Role Summary:

The Senior Director of Managed Access Programs (MAPs) leads the strategic direction and operational execution of managed access initiatives across the organization. This role is crucial in designing, implementing, and managing global programs that ensure patient access to our innovative therapeutics. This role develops policies and procedures that support equitable access while adhering to regulatory standards. This position collaborates closely with internal teams, including market access, HEOR, medical affairs, commercial, clinical, regulatory, supply chain, legal, and compliance to align MAP initiatives with the overall goals of the organization.

In addition, the person in this role partners with cross-functional teams to build and maintain strong relationships with key external stakeholders, to promote understanding and support for managed access programs. With a focus on data-driven decision-making, this role analyzes program performance, adjusting strategies as needed to maximize impact. By providing training and support to internal teams, this role ensures effective implementation of MAPs initiatives across the organization. Ultimately, this role plays a vital part in navigating complex access environments and improving health outcomes for patients.

This role is based in Waltham, MA.

Primary Responsibilities Include:

• Provide visionary leadership in the development and execution of managed access programs, ensuring that strategies align with Dyne Therapeutics' mission and objectives
• Build and oversee infrastructure necessary to implement managed access programs
• Oversee vendor responsible for program administration
• Foster a culture of collaboration and innovation within organization, guiding teams in effectively addressing patient needs and access challenges
• Design and implement comprehensive managed access policies and procedures that promote patient access to innovative therapies, with an emphasis on maintaining compliance with evolving regulatory requirements
• Utilize best practices and learnings from the field to continuously refine and enhance program frameworks
• Lead cross-functional teams, including Clinical Development, Regulatory Affairs, and Commercial, to ensure successful integration of managed access strategies across all stages of product development and commercialization
• Act as a key liaison, facilitating clear communication and alignment on priorities and objectives
• Establish and cultivate strong relationships with a diverse range of external stakeholders, including healthcare professionals, patient advocacy organizations, and regulatory bodies as appropriate
• Represent Dyne Therapeutics at conferences, meetings, and roundtable discussions, effectively advocating for managed access initiatives and fostering stakeholder trust and support
• Partner with HEOR, Market Access, Medical Affairs, and Clinical Development to implement data collection and analytics methodologies to assess program efficacy, patient outcomes, and potential access barriers
• Generate and present comprehensive reports to senior leadership and external stakeholders, offering actionable insights and recommendations for program improvement
• Develop and deliver targeted training programs and resources for internal teams regarding managed access processes, regulatory compliance, and best practices
• Ensure team is well-equipped to effectively engage with external partners and navigate complex access scenarios
• Continuously monitor and analyze industry trends, regulatory changes, and market dynamics that impact managed access programs
• Provide strategic recommendations to adapt and evolve Dyne Therapeutics' approach to access challenges in response to the shifting landscape
• Oversee the financial aspects of managed access programs, including budget planning, forecasting, and resource allocation
• Ensure that objectives are met while maximizing the impact of programs on patient access initiatives
• Foster a culture of excellence by encouraging feedback and facilitating continuous improvement within managed access programs
• Utilize lessons learned from program implementation and stakeholder interactions to drive innovation and enhance the overall effectiveness of initiatives

Education and Skills Requirements:

• Bachelor’s degree with rare disease experience in the biotech and/or pharmaceutical industry; neuromuscular experience preferred
• 15+ years of relevant experience in Medical Affairs and experience in leading global Managed Access Programs within the pharmaceutical/biotech industry; clinical operations experience also desirable
• Proven ability to lead global Managed Access Program development and implementation
• Excellent communication and relationship-building skills with KOLs and cross-functional teams
• Experienced in AI supported way of working
• Ability to interpret and communicate complex scientific data to diverse audiences
• Must be willing to travel up to 30%, inclusive of overnight and occasional weekends, to meet with customers, internal stakeholders and attend relevant conferences
• In-depth understanding of healthcare regulations, access environments, and the pharmaceutical industry landscape
• Familiarity with rare diseases and innovative therapies is highly desirable
• Strong leadership and interpersonal skills, with the ability to influence and drive cross-functional collaboration
• Excellent analytical and problem-solving capabilities.
• Exceptional verbal and written communication skills, with the ability to convey complex information clearly to diverse audiences (written, verbal and presentation)
• Proven track record of developing and executing successful managed access strategies that improve patient access and outcomes
• Excellent team player
• Strong decision maker
• Ability to work in a matrix environment
• Ability to work independently as a hands-on manager, proactively contribute as a resource when necessary
• Flexibility to adapt and meet the changing/growing needs of our customers
• High level of integrity, compliance, ethics, and transparency
• Positive team member who embodies Dyne’s Core Values
• Excitement about Dyne’s vision and mission

#LI-Onsite

Role Summary:

The Senior Manager, Scientific and Medical Education supports Dyne’s DMD program and contributes to the execution of publication and medical education activities for programs. This individual helps ensure that clinical and non-clinical data from Dyne’s studies are communicated in an accurate, timely, compliant, and compelling manner through high-quality scientific publications, including manuscripts, abstracts, posters, and oral presentations. 
 
