Über diese Associate Scientist – Flow Cytometry (Contract) Stelle bei Slingshot Biosciences
Slingshot Biosciences is a fast-growing life sciences company with a platform technology and paradigm-shifting mission to make precision-engineered cell mimics the gold standard for all cell-based assay controls. We are transforming cell-based applications with the most robust, scalable, and reproducible controls available, including TruCytes™ Biomarker controls, SpectraComp® compensation controls, ViaComp® cell health controls, and FlowCytes® instrument controls.
Our TruCytes cell mimics precisely replicate real cells’ optical and biochemical properties - without the sourcing, quality, or cost challenges of traditional controls. Trusted in cell-based applications across cell therapy, drug development, and diagnostics, they empower process and analytical development, quality control, potency assessments, multi-site validations, clinical research studies, and assay development and validation.
Slingshot is seeking motivated, creative team members who think outside the box. We empower employees to own their work, contribute ideas quickly, and improve processes. Come join our cross-disciplinary and world-class team that is delivering game-changing solutions for cell-based applications!
Slingshot Biosciences is seeking a Flow Cytometry specialist to help us build our next portfolio of products. You will be a key part of the product development process, providing expertise to R&D and Manufacturing. You will also generate publication-quality results for competitive marketing purposes and general publication/release, as well as examining root cause issues related to product complaints.
To be successful in this role, you'll need extensive knowledge of flow cytometry (antibody panel design and data analysis using relevant software) using a variety of instruments, biochemistry, and molecular biology. Proactive communication, diligent execution and documentation of complex workflows, and a highly collaborative mindset will be critical to success. We also place a premium on creativity, intellectual curiosity, flexibility, resiliency, drive, and a proactive, can-do attitude.
This is a full-time, on-site, 3-month contract position at Slingshot's headquarters in Emeryville, CA, reporting to the technical lead of our Flow Cytometry function. For the successful candidate, this will be a fantastic opportunity in a dynamic, fast-paced environment and a chance to deliver products that will positively impact human health.
Key Responsibilities
- Test and validate new product designs on a range of flow cytometry platforms
- Document, implement and transfer best practices and protocols for sample preparation, staining, and data acquisition to ensure accurate and reproducible results
- QC products using flow cytometry, analyze flow cytometry data using software in the functional area such as FloJo, and extract meaningful data while ensuring data integrity and accuracy
- Conduct regular maintenance and calibration of flow cytometry instruments to ensure optimal performance and data accuracy
- Troubleshoot and resolve technical issues with flow cytometers and associated equipment
- Ensure that product vision is maintained and realized through execution and documentation of design control processes, including verification & validation, stability studies, and design reviews
- Generate competitive marketing material for new product introductions, product comparisons, and conferences, e.g. presentations and posters as needed
- Investigate product complaint issues and perform root cause analysis independently or in conjunction with the QA team as needed
- Exhibit active intellectual involvement in research projects including experimental design, execution, and reporting in support of our scientists and senior scientific leadership
- Write technical reports of the test results with statistically derived conclusions
- Develop SOPs to transition research into production and manufacturing
- Provide feedback about new product concepts and needs in RUO and IVD arenas
- Ensure compliance with laboratory health and safety guidelines; familiarity with ISO 9001 and GMP guidelines is desired
- Other duties as assigned
Qualifications
- Extensive background in flow cytometry across multiple different instrument platforms, particularly spectral flow cytometry
- Advanced expertise in multiparameter (>10-color) flow cytometry analysis, compensation and gating strategies for analysis of mixed cell populations
- Experience analyzing flow cytometry data in software such as FloJo
- Strong understanding of stability principles, including shelf life determination and accelerated stability testing
- Good knowledge of laboratory health and safety standards, including working with blood products such as Leukopaks
- Excellent analytical and research skills
- Attention to detail and excellent communication skills/systems in record keeping/documentation
- Flexibility to work after hours or over weekends if needed
- Strong problem-solving skills with the ability to drive work independently
- PhD in Cell Biology/Biochemistry/Biology or equivalent, Masters with 3+ years experience, or Bachelors with 6+ years experience
About Slingshot:
Our north star is to make healthcare more accessible around the world. We are doing this by advancing cell biology to develop innovative solutions for human health.
At Slingshot, we value diversity and believe that a variety of backgrounds and experiences leads to more innovative ideas and a better understanding of our customers. Passion is at the core of our values, and employees are encouraged to pursue their passions in their work and contribute to the company's overall mission.
Slingshot Biosciences is an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, genetic information, protected veteran status, or any other characteristic protected by law.
Legal authorization to work is required for all roles. Employment eligibility will be verified in accordance with applicable laws in the country where the position is based. For U.S.-based roles, this includes completion of required employment eligibility verification. For international roles, employment may be facilitated through an Employer of Record (EOR) in compliance with local regulations.
Slingshot Biosciences is a fast growing life sciences company with a platform technology and paradigm-shifting mission to make synthetic cells the gold standard for all cell-based applications. We’re a team of individuals from diverse backgrounds who are united by the common goal of making diagnostics and therapeutics more accessible. Our mission is to improve access to advanced medical innovations and healthcare using our synthetic cell platform. We seek to create an environment where we inspire excellence, and cultivate a growth mindset, and are always looking for people to join our team of creative problem solvers!
