Welcome to Praxis' Careers Portal
You can search for opportunities below. If you do not see an open position that matches your qualifications at this time please submit your interest to the "General Application" job listed below. We look forward to hearing from you!
Please note: We are aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any positions. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Pick a job to read the details
Tap any role on the left — its description and apply link will open here.
Share this job
Location: This position is field based and requires 60-80% travel.
The Opportunity
Praxis is seeking a field-based Clinical Trial Liaison (CTL) to partner directly with clinical trial sites and drive high-quality, high-urgency study execution. This is a hands-on, field-facing role focused on building trusted relationships with investigators and site staff, delivering scientific and protocol expertise, and addressing the real-world challenges that impact trial performance.
You will play a critical role across the lifecycle of study execution, from site initiation and training through enrollment and retention, while proactively identifying risks and working cross-functionally to resolve them. This is not a passive support role; you are expected to take ownership of site performance, think critically, and act with urgency to drive results.
We are open to hiring across levels and seek individuals who can operate with a high degree of ownership in the field, whether growing into the role or already leading independently. Leveling will reflect experience, judgment, and demonstrated ability to influence trial outcomes.
Success in this role requires strong clinical credibility, clear and effective communication, and the ability to operate autonomously in a high-travel, fast-paced environment.
Primary Responsibilities
Qualifications and Key Success Factors
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!
To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. This range reflects the base salary the Company reasonably expects to pay for the position at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Ready to apply?
Apply to Praxis Precision Medicines, Inc.Share this job
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
Praxis is seeking an Senior Medical Science Liaison (Sr. MSL) to lead and develop a team of Medical Science Liaisons (MSLs) supporting pre-launch and launch activities for ulixacaltimide in movement disorders. This is a hands-on leadership role responsible for building, coaching, and directing a high-performing field medical team, while also maintaining strategic engagement with key investigators, movement disorder specialists, and other neurology stakeholders.
This individual will play a critical role in translating medical strategy into field execution, ensuring high-quality scientific exchange, and driving clinical and account readiness in advance of and following potential approval. The role requires a balance of people leadership, strategic thinking, and field engagement, operating as both a coach and scientific leader within a dynamic, fast-paced launch environment.
Given the significant unmet need in essential tremor and the opportunity to introduce a novel therapeutic option, this role will help shape disease education, stakeholder engagement, and the evolving treatment paradigm across both academic and community neurology settings.
The Associate Director/Director will partner cross-functionally with Medical, Clinical Development, Commercial, and Market Access teams to align on strategy, shape field insights, and ensure consistent, compliant execution across the MSL organization.
This role will also be responsible for translating field insights into actionable strategic recommendations, representing the voice of the external medical community, and shaping field medical strategy across the product lifecycle from pre-launch through post-launch adoption.
The role includes responsibility for field team effectiveness, including performance management, territory alignment, and resource deployment to ensure optimal execution and impact.
This role will report directly to the Head of Field Medical Affairs and serve as a key leader within the field medical organization.
Success in this role requires strong clinical credibility, excellent communication skills, strategic thinking, and comfort operating autonomously in a fast-paced environment.
Primary Responsibilities
Team Leadership & Development
Field Strategy & Execution
KOL Engagement & Scientific Leadership
Insight Generation & Cross-Functional Collaboration
Operational Excellence
Qualifications and Key Success Factors
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!
To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. This range reflects the base salary the Company reasonably expects to pay for the position at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Ready to apply?
Apply to Praxis Precision Medicines, Inc.Share this job
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
Praxis is seeking a field-based Medical Science Liaison (MSL) to support Medical Affairs activities for ulixacaltimide during prelaunch and potential launch. This role is focused on building trusted scientific partnerships, delivering high-quality scientific exchange, and generating actionable insights to inform medical strategy and ensure clinical readiness.
This is a field-facing, development-oriented role where you will engage healthcare professionals and investigators to communicate emerging clinical data, deepen disease state understanding, and identify unmet needs and potential barriers to patient care. You will work closely with cross-functional partners to ensure aligned and compliant execution of prelaunch and launch activities.
Success in this role requires strong scientific curiosity, effective communication skills, and the ability to operate with guidance while building confidence and independence in the field in a fast-paced environment.
Primary Responsibilities
Qualifications and Key Success Factors
The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!
To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below.
These ranges reflect the base salary ranges the Company reasonably expects to pay for each level at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles.
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Ready to apply?
Apply to Praxis Precision Medicines, Inc.Share this job
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
The Opportunity
Praxis is hiring a dedicated and experienced leader to serve as Head of Global Medical Affairs. You'll be responsible for building and leading the team with the goal of enhancing the development and commercialization of our neuroscience pipeline. As a key contributor you will work closely with a cross-functional group that includes counterparts in Research & Development and Commercial to implement and ensure an all-encompassing strategy. This is an outstanding opportunity to serve as a driving force in building medical affairs excellence at Praxis. The role will actively participate in strategic planning, ongoing and new development projects, existing and future corporate alliances, and partnering discussions. It is an ideal opportunity for a hands-on builder who brings both scientific rigor and strategic judgment—someone energized by creating Medical Affairs excellence from the ground up and translating complex science into real impact for patients.
Primary Responsibilities
Qualifications and Key Success Factors
Compensation & Benefits
At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive. This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future? We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP. We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns. Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring. We aim high, collaborate hard, and produce results. Let’s achieve the impossible together!
To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience.
Company Overview
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.
Diversity, Equity & Inclusion
Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.
Attention: Job Scam Alert
Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.
Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.
Ready to apply?
Apply to Praxis Precision Medicines, Inc.Cookies & analytics
This site uses cookies from third-party services to deliver its features and to analyze traffic.