Additionally, this role supports the creation of internal and external medical education materials such as field medical decks, medical booth collateral, symposia, and onboarding and training resources. The Senior Manager works cross-functionally within Global Medical Affairs and more broadly across the DMD program team to support aligned planning and execution of Dyne’s scientific and medical education activities. 
 
This role is based in Waltham, MA. 
 
Primary Responsibilities Include: 

• Support the development and execution of publication and medical education plans aligned with program and corporate strategies 
• Contribute to planning Dyne’s congress strategy and presence, including medical booth assets, symposia, and scientific presentations 
• Execute global medical communications initiatives (i.e. Symposia, roundtables) that support product strategy 
• Collaborate with Patient Advocacy to support development of patient-focused educational materials 
• Partner with Global and US Medical Affairs Leads to support alignment on program priorities and evidence gaps 
• Support the development Field Medical Affairs materials, both HCP and payor-focused 
• Maintain and update scientific communications platforms and materials  
• Maintain strong knowledge of relevant medical literature and data 

Education and Skills Requirements: 

• Doctorate degree (MD, PhD, PharmD) with 5+ years of relevant experience; rare disease or neuromuscular experience preferred 
• Strong analytical skills with ability to deliver against goals in collaborative, team-based environments 
• Ability to operate effectively within matrixed organizations and support cross-functional collaboration 
• Demonstrated ability to learn new disease areas or therapeutic modalities 
• Experience engaging with external experts and thought leaders 
• Experience working with external vendors or agencies 
• Excellent written and verbal communication skills 
• Proven ability to independently manage multiple complex projects in a fast-paced, dynamic environment 
• Strong strategic thinking skills with the ability to balance scientific, regulatory, and business considerations 
• Demonstrated ability to influence cross-functional stakeholders without direct authority 
• Highly collaborative team player with a strong cross-functional mindset 
• Meticulous attention to detail with a commitment to quality and compliance 
• Positive, proactive, and resilient team member who embodies Dyne’s Core Values  
• Passion for Dyne’s mission and excitement about contributing to the advancement of therapies for patients with serious diseases 
• Ability to drive timelines, meet firm deadlines, and adapt quickly to changing requirements and priorities 
• Embrace Dyne’s core values and culture 
• Excitement about the vision and mission of Dyne 
• Travel up to ~20% 

#LI-Onsite

Role Summary:

The Senior Director, Scientific Communications Lead - DMD provides leadership for the planning, development, and execution of an integrated scientific communications strategy for Dyne’s Duchenne muscular dystrophy program. This role is responsible for defining long-term strategies that translate complex scientific, clinical, and real-world data into clear, accurate, and compliant communications for internal and external stakeholders, including healthcare professionals and payers. The ideal candidate brings deep expertise in strategic scientific communication planning and cross-functional leadership ensuring close partnership with other functions withing the Global Medical Affairs team, as well as with Clinical Development, Biostatistics, Research, HEOR, Commercial, and Corporate Communications to ensure cohesive planning and execution of Dyne’s scientific and medical education strategy. 

This role is based in Waltham, MA. 
 
Primary Responsibilities Include:  

• Develop and lead the global scientific communications strategy for DMD aligned with program and corporate objectives 

• Develop and ensure the execution of a long-term strategic publication plan, including integration of preclinical, clinical, and real-world evidence data into dissemination roadmaps and evidence-generation narratives, and maintain visibility into timelines, dependencies and risks to ensure on-time delivery 

• Assist in developing Dyne’s overall congress strategy and presence, including planning medical booth assets, symposia, and presentations 

• Plan and execute global medical communications initiatives (e.g., IME, roundtables) that support product strategy 

• Serve as strategic advisor to cross-functional teams on scientific messaging and data interpretation 

• Partner closely with Patient Advocacy and regional medical teams on the development of publications and educational materials for their respective audiences 

• Manage agency partners and external vendors to deliver high-quality outputs 

• Manage budgets and resources to support long-term planning and execution 

• Mentor junior members of the team 

Education and Skills Requirements: 

• Doctorate degree (MD, PhD, PharmD) with 12+ years of experience with a focus on rare diseases, neuromuscular experience, or related discipline 

• Analytical skills, with a track record of delivering against goals while working in high performing, diverse teams 

• Demonstrated success in operating effectively in highly matrixed organizations where influencing skills are critical to day-to-day success 

• Experience in building strong and effective relationships with thought leaders 

• Experience in managing vendor partners 

• Excellent written and verbal communication skills 

• Launch experience preferred 

• Travel up to ~20%