comparable Software Engineer listings on JobsRadar (pay annualized to USD). See Software Engineer salary insights →

Similar jobs

PlayStation Global
Staff Software Engineer – Data
PlayStation Global
⚡ Apply early United States, San Mateo, CA Onsite $198,200–$297,400
● New 👁 Seen ✓ Applied 5h ago
Speechify
Software Engineer, iOS Core Product - San Diego, CA, USA
Speechify
⚡ Apply early San Diego, CA, USA Onsite
● New 👁 Seen ✓ Applied 13h ago
Speechify
Senior Software Engineer, Core Experiences - San Diego, CA, USA
Speechify
⚡ Apply early San Diego, CA, USA Onsite
● New 👁 Seen ✓ Applied 13h ago
Speechify
Software Engineer, Data Infrastructure & Acquisition - San Diego, CA, USA
Speechify
⚡ Apply early San Diego, CA, USA Onsite $140,000–$200,000
● New 👁 Seen ✓ Applied 14h ago
PlayStation Global
Copy of Software Engineer II, Data Platform
PlayStation Global
⚡ Apply early United States, San Mateo, CA Onsite $150,100–$225,100
● New 👁 Seen ✓ Applied 1d ago
PlayStation Global
Senior Software Engineer (Frontend), Social
PlayStation Global
⚡ Apply early United States, Los Angeles, CA Onsite $177,300–$265,900
● New 👁 Seen ✓ Applied 2d ago
STR
Associate Software Engineer
STR
⚡ Apply early San Diego, CA Hybrid $110,000–$120,000
● New 👁 Seen ✓ Applied 2d ago
Reliable Robotics Corporation
Displays Software Engineer, C/C++
Reliable Robotics Corporation
⚡ Apply early Mountain View, CA Onsite $185,000–$245,000
● New 👁 Seen ✓ Applied 5d ago
VT
Software Engineer
Voyager Technologies, Inc.
⚡ Apply early San Diego, CA Onsite $140,000–$175,000
● New 👁 Seen ✓ Applied 6d ago

Sign up for suggestions tailored to the jobs you open and the searches you save.

More jobs at Quantum-Si

See all jobs at Quantum-Si →

Apply now
🤖

Whoa — hold up

JobsRadar was built for real people having a rough time in their job search — not for automated requests. You're clicking way too fast and you're now temporarily blocked.

Come back later. If you're genuinely job hunting, we've got your back — just act like a human.

Catch your next role the second it’s posted.

Create a free account and we’ll watch the boards for you — the instant a job matches your search, it lands in your inbox or Telegram. No digging, no refreshing.

Create free account

Free forever · takes 30 seconds · already have one?

Get an edge on your job hunt.

Join our Telegram channel for the stuff that helps you land the role — salary benchmarks, the weekly market pulse, and new-feature drops. No spam, just signal.

Join the channel — it's free